EZR (ezrin) - Rat Genome Database

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Gene: EZR (ezrin) Homo sapiens
Analyze
Symbol: EZR
Name: ezrin
RGD ID: 1350208
HGNC Page HGNC:12691
Description: Enables several functions, including ATPase binding activity; cytoskeletal protein binding activity; and protein kinase A binding activity. Involved in several processes, including cytoskeleton organization; negative regulation of signal transduction; and regulation of macromolecule metabolic process. Located in several cellular components, including fibrillar center; focal adhesion; and immunological synapse. Part of protein-containing complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CVIL; CVL; cytovillin 2; DKFZp762H157; epididymis secretory protein Li 105; FLJ26216; HEL-S-105; MGC1584; p81; VIL2; villin 2 (ezrin); villin-2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: EZRP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386158,765,748 - 158,819,368 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6158,765,741 - 158,819,368 (-)EnsemblGRCh38hg38GRCh38
GRCh376159,186,780 - 159,240,400 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366159,106,764 - 159,159,247 (-)NCBINCBI36Build 36hg18NCBI36
Build 346159,157,186 - 159,209,668NCBI
Celera6159,834,789 - 159,888,323 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6156,657,307 - 156,711,123 (-)NCBIHuRef
CHM1_16159,449,491 - 159,503,058 (-)NCBICHM1_1
T2T-CHM13v2.06160,010,984 - 160,064,812 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EZRHuman3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome  IAGPRGD:1564507378554872ClinVar Annotator: match by term: 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndromeClinVarPMID:15220921|PMID:22683713|PMID:26863999|PMID:28492532
EZRHumanchromosome 6q24-q25 deletion syndrome  IAGPRGD:4052593728554872ClinVar Annotator: match by term: Chromosome 6q24-q25 deletion syndromeClinVarPMID:25741868|PMID:38177409
EZRHumanprimary ciliary dyskinesia 32  IAGPRGD:1518208668554872ClinVar Annotator: match by term: Primary ciliary dyskinesia 32ClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
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Source
Original Reference(s)
EZRHumanAnimal Mammary Neoplasms  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:12376462
EZRHumancarcinoma  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:12376462
EZRHumanExperimental Liver Cirrhosis  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136
EZRHumanExperimental Mammary Neoplasms  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:12376462
EZRHumanNeoplasm Metastasis  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:27137931
EZRHumanosteoarthritis  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:18784066
EZRHumanProstatic Neoplasms  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:17013881|PMID:17566973|PMID:24763052

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Object Symbol
Species
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Original Reference(s)
EZRHuman(+)-pilocarpine increases expressionISORGD:6211616480464Pilocarpine results in increased expression of EZR proteinCTDPMID:17366478
EZRHuman(S)-amphetamine multiple interactionsISORGD:7324476480464SOD1 inhibits the reaction [Dextroamphetamine results in increased expression of EZR mRNA]CTDPMID:12205029
EZRHuman(S)-amphetamine increases expressionISORGD:7324476480464Dextroamphetamine results in increased expression of EZR mRNACTDPMID:12205029
EZRHuman(S)-nicotine increases expressionEXP 6480464Nicotine results in increased expression of EZR mRNACTDPMID:18247414
