Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Srp54a | Rat | Shwachman-Diamond syndrome | | ISO | SRP54 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Srp54a | Rat | Shwachman-Diamond syndrome | | ISO | SRP54 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
3. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
4. | GOA pipeline | RGD automated data pipeline |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
6. | Comprehensive gene review and curation | RGD comprehensive gene curation |
7. | Modulation of the signal recognition particle 54-kDa subunit (SRP54) in rat preosteoblasts by the extracellular matrix. | Traianedes K, etal., J Biol Chem 1995 Sep 8;270(36):20891-4. |
PMID:8247130 | PMID:8521805 | PMID:8622769 | PMID:9511762 | PMID:10618370 | PMID:12477932 | PMID:15489334 | PMID:16469117 | PMID:18089836 | PMID:22658674 | PMID:28972538 | PMID:31505169 |
Srp54a (Rattus norvegicus - Norway rat) |
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SRP54 (Homo sapiens - human) |
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Srp54a (Mus musculus - house mouse) |
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Srp54 (Chinchilla lanigera - long-tailed chinchilla) |
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LOC100987236 (Pan paniscus - bonobo/pygmy chimpanzee) |
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SRP54 (Canis lupus familiaris - dog) |
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LOC101965130 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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SRP54 (Sus scrofa - pig) |
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SRP54 (Chlorocebus sabaeus - green monkey) |
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Srp54 (Heterocephalus glaber - naked mole-rat) |
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Variants in Srp54a
277 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
D6Rat22 |
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D6Got311 |
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RH128735 |
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RH144431 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_053871 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006240097 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC115158 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BC079117 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473947 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ211580 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ225417 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000006 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
U29893 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000052076 ⟹ ENSRNOP00000048945 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000098782 ⟹ ENSRNOP00000085749 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_053871 ⟹ NP_446323 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006240097 ⟹ XP_006240159 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_446323 | (Get FASTA) | NCBI Sequence Viewer |
XP_006240159 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAB17124 | (Get FASTA) | NCBI Sequence Viewer |
AAH79117 | (Get FASTA) | NCBI Sequence Viewer | |
EDM03421 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000048945.3 | ||
ENSRNOP00000085749.1 | |||
ENSRNOP00055018709 | |||
ENSRNOP00060029034 | |||
GenBank Protein | Q6AYB5 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_446323 ⟸ NM_053871 |
- UniProtKB: | Q6AYB5 (UniProtKB/Swiss-Prot), A0A8I6A4J0 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006240159 ⟸ XM_006240097 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6A4J0 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000048945 ⟸ ENSRNOT00000052076 |
Ensembl Acc Id: | ENSRNOP00000085749 ⟸ ENSRNOT00000098782 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q6AYB5-F1-model_v2 | AlphaFold | Q6AYB5 | 1-504 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13694602 | ||||||||
Promoter ID: | EPDNEW_R5126 | ||||||||
Type: | initiation region | ||||||||
Name: | Srp54a_1 | ||||||||
Description: | signal recognition particle 54A | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:621390 | AgrOrtholog |
BioCyc Gene | G2FUF-37492 | BioCyc |
Ensembl Genes | ENSRNOG00000032776 | Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ENSRNOG00055013456 | UniProtKB/Swiss-Prot | |
ENSRNOG00060020394 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000052076.5 | UniProtKB/Swiss-Prot |
ENSRNOT00000098782.1 | UniProtKB/TrEMBL | |
ENSRNOT00055023065 | UniProtKB/Swiss-Prot | |
ENSRNOT00060035321 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 1.10.260.30 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
1.20.120.140 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
3.40.50.300 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7126297 | IMAGE-MGC_LOAD |
InterPro | AAA+_ATPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
P-loop_NTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Signal_recog_part_SRP54_M_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Signal_recog_particl_SRP54_hlx | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Signal_recog_particle_SRP54_M | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SRP54 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SRP54_euk | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SRP54_GTPase_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SRP54_N_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:116650 | UniProtKB/Swiss-Prot |
MGC_CLONE | MGC:94117 | IMAGE-MGC_LOAD |
NCBI Gene | 116650 | ENTREZGENE |
PANTHER | PTHR11564 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | SRP54 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SRP54_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SRP_SPB | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Srp54a | PhenoGen |
PROSITE | SRP54 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000032776 | RatGTEx |
ENSRNOG00055013456 | RatGTEx | |
ENSRNOG00060020394 | RatGTEx | |
SMART | AAA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SRP54 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SRP54_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | SSF47446 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF52540 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A8I6A4J0 | ENTREZGENE, UniProtKB/TrEMBL |
Q6AYB5 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2013-11-19 | Srp54a | signal recognition particle 54A | Srp54a | signal recognition particle 54kDa | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2013-11-11 | Srp54a | signal recognition particle 54kDa | Srp54 | signal recognition particle 54A | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2012-02-03 | Srp54 | signal recognition particle 54A | Srp54a | signal recognition particle 54a | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-05-15 | Srp54a | signal recognition particle 54a | Srp54 | signal recognition particle 54 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-07-08 | Srp54 | signal recognition particle 54 | signal recognition particle 54 kDa | Name updated | 1299863 | APPROVED | |
2002-08-07 | Srp54 | signal recognition particle 54 kDa | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_expression | mRNA expression increases in preosteoblastic cells subcultured on collagen compared with subculture on plastic only | 634092 |