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Gene: Gen1 (GEN1 Holliday junction 5' flap endonuclease) Rattus norvegicus

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Symbol:

Gen1

Name:

GEN1 Holliday junction 5' flap endonuclease

RGD ID:

1559792

Description:

Predicted to enable several functions, including DNA endonuclease activity; magnesium ion binding activity; and protein homodimerization activity. Predicted to be involved in DNA metabolic process and regulation of cell cycle process. Predicted to be located in centrosome. Orthologous to human GEN1 (GEN1 Holliday junction 5' flap endonuclease); INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

flap endonuclease GEN homolog 1; Gen endonuclease homolog 1; Gen endonuclease homolog 1 (Drosophila); Gen homolog 1, endonuclease; Gen homolog 1, endonuclease (Drosophila); LOC298884; RGD1559792; similar to RIKEN cDNA 5830483C08 gene

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	39,666,675 - 39,697,480 (-)	NCBI		GRCr8
mRatBN7.2	6	33,947,599 - 33,978,461 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	33,948,206 - 33,978,401 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	34,241,173 - 34,270,971 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	34,557,114 - 34,586,912 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	34,027,879 - 34,057,691 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	36,910,064 - 36,940,868 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	36,910,675 - 36,940,868 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	46,660,177 - 46,690,981 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	34,679,618 - 34,709,812 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	33,348,660 - 33,378,853 (-)	NCBI		Celera
Cytogenetic Map	6	q15	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Breast Neoplasms (ISO)

Hereditary Neoplastic Syndromes (ISO)

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP,ISO)

2,2'-Methylenebis(4-methyl-6-tert-butylphenol) (ISO)

2-butoxyethanol (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

alpha-Zearalanol (EXP)

avobenzone (ISO)

azoxystrobin (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

butanal (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

doxorubicin (ISO)

FR900359 (ISO)

GSK-J4 (ISO)

hydroxyurea (ISO)

leflunomide (ISO)

lidocaine (EXP)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

ochratoxin A (EXP)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

picoxystrobin (ISO)

potassium dichromate (ISO)

resveratrol (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

double-strand break repair via homologous recombination (ISO)

positive regulation of mitotic cell cycle spindle assembly checkpoint (ISO)

regulation of centrosome duplication (ISO)

replication fork processing (ISO)

resolution of DNA recombination intermediates (ISO)

resolution of mitotic recombination intermediates (ISO)

Cellular Component

centrosome (ISO)

Molecular Function

5'-flap endonuclease activity (IBA,ISO)

catalytic activity (IEA)

crossover junction DNA endonuclease activity (ISO)

DNA binding (IEA)

four-way junction DNA binding (IBA,ISO)

hydrolase activity (IEA)

magnesium ion binding (ISO)

metal ion binding (IEA)

nuclease activity (IEA)

protein homodimerization activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:23108668	PMID:23166748	PMID:23376485	PMID:24080495	PMID:26578604	PMID:26682650	PMID:28049850

Genomics

Comparative Map Data

Gen1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	39,666,675 - 39,697,480 (-)	NCBI		GRCr8
mRatBN7.2	6	33,947,599 - 33,978,461 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	33,948,206 - 33,978,401 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	34,241,173 - 34,270,971 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	34,557,114 - 34,586,912 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	34,027,879 - 34,057,691 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	36,910,064 - 36,940,868 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	36,910,675 - 36,940,868 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	46,660,177 - 46,690,981 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	34,679,618 - 34,709,812 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	33,348,660 - 33,378,853 (-)	NCBI		Celera
Cytogenetic Map	6	q15	NCBI

GEN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	17,753,278 - 17,788,946 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	17,753,858 - 17,788,946 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	17,935,136 - 17,970,213 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	17,798,658 - 17,826,911 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	17,815,464 - 17,846,898 (+)	NCBI		Celera
Cytogenetic Map	2	p24.2	NCBI
HuRef	2	17,710,243 - 17,741,677 (+)	NCBI		HuRef
CHM1_1	2	17,864,556 - 17,895,909 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	17,785,078 - 17,820,679 (+)	NCBI		T2T-CHM13v2.0

Gen1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	11,288,929 - 11,316,030 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	11,288,921 - 11,315,802 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	11,238,928 - 11,266,029 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	11,238,920 - 11,265,801 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	11,247,732 - 11,272,593 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	11,266,084 - 11,292,109 (-)	NCBI		MGSCv36	mm8
Celera	12	11,585,054 - 11,610,024 (-)	NCBI		Celera
Cytogenetic Map	12	A1.1	NCBI
cM Map	12	5.58	NCBI

Gen1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955469	552,677 - 592,137 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955469	552,850 - 590,792 (+)	NCBI	ChiLan1.0	ChiLan1.0

GEN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	108,744,371 - 108,775,128 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	108,750,934 - 108,779,084 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	17,735,953 - 17,766,018 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	17,861,948 - 17,892,048 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	17,862,070 - 17,892,048 (+)	Ensembl	panpan1.1		panPan2