EZRHuman(S)-nicotine multiple interactionsISORGD:7324476480464[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of EZR mRNA; Nicotine inhibits the reaction more ...CTDPMID:20230807
EZRHuman1,2-dichloroethane decreases expressionISORGD:7324476480464ethylene dichloride results in decreased expression of EZR mRNACTDPMID:28960355
EZRHuman1,2-dimethylhydrazine multiple interactionsISORGD:7324476480464[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of EZR mRNACTDPMID:22206623
EZRHuman1,2-dimethylhydrazine decreases expressionISORGD:73244764804641,2-Dimethylhydrazine results in decreased expression of EZR mRNACTDPMID:22206623
EZRHuman1,8-cineole multiple interactionsISORGD:7324476480464Eucalyptol inhibits the reaction [Glucose results in decreased expression of EZR protein]; Eucalyptol inhibits the more ...CTDPMID:31483951
EZRHuman1-chloro-2,4-dinitrobenzene affects bindingEXP 6480464Dinitrochlorobenzene binds to EZR proteinCTDPMID:32991956
EZRHuman1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactionsISORGD:7324476480464[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of EZR mRNA; [Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] more ...CTDPMID:20230807
EZRHuman1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expressionISORGD:73244764804641-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of EZR mRNACTDPMID:20230807
EZRHuman1-naphthyl isothiocyanate increases expressionISORGD:62116164804641-Naphthylisothiocyanate results in increased expression of EZR mRNACTDPMID:25380136
EZRHuman17alpha-ethynylestradiol affects expressionISORGD:7324476480464Ethinyl Estradiol affects the expression of EZR mRNACTDPMID:17555576
EZRHuman17alpha-ethynylestradiol decreases expressionISORGD:6211616480464Ethinyl Estradiol results in decreased expression of EZR mRNACTDPMID:29097150
EZRHuman17alpha-ethynylestradiol increases expressionISORGD:6211616480464Ethinyl Estradiol results in increased expression of EZR mRNACTDPMID:17108234|PMID:17557909
EZRHuman17beta-estradiol increases expressionISORGD:7324476480464Estradiol results in increased expression of EZR mRNACTDPMID:15289156|PMID:39298647
EZRHuman17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of EZR mRNA; Estradiol results in increased expression of EZR more ...CTDPMID:15737688|PMID:19167446
EZRHuman17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactionsEXP 6480464bicalutamide inhibits the reaction [Metribolone results in increased expression of EZR mRNA]; bicalutamide inhibits the more ...CTDPMID:16873375
EZRHuman17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases phosphorylationEXP 6480464Metribolone results in increased phosphorylation of EZR proteinCTDPMID:16873375

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Biological Process
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Original Reference(s)
EZRHumanactin cytoskeleton organization involved_inIMP 150520179 PMID:23106337UniProtPMID:23106337
EZRHumanactin filament bundle assembly involved_inIDA 150520179 PMID:10793131UniProtPMID:10793131
EZRHumanastral microtubule organization involved_inIMP 150520179 PMID:20551903UniProtPMID:20551903
EZRHumancellular response to cAMP involved_inIMP 150520179 PMID:17911601UniProtPMID:17911601
EZRHumancortical microtubule organization involved_inIMP 150520179 PMID:20551903UniProtPMID:20551903
EZRHumanepithelial cell differentiation  ISORGD:6211619068941 RGDPMID:7640303|REF_RGD_ID:729995
EZRHumanestablishment of centrosome localization involved_inIMP 150520179 PMID:20551903UniProtPMID:20551903
EZRHumanestablishment of endothelial barrier involved_inIGIUniProtKB:P26038|UniProtKB:P35241150520179 PMID:23264465UniProtPMID:23264465
EZRHumanestablishment of epithelial cell apical/basal polarity NOT|involved_inIMP 150520179 PMID:22797597, PMID:24862762UniProtPMID:22797597|PMID:24862762
EZRHumanestablishment or maintenance of apical/basal cell polarity acts_upstream_of_or_withinIEAUniProtKB:P26040|ensembl:ENSMUSP00000063734150520179 EnsemblGO_REF:0000107
EZRHumanfilopodium assembly  ISORGD:6211619068941 RGDPMID:21753079|REF_RGD_ID:7207797
EZRHumanfilopodium assembly involved_inIMP 150520179 PMID:23106337UniProtPMID:23106337
EZRHumangland morphogenesis NOT|involved_inIMP 150520179 PMID:24862762UniProtPMID:24862762
EZRHumanintestinal D-glucose absorption involved_inIEAUniProtKB:P26040|ensembl:ENSMUSP00000063734150520179 EnsemblGO_REF:0000107
EZRHumanleukocyte cell-cell adhesion involved_inIEP 150520179 PMID:12082081BHF-UCLPMID:12082081
EZRHumanmembrane to membrane docking involved_inIEP 150520179 PMID:12082081BHF-UCLPMID:12082081
EZRHumanmicrovillus assembly NOT|involved_inISOUniProtKB:Q3V0K9|UniProtKB:Q624689068941 PMID:22114352UniProtPMID:22114352
EZRHumanmicrovillus assembly involved_inIMP 150520179 PMID:22797597UniProtPMID:22797597
EZRHumannegative regulation of ERK1 and ERK2 cascade involved_inIMP 150520179 PMID:20551903UniProtPMID:20551903
EZRHumannegative regulation of interleukin-2 production involved_inIMP 150520179 PMID:17911601UniProtPMID:17911601
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Cellular Component
1 to 20 of 62 rows

  
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Original Reference(s)
EZRHumanactin cytoskeleton located_inIDA 150520179 PMID:10793131UniProtPMID:10793131
EZRHumanactin filament located_inIDA 150520179 PMID:11598191HGNC-UCLPMID:11598191
EZRHumanadherens junction is_active_inIBAFB:FBgn0011661|FB:FBgn0086384|MGI:97307|PANTHER:PTN000589933|RGD:1359472150520179 GO_CentralGO_REF:0000033
EZRHumanapical part of cell located_inIDA 150520179 PMID:12082081BHF-UCLPMID:12082081
EZRHumanapical part of cell is_active_inIBAFB:FBgn0011661|FB:FBgn0086384|MGI:97167|MGI:97307|MGI:97887|MGI:98931|PANTHER:PTN000589933|RGD:621161|UniProtKB:P15311|UniProtKB:P26038|UniProtKB:P35241|WB:WBGene00001333150520179 GO_CentralGO_REF:0000033
EZRHumanapical part of cell located_inIEAUniProtKB:P26040|ensembl:ENSMUSP00000063734150520179 EnsemblGO_REF:0000107
EZRHumanapical plasma membrane  ISORGD:6211619068941 RGDPMID:11461930|REF_RGD_ID:7207839
EZRHumanapical plasma membrane located_inIDA 150520179 PMID:17825285, PMID:22797597, PMID:24862762UniProtPMID:17825285|PMID:22797597|PMID:24862762
EZRHumanapical plasma membrane located_inIEAUniProtKB-SubCell:SL-0015150520179 UniProtGO_REF:0000044
EZRHumanapical plasma membrane located_inIEAUniProtKB:P26040|ensembl:ENSMUSP00000063734150520179 EnsemblGO_REF:0000107
EZRHumanastrocyte projection  ISORGD:6211619068941 RGDPMID:21753079|REF_RGD_ID:7207797
EZRHumanbasolateral plasma membrane located_inISSUniProtKB:P31977150520179 UniProtGO_REF:0000024
EZRHumanbrush border located_inIEAUniProtKB:P26040|ensembl:ENSMUSP00000063734150520179 EnsemblGO_REF:0000107
EZRHumanbrush border located_inISSUniProtKB:P26040150520179 UniProtGO_REF:0000024
EZRHumancell body  ISORGD:6211619068941 RGDPMID:11461930|REF_RGD_ID:7207839
EZRHumancell cortex located_inIEAUniProtKB-SubCell:SL-0138150520179 UniProtGO_REF:0000044
EZRHumancell periphery located_inIDA 150520179 PMID:22291017UniProtPMID:22291017
EZRHumancell projection located_inIDA 150520179 PMID:25889165UniProtPMID:25889165
EZRHumancell projection located_inIEAUniProtKB-SubCell:SL-0280150520179 UniProtGO_REF:0000044
