Asap2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2) - Rat Genome Database

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Gene: Asap2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2) Rattus norvegicus
Analyze
Symbol: Asap2
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
RGD ID: 1305263
Description: Predicted to enable GTPase activator activity. Predicted to be located in cytosol and plasma membrane. Orthologous to human ASAP2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2); PARTICIPATES IN endocytosis pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Ddef2; development and differentiation enhancing factor 2; LOC362719
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8646,386,605 - 46,549,669 (+)NCBIGRCr8
mRatBN7.2640,658,201 - 40,821,017 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0643,231,178 - 43,348,606 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,234,526 - 43,343,551 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,104,415 - 60,211,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4641,664,580 - 41,828,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1641,666,559 - 41,830,468 (+)NCBI
Celera639,948,323 - 40,108,106 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
plasma membrane  (ISO)
synapse  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Asap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8646,386,605 - 46,549,669 (+)NCBIGRCr8
mRatBN7.2640,658,201 - 40,821,017 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0643,231,178 - 43,348,606 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl643,234,526 - 43,343,551 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0660,104,415 - 60,211,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4641,664,580 - 41,828,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1641,666,559 - 41,830,468 (+)NCBI
Celera639,948,323 - 40,108,106 (+)NCBICelera
Cytogenetic Map6q16NCBI
ASAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3829,206,812 - 9,405,678 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl29,206,765 - 9,405,683 (+)EnsemblGRCh38hg38GRCh38
GRCh3729,346,941 - 9,545,807 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3629,264,345 - 9,463,257 (+)NCBINCBI36Build 36hg18NCBI36
Build 3429,297,491 - 9,496,404NCBI
Celera29,258,815 - 9,457,991 (+)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef29,193,261 - 9,391,244 (+)NCBIHuRef
CHM1_129,276,598 - 9,475,471 (+)NCBICHM1_1
T2T-CHM13v2.029,230,598 - 9,430,981 (+)NCBIT2T-CHM13v2.0
Asap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391221,161,369 - 21,320,172 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1221,040,460 - 21,320,172 (+)EnsemblGRCm39 Ensembl
GRCm381221,111,368 - 21,270,171 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1220,990,459 - 21,270,171 (+)EnsemblGRCm38mm10GRCm38
MGSCv371221,117,617 - 21,276,032 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361221,358,246 - 21,516,661 (+)NCBIMGSCv36mm8
Celera1219,634,768 - 19,791,722 (-)NCBICelera
Cytogenetic Map12A1.3NCBI
cM Map128.29NCBI
Asap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554874,994,901 - 5,131,293 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554874,994,901 - 5,133,751 (+)NCBIChiLan1.0ChiLan1.0
ASAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212117,120,591 - 117,320,110 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A117,124,564 - 117,324,073 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A9,196,409 - 9,395,914 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A9,433,276 - 9,559,410 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A9,430,515 - 9,557,067 (+)Ensemblpanpan1.1panPan2
ASAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1176,350,030 - 6,523,579 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl176,349,621 - 6,522,030 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha176,277,942 - 6,451,367 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0176,448,861 - 6,622,380 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl176,447,287 - 6,622,378 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1176,341,607 - 6,514,914 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0176,343,720 - 6,517,334 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0176,357,255 - 6,530,694 (+)NCBIUU_Cfam_GSD_1.0
Asap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629250,936,131 - 51,047,286 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365325,702,783 - 5,799,964 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365325,654,614 - 5,802,332 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3126,920,978 - 127,082,932 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13126,920,972 - 127,082,947 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23135,296,092 - 135,436,317 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ASAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11498,244,584 - 98,451,017 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1498,246,944 - 98,450,719 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604513,876,873 - 14,079,137 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624969303,484 - 433,967 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624969301,573 - 434,008 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Asap2
1083 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:399
Count of miRNA genes:99
Interacting mature miRNAs:103
Transcripts:ENSRNOT00000008173, ENSRNOT00000031371, ENSRNOT00000060408, ENSRNOT00000068301
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
8693632Alc27Alcohol consumption QTL 272.20.791drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)63432335751121479Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat

Markers in Region
BF388376  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,792,349 - 40,792,562 (+)MAPPERmRatBN7.2
Rnor_6.0643,319,271 - 43,319,483NCBIRnor6.0
Rnor_5.0660,188,095 - 60,188,307UniSTSRnor5.0
RGSC_v3.4834,658,368 - 34,658,580UniSTSRGSC3.4
RGSC_v3.4641,800,787 - 41,800,999UniSTSRGSC3.4
Celera640,079,344 - 40,079,556UniSTS
RH 3.4 Map6226.5UniSTS
Cytogenetic Map6q16UniSTS
BF405170  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,733,682 - 40,733,781 (+)MAPPERmRatBN7.2
Rnor_6.0643,253,449 - 43,253,547NCBIRnor6.0