GEN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	13,201,540 - 13,233,028 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	13,201,777 - 13,232,120 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	13,153,314 - 13,184,106 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	13,338,011 - 13,368,882 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	13,338,028 - 13,370,672 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	13,196,289 - 13,227,013 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	13,207,483 - 13,238,260 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	13,233,389 - 13,264,461 (+)	NCBI		UU_Cfam_GSD_1.0

Gen1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	57,656,411 - 57,682,518 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936493	13,157,119 - 13,177,525 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936493	13,157,114 - 13,182,797 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GEN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	120,065,973 - 120,097,056 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	120,067,792 - 120,097,305 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	128,215,665 - 128,244,806 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GEN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	89,886,102 - 89,917,485 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	89,888,853 - 89,911,293 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	22,296,831 - 22,332,300 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gen1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	696,080 - 718,240 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624738	689,835 - 718,549 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gen1
275 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	192
Count of miRNA genes:	135
Interacting mature miRNAs:	163
Transcripts:	ENSRNOT00000006470
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1	41223769	Rat
634318	Bw118	Body weight QTL 118	3.55		abdominal fat pad mass (VT:1000711)	abdominal fat pad weight (CMO:0000088)	6	33309549	57730294	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	14368788	59368788	Rat
1331743	Uae28	Urinary albumin excretion QTL 28	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	1	34235784	Rat
2292589	Emca10	Estrogen-induced mammary cancer QTL 10		0.048	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	16536140	61536140	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	14368788	59368788	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	54641141	Rat
1331779	Rf38	Renal function QTL 38	2.876		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	32074428	72227641	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1	41223769	Rat
1578758	Tcas9	Tongue tumor susceptibility QTL 9	3.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	6	1	37618905	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	41223769	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	39036266	Rat
738024	Sach5	Saccharine consumption QTL 5	3.9	0.00039	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	6	1	43394190	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1	41223769	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1	41223769	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	15107216	107351382	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	1	42487980	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	1	42487980	Rat
7411584	Foco4	Food consumption QTL 4	4.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	42838846	Rat
1578665	Bss16	Bone structure and strength QTL 16	4.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	6	11735669	72593685	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	34434305	Rat
1641898	Colcr4	Colorectal carcinoma resistance QTL4	3.71	0.0007	intestine integrity trait (VT:0010554)	well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)	6	20338777	62613667	Rat
1578668	Bmd14	Bone mineral density QTL 14	3.8		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	11735669	72593685	Rat
6893340	Cm77	Cardiac mass QTL 77	0.26	0.57	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	33309549	81132889	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	72227641	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	1	42487980	Rat
1354664	Slep2	Serum leptin concentration QTL 2	4.49		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	6	16536140	71636405	Rat

Markers in Region

RH143724

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	33,977,895 - 33,978,065 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	36,940,363 - 36,940,532	NCBI	Rnor6.0
Rnor_5.0	6	46,690,476 - 46,690,645	UniSTS	Rnor5.0
RGSC_v3.4	6	34,709,307 - 34,709,476	UniSTS	RGSC3.4
Celera	6	33,378,348 - 33,378,517	UniSTS
RH 3.4 Map	6	145.4	UniSTS
Cytogenetic Map	6	q14	UniSTS

BF387143

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	33,979,868 - 33,980,064 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	36,942,336 - 36,942,531	NCBI	Rnor6.0
Rnor_5.0	6	46,692,449 - 46,692,644	UniSTS	Rnor5.0
RGSC_v3.4	6	34,711,280 - 34,711,475	UniSTS	RGSC3.4
Celera	6	33,380,321 - 33,380,516	UniSTS
Cytogenetic Map	6	q14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001434077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039111945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005505464	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005505465	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010052061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006470 ⟹ ENSRNOP00000006470

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	33,948,206 - 33,978,401 (-)	Ensembl
Rnor_6.0 Ensembl	6	36,910,675 - 36,940,868 (-)	Ensembl

RefSeq Acc Id:

NM_001106717 ⟹ NP_001100187

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	39,667,286 - 39,697,480 (-)	NCBI
mRatBN7.2	6	33,948,206 - 33,978,401 (-)	NCBI
Rnor_6.0	6	36,910,675 - 36,940,868 (-)	NCBI
Rnor_5.0	6	46,660,177 - 46,690,981 (-)	NCBI
RGSC_v3.4	6	34,679,618 - 34,709,812 (-)	RGD
Celera	6	33,348,660 - 33,378,853 (-)	RGD