EZRHumancell projection located_inIEAUniProtKB-KW:KW-0966150520179 UniProtGO_REF:0000043
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Molecular Function
1 to 20 of 54 rows

  
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Reference
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Original Reference(s)
EZRHumanactin binding enablesIEAInterPro:IPR008954|InterPro:IPR011174150520179 InterProGO_REF:0000002
EZRHumanactin binding enablesIBAFB:FBgn0011661|PANTHER:PTN001150648|RGD:1359472|RGD:621260|UniProtKB:P15311|UniProtKB:P35241150520179 GO_CentralGO_REF:0000033
EZRHumanactin binding enablesIDA 150520179 PMID:17825285UniProtPMID:17825285
EZRHumanactin filament binding enablesIDA 150520179 PMID:10793131UniProtPMID:10793131
EZRHumanATPase binding enablesIPIUniProtKB:Q92887150520179 PMID:17825285UniProtPMID:17825285
EZRHumancadherin binding enablesHDA 150520179 PMID:25468996BHF-UCLPMID:25468996
EZRHumancell adhesion molecule binding enablesIPIUniProtKB:P16278150520179 PMID:15498789BHF-UCLPMID:15498789
EZRHumancell adhesion molecule binding enablesIBAPANTHER:PTN001150648|RGD:3169|UniProtKB:P15311|UniProtKB:P26038150520179 GO_CentralGO_REF:0000033
EZRHumancell adhesion molecule binding enablesIPIUniProtKB:P19320|UniProtKB:P32942150520179 PMID:12082081BHF-UCLPMID:12082081
EZRHumancytoskeletal protein binding enablesIEAInterPro:IPR000798150520179 InterProGO_REF:0000002
EZRHumandisordered domain specific binding enablesIEAUniProtKB:P26040|ensembl:ENSMUSP00000063734150520179 EnsemblGO_REF:0000107
EZRHumanidentical protein binding enablesIPIUniProtKB:P15311150520179 PMID:21988832, PMID:29568061, PMID:31837246IntActPMID:21988832|PMID:29568061|PMID:31837246
EZRHumanmicrotubule binding enablesIMP 150520179 PMID:23857773UniProtPMID:23857773
EZRHumanprotein binding  ISORGD:29989068941 RGDPMID:15044370|REF_RGD_ID:1581827
EZRHumanprotein binding enablesIPIUniProtKB:Q8IZU9150520179 PMID:34799561IntActPMID:34799561
EZRHumanprotein binding enablesIPIUniProtKB:Q8IZE3150520179 PMID:12651155, PMID:32707033IntActPMID:12651155|PMID:32707033
EZRHumanprotein binding enablesIPIUniProtKB:P07384150520179 PMID:22805611IntActPMID:22805611
EZRHumanprotein binding enablesIPIUniProtKB:P07332150520179 PMID:18046454IntActPMID:18046454
EZRHumanprotein binding enablesIPIUniProtKB:Q8IVT2150520179 PMID:28514442, PMID:32296183IntActPMID:28514442|PMID:32296183
EZRHumanprotein binding enablesIPIUniProtKB:O14745150520179 PMID:15020681, PMID:20937695IntActPMID:15020681|PMID:20937695
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RGD Manual Annotations


  
Object Symbol
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Reference
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Source
Original Reference(s)
EZRHumanparathyroid hormone signaling pathway   TAS 7207465 RGD 
EZRHumanprotein kinase A (PKA) signaling pathway   TAS 2312475 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EZRHumanpathogenic Escherichia coli infection pathway  IEA 6907045 KEGGhsa:05130

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EZRHumanFasL mediated signaling pathway   EXP 6484113 PIDPID:200080
EZRHumansyndecan signaling pathway  EXP 6484113 PIDPID:200192

#
Reference Title
Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. The parathyroid hormone receptorsome and the potential for therapeutic intervention. Mahon MJ Curr Drug Targets. 2012 Jan;13(1):116-28.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Localized effects of cAMP mediated by distinct routes of protein kinase A. Tasken K and Aandahl EM, Physiol Rev. 2004 Jan;84(1):137-67.
