Moap1 (modulator of apoptosis 1) - Rat Genome Database

Name: Moap1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Moap1 (modulator of apoptosis 1) Rattus norvegicus

Analyze

Symbol:

Moap1

Name:

modulator of apoptosis 1

RGD ID:

1307230

Description:

Predicted to enable ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; positive regulation of organelle organization; and protein insertion into mitochondrial membrane. Predicted to be located in cytosol and mitochondrial outer membrane. Orthologous to human MOAP1 (modulator of apoptosis 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC299261; MGC109269

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MOAP1 (modulator of apoptosis 1)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Moap1 (modulator of apoptosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MOAP1 (modulator of apoptosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MOAP1 (modulator of apoptosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Moap1 (modulator of apoptosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MOAP1 (modulator of apoptosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MOAP1 (modulator of apoptosis 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MOAP1 (modulator of apoptosis 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Moap1 (modulator of apoptosis 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Related Pseudogenes:

Moap1-ps1

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	127,647,389 - 127,649,324 (-)	NCBI		GRCr8
mRatBN7.2	6	121,882,565 - 121,884,500 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	121,882,366 - 121,898,643 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	122,020,995 - 122,022,930 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	122,316,245 - 122,318,180 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	121,652,504 - 121,654,439 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	126,620,597 - 126,622,532 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	126,620,602 - 126,622,532 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	135,826,369 - 135,828,304 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	127,014,007 - 127,015,943 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	127,017,754 - 127,019,690 (-)	NCBI
Celera	6	119,369,488 - 119,371,424 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

achondrogenesis type IA (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

4,4'-sulfonyldiphenol (ISO)

all-trans-retinoic acid (ISO)

beauvericin (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

cobalt dichloride (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

diazinon (EXP)

dibutyl phthalate (ISO)

dieldrin (EXP)

doxorubicin (ISO)

endosulfan (EXP)

Enterolactone (ISO)

folic acid (ISO)

lead(0) (ISO)

N-acetyl-L-cysteine (ISO)

nickel dichloride (ISO)

p-menthan-3-ol (ISO)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

potassium chromate (ISO)

resorcinol (ISO)

testosterone (ISO)

urethane (ISO)

valproic acid (EXP,ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic signaling pathway (ISO)

extrinsic apoptotic signaling pathway in absence of ligand (ISO)

extrinsic apoptotic signaling pathway via death domain receptors (ISO)

intrinsic apoptotic signaling pathway in response to DNA damage (ISO)

positive regulation of apoptotic process (ISO)

positive regulation of autophagosome assembly (ISO)

positive regulation of release of cytochrome c from mitochondria (ISO)

protein insertion into mitochondrial membrane (ISO)

regulation of apoptotic process (IBA)

Cellular Component

cytoplasm (ISO)

cytosol (ISO)

EKC/KEOPS complex (IBA)

mitochondrial outer membrane (ISO)

mitochondrion (ISO)

Molecular Function

protein binding (ISO)

ubiquitin protein ligase binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11060313	PMID:15949439	PMID:16199525	PMID:19100260

Genomics

Comparative Map Data

Moap1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	127,647,389 - 127,649,324 (-)	NCBI		GRCr8
mRatBN7.2	6	121,882,565 - 121,884,500 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	121,882,366 - 121,898,643 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	122,020,995 - 122,022,930 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	122,316,245 - 122,318,180 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	121,652,504 - 121,654,439 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	126,620,597 - 126,622,532 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	126,620,602 - 126,622,532 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	135,826,369 - 135,828,304 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	127,014,007 - 127,015,943 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	127,017,754 - 127,019,690 (-)	NCBI
Celera	6	119,369,488 - 119,371,424 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

MOAP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	93,182,199 - 93,184,897 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	93,182,199 - 93,184,923 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	93,648,544 - 93,651,242 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	92,718,294 - 92,721,002 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	92,718,303 - 92,720,995	NCBI
Celera	14	73,702,548 - 73,705,256 (-)	NCBI		Celera
Cytogenetic Map	14	q32.12	NCBI
HuRef	14	73,828,980 - 73,831,688 (-)	NCBI		HuRef
CHM1_1	14	93,586,641 - 93,589,349 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	87,414,138 - 87,416,836 (-)	NCBI		T2T-CHM13v2.0

Moap1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	102,706,089 - 102,709,920 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	102,708,489 - 102,709,920 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	102,739,830 - 102,743,661 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	102,742,230 - 102,743,661 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	103,978,040 - 103,981,870 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	103,143,124 - 103,159,722 (-)	NCBI		MGSCv36	mm8
Celera	12	103,957,032 - 103,960,862 (-)	NCBI		Celera
Cytogenetic Map	12	E	NCBI
cM Map	12	52.14	NCBI

MOAP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	94,339,946 - 94,342,691 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	93,556,448 - 93,559,196 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	73,814,859 - 73,817,607 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	93,151,560 - 93,153,826 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	93,152,551 - 93,153,606 (-)	Ensembl	panpan1.1		panPan2

MOAP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ROS_Cfam_1.0	8	62,661,074 - 62,664,773 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	8	62,340,011 - 62,343,706 (-)	NCBI		UMICH_Zoey_3.1
UU_Cfam_GSD_1.0	8	62,720,875 - 62,724,554 (-)	NCBI		UU_Cfam_GSD_1.0

Moap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	12,339,994 - 12,355,785 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936733	1,111,958 - 1,113,010 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936733	1,111,256 - 1,113,651 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MOAP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	7	114,571,624 - 114,574,052 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	121,157,633 - 121,160,067 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MOAP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	24	70,920,083 - 70,921,138 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	58,170,806 - 58,173,527 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	298
Count of miRNA genes:	186
Interacting mature miRNAs:	211
Transcripts:	ENSRNOT00000038816
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
738034	Anxrr5	Anxiety related response QTL 5	5.9		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	6	84130881	129130881	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	85140138	130140138	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	85140138	130140138	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
1300076	Glom8	Glomerulus QTL 8	7	0.000000009	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	86894788	131894788	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	93701310	128713626	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	94968928	137848904	Rat
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	94968928	139968928	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	96833997	140994061	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	100364669	140994061	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	100671796	132340886	Rat
1331797	Bp213	Blood pressure QTL 213	3.291		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	104085867	128713626	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	105156861	140994061	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	106752656	132339866	Rat
737976	Pia24	Pristane induced arthritis QTL 24			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	6	112636280	140994061	Rat
1298087	Iddm18	Insulin dependent diabetes mellitus QTL 18		0.0001	urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	6	116506292	130245370	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium
Low	2	38	31	16	16	16	8	11	74	31	39	9	8
Below cutoff	1	5	26	25	3	25				4	2	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC109025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC091310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000038816 ⟹ ENSRNOP00000036467

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	121,882,366 - 121,885,062 (-)	Ensembl
Rnor_6.0 Ensembl	6	126,620,602 - 126,622,532 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000088000 ⟹ ENSRNOP00000073879

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	121,882,366 - 121,898,643 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000109746 ⟹ ENSRNOP00000095600

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	121,882,560 - 121,898,466 (-)	Ensembl

RefSeq Acc Id:

NM_001013101 ⟹ NP_001013119

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	127,647,389 - 127,649,324 (-)	NCBI
mRatBN7.2	6	121,882,565 - 121,884,500 (-)	NCBI
Rnor_6.0	6	126,620,597 - 126,622,532 (-)	NCBI
Rnor_5.0	6	135,826,369 - 135,828,304 (-)	NCBI
RGSC_v3.4	6	127,014,007 - 127,015,943 (-)	RGD
Celera	6	119,369,488 - 119,371,424 (-)	RGD

Sequence:

show sequence

TTGCGGCGGTGGCGGTCTCCTACCATGGCGGGGAAACGGGCGTAGGGAGCCCGTGTCCTCCATC
GCCGCATTGGGGACGTGATCCCCTGGTGTCTCCTGATGCCCGCAAAGGTCAGACGCCCTCTCCG
GAGCCTGAGCGGCTCCTGGACCTCTGCGTATTAGAGAGACGAGCACGCACATCTCTGAGCTGCG
GTGGGGCGGCGGCGGTGCCCTGGTCGAGTTAGGATTTAAATACCCTGGACACCATGACACTGAG
ACTCTTAGAAGACTGGTGCAGGGGGATGGACATGAACCCTCGGAAGGCACTGTTGGTTGCCGGC
ATCCCTCCGACCTGCGGAGTGGCAGACATCGAGGAGGCCCTGCAGGTTGGCCTTGCTCCCTTAG
GGGAGCACAGACTGCTTGGGAGGATGTTTAGGAGGGATGAGAACAAGAATGTAGCCTTGGTTGG
GCTCACAGTAGAGACCGGCAGTGCCCTAGTCCCCAAGGAGATACCTGCAAAAGGAGGTGTCTGG
AGAGTGATCTTTAAGCCTCCAGATGCTGATAGTGACTTTTTATGCAGATTAAATGAGTTTTTAA
AGGGAGAGGGCATGACAATGGGTGAATTAACCAGAGTTCTTGGGAATCGGAATGACCCTCTCTG
CCTAGACCAGAATGTGATGATCCCTGAAATTCGAGCACCCATGTTAGCACAGGCATTAGATGAG
GCTCTTAAGCCTACCCTGCAGTATCTGAGGTACAAAAAGCTGAGTGTGTTCTCAGGCAGGGATC
CTCCGGGACCAGGTGAGGAAGAATTTGAATCTTGGATGTTTCATACTTCCCAAGTAATGAAAAC
ATGGCAGGTGTCAGATGTAGAGAAAAGAAGGCGGTTGATGGAGAGCCTTAGAGGCCCAGCATTC
GAAATTATTCGAGTCCTCAAGATAAACAACCCGTTCATTACCGTTGCAGAATGCCTGAAGACGC
TTGAGACAATATTTGGGATTATTGATAATCCTAGGGCCTTGCAGGTCAGATACCTTACTACTTA
CCAGAAGAGTGGTGAAAAGCTCTCTGCCTATGTTCTGAGGTTGGAGCCTTTATTACAGAAGCTG
GTGCAGAAAGGAGCAATTGAGAAAGAAGTTGTGAATCAGGCCCGACTAGACCAAGTCATTGCTG
GGGCAATCCACAAGTCAGTTCGAAGAGAGCTTGGACTGCCAGAAGGTAGCCCTGCCCCAGGCTT
ATTGCAGTTGCTGACACTGATAAAAGATAAGGAGGCAGCAGAGGAAGAGGTCCTTCTTCAGGCC
GAATTAGAAGGACATTTCACTTGACCCAAGACCAGCAAGGCTGTCATGAGCAGAACATGATGGA
GGAGCTCATAGAAGTGATCAGCCCATCCCCCTTTGTGCTGCCAAAGTAACTTGCCCTTTGTCGT
GTTGTTCACCCCACTGAATGTCTCCCCAGTGTTTTACTGATACAAATGATGTCATTCTACACTG
GTAATTATTTAAATCAAAAGGTCATCTAGTACAGTGTTCTGCAAAGCTGGAGTTTATATGCATG
TTTAATAGTCTTATGTGATGGTGCTGTCCGTTAAAAATAATTTTCAGGTGTTGCCCACATTTAT
GCTGAAGACCCCGAGCCAAGGCTAGCTAAGTTATTTAAAGTTTCTTTATTATAAATCAGTTATT
GATTCTGTGCAATCAAAAATCACAACTGAGTGCTGTGGTCAATTCTACAACTATCTTTAGGTTT
GTGATATATCTGATGTGTTGCCAAAGGGTCTGCTTCTAAATGTCATTTTCTTAGAGTCATAGTA
TAAATAAAGAAATGCTAATAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013119	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91310	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000036467
	ENSRNOP00000036467.4
	ENSRNOP00000073879.2
	ENSRNOP00000087145.1
	ENSRNOP00000095600.1

RefSeq Acc Id:

NP_001013119 ⟸ NM_001013101

- UniProtKB:

Q5BJV6 (UniProtKB/TrEMBL), A0A0G2K6N3 (UniProtKB/TrEMBL), A0A8I6A7F7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTLRLLEDWCRGMDMNPRKALLVAGIPPTCGVADIEEALQVGLAPLGEHRLLGRMFRRDENKNV
ALVGLTVETGSALVPKEIPAKGGVWRVIFKPPDADSDFLCRLNEFLKGEGMTMGELTRVLGNRN
DPLCLDQNVMIPEIRAPMLAQALDEALKPTLQYLRYKKLSVFSGRDPPGPGEEEFESWMFHTSQ
VMKTWQVSDVEKRRRLMESLRGPAFEIIRVLKINNPFITVAECLKTLETIFGIIDNPRALQVRY
LTTYQKSGEKLSAYVLRLEPLLQKLVQKGAIEKEVVNQARLDQVIAGAIHKSVRRELGLPEGSP
APGLLQLLTLIKDKEAAEEEVLLQAELEGHFT

hide sequence

RefSeq Acc Id:

ENSRNOP00000036467 ⟸ ENSRNOT00000038816

RefSeq Acc Id:

ENSRNOP00000095600 ⟸ ENSRNOT00000109746

RefSeq Acc Id:

ENSRNOP00000073879 ⟸ ENSRNOT00000088000

Protein Domains

Paraneoplastic antigen Ma-like C-terminal Paraneoplastic antigen Ma-like N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5BJV6-F1-model_v2	AlphaFold	Q5BJV6	1-352	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694786

Promoter ID:

EPDNEW_R5310

Type:

initiation region

Name:

Moap1_1

Description:

modulator of apoptosis 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	126,622,550 - 126,622,610	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307230	AgrOrtholog
BioCyc Gene	G2FUF-36437	BioCyc
Ensembl Genes	ENSRNOG00000033970	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000066822	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038816	ENTREZGENE
	ENSRNOT00000038816.6	UniProtKB/TrEMBL
	ENSRNOT00000088000.2	UniProtKB/TrEMBL
	ENSRNOT00000105960.1	UniProtKB/TrEMBL
	ENSRNOT00000109746.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7311752	IMAGE-MGC_LOAD
InterPro	PNMA	UniProtKB/TrEMBL
	PNMA_C	UniProtKB/TrEMBL
	PNMA_N	UniProtKB/TrEMBL
KEGG Report	rno:299261	UniProtKB/TrEMBL
MGC_CLONE	MGC:109269	IMAGE-MGC_LOAD
NCBI Gene	299261	ENTREZGENE
PANTHER	MODULATOR OF APOPTOSIS 1	UniProtKB/TrEMBL
	PTHR23095	UniProtKB/TrEMBL
Pfam	PNMA	UniProtKB/TrEMBL
	PNMA_N	UniProtKB/TrEMBL
PhenoGen	Moap1	PhenoGen
RatGTEx	ENSRNOG00000033970	RatGTEx
	ENSRNOG00000066822	RatGTEx
UniProt	A0A0G2K6N3	ENTREZGENE
	A0A8I6A7F7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GLQ0_RAT	UniProtKB/TrEMBL
	Q5BJV6	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A0A0G2K6N3	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Moap1	modulator of apoptosis 1	Moap1_predicted	modulator of apoptosis 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Moap1_predicted	modulator of apoptosis 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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