(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SPTLC2 mRNA] CTD PMID:31150632 (-)-epigallocatechin 3-gallate multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SPTLC2 mRNA CTD PMID:22079256 (1->4)-beta-D-glucan multiple interactions ISO Sptlc2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SPTLC2 mRNA CTD PMID:36331819 1,2-dimethylhydrazine decreases expression ISO Sptlc2 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of SPTLC2 mRNA CTD PMID:22206623 1-benzylpiperazine increases expression EXP 6480464 N-benzylpiperazine results in increased expression of SPTLC2 mRNA CTD PMID:26821219 17beta-estradiol increases expression ISO Sptlc2 (Mus musculus) 6480464 Estradiol results in increased expression of SPTLC2 mRNA CTD PMID:15289156 2,2',4,4',5,5'-hexachlorobiphenyl increases expression ISO SPTLC2 (Homo sapiens) 6480464 2 more ... CTD PMID:34627992 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Sptlc2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of SPTLC2 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin promotes the reaction [[AHR protein binds to ARNT protein] which binds to SPTLC2 promoter] CTD PMID:34097992 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Sptlc2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of SPTLC2 mRNA CTD PMID:28238261 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO SPTLC2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of SPTLC2 mRNA CTD PMID:23152189 2,3,7,8-Tetrachlorodibenzofuran multiple interactions ISO Sptlc2 (Mus musculus) 6480464 2 more ... CTD PMID:34097992 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO Sptlc2 (Mus musculus) 6480464 2 more ... CTD PMID:34097992 2-acetamidofluorene increases expression ISO Sptlc2 (Mus musculus) 6480464 2-Acetylaminofluorene results in increased expression of SPTLC2 mRNA CTD PMID:17317680 2-hydroxypropanoic acid decreases expression ISO SPTLC2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of SPTLC2 mRNA CTD PMID:30851411 3,3',5-triiodo-L-thyronine increases expression ISO SPTLC2 (Homo sapiens) 6480464 Triiodothyronine results in increased expression of SPTLC2 mRNA CTD PMID:23397585 3,4-methylenedioxymethamphetamine decreases expression ISO Sptlc2 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of SPTLC2 mRNA CTD PMID:26251327 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of SPTLC2 protein CTD PMID:34915118 3-methylcholanthrene multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 Methylcholanthrene promotes the reaction [AHR protein binds to SPTLC2 promoter] CTD PMID:20348232 4,4'-diaminodiphenylmethane decreases expression ISO Sptlc2 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of SPTLC2 mRNA CTD PMID:18648102 8'-apo-beta,psi-caroten-8'-al affects expression ISO SPTLC2 (Homo sapiens) 6480464 apocarotenal affects the expression of SPTLC2 mRNA CTD PMID:17034753 acetamide increases expression EXP 6480464 acetamide results in increased expression of SPTLC2 mRNA CTD PMID:31881176 aflatoxin B1 decreases expression ISO Sptlc2 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of SPTLC2 mRNA CTD PMID:19770486 all-trans-retinoic acid increases expression ISO SPTLC2 (Homo sapiens) 6480464 Tretinoin results in increased expression of SPTLC2 mRNA CTD PMID:33167477 amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of SPTLC2 mRNA CTD PMID:30779732 aristolochic acid A decreases expression ISO SPTLC2 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of SPTLC2 mRNA CTD PMID:33212167 Aroclor 1254 decreases expression ISO Sptlc2 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of SPTLC2 mRNA CTD PMID:23650126 arsenite(3-) multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 arsenite inhibits the reaction [G3BP1 protein binds to SPTLC2 mRNA] CTD PMID:32406909 arsenous acid increases expression ISO SPTLC2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of SPTLC2 mRNA CTD PMID:20458559 benzo[a]pyrene diol epoxide I decreases expression ISO SPTLC2 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 and PMID:20382639 benzo[e]pyrene decreases methylation ISO SPTLC2 (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of SPTLC2 intron CTD PMID:30157460 beta-carotene affects expression ISO SPTLC2 (Homo sapiens) 6480464 beta Carotene affects the expression of SPTLC2 mRNA CTD PMID:17034753 butanal decreases expression ISO SPTLC2 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of SPTLC2 mRNA CTD PMID:26079696 calcitriol increases expression ISO SPTLC2 (Homo sapiens) 6480464 Calcitriol results in increased expression of SPTLC2 mRNA CTD PMID:16002434 choline multiple interactions ISO Sptlc2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPTLC2 mRNA CTD PMID:20938992 cisplatin affects response to substance ISO SPTLC2 (Homo sapiens) 6480464 SPTLC2 protein affects the susceptibility to Cisplatin CTD PMID:16217747 cobalt dichloride increases expression ISO SPTLC2 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of SPTLC2 mRNA CTD PMID:19376846 cyclosporin A decreases expression ISO Sptlc2 (Mus musculus) 6480464 Cyclosporine results in decreased expression of SPTLC2 mRNA CTD PMID:19770486 cyclosporin A increases expression ISO SPTLC2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of SPTLC2 mRNA CTD PMID:20106945 and PMID:25562108 deoxynivalenol decreases expression ISO SPTLC2 (Homo sapiens) 6480464 deoxynivalenol results in decreased expression of SPTLC2 mRNA CTD PMID:31863870 diarsenic trioxide increases expression ISO SPTLC2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of SPTLC2 mRNA CTD PMID:20458559 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of SPTLC2 mRNA CTD PMID:21266533 diethylstilbestrol increases expression ISO Sptlc2 (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of SPTLC2 mRNA CTD PMID:15289156 divanadium pentaoxide affects expression ISO Sptlc2 (Mus musculus) 6480464 vanadium pentoxide affects the expression of SPTLC2 mRNA CTD PMID:26210822 dorsomorphin multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPTLC2 mRNA CTD PMID:27188386 entinostat increases expression ISO SPTLC2 (Homo sapiens) 6480464 entinostat results in increased expression of SPTLC2 mRNA CTD PMID:26272509 entinostat multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPTLC2 mRNA CTD PMID:27188386 ethanol affects splicing ISO Sptlc2 (Mus musculus) 6480464 Ethanol affects the splicing of SPTLC2 mRNA CTD PMID:30319688 flutamide increases expression EXP 6480464 Flutamide results in increased expression of SPTLC2 mRNA CTD PMID:24136188 folic acid multiple interactions ISO Sptlc2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPTLC2 mRNA CTD PMID:20938992 genistein increases expression ISO Sptlc2 (Mus musculus) 6480464 Genistein results in increased expression of SPTLC2 mRNA CTD PMID:15289156 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of SPTLC2 mRNA CTD PMID:22061828 and PMID:33387578 GW 4064 multiple interactions ISO Sptlc2 (Mus musculus) 6480464 GW 4064 inhibits the reaction [[caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA] CTD PMID:28223344 isoprenaline increases expression ISO Sptlc2 (Mus musculus) 6480464 Isoproterenol results in increased expression of SPTLC2 mRNA CTD PMID:20003209 ivermectin decreases expression ISO SPTLC2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of SPTLC2 protein CTD PMID:32959892 L-methionine multiple interactions ISO Sptlc2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPTLC2 mRNA CTD PMID:20938992 lithocholic acid increases expression ISO Sptlc2 (Mus musculus) 6480464 Lithocholic Acid results in increased expression of SPTLC2 mRNA CTD PMID:21480330 methapyrilene decreases methylation ISO SPTLC2 (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of SPTLC2 intron CTD PMID:30157460 methidathion decreases expression ISO Sptlc2 (Mus musculus) 6480464 methidathion results in decreased expression of SPTLC2 mRNA CTD PMID:34813904 methotrexate affects expression ISO Sptlc2 (Mus musculus) 6480464 Methotrexate affects the expression of SPTLC2 mRNA CTD PMID:18502557 methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of SPTLC2 gene CTD PMID:35440735 nickel atom increases expression ISO SPTLC2 (Homo sapiens) 6480464 Nickel results in increased expression of SPTLC2 mRNA CTD PMID:24768652 and PMID:25583101 ozone multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which affects the expression of SPTLC2 mRNA CTD PMID:35430440 paracetamol affects expression ISO Sptlc2 (Mus musculus) 6480464 Acetaminophen affects the expression of SPTLC2 mRNA CTD PMID:17562736 paracetamol increases expression ISO SPTLC2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of SPTLC2 mRNA CTD PMID:21420995 paraquat increases expression ISO Sptlc2 (Mus musculus) 6480464 Paraquat results in increased expression of SPTLC2 mRNA CTD PMID:36108500 pentachlorophenol increases expression ISO Sptlc2 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of SPTLC2 mRNA CTD PMID:23892564 pentanal decreases expression ISO SPTLC2 (Homo sapiens) 6480464 pentanal results in decreased expression of SPTLC2 mRNA CTD PMID:26079696 perfluorooctane-1-sulfonic acid multiple interactions ISO Sptlc2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of SPTLC2 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of SPTLC2 mRNA CTD PMID:36331819 perfluorooctanoic acid decreases expression ISO SPTLC2 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of SPTLC2 protein CTD PMID:26879310 phenethyl caffeate multiple interactions ISO Sptlc2 (Mus musculus) 6480464 [caffeic acid phenethyl ester co-treated with Dietary Fats] results in decreased expression of SPTLC2 mRNA more ... CTD PMID:28223344 phenobarbital multiple interactions ISO Sptlc2 (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of SPTLC2 mRNA] CTD PMID:19482888 phenobarbital increases expression ISO Sptlc2 (Mus musculus) 6480464 Phenobarbital results in increased expression of SPTLC2 mRNA CTD PMID:19482888 pirinixic acid increases expression ISO Sptlc2 (Mus musculus) 6480464 pirinixic acid results in increased expression of SPTLC2 mRNA CTD PMID:17426115 and PMID:18301758 piroxicam decreases expression ISO SPTLC2 (Homo sapiens) 6480464 Piroxicam results in decreased expression of SPTLC2 mRNA CTD PMID:21858171 potassium chromate multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SPTLC2 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO SPTLC2 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of SPTLC2 mRNA CTD PMID:22079256 rac-lactic acid decreases expression ISO SPTLC2 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of SPTLC2 mRNA CTD PMID:30851411 resveratrol multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of SPTLC2 mRNA CTD PMID:23557933 SB 431542 multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SPTLC2 mRNA CTD PMID:27188386 sodium fluoride decreases expression ISO Sptlc2 (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of SPTLC2 protein CTD PMID:28918527 tert-butyl hydroperoxide increases expression ISO SPTLC2 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of SPTLC2 mRNA CTD PMID:15336504 testosterone decreases expression ISO SPTLC2 (Homo sapiens) 6480464 Testosterone results in decreased expression of SPTLC2 mRNA CTD PMID:33359661 tetrachloromethane increases expression ISO Sptlc2 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of SPTLC2 mRNA CTD PMID:27339419 and PMID:31919559 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of SPTLC2 mRNA] CTD PMID:31150632 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of SPTLC2 mRNA CTD PMID:31150632 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of SPTLC2 mRNA CTD PMID:23411599 and PMID:34492290 triclocarban increases expression EXP 6480464 triclocarban results in increased expression of SPTLC2 mRNA CTD PMID:31576746 urethane increases expression ISO SPTLC2 (Homo sapiens) 6480464 Urethane results in increased expression of SPTLC2 mRNA CTD PMID:28818685 valproic acid increases expression ISO Sptlc2 (Mus musculus) 6480464 Valproic Acid results in increased expression of SPTLC2 mRNA CTD PMID:21427059 valproic acid increases expression ISO SPTLC2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of SPTLC2 mRNA CTD PMID:23179753 more ... vancomycin decreases expression ISO Sptlc2 (Mus musculus) 6480464 Vancomycin results in decreased expression of SPTLC2 mRNA CTD PMID:18930951 zinc atom multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SPTLC2 mRNA CTD PMID:18593933 zinc(0) multiple interactions ISO SPTLC2 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SPTLC2 mRNA CTD PMID:18593933