Sequence:

show sequence

TGGCGATGGCGCTGGATTCGAACTGCTGCCGGGAGCTTAGTGCTTGGGAGTGCTGTGAGAGGCT
TCCCCGCCCTTTGGTCTTGTTTGTTTGTTTGTTTTAACTTTGGTTTGAGGGAATTCGGGAACTT
AGGGGCAGCGATAGTTATTAGACTCCTGGCGGCCAGATTGGTACATGACAGAAGTGTTCCTTCC
ACAGCCTCGAAGAGGGGGTGTCTGGATAACACCAGATAATCAACCATCAGGATGGGAGTGAATG
ACCTGTGGCAAATTTTGGAGCCTGTAAAGCAACATATCCACTTGCAGGATCTTTGTGGGAAGAC
CATTGCCGTTGATTTGAGTCTCTGGGTATGCGAGGCACAGACAGTGAAGAAAATGATTGGAACT
GTCATGAAGCCCCACCTCAGGAACCTATTTTTTCGTATTTCATATTTAACTCAAATGAATGTAA
AACTGGTGTTTGTGATGGAAGGGGAGCCACCAAAGCTGAAAGCTGATGTCATGAACAAGAGGAC
TCAGACTCGATACGGGCCTTCTGGAAAATCGAGGTCTCAGAAAACAGGGAGATCGCATTTTAAG
TCAGTCTTACGAGAGTGCCTTGAAATGCTAGAGTGCCTAGGAATGCCCTGGGTCCAGGCTGCGG
GGGAAGCTGAGGCCATGTGTGCTTACCTTAATGCCAGCGGCCATGTGGACGGCTGCCTCACCAA
CGACGGCGATGCTTTCCTTTATGGAGCCCAGACTGTGTACAGGAATTTCACCATGAACACAAAG
GATCCACATGTTGACTGTTACACGGTATCATCTATCAAGAGTAAGCTAGGCTTGGATCGAGATG
CTCTGGTGGGACTGGCGGTACTTCTTGGTTGTGATTACCTTCCGAAGGGAGTGCCTGGAGTTGG
AAAAGAACAAGCGTTAAAACTTTTGCAGATTTTGAAAGGTCAAAGTTTGCTTCAGAGGTTTAAC
CAGTGGACTGAAGAACCTGGCTACTCTGTTCCACAATCAGCAGCAAAAAAAGTGGTTCACTGCT
CGGTGTGTTCCCATCCAGGTTCTCCTAAGGATCATGAACGCAATGGGTGCACACTATGTAAAAG
TGATAGATACTGTGAACCACATGATTATGAATACCTCTGTCCTTGTGAATGGCACCAGACAGAC
CATAATAGGCAACTAAATGAAATAGAAAACAATATTAAAAAGAAAGCTTGCAGTTGCGAAGGAT
TTCCATTCCATGAGGTCATCCAAGAATTCCTTTCGAATAAGAATAAACTGTTAAAACCGATCAG
GTACCAAAGACCTGATTTATTATTGTTTCAGAGATTTACTGTTCAAAAAATGGAGTGGCCCAGT
CACTATGCGTGTGAAAAATTGTTGGTGCTTTTGACCCGCTATGACATGATAGAAAGAAAACTTG
GTAGAAAGACTTCCAATCAACTACAGCCAATTAGAATTGTTAAACCTCGAATCAGAAATGGAGT
CTGTTGTCTTGAAATAGAATGGGAAAAGCCTGAACATTATTCGGTAGAAGATACACAACCTGGA
GGACTGGATCTCCTTACAATCGAAGAAGCATCACTGTTTGAAGCAGCCTATCCTGAAGTTGTAG
CTATCTACCAGAAACAACAGTCAGAAACTAAAGGGAAGAAACAGAAAAATATAAAAATTAAGCC
CAAAGGAAGCCATCTACCAGAATCAGATGATGTGATCAGTTCCCAGTCACTTATTACTTTAGAA
CCTATATCAAAAGCCTTCCCCAAGCAGAATCCCAAATTTGATTTGGAAATTTCTCCAGATCCTA
TTTTAGCACAGGAGTCTACTTCTCCCTCATTGAGTAGTTTTGTTTCCCCTGAAAATGCTCTTGG
TTTGAATTTGCAAGAACAGTTAATGCCTTCTCCAAGAACTTTGGCTGTAAAGCAAACTAAAGAT
GTCAGTAATTTTCTAGTTTCAGAGTGTAGTCAGCCCAGTTCTTCATCCCATAATATTTCTGTGA
TTACTGATCTACACTTGAGTACCATTGACTGGGCAGGTACTTCTTTTAGTAATTCTCCAGCAGT
TCAAAGAAACACTTTCTCTCAAGATTTACAATCAGAACCTGAATCATCAGCCATCCTTCCTGCC
TTTGAACAGTTGTCATATGAATCAGAACAATGTACCTTAAGCAACAAAGTGTCCAATAGAGGTC
TTCAGAAGAGTGGTCCTGAAGAGCATCTCCTTTCCAGCATCACTGGTTTACATCTTCACGATTT
GCCTCTAAAGGAAAGAATACATATAAAATCTTCATGCCCTCAGTATAATGTAGGAGCAGATGCT
GACCTGGAAAGTTTACCCCTAACAATGAATCACTCTTGCATTGCTTACAGTAGCTCTGGTGGTT
CATCCCATTTTTCGAAGGATCTTACAGGGGTATATCTTCAGAAAGAGCTCAGAAACTCTAAAGT
TCTAGACAGCCACTTCCTTCAAGAAAACTTCAGGGTGAATACTTCCTTACCTTATTCTTTCAAT
GACGAAGCAGTAAAGACTTCCAGTCTTCAAGTTGGGCTGCCAACTGCTGCTGTACCTCATAATC
CAAAAGTTGATGTGAAAACTAAGAACCTTGTCAAGAAGAGTAGTGTTTGCCTCAAGAGAGATTC
CTCAGATGAAGAGAATGCTGCAGTGTCCTGGAAAGCTAAGTATACTGCTCCTAAATTGAAACAC
AGCTCTCATAATCATAGCCTAGTCCATGACAGAGACAGTACTCACAACAAACACAGAAATCCGA
AAGATGAATCTAACGAAACCAAACTGTGTACTGAGTCTTTTAAAATAGCTGAAGATGAAGAAAA
CAAGTTCTCAGATCCAGCAAGAAATCCCCAGAGTTTTCTACAATGTCATAACAAGGATGAGGAC
TCTGCTGACTGCTGGGAAAGTCCTCTCCCTTTACGCCAGAGGTTAAAGCTCAGGTTCCAGAACA
CTCAAAGTAGACTTTATAATACTTAAATTTAATGTGTGTAAATGCTGGTAACATGAGCAGAAGC
CAAGCAAACTTGGGTTTGGTAGAAAATGTACATGACTATGTGCCATTTAAATCAAAATTGTAAT
TTTAAAATGTTAACAGCTAGGTGTGGCTCATGCCTATAATCACAGCATGTCTGAGGTTAAAAGA
GTCCAGAGGATCATGCACCAGGAGTTCAAAGTCATCTTCTGGTATATGGAGATTGTCAGACCAA
TCTCAGTTATCTAAGAAAGGAAAAAAATTAAAATTTTGACTATAAAAGATGAGCCTCTGGTGAC
AACTTGAAATGGTTTTTTTTTTTAGAACATTTGAATGTCTTCTTGAGGTATCTTTATATTATCT
AGCTTTAACATATTATTTCTTGACAAAGTAAATGCTTTATCATTTTTTGTTCATCTTATGTTAG
GGTCTAAAGCAACTGTTTACTGTCTAGCCATCCTCAAGATGGTAACACTTTATAATGGTGTTGC
AGTATCTTTTATGACCCTTCCTAATGGCTGTATTTCCCCTTCATGTTAAAGAACCATTAGCATG
CTCTTCCACTTTTAGTAATGTCATGTTTGAGGAGTGAAAATGGAAGAGGATGTGTAGTGAAGTG
TGATTGTGAAGTCTTGGTAAGGAAAGTTACCTTATATACATTCAGAAGTTCACAGGCACTGTAA
GCAGGAAATATTTTAAATCAGATGTAAACCAAAAGAGAATTGGAAGCTTCCTCAGGATCACACA
GTAATAATAGTAATGGTGTGGATCCCATCTTTCCAGTTTGGTTCTTGTGATTTTATTTTTCTGT
TTTGTTTGTAATCTATAGAACTGTTCCCTTTTGTCTTAAATTTTAGTTTGCATGTAATGTTGAC
TTTAATTCCTATAAGTCTTAAATCTTACATAAATTGTAAAAATCCTAAAGGCATGTAGAGTTAC
AGCTGTTTGTATGTGACTGGAGCCTGAAAGTAGAGGATCCTAAGGAATCCATCAAAAACGTATT
AAAAGCAAGCCAGGCTTGGTGACACACTTCTTTAATGCCAGCATTTGGAAGGCAGAGGTAAGTG
GATCTCTAAATTCAAGACTAGCCTGGTAGGCAGAGTTAGTTCCAGGACAGCCAGGGCTACACAG
AATTCCTGTTTTGAAAAAACAAAAAAAAAATTTTTTAAACCAAAATAAAAACTATTAAAAGTGA
AGAGTAAGTTTGCAAGGTTGCAAAATTCAAAAAATAGTTTACTAACTACATAGTTGTAGTTCTG
TATATTCAGTGTATGACTGAAATTTAACCAAGAAGATTAAAGTTACTCTGTTTACAACATG

hide sequence

RefSeq Acc Id:

XM_006239896 ⟹ XP_006239958

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	39,666,675 - 39,697,402 (-)	NCBI
mRatBN7.2	6	33,947,599 - 33,978,461 (-)	NCBI
Rnor_6.0	6	36,910,064 - 36,940,738 (-)	NCBI
Rnor_5.0	6	46,660,177 - 46,690,981 (-)	NCBI

Sequence:

show sequence

GGGCAGCGATAGTTATTAGACTCCTGGCGGCCAGATTGGTACATGACAGAAGTGTTCCTTCCAC
AGCCTCGAAGAGGGGGTGTCTGGCTGTTTGCCTGCTTCCGTGATTCCTTGCTTAAGTGTACTTC
AGATAACACCAGATAATCAACCATCAGGATGGGAGTGAATGACCTGTGGCAAATTTTGGAGCCT
GTAAAGCAACATATCCACTTGCAGGATCTTTGTGGGAAGACCATTGCCGTTGATTTGAGTCTCT
GGGTATGCGAGGCACAGACAGTGAAGAAAATGATTGGAACTGTCATGAAGCCCCACCTCAGGAA
CCTATTTTTTCGTATTTCATATTTAACTCAAATGAATGTAAAACTGGTGTTTGTGATGGAAGGG
GAGCCACCAAAGCTGAAAGCTGATGTCATGAACAAGAGGACTCAGACTCGATACGGGCCTTCTG
GAAAATCGAGGTCTCAGAAAACAGGGAGATCGCATTTTAAGTCAGTCTTACGAGAGTGCCTTGA
AATGCTAGAGTGCCTAGGAATGCCCTGGGTCCAGGCTGCGGGGGAAGCTGAGGCCATGTGTGCT
TACCTTAATGCCAGCGGCCATGTGGACGGCTGCCTCACCAACGACGGCGATGCTTTCCTTTATG
GAGCCCAGACTGTGTACAGGAATTTCACCATGAACACAAAGGATCCACATGTTGACTGTTACAC
GGTATCATCTATCAAGAGTAAGCTAGGCTTGGATCGAGATGCTCTGGTGGGACTGGCGGTACTT
CTTGGTTGTGATTACCTTCCGAAGGGAGTGCCTGGAGTTGGAAAAGAACAAGCGTTAAAACTTT
TGCAGATTTTGAAAGGTCAAAGTTTGCTTCAGAGGTTTAACCAGTGGACTGAAGAACCTGGCTA
CTCTGTTCCACAATCAGCAGCAAAAAAAGTGGTTCACTGCTCGGTGTGTTCCCATCCAGGTTCT
CCTAAGGATCATGAACGCAATGGGTGCACACTATGTAAAAGTGATAGATACTGTGAACCACATG
ATTATGAATACCTCTGTCCTTGTGAATGGCACCAGACAGACCATAATAGGCAACTAAATGAAAT
AGAAAACAATATTAAAAAGAAAGCTTGCAGTTGCGAAGGATTTCCATTCCATGAGGTCATCCAA
GAATTCCTTTCGAATAAGAATAAACTGTTAAAACCGATCAGGTACCAAAGACCTGATTTATTAT
TGTTTCAGAGATTTACTGTTCAAAAAATGGAGTGGCCCAGTCACTATGCGTGTGAAAAATTGTT
GGTGCTTTTGACCCGCTATGACATGATAGAAAGAAAACTTGGTAGAAAGACTTCCAATCAACTA
CAGCCAATTAGAATTGTTAAACCTCGAATCAGAAATGGAGTCTGTTGTCTTGAAATAGAATGGG
AAAAGCCTGAACATTATTCGGTAGAAGATACACAACCTGGAGGACTGGATCTCCTTACAATCGA
AGAAGCATCACTGTTTGAAGCAGCCTATCCTGAAGTTGTAGCTATCTACCAGAAACAACAGTCA
GAAACTAAAGGGAAGAAACAGAAAAGTAAGGATATAAAAATTAAGCCCAAAGGAAGCCATCTAC
CAGAATCAGATGATGTGATCAGTTCCCAGTCACTTATTACTTTAGAACCTATATCAAAAGCCTT
CCCCAAGCAGAATCCCAAATTTGATTTGGAAATTTCTCCAGATCCTATTTTAGCACAGGAGTCT
ACTTCTCCCTCATTGAGTAGTTTTGTTTCCCCTGAAAATGCTCTTGGTTTGAATTTGCAAGAAC
AGTTAATGCCTTCTCCAAGAACTTTGGCTGTAAAGCAAACTAAAGATGTCAGTAATTTTCTAGT
TTCAGAGTGTAGTCAGCCCAGTTCTTCATCCCATAATATTTCTGTGATTACTGATCTACACTTG
AGTACCATTGACTGGGCAGGTACTTCTTTTAGTAATTCTCCAGCAGTTCAAAGAAACACTTTCT
CTCAAGATTTACAATCAGAACCTGAATCATCAGCCATCCTTCCTGCCTTTGAACAGTTGTCATA
TGAATCAGAACAATGTACCTTAAGCAACAAAGTGTCCAATAGAGGTCTTCAGAAGAGTGGTCCT
GAAGAGCATCTCCTTTCCAGCATCACTGGTTTACATCTTCACGATTTGCCTCTAAAGGAAAGAA
TACATATAAAATCTTCATGCCCTCAGTATAATGTAGGAGCAGATGCTGACCTGGAAAGTTTACC
CCTAACAATGAATCACTCTTGCATTGCTTACAGTAGCTCTGGTGGTTCATCCCATTTTTCGAAG
