Asap2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2) - Rat Genome Database

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Gene: Asap2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2) Rattus norvegicus
Analyze
Symbol: Asap2
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
RGD ID: 1305263
Description: Predicted to enable GTPase activator activity. Predicted to be involved in positive regulation of GTPase activity. Predicted to be located in cytoplasm. Orthologous to human ASAP2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2); PARTICIPATES IN endocytosis pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Ddef2; development and differentiation enhancing factor 2; LOC362719
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2640,658,201 - 40,821,017 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0643,231,178 - 43,348,606 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,234,526 - 43,343,551 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,104,415 - 60,211,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4641,664,580 - 41,828,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1641,666,559 - 41,830,468 (+)NCBI
Celera639,948,323 - 40,108,106 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Asap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2640,658,201 - 40,821,017 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0643,231,178 - 43,348,606 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,234,526 - 43,343,551 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,104,415 - 60,211,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4641,664,580 - 41,828,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1641,666,559 - 41,830,468 (+)NCBI
Celera639,948,323 - 40,108,106 (+)NCBICelera
Cytogenetic Map6q16NCBI
ASAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3829,206,812 - 9,405,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl29,206,765 - 9,405,683 (+)EnsemblGRCh38hg38GRCh38
GRCh3729,346,941 - 9,545,807 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3629,264,345 - 9,463,257 (+)NCBINCBI36Build 36hg18NCBI36
Build 3429,297,491 - 9,496,404NCBI
Celera29,258,815 - 9,457,991 (+)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef29,193,261 - 9,391,244 (+)NCBIHuRef
CHM1_129,276,598 - 9,475,471 (+)NCBICHM1_1
T2T-CHM13v2.029,230,598 - 9,430,981 (+)NCBIT2T-CHM13v2.0
Asap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391221,161,369 - 21,320,172 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1221,040,460 - 21,320,172 (+)EnsemblGRCm39 Ensembl
GRCm381221,111,368 - 21,270,171 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1220,990,459 - 21,270,171 (+)EnsemblGRCm38mm10GRCm38
MGSCv371221,117,617 - 21,276,032 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361221,358,246 - 21,516,661 (+)NCBIMGSCv36mm8
Celera1219,634,768 - 19,791,722 (-)NCBICelera
Cytogenetic Map12A1.3NCBI
Asap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554874,994,901 - 5,131,293 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554874,994,901 - 5,133,751 (+)NCBIChiLan1.0ChiLan1.0
ASAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A9,433,276 - 9,559,410 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A9,430,515 - 9,557,067 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A9,196,409 - 9,395,914 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ASAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1176,350,030 - 6,523,579 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl176,349,621 - 6,522,030 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,277,942 - 6,451,367 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0176,448,861 - 6,622,380 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl176,447,287 - 6,622,378 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1176,341,607 - 6,514,914 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0176,343,720 - 6,517,334 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,357,255 - 6,530,694 (+)NCBIUU_Cfam_GSD_1.0
Asap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629250,936,131 - 51,047,286 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365325,654,614 - 5,802,332 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,920,978 - 127,082,932 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13126,920,972 - 127,082,947 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23135,296,092 - 135,436,317 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11498,244,584 - 98,451,017 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1498,246,944 - 98,450,719 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604513,876,873 - 14,079,137 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624969303,484 - 433,967 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624969301,573 - 434,008 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
BF388376  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,792,349 - 40,792,562 (+)MAPPERmRatBN7.2
Rnor_6.0643,319,271 - 43,319,483NCBIRnor6.0
Rnor_5.0660,188,095 - 60,188,307UniSTSRnor5.0
RGSC_v3.4834,658,368 - 34,658,580UniSTSRGSC3.4
RGSC_v3.4641,800,787 - 41,800,999UniSTSRGSC3.4
Celera640,079,344 - 40,079,556UniSTS
RH 3.4 Map6226.5UniSTS
Cytogenetic Map6q16UniSTS
BF405170  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,733,682 - 40,733,781 (+)MAPPERmRatBN7.2
Rnor_6.0643,253,449 - 43,253,547NCBIRnor6.0
Rnor_5.0660,122,218 - 60,122,316UniSTSRnor5.0
RGSC_v3.4641,739,971 - 41,740,069UniSTSRGSC3.4
Celera640,022,755 - 40,022,853UniSTS
RH 3.4 Map6215.4UniSTS
Cytogenetic Map6q16UniSTS
BE116838  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,820,796 - 40,820,979 (+)MAPPERmRatBN7.2
Rnor_6.0643,348,386 - 43,348,568NCBIRnor6.0
Rnor_5.0660,216,092 - 60,216,274UniSTSRnor5.0
RGSC_v3.4641,829,565 - 41,829,747UniSTSRGSC3.4
Celera640,107,886 - 40,108,068UniSTS
