Entpd5 (ectonucleoside triphosphate diphosphohydrolase 5) - Rat Genome Database

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Gene: Entpd5 (ectonucleoside triphosphate diphosphohydrolase 5) Rattus norvegicus
Analyze
Symbol: Entpd5
Name: ectonucleoside triphosphate diphosphohydrolase 5
RGD ID: 735219
Description: Predicted to enable nucleoside-diphosphatase activity. Predicted to be involved in several processes, including UDP catabolic process; positive regulation of glycolytic process; and regulation of phosphatidylinositol 3-kinase signaling. Predicted to act upstream of with a positive effect on 'de novo' post-translational protein folding; UDP-glucose metabolic process; and protein N-linked glycosylation. Located in endoplasmic reticulum lumen. Orthologous to human ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive)); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GDPase ENTPD5; guanosine-diphosphatase ENTPD5; NTPDase 5; Pcph; UDPase ENTPD5; uridine-diphosphatase ENTPD5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26104,019,095 - 104,055,311 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl6104,019,185 - 104,055,530 (-)Ensembl
Rnor_6.06108,087,677 - 108,123,811 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6108,087,418 - 108,120,579 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06117,422,586 - 117,458,720 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,439,822 - 108,469,756 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16108,443,290 - 108,473,213 (-)NCBI
Celera6101,850,366 - 101,880,006 (-)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-4,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium sulfate  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorohydrocarbon  (EXP)
chloroprene  (EXP,ISO)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
curcumin  (EXP)
cyclosporin A  (ISO)
cyproconazole  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
diethyl maleate  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
hydrogen peroxide  (ISO)
indole-3-methanol  (EXP)
L-methionine  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP)
mercury dichloride  (EXP)
methylmercury chloride  (EXP,ISO)
methylphenidate  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
sodium arsenite  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Deregulated expression of the PCPH proto-oncogene in rat mammary tumors induced with 7,12-dimethylbenzanthracene. Solanas M, etal., Mol Carcinog 2002 Apr;33(4):219-27.
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Glycoprotein reglucosylation and nucleotide sugar utilization in the secretory pathway: identification of a nucleoside diphosphatase in the endoplasmic reticulum. Trombetta ES and Helenius A, EMBO J. 1999 Jun 15;18(12):3282-92. doi: 10.1093/emboj/18.12.3282.
Additional References at PubMed
PMID:10400613   PMID:11041857   PMID:21074248   PMID:23376485   PMID:27832996  