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PMID:1159819   PMID:1381389   PMID:1382070   PMID:1762625   PMID:1924289   PMID:2591371   PMID:2592436   PMID:2674140   PMID:7579708   PMID:7844168   PMID:7876308   PMID:8089177  
PMID:8162705   PMID:8248180   PMID:8713105   PMID:8892894   PMID:9009265   PMID:9213396   PMID:9287351   PMID:9314537   PMID:9501018   PMID:9616160   PMID:9705328   PMID:9748260  
PMID:9852149   PMID:9921900   PMID:9928947   PMID:10036239   PMID:10377409   PMID:10462524   PMID:10704377   PMID:10713718   PMID:10733515   PMID:10793131   PMID:10799517   PMID:10806479  
PMID:10893422   PMID:10955717   PMID:10970850   PMID:11013215   PMID:11285285   PMID:11387207   PMID:11438984   PMID:11468295   PMID:11598191   PMID:11684085   PMID:11706008   PMID:11726633  
PMID:11784723   PMID:12032545   PMID:12070130   PMID:12080047   PMID:12082080   PMID:12082081   PMID:12111362   PMID:12154370   PMID:12271120   PMID:12360288   PMID:12370738   PMID:12385025  
PMID:12387735   PMID:12429733   PMID:12477932   PMID:12560083   PMID:12626536   PMID:12651155   PMID:12711360   PMID:12734202   PMID:12769842   PMID:12800220   PMID:12808036   PMID:12860416  
PMID:14574404   PMID:14625392   PMID:14676203   PMID:14704789   PMID:14704791   PMID:14739941   PMID:14981079   PMID:15020681   PMID:15096511   PMID:15149851   PMID:15178693   PMID:15252013  
PMID:15489334   PMID:15498789   PMID:15531580   PMID:15623525   PMID:15647376   PMID:15659383   PMID:15677456   PMID:15729356   PMID:15751968   PMID:15797715   PMID:15818415   PMID:15835821  
PMID:15843435   PMID:16009940   PMID:16129695   PMID:16144921   PMID:16230228   PMID:16344560   PMID:16352594   PMID:16438931   PMID:16502470   PMID:16538541   PMID:16554733   PMID:16633060  
PMID:16648854   PMID:16677779   PMID:16737952   PMID:16867268   PMID:16873375   PMID:16889625   PMID:17028919   PMID:17046996   PMID:17159908   PMID:17237445   PMID:17242191   PMID:17349711  
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EZR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386158,765,748 - 158,819,368 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6158,765,741 - 158,819,368 (-)EnsemblGRCh38hg38GRCh38
GRCh376159,186,780 - 159,240,400 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366159,106,764 - 159,159,247 (-)NCBINCBI36Build 36hg18NCBI36
Build 346159,157,186 - 159,209,668NCBI
Celera6159,834,789 - 159,888,323 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6156,657,307 - 156,711,123 (-)NCBIHuRef
CHM1_16159,449,491 - 159,503,058 (-)NCBICHM1_1
T2T-CHM13v2.06160,010,984 - 160,064,812 (-)NCBIT2T-CHM13v2.0
Ezr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39177,005,530 - 7,050,179 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl177,005,440 - 7,050,183 (-)EnsemblGRCm39 Ensembl
GRCm38176,738,131 - 6,782,780 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl176,738,041 - 6,782,784 (-)EnsemblGRCm38mm10GRCm38
MGSCv37176,942,480 - 6,987,129 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36176,587,789 - 6,632,438 (-)NCBIMGSCv36mm8
Celera1514,687,905 - 14,732,667 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map174.38NCBI
Ezr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,373,033 - 49,416,573 (-)NCBIGRCr8
mRatBN7.2146,967,961 - 47,011,505 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,967,658 - 47,011,505 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx147,516,906 - 47,560,444 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,504,177 - 53,547,825 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,592,352 - 47,635,890 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,287,872 - 47,331,412 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,287,874 - 47,331,412 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,590,971 - 48,634,511 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,178,195 - 41,221,735 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1141,181,139 - 41,224,680 (-)NCBI
Celera142,655,531 - 42,699,079 (-)NCBICelera
Cytogenetic Map1q11NCBI
Ezr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554393,703,013 - 3,740,345 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554393,701,722 - 3,740,345 (+)NCBIChiLan1.0ChiLan1.0
EZR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25178,869,668 - 178,923,683 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16176,774,286 - 176,828,291 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06156,656,146 - 156,709,986 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16161,670,483 - 161,723,102 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6161,670,483 - 161,723,102 (-)Ensemblpanpan1.1panPan2
EZR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,160,206 - 48,210,036 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,160,206 - 48,210,036 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha149,005,197 - 49,055,099 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0148,346,325 - 48,397,738 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl148,346,327 - 48,397,690 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1148,223,100 - 48,272,944 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0148,093,979 - 48,143,792 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,653,395 - 48,703,265 (-)NCBIUU_Cfam_GSD_1.0
Ezr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,161,383 - 143,205,800 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648910,412,710 - 10,458,201 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648910,413,374 - 10,457,771 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EZR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18,403,453 - 8,452,742 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118,403,362 - 8,452,750 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2110,423,530 - 10,432,162 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EZR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11386,342,954 - 86,399,827 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1386,344,051 - 86,370,622 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604058,721,321 - 58,778,578 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ezr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624929826,531 - 873,572 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624929827,275 - 873,743 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in EZR
84 total Variants

1 to 10 of 122 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 6q24.1-27(chr6:141132990-169339571)x3 copy number gain See cases [RCV000050604] Chr6:141132990..169339571 [GRCh38]
Chr6:141454127..169739666 [GRCh37]
Chr6:141495820..169481591 [NCBI36]
Chr6:6q24.1-27
pathogenic
GRCh38/hg38 6q25.2-27(chr6:152376338-170583214)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051902]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051902]|See cases [RCV000051902] Chr6:152376338..170583214 [GRCh38]
Chr6:152697473..170892302 [GRCh37]
Chr6:152739166..170734227 [NCBI36]
Chr6:6q25.2-27
pathogenic
GRCh38/hg38 6q25.3(chr6:157827805-159726548)x3 copy number gain See cases [RCV000051903] Chr6:157827805..159726548 [GRCh38]
Chr6:158248837..160147580 [GRCh37]
Chr6:158168825..160067570 [NCBI36]
Chr6:6q25.3
pathogenic
GRCh38/hg38 6q25.3-27(chr6:158664768-170612001)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051904]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051904]|See cases [RCV000051904] Chr6:158664768..170612001 [GRCh38]
Chr6:159085800..170921089 [GRCh37]
Chr6:159005788..170763014 [NCBI36]
Chr6:6q25.3-27
pathogenic
GRCh38/hg38 6q25.2-27(chr6:154118058-170602152)x1 copy number loss See cases [RCV000052207] Chr6:154118058..170602152 [GRCh38]
Chr6:154439193..170911240 [GRCh37]
Chr6:154480885..170753165 [NCBI36]
Chr6:6q25.2-27
pathogenic
GRCh38/hg38 6q25.2-25.3(chr6:154178964-159020369)x1 copy number loss See cases [RCV000134896] Chr6:154178964..159020369 [GRCh38]
Chr6:154500098..159441401 [GRCh37]
Chr6:154541790..159361389 [NCBI36]
Chr6:6q25.2-25.3
likely pathogenic
GRCh38/hg38 6q25.2-27(chr6:154539655-170714507)x1 copy number loss See cases [RCV000137381] Chr6:154539655..170714507 [GRCh38]
Chr6:154860789..171023595 [GRCh37]
Chr6:154902481..170865520 [NCBI36]
Chr6:6q25.2-27
pathogenic
GRCh38/hg38 6q25.3-26(chr6:155378049-163133499)x1 copy number loss See cases [RCV000137831] Chr6:155378049..163133499 [GRCh38]
Chr6:155699183..163554531 [GRCh37]
Chr6:155740875..163474521 [NCBI36]
Chr6:6q25.3-26
pathogenic
GRCh38/hg38 6q25.1-25.3(chr6:150381239-159553952)x1 copy number loss See cases [RCV000139578] Chr6:150381239..159553952 [GRCh38]
Chr6:150702375..159974984 [GRCh37]
Chr6:150744068..159894974 [NCBI36]
Chr6:6q25.1-25.3
pathogenic
GRCh38/hg38 6q25.2-27(chr6:152793402-170610394)x1 copy number loss See cases [RCV000141880] Chr6:152793402..170610394 [GRCh38]
Chr6:153114537..170919482 [GRCh37]
Chr6:153156230..170761407 [NCBI36]
Chr6:6q25.2-27
pathogenic
1 to 10 of 122 rows

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR183hsa-miR-183-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI18840437
MIR183hsa-miR-183-5pMirecordsexternal_info{unchanged}NA18840437
MIR183hsa-miR-183-5pOncomiRDBexternal_infoNANA22922800
MIR183hsa-miR-183-5pOncomiRDBexternal_infoNANA22525461
MIR183hsa-miR-183-5pOncomiRDBexternal_infoNANA18840437
MIR204hsa-miR-204-5pMirtarbaseexternal_infoImmunoblot//Luciferase reporter assayFunctional MTI21416062
MIR204hsa-miR-204-5pOncomiRDBexternal_infoNANA21416062

Predicted Target Of
Summary Value
Count of predictions:1415
Count of miRNA genes:669
Interacting mature miRNAs:748
Transcripts:ENST00000337147, ENST00000367075, ENST00000392177, ENST00000476189
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
407092675GWAS741651_Hhair color QTL GWAS741651 (human)9e-55hair color6158770756158770757Human
597342174GWAS1438248_Hserum alanine aminotransferase measurement QTL GWAS1438248 (human)1e-12serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)6158809601158809602Human
1643404BMD3_HBone mineral density QTL 3 (human)2.420.0005Bone mineral density6157563614170805979Human
597097180GWAS1193254_Htestosterone measurement QTL GWAS1193254 (human)2e-09testosterone measurementserum testosterone level (CMO:0000568)6158803529158803530Human
597169700GWAS1265774_Hserum alanine aminotransferase measurement QTL GWAS1265774 (human)8e-11serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)6158802736158802737Human
1643367BW323_HBody weight QTL 323 (human)2.420.0005Body fat amount6157563614170805979Human

D6S1614  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376159,195,681 - 159,195,765UniSTSGRCh37
Build 366159,115,669 - 159,115,753RGDNCBI36
Celera6159,843,691 - 159,843,765RGD
Cytogenetic Map6q25.3UniSTS
HuRef6156,666,209 - 156,666,283UniSTS
Marshfield Genetic Map6159.98RGD
Marshfield Genetic Map6159.98UniSTS
Genethon Genetic Map6161.2UniSTS
RH46601  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376159,186,795 - 159,186,951UniSTSGRCh37
Build 366159,106,783 - 159,106,939RGDNCBI36
Celera6159,834,811 - 159,834,967RGD
Cytogenetic Map6q25.3UniSTS
HuRef6156,657,329 - 156,657,485UniSTS
GeneMap99-GB4 RH Map6621.6UniSTS
NCBI RH Map61625.9UniSTS
RH91385  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376159,206,406 - 159,206,542UniSTSGRCh37
Build 366159,126,394 - 159,126,530RGDNCBI36
Celera6159,854,408 - 159,854,544RGD
Cytogenetic Map6q25.3UniSTS
HuRef6156,677,263 - 156,677,399UniSTS
GeneMap99-GB4 RH Map6619.71UniSTS
RH27492  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376159,187,133 - 159,187,201UniSTSGRCh37
Build 366159,107,121 - 159,107,189RGDNCBI36
Celera6159,835,145 - 159,835,213RGD
Cytogenetic Map6q25.3UniSTS
HuRef6156,657,663 - 156,657,731UniSTS
SHGC-149418  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376159,208,750 - 159,209,047UniSTSGRCh37
Build 366159,128,738 - 159,129,035RGDNCBI36
Celera6159,856,753 - 159,857,050RGD
Cytogenetic Map6q25.3UniSTS
HuRef6156,679,608 - 156,679,905UniSTS
TNG Radiation Hybrid Map678956.0UniSTS
D15S1323  
Human AssemblyChrPosition (strand)SourceJBrowse
Celera6159,835,662 - 159,835,897RGD
Cytogenetic Map6q25.3UniSTS