RH 3.4 Map6221.9UniSTS
Cytogenetic Map6q16UniSTS
fc63b12.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,677,950 - 40,678,279 (+)MAPPERmRatBN7.2
mRatBN7.2640,677,970 - 40,678,279 (+)MAPPERmRatBN7.2
Rnor_6.0643,197,254 - 43,197,562NCBIRnor6.0
Rnor_6.0643,197,234 - 43,197,562NCBIRnor6.0
Rnor_5.0660,066,961 - 60,067,269UniSTSRnor5.0
Rnor_5.0660,066,941 - 60,067,269UniSTSRnor5.0
RGSC_v3.4641,684,502 - 41,684,830UniSTSRGSC3.4
RGSC_v3.4641,684,522 - 41,684,830UniSTSRGSC3.4
Celera639,967,862 - 39,968,170UniSTS
Celera639,967,842 - 39,968,170UniSTS
Cytogenetic Map6q16UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:399
Count of miRNA genes:99
Interacting mature miRNAs:103
Transcripts:ENSRNOT00000008173, ENSRNOT00000031371, ENSRNOT00000060408, ENSRNOT00000068301
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 42 4 4 1 4 74 33 31 11
Low 2 1 53 37 18 37 8 11 2 10 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000086808   ⟹   ENSRNOP00000074423
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,734,223 - 40,816,128 (+)Ensembl
Rnor_6.0 Ensembl643,234,526 - 43,343,551 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101416   ⟹   ENSRNOP00000078581
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109737   ⟹   ENSRNOP00000080769
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110023   ⟹   ENSRNOP00000095612
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119000   ⟹   ENSRNOP00000096020
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)Ensembl
RefSeq Acc Id: XM_039113143   ⟹   XP_038969071
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,658,201 - 40,821,017 (+)NCBI
RefSeq Acc Id: XM_039113144   ⟹   XP_038969072
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,658,201 - 40,821,017 (+)NCBI
RefSeq Acc Id: XM_039113145   ⟹   XP_038969073
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,658,201 - 40,821,017 (+)NCBI
RefSeq Acc Id: XM_039113146   ⟹   XP_038969074
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,658,201 - 40,821,017 (+)NCBI
RefSeq Acc Id: XM_039113147   ⟹   XP_038969075
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,658,201 - 40,804,309 (+)NCBI
RefSeq Acc Id: XM_039113148   ⟹   XP_038969076
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,774,905 - 40,821,017 (+)NCBI
RefSeq Acc Id: XM_039113150   ⟹   XP_038969078
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,658,201 - 40,727,621 (+)NCBI
RefSeq Acc Id: XR_005505822
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2640,658,201 - 40,816,804 (+)NCBI
Reference Sequences
RefSeq Acc Id: ENSRNOP00000074423   ⟸   ENSRNOT00000086808
RefSeq Acc Id: XP_038969071   ⟸   XM_039113143
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038969073   ⟸   XM_039113145
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038969072   ⟸   XM_039113144
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038969074   ⟸   XM_039113146
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038969075   ⟸   XM_039113147
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038969078   ⟸   XM_039113150
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038969076   ⟸   XM_039113148
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000095612   ⟸   ENSRNOT00000110023
RefSeq Acc Id: ENSRNOP00000096020   ⟸   ENSRNOT00000119000
RefSeq Acc Id: ENSRNOP00000080769   ⟸   ENSRNOT00000109737
RefSeq Acc Id: ENSRNOP00000078581   ⟸   ENSRNOT00000101416
Protein Domains
Arf-GAP   PH   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K808-F1-model_v2 AlphaFold A0A0G2K808 1-844 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305263 AgrOrtholog
BioCyc Gene G2FUF-38044 BioCyc
Ensembl Genes ENSRNOG00000061519 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000074423.2 UniProtKB/TrEMBL
  ENSRNOP00000078581 ENTREZGENE
  ENSRNOP00000078581.1 UniProtKB/TrEMBL
  ENSRNOP00000080769 ENTREZGENE
  ENSRNOP00000080769.1 UniProtKB/TrEMBL
  ENSRNOP00000095612.1 UniProtKB/TrEMBL
  ENSRNOP00000096020 ENTREZGENE
  ENSRNOP00000096020.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000086808 ENTREZGENE
  ENSRNOT00000086808.2 UniProtKB/TrEMBL
  ENSRNOT00000101416 ENTREZGENE
  ENSRNOT00000101416.1 UniProtKB/TrEMBL
  ENSRNOT00000109737 ENTREZGENE
  ENSRNOT00000109737.1 UniProtKB/TrEMBL
  ENSRNOT00000110023.1 UniProtKB/TrEMBL
  ENSRNOT00000119000 ENTREZGENE
  ENSRNOT00000119000.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.150 UniProtKB/TrEMBL
  1.20.1270.60 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro AH/BAR-dom UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  ArfGAP UniProtKB/TrEMBL
  ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
  ASAP UniProtKB/TrEMBL
  ASAP2_SH3 UniProtKB/TrEMBL
  PH_ASAP UniProtKB/TrEMBL
  PH_dom-like UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene 362719 ENTREZGENE
PANTHER PTHR45854 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  ArfGap UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PhenoGen Asap2 PhenoGen
PRINTS REVINTRACTNG UniProtKB/TrEMBL
PROSITE ANK_REPEAT UniProtKB/TrEMBL
  ARFGAP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  ArfGap UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
  SSF57863 UniProtKB/TrEMBL
UniProt A0A0G2K808_RAT UniProtKB/TrEMBL
  A0A8I5ZL33_RAT UniProtKB/TrEMBL
  A0A8I5ZRL8_RAT UniProtKB/TrEMBL
  A0A8I6GLF1_RAT UniProtKB/TrEMBL
  A0A8I6GLQ2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-15 Asap2  ArfGAP with SH3 domain, ankyrin repeat and PH domain 2  Ddef2  development and differentiation enhancing factor 2   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ddef2  development and differentiation enhancing factor 2   Ddef2_predicted  development and differentiation enhancing factor 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ddef2_predicted  development and differentiation enhancing factor 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED