Meox2 (mesenchyme homeobox 2) - Rat Genome Database

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Gene: Meox2 (mesenchyme homeobox 2) Rattus norvegicus
Analyze
Symbol: Meox2
Name: mesenchyme homeobox 2
RGD ID: 3079
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in fibroblast proliferation and myofibroblast differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Biomarker of myocardial infarction. Orthologous to human MEOX2 (mesenchyme homeobox 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: growth arrest-specific homeobox; homeobox protein MOX-2; mesenchyme homeo box 2; mesenchyme homeo box 2 (growth arrest-specific homeo box)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8659,584,025 - 59,644,722 (+)NCBIGRCr8
mRatBN7.2653,856,760 - 53,917,467 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl653,856,758 - 53,917,467 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx654,156,909 - 54,224,375 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0654,471,799 - 54,539,259 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0653,944,436 - 54,011,867 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0656,625,768 - 56,689,195 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl656,625,650 - 56,689,238 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0666,231,865 - 66,293,008 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4655,895,760 - 55,957,066 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1655,898,885 - 55,960,192 (+)NCBI
Celera652,995,636 - 53,056,305 (+)NCBICelera
Cytogenetic Map6q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,7-dihydropurine-6-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
chloroprene  (ISO)
chlorpyrifos  (ISO)
Cuprizon  (EXP)
dibutyl phthalate  (ISO)
dichlorine  (EXP)
diethylstilbestrol  (EXP,ISO)
dioxygen  (ISO)
fentin chloride  (EXP)
furan  (EXP)
gamma-hexachlorocyclohexane  (EXP)
glycidol  (EXP)
hydrogen cyanide  (ISO)
lipopolysaccharide  (ISO)
melphalan  (ISO)
mercaptopurine  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
mirex  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nevirapine  (EXP)
nickel atom  (ISO)
ozone  (EXP)
paracetamol  (ISO)
PCB138  (ISO)
phenobarbital  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
Pirarubicin  (EXP)
pirinixic acid  (EXP,ISO)
potassium cyanide  (ISO)
purine-6-thiol  (EXP)
rofecoxib  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
troglitazone  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
nuclear speck  (IEA)
nucleus  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. The Ski-Zeb2-Meox2 pathway provides a novel mechanism for regulation of the cardiac myofibroblast phenotype. Cunnington RH, etal., J Cell Sci. 2014 Jan 1;127(Pt 1):40-9. doi: 10.1242/jcs.126722. Epub 2013 Oct 23.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells. Gorski DH, etal., Mol Cell Biol 1993 Jun;13(6):3722-33.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:9073066   PMID:10403250   PMID:12925591   PMID:15680482   PMID:16116430   PMID:16284941   PMID:16335786   PMID:17074759   PMID:20160044   PMID:20421348   PMID:20516212   PMID:22166940  
PMID:22206000   PMID:25280940   PMID:36713029  


Genomics

Comparative Map Data
Meox2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8659,584,025 - 59,644,722 (+)NCBIGRCr8
mRatBN7.2653,856,760 - 53,917,467 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl653,856,758 - 53,917,467 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx654,156,909 - 54,224,375 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0654,471,799 - 54,539,259 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0653,944,436 - 54,011,867 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0656,625,768 - 56,689,195 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl656,625,650 - 56,689,238 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0666,231,865 - 66,293,008 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4655,895,760 - 55,957,066 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1655,898,885 - 55,960,192 (+)NCBI
Celera652,995,636 - 53,056,305 (+)NCBICelera
Cytogenetic Map6q21NCBI
MEOX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38715,611,212 - 15,686,683 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl715,611,212 - 15,686,683 (-)EnsemblGRCh38hg38GRCh38
GRCh37715,650,837 - 15,726,308 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36715,617,362 - 15,692,833 (-)NCBINCBI36Build 36hg18NCBI36
Build 34715,424,076 - 15,499,534NCBI
Celera715,630,544 - 15,706,034 (-)NCBICelera
Cytogenetic Map7p21.2NCBI
HuRef715,535,672 - 15,611,245 (-)NCBIHuRef
CHM1_1715,650,236 - 15,725,903 (-)NCBICHM1_1
T2T-CHM13v2.0715,744,456 - 15,819,945 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2715,703,946 - 15,779,448 (-)NCBI
Meox2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391237,158,539 - 37,229,533 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1237,158,539 - 37,229,533 (+)EnsemblGRCm39 Ensembl
GRCm381237,108,540 - 37,179,534 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1237,108,540 - 37,179,534 (+)EnsemblGRCm38mm10GRCm38
MGSCv371237,835,133 - 37,906,115 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361237,618,812 - 37,689,794 (+)NCBIMGSCv36mm8
Celera1238,548,347 - 38,608,374 (+)NCBICelera
Cytogenetic Map12A3NCBI
cM Map1216.84NCBI
Meox2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541018,924,605 - 18,988,478 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541018,924,669 - 18,988,478 (-)NCBIChiLan1.0ChiLan1.0
MEOX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2620,447,134 - 20,522,883 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1768,769,680 - 68,847,538 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0716,268,225 - 16,343,914 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1715,598,460 - 15,673,935 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl715,598,466 - 15,673,935 (-)Ensemblpanpan1.1panPan2
MEOX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11430,258,737 - 30,324,438 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1429,864,318 - 30,324,006 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1429,780,887 - 29,846,794 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01430,174,433 - 30,240,144 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1430,174,125 - 30,239,967 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11430,276,649 - 30,342,528 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01429,996,478 - 30,062,402 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01430,307,318 - 30,373,202 (-)NCBIUU_Cfam_GSD_1.0
Meox2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511874,564,415 - 74,629,128 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365462,239,442 - 2,304,099 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365462,239,442 - 2,304,099 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEOX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl984,943,199 - 85,010,157 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1984,945,178 - 85,009,939 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2993,770,697 - 93,771,213 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MEOX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12142,403,474 - 42,476,469 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2142,403,741 - 42,476,453 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604262,025,173 - 62,098,121 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Meox2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473914,483,789 - 14,547,374 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473914,483,750 - 14,547,491 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Meox2
665 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:380
Count of miRNA genes:207
Interacting mature miRNAs:244
Transcripts:ENSRNOT00000008803
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)63569161857730540Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat

Markers in Region
D6Rat205  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2653,913,918 - 53,914,055 (+)MAPPERmRatBN7.2
Rnor_6.0656,685,647 - 56,685,783NCBIRnor6.0
Rnor_5.0666,289,460 - 66,289,596UniSTSRnor5.0
RGSC_v3.4655,953,517 - 55,953,654RGDRGSC3.4
RGSC_v3.4655,953,518 - 55,953,654UniSTSRGSC3.4
RGSC_v3.1655,956,643 - 55,956,780RGD
Celera653,052,757 - 53,052,893UniSTS
SHRSP x BN Map640.9199RGD
SHRSP x BN Map640.9199UniSTS
Cytogenetic Map6q21UniSTS
AI598524  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2653,917,008 - 53,917,177 (+)MAPPERmRatBN7.2
Rnor_6.0656,688,737 - 56,688,905NCBIRnor6.0
Rnor_5.0666,292,550 - 66,292,718UniSTSRnor5.0
RGSC_v3.4655,956,608 - 55,956,776UniSTSRGSC3.4
Celera653,055,847 - 53,056,015UniSTS
RH 3.4 Map6383.4UniSTS
Cytogenetic Map6q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 15 2 2 6 6 6 5 11 6
Low 2 18 45 31 7 31 2 5 16 18 29 2
Below cutoff 1 6 10 10 9 10 58 10 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000008803   ⟹   ENSRNOP00000008803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl653,856,758 - 53,917,467 (+)Ensembl
Rnor_6.0 Ensembl656,625,650 - 56,689,238 (+)Ensembl
RefSeq Acc Id: NM_017149   ⟹   NP_058845
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8659,584,025 - 59,644,722 (+)NCBI
mRatBN7.2653,856,760 - 53,917,467 (+)NCBI
Rnor_6.0656,625,768 - 56,689,195 (+)NCBI
Rnor_5.0666,231,865 - 66,293,008 (+)NCBI
RGSC_v3.4655,895,760 - 55,957,066 (+)RGD
Celera652,995,636 - 53,056,305 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058845 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA78931 (Get FASTA)   NCBI Sequence Viewer  
  EDM03320 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000008803
  ENSRNOP00000008803.1
GenBank Protein P39020 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_058845   ⟸   NM_017149
- UniProtKB: P39020 (UniProtKB/Swiss-Prot),   G3V6T9 (UniProtKB/TrEMBL),   A6HBB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000008803   ⟸   ENSRNOT00000008803
Protein Domains
Homeobox

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P39020-F1-model_v2 AlphaFold P39020 1-303 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694564
Promoter ID:EPDNEW_R5089
Type:initiation region
Name:Meox2_1
Description:mesenchyme homeobox 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0656,625,725 - 56,625,785EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3079 AgrOrtholog
BioCyc Gene G2FUF-37782 BioCyc
Ensembl Genes ENSRNOG00000006588 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008803 ENTREZGENE
  ENSRNOT00000008803.4 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOX-1/MOX-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29279 UniProtKB/Swiss-Prot
NCBI Gene 29279 ENTREZGENE
PANTHER HOMEOBOX PROTEIN MOX-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR24328 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Meox2 PhenoGen
PRINTS HOMEOBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006588 RatGTEx
SMART HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC209311
UniProt A6HBB5 ENTREZGENE, UniProtKB/TrEMBL
  G3V6T9 ENTREZGENE, UniProtKB/TrEMBL
  MEOX2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Meox2  mesenchyme homeobox 2    mesenchyme homeo box 2  Name updated 1299863 APPROVED
2002-06-10 Meox2  mesenchyme homeo box 2      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_regulation expression is downregulated by platelet-derived growth factor (PDGF) or serum growth factors in vascular smooth muscle cells 69891