Rgs6 (regulator of G-protein signaling 6) - Rat Genome Database

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Gene: Rgs6 (regulator of G-protein signaling 6) Rattus norvegicus
Analyze
Symbol: Rgs6
Name: regulator of G-protein signaling 6
RGD ID: 3569
Description: Enables protein domain specific binding activity. Involved in positive regulation of neuron differentiation. Located in Golgi apparatus. Part of protein-containing complex. Orthologous to human RGS6 (regulator of G protein signaling 6); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26102,264,451 - 102,796,311 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6102,264,447 - 102,824,753 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6102,420,755 - 102,953,980 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.06102,719,975 - 103,253,217 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.06102,089,444 - 102,622,685 (+)NCBIRnor_WKY
Rnor_6.06106,310,442 - 106,598,668 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6106,496,992 - 106,602,139 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06114,636,387 - 114,736,790 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46106,470,420 - 106,964,581 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16106,940,142 - 106,967,896 (+)NCBI
Celera6100,100,895 - 100,625,650 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Regulators of G-protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain. Gold SJ, etal., J Neurosci 1997 Oct 15;17(20):8024-37.
4. EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins. Koelle MR and Horvitz HR, Cell 1996 Jan 12;84(1):115-25.
5. RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6. Liu Z, etal., J Biol Chem 2002 Oct 4;277(40):37832-9. Epub 2002 Jul 24.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. RGS Proteins in Heart: Brakes on the Vagus. Stewart A, etal., Front Physiol. 2012 Apr 13;3:95. doi: 10.3389/fphys.2012.00095. eCollection 2012.
Additional References at PubMed
PMID:10521509  


Genomics

Comparative Map Data
Rgs6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26102,264,451 - 102,796,311 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6102,264,447 - 102,824,753 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6102,420,755 - 102,953,980 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.06102,719,975 - 103,253,217 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.06102,089,444 - 102,622,685 (+)NCBIRnor_WKY
Rnor_6.06106,310,442 - 106,598,668 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6106,496,992 - 106,602,139 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06114,636,387 - 114,736,790 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46106,470,420 - 106,964,581 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16106,940,142 - 106,967,896 (+)NCBI
Celera6100,100,895 - 100,625,650 (+)NCBICelera
Cytogenetic Map6q24NCBI
RGS6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381471,867,335 - 72,630,029 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1471,932,429 - 72,566,530 (+)EnsemblGRCh38hg38GRCh38
GRCh371472,398,888 - 73,033,238 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361471,469,539 - 72,102,991 (+)NCBINCBI36Build 36hg18NCBI36
Build 341471,469,585 - 72,100,407NCBI
Celera1452,462,976 - 53,096,417 (+)NCBICelera
Cytogenetic Map14q24.2NCBI
HuRef1452,565,478 - 53,199,765 (+)NCBIHuRef
CHM1_11472,336,952 - 72,971,253 (+)NCBICHM1_1
T2T-CHM13v2.01466,137,624 - 66,772,163 (+)NCBIT2T-CHM13v2.0
Rgs6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391282,663,325 - 83,208,835 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1282,635,066 - 83,208,830 (+)EnsemblGRCm39 Ensembl
GRCm381282,616,551 - 83,162,061 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1282,588,292 - 83,162,056 (+)EnsemblGRCm38mm10GRCm38
MGSCv371283,718,025 - 84,259,799 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361283,535,886 - 84,077,669 (+)NCBIMGSCv36mm8
Celera1284,069,722 - 84,604,177 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1238.14NCBI
Rgs6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555232,762,987 - 3,335,474 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555232,763,143 - 3,366,851 (-)NCBIChiLan1.0ChiLan1.0
RGS6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11471,377,567 - 72,012,766 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1471,409,701 - 72,008,988 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01452,511,846 - 53,146,872 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
RGS6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1845,392,246 - 45,975,073 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl845,438,239 - 46,009,049 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha845,077,684 - 45,656,669 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0845,630,187 - 46,197,033 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl845,654,256 - 46,194,458 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1845,301,232 - 45,866,115 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0845,329,999 - 45,882,332 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0845,692,998 - 46,272,644 (+)NCBIUU_Cfam_GSD_1.0
Rgs6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864030,144,323 - 30,732,878 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364881,361,310 - 1,921,353 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049364881,336,075 - 1,924,635 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl795,365,939 - 95,930,034 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1795,365,212 - 95,930,040 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RGS6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12449,161,466 - 49,803,209 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2449,591,815 - 49,775,653 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605337,367,918 - 37,991,218 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473428,829,698 - 29,411,779 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473428,830,254 - 29,436,945 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rgs6
3016 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:62
Count of miRNA genes:56
Interacting mature miRNAs:62
Transcripts:ENSRNOT00000058181
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat

Markers in Region
RH140792  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26102,792,686 - 102,792,927 (+)MAPPERmRatBN7.2
Rnor_6.06106,598,200 - 106,598,440NCBIRnor6.0
Rnor_5.06114,736,322 - 114,736,562UniSTSRnor5.0
RGSC_v3.46106,987,770 - 106,988,010UniSTSRGSC3.4
Celera6100,625,182 - 100,625,422UniSTS
RH 3.4 Map6732.5UniSTS
Cytogenetic Map6q24UniSTS
RH143195  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26102,792,822 - 102,793,075 (+)MAPPERmRatBN7.2
Rnor_6.06106,598,336 - 106,598,588NCBIRnor6.0
Rnor_5.06114,736,458 - 114,736,710UniSTSRnor5.0
RGSC_v3.46106,987,906 - 106,988,158UniSTSRGSC3.4
Celera6100,625,318 - 100,625,570UniSTS
RH 3.4 Map6738.0UniSTS
Cytogenetic Map6q24UniSTS
RH143409  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26102,692,460 - 102,692,712 (+)MAPPERmRatBN7.2
Rnor_6.06106,499,816 - 106,500,067NCBIRnor6.0
Rnor_5.06114,639,079 - 114,639,330UniSTSRnor5.0
RGSC_v3.46106,876,517 - 106,876,768UniSTSRGSC3.4
Celera6100,526,473 - 100,526,724UniSTS
RH 3.4 Map6738.0UniSTS
Cytogenetic Map6q24UniSTS
BF398997  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26102,773,210 - 102,773,402 (+)MAPPERmRatBN7.2
Rnor_6.06106,578,724 - 106,578,915NCBIRnor6.0
Rnor_5.06114,716,846 - 114,717,037UniSTSRnor5.0
RGSC_v3.46106,968,294 - 106,968,485UniSTSRGSC3.4
Celera6100,605,596 - 100,605,787UniSTS
RH 3.4 Map6738.0UniSTS
Cytogenetic Map6q24UniSTS
fc10a03.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26102,616,986 - 102,618,290 (+)MAPPERmRatBN7.2
Rnor_6.06107,944,860 - 107,946,163NCBIRnor6.0
Rnor_5.06117,600,272 - 117,601,576NCBIRnor5.0
RGSC_v3.46106,800,999 - 106,802,302UniSTSRGSC3.4
Celera6100,451,085 - 100,452,388UniSTS
Cytogenetic Map6q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 15 46 3 3
Low 3 28 28 12 19 12 8 10 18 21 38 8 8
Below cutoff 29 29 29 1 10 14

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000058181   ⟹   ENSRNOP00000054984
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,793,155 (+)Ensembl
Rnor_6.0 Ensembl6106,497,125 - 106,598,668 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086136   ⟹   ENSRNOP00000069089
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,693,478 - 102,773,706 (+)Ensembl
Rnor_6.0 Ensembl6106,496,992 - 106,602,139 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095987   ⟹   ENSRNOP00000082201
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,631 - 102,824,753 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100420   ⟹   ENSRNOP00000077898
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,733,221 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103061   ⟹   ENSRNOP00000079796
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,689,770 - 102,770,177 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000107970   ⟹   ENSRNOP00000091378
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,773,304 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109319   ⟹   ENSRNOP00000079945
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,793,132 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112595   ⟹   ENSRNOP00000092991
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,793,132 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113156   ⟹   ENSRNOP00000091512
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,793,132 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114544   ⟹   ENSRNOP00000085795
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6102,264,447 - 102,824,753 (+)Ensembl
RefSeq Acc Id: NM_019342   ⟹   NP_062215
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,265,295 - 102,793,155 (+)NCBI
Rnor_6.06106,310,442 - 106,598,668 (+)NCBI
Rnor_5.06114,636,387 - 114,736,790 (+)NCBI
Celera6100,100,895 - 100,625,650 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039112781   ⟹   XP_038968709
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,293,910 - 102,796,311 (+)NCBI
RefSeq Acc Id: XM_039112782   ⟹   XP_038968710
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,264,823 - 102,796,311 (+)NCBI
RefSeq Acc Id: XM_039112783   ⟹   XP_038968711
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,265,483 - 102,796,311 (+)NCBI
RefSeq Acc Id: XM_039112784   ⟹   XP_038968712
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,265,679 - 102,796,311 (+)NCBI
RefSeq Acc Id: XM_039112785   ⟹   XP_038968713
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,265,264 - 102,796,311 (+)NCBI
RefSeq Acc Id: XM_039112786   ⟹   XP_038968714
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,293,910 - 102,792,342 (+)NCBI
RefSeq Acc Id: XM_039112787   ⟹   XP_038968715
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,293,910 - 102,777,665 (+)NCBI
RefSeq Acc Id: XM_039112788   ⟹   XP_038968716
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,293,910 - 102,796,311 (+)NCBI
RefSeq Acc Id: XM_039112789   ⟹   XP_038968717
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,293,910 - 102,792,406 (+)NCBI
RefSeq Acc Id: XM_039112790   ⟹   XP_038968718
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,293,910 - 102,759,765 (+)NCBI
RefSeq Acc Id: XM_039112791   ⟹   XP_038968719
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,264,451 - 102,796,311 (+)NCBI
RefSeq Acc Id: XR_005505572
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26102,293,910 - 102,792,343 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_062215   ⟸   NM_019342
- UniProtKB: F1LS67 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054984   ⟸   ENSRNOT00000058181
RefSeq Acc Id: ENSRNOP00000069089   ⟸   ENSRNOT00000086136
RefSeq Acc Id: XP_038968719   ⟸   XM_039112791
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G3X7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968710   ⟸   XM_039112782
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G3X7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968713   ⟸   XM_039112785
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G3X7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968711   ⟸   XM_039112783
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G3X7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968712   ⟸   XM_039112784
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G3X7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968716   ⟸   XM_039112788
- Peptide Label: isoform X5
- UniProtKB: A0A8I6GJP9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968709   ⟸   XM_039112781
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038968717   ⟸   XM_039112789
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038968714   ⟸   XM_039112786
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038968715   ⟸   XM_039112787
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038968718   ⟸   XM_039112790
- Peptide Label: isoform X7
RefSeq Acc Id: ENSRNOP00000079796   ⟸   ENSRNOT00000103061
RefSeq Acc Id: ENSRNOP00000079945   ⟸   ENSRNOT00000109319
RefSeq Acc Id: ENSRNOP00000091512   ⟸   ENSRNOT00000113156
RefSeq Acc Id: ENSRNOP00000092991   ⟸   ENSRNOT00000112595
RefSeq Acc Id: ENSRNOP00000091378   ⟸   ENSRNOT00000107970
RefSeq Acc Id: ENSRNOP00000085795   ⟸   ENSRNOT00000114544
RefSeq Acc Id: ENSRNOP00000077898   ⟸   ENSRNOT00000100420
RefSeq Acc Id: ENSRNOP00000082201   ⟸   ENSRNOT00000095987
Protein Domains
DEP   RGS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P49801-F1-model_v2 AlphaFold P49801 1-66 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3569 AgrOrtholog
BioCyc Gene G2FUF-36866 BioCyc
Ensembl Genes ENSRNOG00000008082 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000054984 ENTREZGENE
  ENSRNOP00000054984.5 UniProtKB/TrEMBL
  ENSRNOP00000069089.2 UniProtKB/TrEMBL
  ENSRNOP00000077898.1 UniProtKB/TrEMBL
  ENSRNOP00000079796.1 UniProtKB/TrEMBL
  ENSRNOP00000079945 ENTREZGENE
  ENSRNOP00000079945.1 UniProtKB/TrEMBL
  ENSRNOP00000082201.1 UniProtKB/TrEMBL
  ENSRNOP00000085795.1 UniProtKB/TrEMBL
  ENSRNOP00000091378 ENTREZGENE
  ENSRNOP00000091378.1 UniProtKB/TrEMBL
  ENSRNOP00000091512 ENTREZGENE
  ENSRNOP00000091512.1 UniProtKB/TrEMBL
  ENSRNOP00000092991.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058181 ENTREZGENE
  ENSRNOT00000058181.5 UniProtKB/TrEMBL
  ENSRNOT00000086136 ENTREZGENE
  ENSRNOT00000086136.2 UniProtKB/TrEMBL
  ENSRNOT00000095987.1 UniProtKB/TrEMBL
  ENSRNOT00000100420.1 UniProtKB/TrEMBL
  ENSRNOT00000103061.1 UniProtKB/TrEMBL
  ENSRNOT00000107970 ENTREZGENE
  ENSRNOT00000107970.1 UniProtKB/TrEMBL
  ENSRNOT00000109319 ENTREZGENE
  ENSRNOT00000109319.1 UniProtKB/TrEMBL
  ENSRNOT00000112595.1 UniProtKB/TrEMBL
  ENSRNOT00000113156 ENTREZGENE
  ENSRNOT00000113156.1 UniProtKB/TrEMBL
  ENSRNOT00000114544.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.167.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.196.10 UniProtKB/TrEMBL
  4.10.260.10 UniProtKB/TrEMBL
InterPro DEP_dom UniProtKB/TrEMBL
  G-protein_gamma_dom UniProtKB/TrEMBL
  GGL_sf UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS6_RGS UniProtKB/TrEMBL
  RGS_DHEX UniProtKB/TrEMBL
  RGS_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene 54295 ENTREZGENE
Pfam DEP UniProtKB/TrEMBL
  G-gamma UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_DHEX UniProtKB/TrEMBL
PhenoGen Rgs6 PhenoGen
PRINTS RGSPROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DEP UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DEP UniProtKB/TrEMBL
  GGL UniProtKB/TrEMBL
  RGS UniProtKB/TrEMBL
Superfamily-SCOP G-protein_gamma-like UniProtKB/TrEMBL
  SSF46785 UniProtKB/TrEMBL
  SSF48097 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JUG4_RAT UniProtKB/TrEMBL
  A0A8I5YC31_RAT UniProtKB/TrEMBL
  A0A8I5ZPB7_RAT UniProtKB/TrEMBL
  A0A8I5ZTQ5_RAT UniProtKB/TrEMBL
  A0A8I6A357_RAT UniProtKB/TrEMBL
  A0A8I6AIT2_RAT UniProtKB/TrEMBL
  A0A8I6G3X7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJK3_RAT UniProtKB/TrEMBL
  A0A8I6GJP9 ENTREZGENE, UniProtKB/TrEMBL
  F1LS67 ENTREZGENE, UniProtKB/TrEMBL
  P49801 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Rgs6  regulator of G-protein signaling 6      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction human homolog binds neuronal growth associated protein SCG10 737642