Gene: Hspa2 (heat shock protein family A (Hsp70) member 2) Rattus norvegicus
Analyze
Symbol: Hspa2
Name: heat shock protein family A (Hsp70) member 2
Description: ENCODES a protein that exhibits chaperone binding; tau protein binding; disordered domain specific binding (ortholog); INVOLVED IN male meiosis I (ortholog); male meiotic nuclear division (ortholog); negative regulation of inclusion body assembly (ortholog); PARTICIPATES IN antigen processing and presentation pathway; endocytosis pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Colonic Neoplasms (ortholog); Myocardial Ischemia (ortholog); FOUND IN CatSper complex (ortholog); cell surface (ortholog); cytosol (ortholog); INTERACTS WITH (R)-carnitine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol
AGR Description: Exhibits chaperone binding activity and tau protein binding activity; predicted to be involved in several processes, including cellular response to heat, cellular response to unfolded protein, and gamete generation; predicted to localize to several cellular components, including the CatSper complex, cell surface, and intracellular organelle; orthologous to human HSPA2 (heat shock protein family A (Hsp70) member 2).
Merged Description: Exhibits chaperone binding activity and tau protein binding activity; predicted to be involved in several processes, including cellular response to heat, cellular response to unfolded protein, and gamete generation; predicted to localize to several cellular components, including the CatSper complex, cell surface, and intracellular organelle; orthologous to human HSPA2 (heat shock protein family A (Hsp70) member 2); PARTICIPATES IN antigen processing and presentation pathway; endocytosis pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (R)-carnitine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: heat shock 70kDa protein 2; heat shock protein 2; heat shock protein 70.2; heat shock protein alpha 2; heat shock protein family A (Hsp70) member 2; heat shock protein family A member 2; heat shock-related 70 kDa protein 2; Hspa2; Hspt70; HST; Hst70; MGC93458; testis-specific heat shock protein-related gene hst70
Orthologs:
Homo sapiens (human) : HSPA2 (heat shock protein family A (Hsp70) member 2)  HGNC  Alliance
Mus musculus (house mouse) : Hspa2 (heat shock protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hspa2 (heat shock protein family A (Hsp70) member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : HSPA2 (heat shock protein family A (Hsp70) member 2)
Canis lupus familiaris (dog) : HSPA2 (heat shock protein family A (Hsp70) member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hspa2 (heat shock protein family A (Hsp70) member 2)
Sus scrofa (pig) : HSPA2 (heat shock protein family A (Hsp70) member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0699,433,575 - 99,436,288 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06108,843,592 - 108,846,304 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4699,000,541 - 99,003,041 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1699,003,760 - 99,006,497 (+)NCBI
Celera693,553,144 - 93,555,644 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hspa2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620664
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.