GATCTTACAGGGGTATATCTTCAGAAAGAGCTCAGAAACTCTAAAGTTCTAGACAGCCACTTCC
TTCAAGAAAACTTCAGGGTGAATACTTCCTTACCTTATTCTTTCAATGACGAAGCAGTAAAGAC
TTCCAGTCTTCAAGTTGGGCTGCCAACTGCTGCTGTACCTCATAATCCAAAAGTTGATGTGAAA
ACTAAGAACCTTGTCAAGAAGAGTAGTGTTTGCCTCAAGAGAGATTCCTCAGATGAAGAGAATG
CTGCAGTGTCCTGGAAAGCTAAGTATACTGCTCCTAAATTGAAACACAGCTCTCATAATCATAG
CCTAGTCCATGACAGAGACAGTACTCACAACAAACACAGAAATCCGAAAGATGAATCTAACGAA
ACCAAACTGTGTACTGAGTCTTTTAAAATAGCTGAAGATGAAGAAAACAAGTTCTCAGATCCAG
CAAGAAATCCCCAGAGTTTTCTACAATGTCATAACAAGGATGAGGACTCTGCTGACTGCTGGGA
AAGTCCTCTCCCTTTACGCCAGAGGTTAAAGCTCAGGTTCCAGAACACTCAAAGTAGACTTTAT
AATACTTAAATTTAATGTGTGTAAATGCTGGTAACATGAGCAGAAGCCAAGCAAACTTGGGTTT
GGTAGAAAATGTACATGACTATGTGCCATTTAAATCAAAATTGTAATTTTAAAATGTTAACAGC
TAGGTGTGGCTCATGCCTATAATCACAGCATGTCTGAGGTTAAAAGAGTCCAGAGGATCATGCA
CCAGGAGTTCAAAGTCATCTTCTGGTATATGGAGATTGTCAGACCAATCTCAGTTATCTAAGAA
AGGAAAAAAATTAAAATTTTGACTATAAAAGATGAGCCTCTGGTGACAACTTGAAATGGTTTTT
TTTTTTAGAACATTTGAATGTCTTCTTGAGGTATCTTTATATTATCTAGCTTTAACATATTATT
TCTTGACAAAGTAAATGCTTTATCATTTTTTGTTCATCTTATGTTAGGGTCTAAAGCAACTGTT
TACTGTCTAGCCATCCTCAAGATGGTAACACTTTATAATGGTGTTGCAGTATCTTTTATGACCC
TTCCTAATGGCTGTATTTCCCCTTCATGTTAAAGAACCATTAGCATGCTCTTCCACTTTTAGTA
ATGTCATGTTTGAGGAGTGAAAATGGAAGAGGATGTGTAGTGAAGTGTGATTGTGAAGTCTTGG
TAAGGAAAGTTACCTTATATACATTCAGAAGTTCACAGGCACTGTAAGCAGGAAATATTTTAAA
TCAGATGTAAACCAAAAGAGAATTGGAAGCTTCCTCAGGATCACACAGTAATAATAGTAATGGT
GTGGATCCCATCTTTCCAGTTTGGTTCTTGTGATTTTATTTTTCTGTTTTGTTTGTAATCTATA
GAACTGTTCCCTTTTGTCTTAAATTTTAGTTTGCATGTAATGTTGACTTTAATTCCTATAAGTC
TTAAATCTTACATAAATTGTAAAAATCCTAAAGGCATGTAGAGTTACAGCTGTTTGTATGTGAC
TGGAGCCTGAAAGTAGAGGATCCTAAGGAATCCATCAAAAACGTATTAAAAGCAAGCCAGGCTT
GGTGACACACTTCTTTAATGCCAGCATTTGGAAGGCAGAGGTAAGTGGATCTCTAAATTCAAGA
CTAGCCTGGTAGGCAGAGTTAGTTCCAGGACAGCCAGGGCTACACAGAATTCCTGTTTTGAAAA
AACAAAAAAAAAATTTTTTAAACCAAAATAAAAACTATTAAAAGTGAAGAGTAAGTTTGCAAGG
TTGCAAAATTCAAAAAATAGTTTACTAACTACATAGTTGTAGTTCTGTATATTCAGTGTATGAC
TGAAATTTAACCAAGAAGATTAAAGTTACTCTGTTTACAACATGAAGAAAATGAACACATTGAA
CATGACAAAATTAGTGACCATTGAAAAACAATGGACAAAATGAAAGTGTAAATAAAAAGAGACA
TTGCAGATCGTGGCTCAGAAGACTTACCTTGGTGGTACTGTTAGACTGTTGCATTTACTTGCCA
GCACTTGGGAGGAAGAGTTGGATACCAGCCTGCTCTACAGAGCAAGTTCCAGGACAGCCAAGGC
TACACAGAAAAACCCTGTCTGGAAAAACTAACCAATGAAGAGGAAGATAAACAACTGTTTGGTT
TCAATCCAATCCCATCGATCTCATGTCTGTTTGCTCCTCTCCCCACCCCCAGAACATGGCAAGC
TGATTTCATTATTCAGATAGAAATTTAACAAAATAGCACTTCTTGGGACAATTGGAGAATTCAC
CCTTCCTGATTCCTGATTACTACAAAGCTGTTTAACTTAAATATTTTATACTGATATAAGGGTA
GGTGTGTAGATAAATGCTAAATCAGTTGGACAGAATTGAGTCTAGAAATATGCCCTCACATTAT
GGTCAGTTGAATTTTTAGCCAGTATGAAGACAATTCAGTGGGGAAACAAGTCTCAATAAATGCT
TCTGGAATTTTTGGC

hide sequence

RefSeq Acc Id:

XM_039111944 ⟹ XP_038967872

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	39,666,675 - 39,697,402 (-)	NCBI
mRatBN7.2	6	33,947,599 - 33,978,461 (-)	NCBI

RefSeq Acc Id:

XM_039111945 ⟹ XP_038967873

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	39,670,552 - 39,697,402 (-)	NCBI
mRatBN7.2	6	33,951,473 - 33,978,461 (-)	NCBI

RefSeq Acc Id:

XM_063261649 ⟹ XP_063117719

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	39,666,675 - 39,677,060 (-)	NCBI

RefSeq Acc Id:

XR_005505464

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	39,669,788 - 39,697,402 (-)	NCBI
mRatBN7.2	6	33,950,709 - 33,978,461 (-)	NCBI

RefSeq Acc Id:

XR_005505465

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	39,670,552 - 39,697,402 (-)	NCBI
mRatBN7.2	6	33,951,547 - 33,978,461 (-)	NCBI

RefSeq Acc Id:

XR_010052061

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	39,669,785 - 39,697,402 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100187	(Get FASTA)	NCBI Sequence Viewer
	NP_001421006	(Get FASTA)	NCBI Sequence Viewer
	XP_006239958	(Get FASTA)	NCBI Sequence Viewer
	XP_038967872	(Get FASTA)	NCBI Sequence Viewer
	XP_038967873	(Get FASTA)	NCBI Sequence Viewer
	XP_063117719	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM03099	(Get FASTA)	NCBI Sequence Viewer
	EDM03100	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006470.4

RefSeq Acc Id:

NP_001100187 ⟸ NM_001106717

- Sequence:

show sequence

MGVNDLWQILEPVKQHIHLQDLCGKTIAVDLSLWVCEAQTVKKMIGTVMKPHLRNLFFRISYLT
QMNVKLVFVMEGEPPKLKADVMNKRTQTRYGPSGKSRSQKTGRSHFKSVLRECLEMLECLGMPW
VQAAGEAEAMCAYLNASGHVDGCLTNDGDAFLYGAQTVYRNFTMNTKDPHVDCYTVSSIKSKLG
LDRDALVGLAVLLGCDYLPKGVPGVGKEQALKLLQILKGQSLLQRFNQWTEEPGYSVPQSAAKK
VVHCSVCSHPGSPKDHERNGCTLCKSDRYCEPHDYEYLCPCEWHQTDHNRQLNEIENNIKKKAC
SCEGFPFHEVIQEFLSNKNKLLKPIRYQRPDLLLFQRFTVQKMEWPSHYACEKLLVLLTRYDMI
ERKLGRKTSNQLQPIRIVKPRIRNGVCCLEIEWEKPEHYSVEDTQPGGLDLLTIEEASLFEAAY
PEVVAIYQKQQSETKGKKQKNIKIKPKGSHLPESDDVISSQSLITLEPISKAFPKQNPKFDLEI
SPDPILAQESTSPSLSSFVSPENALGLNLQEQLMPSPRTLAVKQTKDVSNFLVSECSQPSSSSH
NISVITDLHLSTIDWAGTSFSNSPAVQRNTFSQDLQSEPESSAILPAFEQLSYESEQCTLSNKV
SNRGLQKSGPEEHLLSSITGLHLHDLPLKERIHIKSSCPQYNVGADADLESLPLTMNHSCIAYS
SSGGSSHFSKDLTGVYLQKELRNSKVLDSHFLQENFRVNTSLPYSFNDEAVKTSSLQVGLPTAA
VPHNPKVDVKTKNLVKKSSVCLKRDSSDEENAAVSWKAKYTAPKLKHSSHNHSLVHDRDSTHNK
HRNPKDESNETKLCTESFKIAEDEENKFSDPARNPQSFLQCHNKDEDSADCWESPLPLRQRLKL
RFQNTQSRLYNT

hide sequence

RefSeq Acc Id:

