Lamb1 (laminin subunit beta 1) - Rat Genome Database

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Gene: Lamb1 (laminin subunit beta 1) Rattus norvegicus
Analyze
Symbol: Lamb1
Name: laminin subunit beta 1
RGD ID: 1306311
Description: Predicted to enable enzyme binding activity; glycosphingolipid binding activity; and integrin binding activity. Predicted to be a structural constituent of synapse-associated extracellular matrix. Predicted to be an extracellular matrix structural constituent. Predicted to be involved in several processes, including basement membrane assembly; neurogenesis; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within embryo implantation and neuron projection development. Located in collagen-containing extracellular matrix. Human ortholog(s) of this gene implicated in autistic disorder and lissencephaly 5. Orthologous to human LAMB1 (laminin subunit beta 1); INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Lamb1-1; laminin B1 subunit 1; laminin subunit beta-1; laminin, beta 1; LOC298941
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8653,562,849 - 53,630,118 (+)NCBIGRCr8
mRatBN7.2647,835,492 - 47,902,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl647,835,525 - 47,902,585 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0650,528,796 - 50,596,593 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl650,528,823 - 50,596,079 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0659,204,031 - 59,271,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4649,115,671 - 49,183,374 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1649,109,263 - 49,186,072 (+)NCBI
Celera647,038,296 - 47,105,077 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-bromohexadecanoic acid  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (EXP)
acetic acid  (ISO)
acrolein  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
bazedoxifene  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (ISO)
bilirubin IXalpha  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromochloroacetic acid  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
chloropicrin  (ISO)
chloroquine  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dieldrin  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enalapril  (EXP)
ethyl methanesulfonate  (ISO)
fenamidone  (ISO)
fipronil  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glyphosate  (EXP)
griseofulvin  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
lactacystin  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury(1+)  (ISO)
miconazole  (ISO)
mitoxantrone  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nicotine  (ISO)
nitrofen  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
ochratoxin A  (ISO)
oleic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
potassium chromate  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dodecyl sulfate  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Mutation screening and association analysis of six candidate genes for autism on chromosome 7q. Bonora E, etal., Eur J Hum Genet. 2005 Feb;13(2):198-207.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Laminin-6 assembles into multimolecular fibrillar complexes with perlecan and participates in mechanical-signal transduction via a dystroglycan-dependent, integrin-independent mechanism. Jones JC, etal., J Cell Sci. 2005 Jun 15;118(Pt 12):2557-66. Epub 2005 May 31.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:1292752   PMID:2099832   PMID:7639691   PMID:8034675   PMID:9004048   PMID:9264260   PMID:9299121   PMID:9396756   PMID:10444590   PMID:10964500   PMID:12631063   PMID:12743034  
PMID:14557481   PMID:15102706   PMID:15207330   PMID:15474030   PMID:15894315   PMID:15895400   PMID:16041630   PMID:16236823   PMID:16289578   PMID:16554364   PMID:16631359   PMID:18691079  
PMID:18757743   PMID:19118221   PMID:20301201   PMID:21362503   PMID:21849984   PMID:23154389   PMID:23472759   PMID:23658023   PMID:24006456   PMID:27068509   PMID:27559042   PMID:30361391  


Genomics

Comparative Map Data
Lamb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8653,562,849 - 53,630,118 (+)NCBIGRCr8
mRatBN7.2647,835,492 - 47,902,585 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl647,835,525 - 47,902,585 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0650,528,796 - 50,596,593 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl650,528,823 - 50,596,079 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0659,204,031 - 59,271,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4649,115,671 - 49,183,374 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1649,109,263 - 49,186,072 (+)NCBI
Celera647,038,296 - 47,105,077 (+)NCBICelera
