Scfd1 (sec1 family domain containing 1) - Rat Genome Database

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Gene: Scfd1 (sec1 family domain containing 1) Rattus norvegicus
Analyze
Symbol: Scfd1
Name: sec1 family domain containing 1
RGD ID: 619828
Description: Enables syntaxin binding activity. Involved in Golgi vesicle transport; regulation of ER to Golgi vesicle-mediated transport; and response to hypoxia. Located in Golgi-associated vesicle. Orthologous to human SCFD1 (sec1 family domain containing 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: RA410; rSly1; sec1 family domain-containing protein 1; Sly1; SLY1 homolog; sly1p; syntaxin-binding protein 1-like 2; vesicle transport-related; vesicle transport-related protein Ra410
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8674,531,225 - 74,609,463 (+)NCBIGRCr8
mRatBN7.2668,795,810 - 68,874,076 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl668,795,878 - 68,874,078 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx669,231,006 - 69,310,933 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0669,537,662 - 69,617,588 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0668,977,140 - 69,057,067 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0672,124,408 - 72,202,703 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,124,417 - 72,202,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0681,688,247 - 81,766,841 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4671,453,366 - 71,532,347 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1671,456,491 - 71,535,473 (+)NCBI
Celera667,685,656 - 67,762,975 (+)NCBICelera
Cytogenetic Map6q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Three-dimensional structure of the rSly1 N-terminal domain reveals a conformational change induced by binding to syntaxin 5. Arac D, etal., J Mol Biol. 2005 Feb 18;346(2):589-601. Epub 2004 Dec 24.
2. Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum to Golgi transport. Dascher C and Balch WE, J Biol Chem 1996 Jul 5;271(27):15866-9.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing. Laufman O, etal., EMBO J. 2009 Jul 22;28(14):2006-17. doi: 10.1038/emboj.2009.168. Epub 2009 Jun 18.
5. Cloning of a putative vesicle transport-related protein, RA410, from cultured rat astrocytes and its expression in ischemic rat brain. Matsuo N, etal., J Biol Chem 1997 Jun 27;272(26):16438-44.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. A mammalian homologue of SLY1, a yeast gene required for transport from endoplasmic reticulum to Golgi. Peterson MR, etal., Gene 1996 Mar 9;169(2):293-4.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics. Steegmaier M, etal., Mol Biol Cell. 2000 Aug;11(8):2719-31.
12. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Wang GL, etal., Proc Natl Acad Sci U S A 1995 Jun 6;92(12):5510-4.
13. rsly1 binding to syntaxin 5 is required for endoplasmic reticulum-to-Golgi transport but does not promote SNARE motif accessibility. Williams AL, etal., Mol Biol Cell. 2004 Jan;15(1):162-75. Epub 2003 Oct 17.
14. Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif. Yamaguchi T, etal., Dev Cell. 2002 Mar;2(3):295-305.
Additional References at PubMed
PMID:15649705   PMID:21242315   PMID:23716698   PMID:25002582  


Genomics

Comparative Map Data
Scfd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8674,531,225 - 74,609,463 (+)NCBIGRCr8
mRatBN7.2668,795,810 - 68,874,076 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl668,795,878 - 68,874,078 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx669,231,006 - 69,310,933 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0669,537,662 - 69,617,588 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0668,977,140 - 69,057,067 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0672,124,408 - 72,202,703 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,124,417 - 72,202,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0681,688,247 - 81,766,841 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4671,453,366 - 71,532,347 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1671,456,491 - 71,535,473 (+)NCBI
Celera667,685,656 - 67,762,975 (+)NCBICelera
Cytogenetic Map6q22NCBI
SCFD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381430,622,254 - 30,735,850 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1430,622,291 - 30,737,694 (+)EnsemblGRCh38hg38GRCh38
GRCh371431,091,460 - 31,205,056 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361430,161,272 - 30,274,769 (+)NCBINCBI36Build 36hg18NCBI36
Build 341430,161,271 - 30,274,769NCBI
Celera1410,957,301 - 11,070,796 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1411,209,016 - 11,322,601 (+)NCBIHuRef
CHM1_11431,090,992 - 31,204,539 (+)NCBICHM1_1
T2T-CHM13v2.01424,820,073 - 24,933,666 (+)NCBIT2T-CHM13v2.0
Scfd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391251,424,296 - 51,496,887 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1251,424,293 - 51,496,884 (+)EnsemblGRCm39 Ensembl
GRCm381251,377,513 - 51,450,104 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1251,377,510 - 51,450,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv371252,478,567 - 52,551,083 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361252,299,200 - 52,371,716 (+)NCBIMGSCv36mm8
Celera1252,670,007 - 52,746,143 (+)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1222.11NCBI
Scfd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540929,805,909 - 29,903,208 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540929,805,909 - 29,903,208 (-)NCBIChiLan1.0ChiLan1.0
SCFD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21531,953,881 - 32,060,885 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11431,170,383 - 31,277,398 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01411,401,378 - 11,508,418 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11429,602,185 - 29,709,133 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1429,602,241 - 29,709,133 (+)Ensemblpanpan1.1panPan2
SCFD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.189,970,724 - 10,077,123 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl89,970,790 - 10,077,122 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha89,897,070 - 10,003,576 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0810,071,833 - 10,178,235 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl810,071,847 - 10,178,223 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.189,750,624 - 9,856,891 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.089,831,913 - 9,938,667 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0810,108,002 - 10,214,379 (+)NCBIUU_Cfam_GSD_1.0
Scfd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864041,904,284 - 41,995,811 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364945,410,269 - 5,501,498 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364945,410,219 - 5,501,687 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCFD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl768,712,773 - 68,851,008 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1768,694,579 - 68,851,055 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2773,405,676 - 73,475,796 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Scfd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248201,614,884 - 1,714,020 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Scfd1
457 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:91
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000040548
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)66304056271636266Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat

Markers in Region
RH144427  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2668,858,370 - 68,858,527 (+)MAPPERmRatBN7.2
Rnor_6.0672,187,012 - 72,187,168NCBIRnor6.0
Rnor_5.0681,750,835 - 81,750,991UniSTSRnor5.0
RGSC_v3.4671,516,682 - 71,516,838UniSTSRGSC3.4
Celera667,747,314 - 67,747,470UniSTS
RH 3.4 Map6509.5UniSTS
Cytogenetic Map6q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000040548   ⟹   ENSRNOP00000039132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl668,795,880 - 68,874,074 (+)Ensembl
Rnor_6.0 Ensembl672,124,417 - 72,202,713 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107693   ⟹   ENSRNOP00000082071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl668,801,582 - 68,868,844 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108338   ⟹   ENSRNOP00000077399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl668,795,896 - 68,874,078 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110902   ⟹   ENSRNOP00000092379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl668,801,582 - 68,874,076 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120031   ⟹   ENSRNOP00000088329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl668,795,878 - 68,836,588 (+)Ensembl
RefSeq Acc Id: NM_019364   ⟹   NP_062237
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,531,283 - 74,609,463 (+)NCBI
mRatBN7.2668,795,885 - 68,874,076 (+)NCBI
Rnor_6.0672,124,458 - 72,202,703 (+)NCBI
Rnor_5.0681,688,247 - 81,766,841 (+)NCBI
RGSC_v3.4671,453,366 - 71,532,347 (+)RGD
Celera667,685,656 - 67,762,975 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240085   ⟹   XP_006240147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,531,225 - 74,602,812 (+)NCBI
mRatBN7.2668,795,810 - 68,866,585 (+)NCBI
Rnor_6.0672,124,408 - 72,195,203 (+)NCBI
Rnor_5.0681,688,247 - 81,766,841 (+)NCBI
Sequence:
RefSeq Acc Id: NP_062237   ⟸   NM_019364
- UniProtKB: Q62843 (UniProtKB/Swiss-Prot),   Q62991 (UniProtKB/Swiss-Prot),   A6HBG9 (UniProtKB/TrEMBL),   A0A8I6AGF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240147   ⟸   XM_006240085
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y1I7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039132   ⟸   ENSRNOT00000040548
Ensembl Acc Id: ENSRNOP00000092379   ⟸   ENSRNOT00000110902
Ensembl Acc Id: ENSRNOP00000077399   ⟸   ENSRNOT00000108338
Ensembl Acc Id: ENSRNOP00000082071   ⟸   ENSRNOT00000107693
Ensembl Acc Id: ENSRNOP00000088329   ⟸   ENSRNOT00000120031

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62991-F1-model_v2 AlphaFold Q62991 1-637 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694583
Promoter ID:EPDNEW_R5108
Type:initiation region
Name:Scfd1_1
Description:sec1 family domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0672,124,466 - 72,124,526EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619828 AgrOrtholog
BioCyc Gene G2FUF-37596 BioCyc
Ensembl Genes ENSRNOG00000031203 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055016621 UniProtKB/Swiss-Prot
  ENSRNOG00060016249 UniProtKB/Swiss-Prot
  ENSRNOG00065003045 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000040548.3 UniProtKB/Swiss-Prot
  ENSRNOT00000107693.1 UniProtKB/TrEMBL
  ENSRNOT00000108338.1 UniProtKB/TrEMBL
  ENSRNOT00000110902.1 UniProtKB/TrEMBL
  ENSRNOT00000120031.1 UniProtKB/TrEMBL
  ENSRNOT00055028274 UniProtKB/Swiss-Prot
  ENSRNOT00060027880 UniProtKB/Swiss-Prot
  ENSRNOT00065004284 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.1910 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.2060 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Sec-1-like_dom1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec-1-like_dom2 UniProtKB/Swiss-Prot
  Sec-1-like_dom3a UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec1-like_dom2 UniProtKB/TrEMBL
  Sec1-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:54350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 54350 ENTREZGENE
PANTHER PTHR11679 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sec1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Scfd1 PhenoGen
PIRSF VPS45_Sec1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000031203 RatGTEx
  ENSRNOG00055016621 RatGTEx
  ENSRNOG00060016249 RatGTEx
  ENSRNOG00065003045 RatGTEx
Superfamily-SCOP SSF56815 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y1I7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A9S9_RAT UniProtKB/TrEMBL
  A0A8I6AGF5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G6Y5_RAT UniProtKB/TrEMBL
  A6HBG9 ENTREZGENE, UniProtKB/TrEMBL
  A6HBH0_RAT UniProtKB/TrEMBL
  Q62843 ENTREZGENE
  Q62991 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q62843 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Scfd1  sec1 family domain containing 1  RA410  vesicle transport-related  Symbol and Name updated 1299863 APPROVED
2002-08-07 RA410  vesicle transport-related      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation mRNA induced by a period of hypoxia followed by reoxygenation 633771