Mir3581 (microRNA 3581) - Rat Genome Database

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Gene: Mir3581 (microRNA 3581) Rattus norvegicus
Analyze
Symbol: Mir3581
Name: microRNA 3581
RGD ID: 4888593
Description: Orthologous to human MIR656 (microRNA 656); INTERACTS WITH bisphenol A; cadmium dichloride; 17beta-estradiol (ortholog).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-3581; Mir409b; rno-mir-3581; rno-mir-409b
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86134,579,184 - 134,579,263 (-)NCBIGRCr8
mRatBN7.26128,757,779 - 128,757,858 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6128,757,779 - 128,757,858 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6128,937,018 - 128,937,097 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06129,232,850 - 129,232,929 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06128,594,475 - 128,594,554 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06133,893,418 - 133,893,497 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6133,893,418 - 133,893,497 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06143,055,775 - 143,055,854 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera6126,342,158 - 126,342,237 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Reduced expression of MIR409-3p in primary immune thrombocytopenia. Li H, etal., Br J Haematol. 2013 Apr;161(1):128-35. doi: 10.1111/bjh.12213. Epub 2013 Jan 30.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:20403161  


Genomics

Comparative Map Data
Mir3581
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86134,579,184 - 134,579,263 (-)NCBIGRCr8
mRatBN7.26128,757,779 - 128,757,858 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6128,757,779 - 128,757,858 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6128,937,018 - 128,937,097 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06129,232,850 - 129,232,929 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06128,594,475 - 128,594,554 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06133,893,418 - 133,893,497 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6133,893,418 - 133,893,497 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06143,055,775 - 143,055,854 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera6126,342,158 - 126,342,237 (-)NCBICelera
Cytogenetic Map6q32NCBI
MIR656
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814101,066,724 - 101,066,801 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14101,066,724 - 101,066,801 (+)EnsemblGRCh38hg38GRCh38
GRCh3714101,533,061 - 101,533,138 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614100,602,813 - 100,602,890 (+)NCBINCBI36Build 36hg18NCBI36
Celera1481,589,123 - 81,589,200 (+)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1481,716,435 - 81,716,512 (+)NCBIHuRef
CHM1_114101,472,083 - 101,472,160 (+)NCBICHM1_1
T2T-CHM13v2.01495,302,111 - 95,302,188 (+)NCBIT2T-CHM13v2.0

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:19988
Count of gene targets:9786
Count of transcripts:10624
Interacting mature miRNAs:rno-miR-409b
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat


Expression

RNA-SEQ Expression

appendage
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
mesoderm
nervous system
reproductive system
6 28 17 2 2 2 20 12 16 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_037374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000053696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6128,757,779 - 128,757,858 (-)Ensembl
Rnor_6.0 Ensembl6133,893,418 - 133,893,497 (-)Ensembl
RefSeq Acc Id: NR_037374
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86134,579,184 - 134,579,263 (-)NCBI
mRatBN7.26128,757,779 - 128,757,858 (-)NCBI
Rnor_6.06133,893,418 - 133,893,497 (-)NCBI
Rnor_5.06143,055,775 - 143,055,854 (-)NCBI
Celera6126,342,158 - 126,342,237 (-)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:4888593 AgrOrtholog
BioCyc Gene G2FUF-35923 BioCyc
Ensembl Genes ENSRNOG00000035573 Ensembl
miRBase MI0015454 ENTREZGENE
NCBI Gene 100526595 ENTREZGENE
PhenoGen Mir3581 PhenoGen
RatGTEx ENSRNOG00000035573 RatGTEx
RNAcentral URS000075A115 RNACentral
  URS000075B309 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-10-27 Mir3581  microRNA 3581  Mir3581  microRNA mir-3581  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-23 Mir3581  microRNA mir-3581      Symbol and Name status set to provisional 70820 PROVISIONAL