Cytogenetic Map6q16NCBI
LAMB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387107,923,799 - 108,003,161 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7107,923,799 - 108,003,213 (-)EnsemblGRCh38hg38GRCh38
GRCh377107,564,244 - 107,643,606 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367107,351,499 - 107,431,040 (-)NCBINCBI36Build 36hg18NCBI36
Build 347107,158,213 - 107,237,755NCBI
Celera7102,371,233 - 102,450,770 (-)NCBICelera
Cytogenetic Map7q31.1NCBI
HuRef7101,926,690 - 102,006,298 (-)NCBIHuRef
CHM1_17107,497,967 - 107,577,516 (-)NCBICHM1_1
T2T-CHM13v2.07109,241,996 - 109,321,407 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27106,925,375 - 107,004,933 (-)NCBI
Lamb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391231,315,230 - 31,379,643 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1231,315,233 - 31,379,643 (+)EnsemblGRCm39 Ensembl
GRCm381231,265,146 - 31,329,644 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1231,265,234 - 31,329,644 (+)EnsemblGRCm38mm10GRCm38
MGSCv371231,950,159 - 32,014,504 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361231,851,443 - 31,915,700 (+)NCBIMGSCv36mm8
Celera1232,713,386 - 32,777,732 (+)NCBICelera
Cytogenetic Map12A2NCBI
cM Map1213.39NCBI
Lamb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541012,241,235 - 12,305,433 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541012,241,235 - 12,305,433 (-)NCBIChiLan1.0ChiLan1.0
LAMB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26144,769,878 - 144,849,511 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17193,039,847 - 193,120,895 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0799,905,761 - 99,985,233 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17112,627,488 - 112,706,554 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7112,627,488 - 112,706,554 (-)Ensemblpanpan1.1panPan2
LAMB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11812,634,640 - 12,700,311 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1812,630,554 - 12,700,308 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1812,273,909 - 12,344,544 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01812,901,205 - 12,971,843 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1812,886,065 - 13,160,390 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11812,719,649 - 12,788,770 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01812,639,931 - 12,709,079 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01812,866,134 - 12,936,827 (+)NCBIUU_Cfam_GSD_1.0
Lamb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511855,053,363 - 55,121,513 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647916,177,158 - 16,247,165 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647916,177,200 - 16,245,268 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9107,671,152 - 107,772,269 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19107,670,120 - 107,747,242 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29118,440,049 - 118,515,695 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LAMB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12176,829,287 - 76,914,348 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2176,829,443 - 76,914,324 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604226,949,313 - 27,034,081 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lamb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473921,771,226 - 21,843,884 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473921,771,617 - 21,843,888 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lamb1
429 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:76
Interacting mature miRNAs:87
Transcripts:ENSRNOT00000008321
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat

Markers in Region
RH126801  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2647,848,771 - 47,849,080 (+)MAPPERmRatBN7.2
Rnor_6.0650,542,059 - 50,542,367NCBIRnor6.0
Rnor_5.0659,217,286 - 59,217,594UniSTSRnor5.0
RGSC_v3.4649,128,881 - 49,129,189UniSTSRGSC3.4
Celera647,051,556 - 47,051,864UniSTS
Cytogenetic Map6q16UniSTS
RH137828  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2647,902,338 - 47,902,485 (+)MAPPERmRatBN7.2
Rnor_6.0650,595,863 - 50,596,009NCBIRnor6.0
Rnor_5.0659,271,090 - 59,271,236UniSTSRnor5.0
RGSC_v3.4649,182,851 - 49,182,997UniSTSRGSC3.4
Celera647,104,347 - 47,104,493UniSTS
Cytogenetic Map6q16UniSTS
UniSTS:236828  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2647,899,414 - 47,899,551 (+)MAPPERmRatBN7.2
Rnor_6.0650,592,927 - 50,593,063NCBIRnor6.0
Rnor_5.0659,268,154 - 59,268,290UniSTSRnor5.0
RGSC_v3.4649,179,922 - 49,180,058UniSTSRGSC3.4
Celera647,101,423 - 47,101,559UniSTS