Rnor_5.0660,122,218 - 60,122,316UniSTSRnor5.0
RGSC_v3.4641,739,971 - 41,740,069UniSTSRGSC3.4
Celera640,022,755 - 40,022,853UniSTS
RH 3.4 Map6215.4UniSTS
Cytogenetic Map6q16UniSTS
BE116838  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,820,796 - 40,820,979 (+)MAPPERmRatBN7.2
Rnor_6.0643,348,386 - 43,348,568NCBIRnor6.0
Rnor_5.0660,216,092 - 60,216,274UniSTSRnor5.0
RGSC_v3.4641,829,565 - 41,829,747UniSTSRGSC3.4
Celera640,107,886 - 40,108,068UniSTS
RH 3.4 Map6221.9UniSTS
Cytogenetic Map6q16UniSTS
fc63b12.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2640,677,950 - 40,678,279 (+)MAPPERmRatBN7.2
mRatBN7.2640,677,970 - 40,678,279 (+)MAPPERmRatBN7.2
Rnor_6.0643,197,254 - 43,197,562NCBIRnor6.0
Rnor_6.0643,197,234 - 43,197,562NCBIRnor6.0
Rnor_5.0660,066,961 - 60,067,269UniSTSRnor5.0
Rnor_5.0660,066,941 - 60,067,269UniSTSRnor5.0
RGSC_v3.4641,684,502 - 41,684,830UniSTSRGSC3.4
RGSC_v3.4641,684,522 - 41,684,830UniSTSRGSC3.4
Celera639,967,862 - 39,968,170UniSTS
Celera639,967,842 - 39,968,170UniSTS
Cytogenetic Map6q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000086808   ⟹   ENSRNOP00000074423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,734,223 - 40,816,128 (+)Ensembl
Rnor_6.0 Ensembl643,234,526 - 43,343,551 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101416   ⟹   ENSRNOP00000078581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109737   ⟹   ENSRNOP00000080769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110023   ⟹   ENSRNOP00000095612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119000   ⟹   ENSRNOP00000096020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl640,657,880 - 40,820,975 (+)Ensembl
RefSeq Acc Id: NM_001108704   ⟹   NP_001102174
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,386,605 - 46,549,669 (+)NCBI
RefSeq Acc Id: XM_039113144   ⟹   XP_038969072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,386,649 - 46,549,669 (+)NCBI
mRatBN7.2640,658,201 - 40,821,017 (+)NCBI
RefSeq Acc Id: XM_039113150   ⟹   XP_038969078
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,386,614 - 46,456,257 (+)NCBI
mRatBN7.2640,658,201 - 40,727,621 (+)NCBI
RefSeq Acc Id: XM_063262069   ⟹   XP_063118139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,386,646 - 46,549,669 (+)NCBI
RefSeq Acc Id: XM_063262070   ⟹   XP_063118140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,386,649 - 46,549,669 (+)NCBI
RefSeq Acc Id: XM_063262071   ⟹   XP_063118141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,386,650 - 46,532,964 (+)NCBI
RefSeq Acc Id: XM_063262072   ⟹   XP_063118142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,502,746 - 46,549,669 (+)NCBI
RefSeq Acc Id: XR_010052116
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8646,386,651 - 46,545,454 (+)NCBI
Ensembl Acc Id: ENSRNOP00000074423   ⟸   ENSRNOT00000086808
RefSeq Acc Id: XP_038969072   ⟸   XM_039113144
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GLF1 (UniProtKB/TrEMBL),   A0A8I5ZRL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038969078   ⟸   XM_039113150
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000095612   ⟸   ENSRNOT00000110023
Ensembl Acc Id: ENSRNOP00000096020   ⟸   ENSRNOT00000119000
Ensembl Acc Id: ENSRNOP00000080769   ⟸   ENSRNOT00000109737
Ensembl Acc Id: ENSRNOP00000078581   ⟸   ENSRNOT00000101416
RefSeq Acc Id: NP_001102174   ⟸   NM_001108704
- UniProtKB: A0A8I5ZRL8 (UniProtKB/TrEMBL),   A0A8I5ZL33 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118139   ⟸   XM_063262069
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZRL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118140   ⟸   XM_063262070
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZRL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118141   ⟸   XM_063262071
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063118142   ⟸   XM_063262072
- Peptide Label: isoform X5
- UniProtKB: A6HAV4 (UniProtKB/TrEMBL)
Protein Domains
Arf-GAP   PH   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K808-F1-model_v2 AlphaFold A0A0G2K808 1-844 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305263 AgrOrtholog
BioCyc Gene G2FUF-38044 BioCyc
Ensembl Genes ENSRNOG00000061519 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000086808.2 UniProtKB/TrEMBL
  ENSRNOT00000101416.1 UniProtKB/TrEMBL
  ENSRNOT00000109737.1 UniProtKB/TrEMBL
  ENSRNOT00000110023.1 UniProtKB/TrEMBL
  ENSRNOT00000119000.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.150 UniProtKB/TrEMBL
  1.20.1270.60 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  1.25.40.950 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro AH/BAR-dom UniProtKB/TrEMBL
  Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  ArfGAP UniProtKB/TrEMBL
  ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
  ASAP UniProtKB/TrEMBL
  ASAP2_SH3 UniProtKB/TrEMBL
  BAR_dom UniProtKB/TrEMBL
  PH_ASAP UniProtKB/TrEMBL
  PH_dom-like UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene 362719 ENTREZGENE
PANTHER ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  PTHR45854 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  ArfGap UniProtKB/TrEMBL
  BAR_3 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PhenoGen Asap2 PhenoGen
PRINTS REVINTRACTNG UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  ARFGAP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000061519 RatGTEx
SMART ANK UniProtKB/TrEMBL
  ArfGap UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF103657 UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
  SSF57863 UniProtKB/TrEMBL
UniProt A0A0G2K808_RAT UniProtKB/TrEMBL
  A0A8I5ZL33 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZRL8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLQ2_RAT UniProtKB/TrEMBL
  A6HAV4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-15 Asap2  ArfGAP with SH3 domain, ankyrin repeat and PH domain 2  Ddef2  development and differentiation enhancing factor 2   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ddef2  development and differentiation enhancing factor 2   Ddef2_predicted  development and differentiation enhancing factor 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ddef2_predicted  development and differentiation enhancing factor 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED