Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Lpin1 (lipin 1) Rattus norvegicus
Analyze
Symbol: Lpin1
Name: lipin 1
Description: Predicted to have several functions, including RNA polymerase II transcription factor binding activity; histone deacetylase binding activity; and peroxisome proliferator activated receptor binding activity. Involved in animal organ regeneration and cellular response to insulin stimulus. Predicted to localize to the mitochondrial outer membrane; nuclear membrane; and transcription factor complex. Biomarker of end stage renal failure. Orthologous to human LPIN1 (lipin 1); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH (RS)-amphetamine; 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC313977; phosphatidate phosphatase LPIN1
Orthologs:
Homo sapiens (human) : LPIN1 (lipin 1)  HGNC  Alliance
Mus musculus (house mouse) : Lpin1 (lipin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lpin1 (lipin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LPIN1 (lipin 1)
Canis lupus familiaris (dog) : LPIN1 (lipin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lpin1 (lipin 1)
Sus scrofa (pig) : LPIN1 (lipin 1)
more info ...
Allele / Splice: Lpin1em1Mcwi  
Genetic Models: SS-Lpin1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0641,796,214 - 41,905,149 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0651,532,422 - 51,638,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4640,253,664 - 40,297,195 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1640,292,340 - 40,300,145 (-)NCBI
Celera638,623,057 - 38,690,436 (-)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lpin1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307646
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.