Mir3581 (microRNA 3581) - Rat Genome Database

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Gene: Mir3581 (microRNA 3581) Rattus norvegicus
Analyze
Symbol: Mir3581 (Ensembl: Mir409)
Name: microRNA 3581 (Ensembl:microRNA 409)
RGD ID: 4888593
Description: Orthologous to human MIR656 (microRNA 656); INTERACTS WITH bisphenol A; cadmium dichloride; 17beta-estradiol (ortholog).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-3581; Mir409b; rno-mir-3581; rno-mir-409b
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86134,579,184 - 134,579,263 (-)NCBIGRCr8
mRatBN7.26128,757,779 - 128,757,858 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6128,757,779 - 128,757,858 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6128,937,018 - 128,937,097 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06129,232,850 - 129,232,929 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06128,594,475 - 128,594,554 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06133,893,418 - 133,893,497 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6133,893,418 - 133,893,497 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06143,055,775 - 143,055,854 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera6126,342,158 - 126,342,237 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mir3581Ratautoimmune thrombocytopenic purpura treatmentISOMIR409 (Homo sapiens)10755694 RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mir3581RatKagami-Ogata syndrome  ISOMIR656 (Homo sapiens)8554872ClinVar Annotator: match by term: Paternal uniparental disomy 14ClinVarPMID:18176563
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mir3581Ratpapillary thyroid carcinoma  ISOMIR656 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:28030816

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Mir3581Rat17beta-estradiol decreases expressionISOMIR656 (Homo sapiens)6480464Estradiol results in decreased expression of MIR656 mRNACTDPMID:22113133
Mir3581Rat2-hydroxypropanoic acid increases expressionISOMIR656 (Homo sapiens)6480464Lactic Acid results in increased expression of MIR656 mRNACTDPMID:30851411
Mir3581Ratbenzo[a]pyrene increases methylationISOMIR656 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of MIR656 promoterCTDPMID:27901495
Mir3581Ratbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of MIR3581 geneCTDPMID:28505145
Mir3581Ratcadmium dichloride increases expressionEXP 6480464Cadmium Chloride results in increased expression of MIR3581 mRNACTDPMID:35525383
Mir3581Ratethanol decreases expressionISOMIR656 (Homo sapiens)6480464Ethanol results in decreased expression of MIR656CTDPMID:21878650
Mir3581Rathydrogen peroxide increases expressionISOMIR656 (Homo sapiens)6480464Hydrogen Peroxide results in increased expression of MIR656 mRNACTDPMID:26339600
Mir3581Ratrac-lactic acid increases expressionISOMIR656 (Homo sapiens)6480464Lactic Acid results in increased expression of MIR656 mRNACTDPMID:30851411
Mir3581Ratsodium arsenite decreases expressionISOMIR656 (Homo sapiens)6480464sodium arsenite results in decreased expression of MIR656 mRNACTDPMID:29207610

1 to 9 of 9 rows

#
Reference Title
Reference Citation
1. Reduced expression of MIR409-3p in primary immune thrombocytopenia. Li H, etal., Br J Haematol. 2013 Apr;161(1):128-35. doi: 10.1111/bjh.12213. Epub 2013 Jan 30.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:16381832   PMID:20403161  



Mir3581
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86134,579,184 - 134,579,263 (-)NCBIGRCr8
mRatBN7.26128,757,779 - 128,757,858 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6128,757,779 - 128,757,858 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6128,937,018 - 128,937,097 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06129,232,850 - 129,232,929 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06128,594,475 - 128,594,554 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06133,893,418 - 133,893,497 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6133,893,418 - 133,893,497 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06143,055,775 - 143,055,854 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera6126,342,158 - 126,342,237 (-)NCBICelera
Cytogenetic Map6q32NCBI
MIR656
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814101,066,724 - 101,066,801 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14101,066,724 - 101,066,801 (+)EnsemblGRCh38hg38GRCh38
GRCh3714101,533,061 - 101,533,138 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614100,602,813 - 100,602,890 (+)NCBINCBI36Build 36hg18NCBI36
Celera1481,589,123 - 81,589,200 (+)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1481,716,435 - 81,716,512 (+)NCBIHuRef
CHM1_114101,472,083 - 101,472,160 (+)NCBICHM1_1
T2T-CHM13v2.01495,302,111 - 95,302,188 (+)NCBIT2T-CHM13v2.0

.

Predicted Targets
Summary Value
Count of predictions:19988
Count of gene targets:9786
Count of transcripts:10624
Interacting mature miRNAs:rno-miR-409b
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat

1 to 10 of 25 rows



appendage
ectoderm
endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
mesoderm
nervous system
reproductive system
6 28 17 2 2 2 20 12 16 6


RefSeq Transcripts NR_037374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000053696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6128,757,779 - 128,757,858 (-)Ensembl
Rnor_6.0 Ensembl6133,893,418 - 133,893,497 (-)Ensembl
RefSeq Acc Id: NR_037374
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86134,579,184 - 134,579,263 (-)NCBI
mRatBN7.26128,757,779 - 128,757,858 (-)NCBI
Rnor_6.06133,893,418 - 133,893,497 (-)NCBI
Rnor_5.06143,055,775 - 143,055,854 (-)NCBI
Celera6126,342,158 - 126,342,237 (-)NCBI
Sequence:

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



Database
Acc Id
Source(s)
BioCyc Gene G2FUF-35923 BioCyc
Ensembl Genes ENSRNOG00000035573 Ensembl
miRBase MI0015454 ENTREZGENE
NCBI Gene 100526595 ENTREZGENE
PhenoGen Mir3581 PhenoGen
RatGTEx ENSRNOG00000035573 RatGTEx
RNAcentral URS000075A115 RNACentral
  URS000075B309 RNACentral


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-10-27 Mir3581  microRNA 3581  Mir3581  microRNA mir-3581  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-11-23 Mir3581  microRNA mir-3581      Symbol and Name status set to provisional 70820 PROVISIONAL