XP_006239958 ⟸ XM_006239896

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGVNDLWQILEPVKQHIHLQDLCGKTIAVDLSLWVCEAQTVKKMIGTVMKPHLRNLFFRISYLT
QMNVKLVFVMEGEPPKLKADVMNKRTQTRYGPSGKSRSQKTGRSHFKSVLRECLEMLECLGMPW
VQAAGEAEAMCAYLNASGHVDGCLTNDGDAFLYGAQTVYRNFTMNTKDPHVDCYTVSSIKSKLG
LDRDALVGLAVLLGCDYLPKGVPGVGKEQALKLLQILKGQSLLQRFNQWTEEPGYSVPQSAAKK
VVHCSVCSHPGSPKDHERNGCTLCKSDRYCEPHDYEYLCPCEWHQTDHNRQLNEIENNIKKKAC
SCEGFPFHEVIQEFLSNKNKLLKPIRYQRPDLLLFQRFTVQKMEWPSHYACEKLLVLLTRYDMI
ERKLGRKTSNQLQPIRIVKPRIRNGVCCLEIEWEKPEHYSVEDTQPGGLDLLTIEEASLFEAAY
PEVVAIYQKQQSETKGKKQKSKDIKIKPKGSHLPESDDVISSQSLITLEPISKAFPKQNPKFDL
EISPDPILAQESTSPSLSSFVSPENALGLNLQEQLMPSPRTLAVKQTKDVSNFLVSECSQPSSS
SHNISVITDLHLSTIDWAGTSFSNSPAVQRNTFSQDLQSEPESSAILPAFEQLSYESEQCTLSN
KVSNRGLQKSGPEEHLLSSITGLHLHDLPLKERIHIKSSCPQYNVGADADLESLPLTMNHSCIA
YSSSGGSSHFSKDLTGVYLQKELRNSKVLDSHFLQENFRVNTSLPYSFNDEAVKTSSLQVGLPT
AAVPHNPKVDVKTKNLVKKSSVCLKRDSSDEENAAVSWKAKYTAPKLKHSSHNHSLVHDRDSTH
NKHRNPKDESNETKLCTESFKIAEDEENKFSDPARNPQSFLQCHNKDEDSADCWESPLPLRQRL
KLRFQNTQSRLYNT

hide sequence

Ensembl Acc Id:

ENSRNOP00000006470 ⟸ ENSRNOT00000006470

RefSeq Acc Id:	XP_038967872 ⟸ XM_039111944
- Peptide Label:	isoform X2
- UniProtKB:	D3ZVS5 (UniProtKB/TrEMBL), A6HAP4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038967873 ⟸ XM_039111945
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063117719 ⟸ XM_063261649
- Peptide Label:	isoform X3

Protein Domains

XPG N-terminal XPG-I

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZVS5-F1-model_v2	AlphaFold	D3ZVS5	1-908	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694493

Promoter ID:

EPDNEW_R5018

Type:

single initiation site

Name:

Gen1_1

Description:

GEN1 Holliday junction 5' flap endonuclease

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	36,940,873 - 36,940,933	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1559792	AgrOrtholog
BioCyc Gene	G2FUF-38146	BioCyc
Ensembl Genes	ENSRNOG00000004667	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006470.5	UniProtKB/TrEMBL
Gene3D-CATH	5' to 3' exonuclease, C-terminal subdomain	UniProtKB/TrEMBL
	5'-nuclease	UniProtKB/TrEMBL
InterPro	5-3_exonuclease_C_sf	UniProtKB/TrEMBL
	GEN_chromo	UniProtKB/TrEMBL
	HhH2	UniProtKB/TrEMBL
	PIN_domain-like	UniProtKB/TrEMBL
	XPG/Rad2	UniProtKB/TrEMBL
	XPG/RAD2_endonuclease	UniProtKB/TrEMBL
	XPG_DNA_repair_N	UniProtKB/TrEMBL
KEGG Report	rno:298884	UniProtKB/TrEMBL
NCBI Gene	298884	ENTREZGENE
PANTHER	FLAP ENDONUCLEASE GEN HOMOLOG 1	UniProtKB/TrEMBL
	PTHR11081	UniProtKB/TrEMBL
Pfam	Chromo_2	UniProtKB/TrEMBL
	XPG_I	UniProtKB/TrEMBL
	XPG_N	UniProtKB/TrEMBL
PhenoGen	Gen1	PhenoGen
PRINTS	XPGRADSUPER	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004667	RatGTEx
SMART	HhH2	UniProtKB/TrEMBL
	XPGI	UniProtKB/TrEMBL
	XPGN	UniProtKB/TrEMBL
Superfamily-SCOP	5_3_exo_C	UniProtKB/TrEMBL
	SSF88723	UniProtKB/TrEMBL
UniProt	A6HAP4	ENTREZGENE, UniProtKB/TrEMBL
	D3ZVS5	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-06-14	Gen1	GEN1 Holliday junction 5' flap endonuclease	Gen1	Gen endonuclease homolog 1 (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-16	Gen1	Gen endonuclease homolog 1 (Drosophila)	Gen1	Gen homolog 1, endonuclease (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-11	Gen1	Gen homolog 1, endonuclease (Drosophila)	RGD1559792_predicted	similar to RIKEN cDNA 5830483C08 gene (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1559792_predicted	similar to RIKEN cDNA 5830483C08 gene (predicted)	LOC298884	similar to RIKEN cDNA 5830483C08 gene	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC298884	similar to RIKEN cDNA 5830483C08 gene			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar