Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Dicer1 (dicer 1 ribonuclease III) Rattus norvegicus
Symbol: Dicer1
Name: dicer 1 ribonuclease III
RGD ID: 1309381
Description: Predicted to have RNA binding activity; endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters; and protein domain specific binding activity. Predicted to be involved in several processes, including animal organ development; negative regulation of gene expression; and nervous system development. Localizes to dendrite; endoplasmic reticulum-Golgi intermediate compartment; and growth cone. Human ortholog(s) of this gene implicated in multinodular goiter and pleuropulmonary blastoma. Orthologous to human DICER1 (dicer 1, ribonuclease III); PARTICIPATES IN microRNA pathway; INTERACTS WITH amphetamine; bisphenol A; dexamethasone.
Type: protein-coding
RefSeq Status: MODEL
Also known as: dicer 1, ribonuclease type III; Dicer1, Dcr-1 homolog; Dicer1, Dcr-1 homolog (Drosophila); endoribonuclease Dicer; LOC299284
Homo sapiens (human) : DICER1 (dicer 1, ribonuclease III)  HGNC  Alliance
Mus musculus (house mouse) : Dicer1 (dicer 1, ribonuclease type III)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dicer1 (dicer 1, ribonuclease III)
Pan paniscus (bonobo/pygmy chimpanzee) : DICER1 (dicer 1, ribonuclease III)
Canis lupus familiaris (dog) : DICER1 (dicer 1, ribonuclease III)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dicer1 (dicer 1, ribonuclease III)
Sus scrofa (pig) : DICER1 (dicer 1, ribonuclease III)
Chlorocebus sabaeus (African green monkey) : DICER1 (dicer 1, ribonuclease III)
Heterocephalus glaber (naked mole-rat) : Dicer1 (dicer 1, ribonuclease III)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06128,388,084 - 128,453,234 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6128,388,053 - 128,434,183 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06137,586,335 - 137,633,706 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46128,777,468 - 128,838,780 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16128,781,378 - 128,842,495 (-)NCBI
Celera6121,106,680 - 121,167,957 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Dicer1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309381
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.