Catsperb (cation channel sperm associated auxiliary subunit beta) - Rat Genome Database

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Gene: Catsperb (cation channel sperm associated auxiliary subunit beta) Rattus norvegicus
Analyze
Symbol: Catsperb
Name: cation channel sperm associated auxiliary subunit beta
RGD ID: 6500065
Description: Predicted to be located in sperm principal piece. Predicted to be part of CatSper complex. Orthologous to human CATSPERB (cation channel sperm associated auxiliary subunit beta); INTERACTS WITH 17beta-estradiol (ortholog); 4,4'-sulfonyldiphenol (ortholog); Aflatoxin B2 alpha (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cation channel sperm-associated auxiliary subunit beta; cation channel sperm-associated protein subunit beta; cation channel sperm-associated protein subunit beta-like; catsper channel auxiliary subunit beta; LOC100910102; LOC100911278; LOC102553227; uncharacterized LOC102553227
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86126,148,156 - 126,526,814 (-)NCBIGRCr8
mRatBN7.26120,418,606 - 120,713,160 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6120,418,609 - 120,707,182 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.06125,153,124 - 125,391,303 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06134,372,650 - 134,464,745 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera6117,937,554 - 118,216,544 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17478420   PMID:21224844  


Genomics

Comparative Map Data
Catsperb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86126,148,156 - 126,526,814 (-)NCBIGRCr8
mRatBN7.26120,418,606 - 120,713,160 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6120,418,609 - 120,707,182 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.06125,153,124 - 125,391,303 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06134,372,650 - 134,464,745 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera6117,937,554 - 118,216,544 (-)NCBICelera
Cytogenetic Map6q32NCBI
CATSPERB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381491,580,698 - 91,732,086 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1491,580,696 - 91,780,707 (-)EnsemblGRCh38hg38GRCh38
GRCh371492,047,042 - 92,198,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361491,116,871 - 91,268,166 (-)NCBINCBI36Build 36hg18NCBI36
Build 341491,116,870 - 91,268,166NCBI
Celera1472,095,740 - 72,251,049 (-)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1472,223,868 - 72,379,224 (-)NCBIHuRef
CHM1_11491,985,196 - 92,136,481 (-)NCBICHM1_1
T2T-CHM13v2.01485,805,904 - 85,961,560 (-)NCBIT2T-CHM13v2.0
Catsperb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912101,370,904 - 101,592,268 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12101,370,912 - 101,592,268 (+)EnsemblGRCm39 Ensembl
GRCm3812101,404,645 - 101,626,009 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12101,404,653 - 101,626,009 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712102,642,883 - 102,864,219 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612101,805,732 - 102,027,000 (+)NCBIMGSCv36mm8
Celera12102,632,071 - 102,833,468 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1251.23NCBI
Catsperb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543813,822,642 - 13,978,777 (-)NCBIChiLan1.0ChiLan1.0
CATSPERB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21592,726,912 - 92,881,286 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11491,943,421 - 92,097,795 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01472,203,805 - 72,357,311 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11491,550,690 - 91,701,891 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1491,550,690 - 91,699,419 (-)Ensemblpanpan1.1panPan2
CATSPERB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.18910,625 - 1,058,325 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl8908,853 - 1,053,292 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha8936,645 - 1,078,063 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.08960,085 - 1,107,916 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.18898,270 - 1,046,059 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.08854,092 - 1,002,101 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.08981,892 - 1,123,267 (-)NCBIUU_Cfam_GSD_1.0
Catsperb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864013,456,402 - 13,567,641 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648818,501,602 - 18,595,781 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CATSPERB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7113,201,004 - 113,297,405 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17113,201,785 - 113,293,597 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27119,753,812 - 119,868,950 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CATSPERB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12469,339,174 - 69,499,283 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605356,589,624 - 56,737,404 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Catsperb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473410,973,392 - 11,124,351 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Catsperb
1638 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat

Markers in Region
PMC311070P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X152,201,365 - 152,201,695 (-)MAPPERmRatBN7.2
mRatBN7.26120,475,884 - 120,476,214 (+)MAPPERmRatBN7.2
Rnor_6.06125,212,363 - 125,212,692NCBIRnor6.0
Rnor_6.0X156,293,321 - 156,293,650NCBIRnor6.0
Rnor_5.06134,431,064 - 134,431,393UniSTSRnor5.0
Rnor_5.01152,034,062 - 152,034,391UniSTSRnor5.0
RGSC_v3.46125,501,696 - 125,502,025UniSTSRGSC3.4
RGSC_v3.4X160,191,702 - 160,192,031UniSTSRGSC3.4
Celera1135,695,942 - 135,696,271UniSTS
Celera6117,995,079 - 117,995,408UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic MapXq37UniSTS
PMC85812P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X152,203,604 - 152,204,044 (-)MAPPERmRatBN7.2
mRatBN7.26120,474,842 - 120,475,052 (+)MAPPERmRatBN7.2
Rnor_6.06125,211,321 - 125,211,530NCBIRnor6.0
Rnor_6.0X156,290,972 - 156,291,411NCBIRnor6.0
Rnor_5.06134,430,022 - 134,430,231UniSTSRnor5.0
Rnor_5.01152,031,713 - 152,032,152UniSTSRnor5.0
RGSC_v3.46125,500,654 - 125,500,863UniSTSRGSC3.4
RGSC_v3.4X160,189,353 - 160,189,792UniSTSRGSC3.4
Celera1135,693,593 - 135,694,032UniSTS
Celera6117,994,037 - 117,994,246UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic MapXq37UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000117511   ⟹   ENSRNOP00000093052
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6120,418,609 - 120,707,182 (-)Ensembl
RefSeq Acc Id: XM_063262695   ⟹   XP_063118765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,148,156 - 126,478,061 (-)NCBI
RefSeq Acc Id: XM_063262696   ⟹   XP_063118766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,148,156 - 126,526,814 (-)NCBI
RefSeq Acc Id: XM_063262697   ⟹   XP_063118767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,148,156 - 126,346,676 (-)NCBI
RefSeq Acc Id: XM_063262698   ⟹   XP_063118768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,148,156 - 126,295,395 (-)NCBI
RefSeq Acc Id: XM_063262699   ⟹   XP_063118769
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86126,148,156 - 126,241,008 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063118765 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118766 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118767 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118768 (Get FASTA)   NCBI Sequence Viewer  
  XP_063118769 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000093052.1
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000093052   ⟸   ENSRNOT00000117511
RefSeq Acc Id: XP_063118766   ⟸   XM_063262696
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118765   ⟸   XM_063262695
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063118767   ⟸   XM_063262697
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118768   ⟸   XM_063262698
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063118769   ⟸   XM_063262699
- Peptide Label: isoform X3
Protein Domains
Cation channel sperm-associated auxiliary subunit   Cation channel sperm-associated protein subunit beta

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:6500065 AgrOrtholog
BioCyc Gene G2FUF-36474 BioCyc
Ensembl Genes ENSRNOG00000063175 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000117511.1 UniProtKB/TrEMBL
InterPro CATSPERB UniProtKB/TrEMBL
  CATSPERB_1st UniProtKB/TrEMBL
  CATSPERB_2nd UniProtKB/TrEMBL
  CATSPERB_C UniProtKB/TrEMBL
NCBI Gene LOC100910102 ENTREZGENE
PANTHER CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT BETA UniProtKB/TrEMBL
  PTHR14705 UniProtKB/TrEMBL
Pfam CATSPERB UniProtKB/TrEMBL
  CATSPERB_1st UniProtKB/TrEMBL
  CATSPERB_2nd UniProtKB/TrEMBL
PhenoGen Catsperb PhenoGen
RatGTEx ENSRNOG00000063175 RatGTEx
UniProt A0A8I6AWH2_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Catsperb  cation channel sperm associated auxiliary subunit beta  Catsperb  cation channel sperm associated auxiliary subunit beta  Data merged from RGD:149736165 737654 PROVISIONAL
2021-08-09 Catsperb  cation channel sperm associated auxiliary subunit beta      Symbol and Name status set to provisional 45752 PROVISIONAL
2021-03-09 Catsperb  cation channel sperm associated auxiliary subunit beta  LOC100911278  cation channel sperm-associated protein subunit beta-like  Data merged from RGD:6493937 737654 PROVISIONAL
2016-02-11 Catsperb  cation channel sperm associated auxiliary subunit beta  Catsperb  catsper channel auxiliary subunit beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-07-29 Catsperb  catsper channel auxiliary subunit beta  LOC102553227  uncharacterized LOC102553227  Data merged from RGD:7696453 737654 PROVISIONAL
2014-11-07 Catsperb  catsper channel auxiliary subunit beta  LOC100910102  cation channel sperm-associated protein subunit beta-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102553227  uncharacterized LOC102553227      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100910102  cation channel sperm-associated protein subunit beta-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100911278  cation channel sperm-associated protein subunit beta-like      Symbol and Name status set to provisional 70820 PROVISIONAL