Cytogenetic Map6q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000008321   ⟹   ENSRNOP00000008321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl647,835,559 - 47,902,581 (+)Ensembl
Rnor_6.0 Ensembl650,528,823 - 50,596,079 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095840   ⟹   ENSRNOP00000080442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl647,835,564 - 47,902,585 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099819   ⟹   ENSRNOP00000082136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl647,835,525 - 47,902,565 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114806   ⟹   ENSRNOP00000085325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl647,836,128 - 47,902,581 (+)Ensembl
RefSeq Acc Id: NM_001106721   ⟹   NP_001100191
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8653,563,096 - 53,630,118 (+)NCBI
RefSeq Acc Id: XM_003750137   ⟹   XP_003750185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8653,563,028 - 53,630,114 (+)NCBI
mRatBN7.2647,835,519 - 47,902,585 (+)NCBI
Rnor_6.0650,528,804 - 50,596,593 (+)NCBI
Rnor_5.0659,204,031 - 59,271,336 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239997   ⟹   XP_006240059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8653,563,050 - 53,630,114 (+)NCBI
mRatBN7.2647,835,515 - 47,902,585 (+)NCBI
Rnor_6.0650,528,804 - 50,596,593 (+)NCBI
Rnor_5.0659,204,031 - 59,271,336 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063261658   ⟹   XP_063117728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8653,562,849 - 53,630,114 (+)NCBI
RefSeq Acc Id: XP_003750185   ⟸   XM_003750137
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZQ25 (UniProtKB/TrEMBL),   A0A8I6A3T2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240059   ⟸   XM_006239997
- Peptide Label: isoform X2
- UniProtKB: D3ZQN7 (UniProtKB/TrEMBL),   A0A8I6A3T2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000008321   ⟸   ENSRNOT00000008321
Ensembl Acc Id: ENSRNOP00000080442   ⟸   ENSRNOT00000095840
Ensembl Acc Id: ENSRNOP00000085325   ⟸   ENSRNOT00000114806
Ensembl Acc Id: ENSRNOP00000082136   ⟸   ENSRNOT00000099819
RefSeq Acc Id: XP_063117728   ⟸   XM_063261658
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A3T2 (UniProtKB/TrEMBL),   D3ZQN7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001100191   ⟸   NM_001106721
- Peptide Label: precursor
- UniProtKB: D3ZQN7 (UniProtKB/TrEMBL),   A0A8I6A3T2 (UniProtKB/TrEMBL)
Protein Domains
Laminin EGF-like   Laminin IV type B   Laminin N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQN7-F1-model_v2 AlphaFold D3ZQN7 1-1786 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694550
Promoter ID:EPDNEW_R5065
Type:initiation region
Name:Lamb1_1
Description:laminin subunit beta 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0650,528,852 - 50,528,912EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306311 AgrOrtholog
BioCyc Gene G2FUF-37922 BioCyc
Ensembl Genes ENSRNOG00000005678 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008321.8 UniProtKB/TrEMBL
  ENSRNOT00000095840.1 UniProtKB/TrEMBL
  ENSRNOT00000099819.1 UniProtKB/TrEMBL
  ENSRNOT00000114806.1 UniProtKB/TrEMBL
Gene3D-CATH Galactose-binding domain-like UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  EGF_laminin UniProtKB/TrEMBL
  Laminin/Netrin_ECM UniProtKB/TrEMBL
  Laminin_IV UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
NCBI Gene 298941 ENTREZGENE
PANTHER LAMININ SUBUNIT GAMMA-1 UniProtKB/TrEMBL
  NETRIN/LAMININ-RELATED UniProtKB/TrEMBL
  WING BLISTER, ISOFORM B UniProtKB/TrEMBL
Pfam Laminin_EGF UniProtKB/TrEMBL
  LAMININ_IV_B UniProtKB/TrEMBL
  Laminin_N UniProtKB/TrEMBL
PhenoGen Lamb1 PhenoGen
PRINTS EGFLAMININ UniProtKB/TrEMBL
PROSITE EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  LAMININ_IVB UniProtKB/TrEMBL
  LAMININ_NTER UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005678 RatGTEx
SMART EGF UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  LamNT UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  Tropomyosin UniProtKB/TrEMBL
UniProt A0A8I5ZQ25 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZVQ5_RAT UniProtKB/TrEMBL
  A0A8I6A3T2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQN7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Lamb1  laminin subunit beta 1  Lamb1  laminin, beta 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Lamb1  laminin, beta 1  Lamb1_predicted  laminin, beta 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Lamb1_predicted  laminin, beta 1 (predicted)  Lamb1-1_predicted  laminin B1 subunit 1 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Lamb1-1_predicted  laminin B1 subunit 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED