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Gene: LOC690035 (similar to Protein KIAA0586) Rattus norvegicus
Symbol: LOC690035
Name: similar to Protein KIAA0586
Description: Predicted to be involved in cilium assembly; regulation of establishment of protein localization; and smoothened signaling pathway. Predicted to localize to the centriole; centrosome; and ciliary basal body. Human ortholog(s) of this gene implicated in Joubert syndrome 23 and short-rib thoracic dysplasia 14 with polydactyly. Orthologous to human KIAA0586 (KIAA0586); INTERACTS WITH bisphenol A; (-)-epigallocatechin 3-gallate (ortholog); atrazine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC299123; LOW QUALITY PROTEIN: protein TALPID3
Homo sapiens (human) : KIAA0586 (KIAA0586)  HGNC  Alliance
Mus musculus (house mouse) : 2700049A03Rik (RIKEN cDNA 2700049A03 gene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kiaa0586 (KIAA0586 ortholog)
Pan paniscus (bonobo/pygmy chimpanzee) : KIAA0586 (KIAA0586 ortholog)
Canis lupus familiaris (dog) : KIAA0586 (KIAA0586)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kiaa0586 (KIAA0586 ortholog)
Sus scrofa (pig) : KIAA0586 (KIAA0586 ortholog)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0693,562,775 - 93,667,857 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,563,446 - 93,667,675 (+)Ensembl
Rnor_5.06103,028,333 - 103,132,393 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4693,232,479 - 93,337,602 (+)NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on LOC690035
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1585176
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.