Genomics

Comparative Map Data
Entpd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26104,019,095 - 104,055,311 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl6104,019,185 - 104,055,530 (-)Ensembl
Rnor_6.06108,087,677 - 108,123,811 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6108,087,418 - 108,120,579 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06117,422,586 - 117,458,720 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,439,822 - 108,469,756 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16108,443,290 - 108,473,213 (-)NCBI
Celera6101,850,366 - 101,880,006 (-)NCBICelera
Cytogenetic Map6q31NCBI
ENTPD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,955,329 - 74,019,288 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1473,958,010 - 74,019,399 (-)EnsemblGRCh38hg38GRCh38
GRCh371474,422,032 - 74,485,991 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,502,925 - 73,555,714 (-)NCBINCBI36hg18NCBI36
Build 341473,502,935 - 73,552,386NCBI
Celera1454,470,115 - 54,522,978 (-)NCBI
Cytogenetic Map14q24.3NCBI
HuRef1454,600,020 - 54,652,679 (-)NCBIHuRef
CHM1_11474,372,748 - 74,425,579 (-)NCBICHM1_1
T2T-CHM13v2.01468,162,983 - 68,226,953 (-)NCBI
Entpd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,420,649 - 84,455,803 (-)NCBIGRCm39mm39
GRCm39 Ensembl1284,420,631 - 84,455,803 (-)Ensembl
GRCm381284,373,875 - 84,409,029 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,373,857 - 84,409,029 (-)EnsemblGRCm38mm10GRCm38
MGSCv371285,714,807 - 85,749,979 (-)NCBIGRCm37mm9NCBIm37
MGSCv361285,263,605 - 85,298,777 (-)NCBImm8
Celera1285,828,883 - 85,864,542 (-)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.18NCBI
Entpd5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555231,421,749 - 1,441,829 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555231,407,812 - 1,441,829 (+)NCBIChiLan1.0ChiLan1.0
ENTPD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11473,376,684 - 73,418,946 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1473,376,684 - 73,410,468 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01454,522,428 - 54,578,501 (-)NCBIMhudiblu_PPA_v0panPan3
ENTPD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1847,193,463 - 47,245,865 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl847,196,439 - 47,229,964 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,877,776 - 46,930,168 (-)NCBI
ROS_Cfam_1.0847,422,519 - 47,473,081 (-)NCBI
ROS_Cfam_1.0 Ensembl847,414,872 - 47,464,118 (-)Ensembl
UMICH_Zoey_3.1847,090,154 - 47,142,547 (-)NCBI
UNSW_CanFamBas_1.0847,108,174 - 47,160,585 (-)NCBI
UU_Cfam_GSD_1.0847,498,539 - 47,550,882 (-)NCBI
Entpd5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864028,789,021 - 28,828,004 (+)NCBI
SpeTri2.0NW_0049364883,241,004 - 3,280,360 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENTPD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl797,262,305 - 97,316,571 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1797,270,698 - 97,316,578 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27103,024,868 - 103,070,633 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ENTPD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12451,176,137 - 51,234,575 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2451,181,859 - 51,231,078 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605339,386,948 - 39,459,247 (-)NCBIVero_WHO_p1.0
Entpd5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473427,570,815 - 27,610,766 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473427,568,738 - 27,610,046 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
Entpd5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26104,021,871 - 104,022,135 (+)MAPPERmRatBN7.2
Rnor_6.06108,090,454 - 108,090,717NCBIRnor6.0
Rnor_5.06117,455,679 - 117,455,943NCBIRnor5.0
RGSC_v3.46108,439,622 - 108,439,885UniSTSRGSC3.4
Celera6101,850,166 - 101,850,429UniSTS
Cytogenetic Map6q31UniSTS
AF006482  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.06117,455,563 - 117,455,665UniSTSRnor5.0
Cytogenetic Map6q31UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:217
Count of miRNA genes:160
Interacting mature miRNAs:174
Transcripts:ENSRNOT00000041163
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 11 51 35 19 35 5 8 29 27 31 11 5
Low 32 6 6 6 3 3 45 8 10 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000041163   ⟹   ENSRNOP00000041026
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6104,019,185 - 104,042,409 (-)Ensembl
Rnor_6.0 Ensembl6108,087,418 - 108,120,579 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097901   ⟹   ENSRNOP00000083944
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6104,019,185 - 104,055,530 (-)Ensembl
RefSeq Acc Id: NM_199394   ⟹   NP_955426
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,022,072 - 104,052,004 (-)NCBI
Rnor_6.06108,090,654 - 108,120,581 (-)NCBI
Rnor_5.06117,422,586 - 117,458,720 (+)NCBI
RGSC_v3.46108,439,822 - 108,469,756 (-)RGD
Celera6101,850,366 - 101,880,006 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240343   ⟹   XP_006240405
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,019,095 - 104,055,159 (-)NCBI
Rnor_6.06108,087,677 - 108,123,701 (-)NCBI
Rnor_5.06117,422,586 - 117,458,720 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240344   ⟹   XP_006240406
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,019,095 - 104,055,311 (-)NCBI
Rnor_6.06108,087,677 - 108,123,811 (-)NCBI
Rnor_5.06117,422,586 - 117,458,720 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240345   ⟹   XP_006240407
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,019,095 - 104,055,159 (-)NCBI
Rnor_6.06108,087,677 - 108,123,701 (-)NCBI
Rnor_5.06117,422,586 - 117,458,720 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240346   ⟹   XP_006240408
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,019,095 - 104,044,332 (-)NCBI
Rnor_6.06108,087,677 - 108,112,405 (-)NCBI
Rnor_5.06117,422,586 - 117,458,720 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594151   ⟹   XP_017449640
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,019,095 - 104,055,159 (-)NCBI
Rnor_6.06108,087,677 - 108,123,702 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594152   ⟹   XP_017449641
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,019,095 - 104,055,311 (-)NCBI
Rnor_6.06108,087,677 - 108,123,811 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594153   ⟹   XP_017449642
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,019,095 - 104,055,159 (-)NCBI
Rnor_6.06108,087,677 - 108,123,702 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_955426   ⟸   NM_199394
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: XP_006240406   ⟸   XM_006240344
- Peptide Label: isoform X2
- UniProtKB: F1LPB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240405   ⟸   XM_006240343
- Peptide Label: isoform X2
- UniProtKB: F1LPB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240407   ⟸   XM_006240345
- Peptide Label: isoform X2
- UniProtKB: F1LPB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240408   ⟸   XM_006240346
- Peptide Label: isoform X2
- UniProtKB: F1LPB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449641   ⟸   XM_017594152
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017449642   ⟸   XM_017594153
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017449640   ⟸   XM_017594151
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000041026   ⟸   ENSRNOT00000041163
RefSeq Acc Id: ENSRNOP00000083944   ⟸   ENSRNOT00000097901

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P6S9-F1-model_v2 AlphaFold Q6P6S9 1-427 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735219 AgrOrtholog
BioCyc Gene G2FUF-36821 BioCyc
Ensembl Genes ENSRNOG00000033206 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000041026 ENTREZGENE
  ENSRNOP00000041026.4 UniProtKB/TrEMBL
  ENSRNOP00000083944 ENTREZGENE
  ENSRNOP00000083944.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041163 ENTREZGENE
  ENSRNOT00000041163.4 UniProtKB/TrEMBL
  ENSRNOT00000097901 ENTREZGENE
  ENSRNOT00000097901.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5597848 IMAGE-MGC_LOAD
InterPro GDA1_CD39_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:314312 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72569 IMAGE-MGC_LOAD
NCBI Gene 314312 ENTREZGENE
PANTHER PTHR11782 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GDA1_CD39 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Entpd5 PhenoGen
PROSITE GDA1_CD39_NTPASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZWS8_RAT UniProtKB/TrEMBL
  ENTP5_RAT UniProtKB/Swiss-Prot
  F1LPB8 ENTREZGENE, UniProtKB/TrEMBL
  Q6P6S9 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Entpd5  ectonucleoside triphosphate diphosphohydrolase 5      Symbol and Name status set to approved 1299863 APPROVED