HuRef6156,658,180 - 156,658,415UniSTS
GeneMap99-G3 RH Map35081.0UniSTS
SHGC-30156  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376159,186,792 - 159,186,916UniSTSGRCh37
Build 366159,106,780 - 159,106,904RGDNCBI36
Celera6159,834,808 - 159,834,932RGD
Cytogenetic Map6q25.3UniSTS
HuRef6156,657,326 - 156,657,450UniSTS
GeneMap99-GB4 RH Map6621.6UniSTS
Whitehead-RH Map6829.0UniSTS
NCBI RH Map61633.8UniSTS
GeneMap99-G3 RH Map66551.0UniSTS
SHGC-146276  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6q25.3UniSTS
HuRef6156,673,307 - 156,673,647UniSTS
TNG Radiation Hybrid Map678942.0UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1


1 to 29 of 29 rows
RefSeq Transcripts NG_052952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001111077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011536110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054356313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF187552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF188896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF188897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF189213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF190059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF199015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI366687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL162086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL589931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC013903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA754543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA783190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF184645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ224318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J05021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X51521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 29 of 29 rows

Ensembl Acc Id: ENST00000337147   ⟹   ENSP00000338934
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,765,741 - 158,818,227 (-)Ensembl
Ensembl Acc Id: ENST00000367075   ⟹   ENSP00000356042
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,765,748 - 158,819,368 (-)Ensembl
Ensembl Acc Id: ENST00000392177   ⟹   ENSP00000376016
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,765,742 - 158,789,474 (-)Ensembl
Ensembl Acc Id: ENST00000476189
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,783,534 - 158,819,349 (-)Ensembl
RefSeq Acc Id: NM_001111077   ⟹   NP_001104547
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,765,748 - 158,819,368 (-)NCBI
GRCh376159,186,773 - 159,240,456 (-)ENTREZGENE
HuRef6156,657,307 - 156,711,123 (-)ENTREZGENE
CHM1_16159,449,491 - 159,503,058 (-)NCBI
T2T-CHM13v2.06160,010,984 - 160,064,812 (-)NCBI
Sequence:
RefSeq Acc Id: NM_003379   ⟹   NP_003370
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,765,748 - 158,818,235 (-)NCBI
GRCh376159,186,773 - 159,240,456 (-)ENTREZGENE
Build 366159,106,764 - 159,159,247 (-)NCBI Archive
HuRef6156,657,307 - 156,711,123 (-)ENTREZGENE
CHM1_16159,449,491 - 159,501,942 (-)NCBI
T2T-CHM13v2.06160,010,984 - 160,063,679 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011536110   ⟹   XP_011534412
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,765,748 - 158,789,346 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054356313   ⟹   XP_054212288
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.06160,010,984 - 160,034,914 (-)NCBI
RefSeq Acc Id: NP_001104547   ⟸   NM_001111077
- UniProtKB: Q96CU8 (UniProtKB/Swiss-Prot),   Q4VX75 (UniProtKB/Swiss-Prot),   P23714 (UniProtKB/Swiss-Prot),   E1P5A8 (UniProtKB/Swiss-Prot),   Q9NSJ4 (UniProtKB/Swiss-Prot),   P15311 (UniProtKB/Swiss-Prot),   B2R6J2 (UniProtKB/TrEMBL),   V9HW42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_003370   ⟸   NM_003379
- UniProtKB: Q96CU8 (UniProtKB/Swiss-Prot),   Q4VX75 (UniProtKB/Swiss-Prot),   P23714 (UniProtKB/Swiss-Prot),   E1P5A8 (UniProtKB/Swiss-Prot),   Q9NSJ4 (UniProtKB/Swiss-Prot),   P15311 (UniProtKB/Swiss-Prot),   B2R6J2 (UniProtKB/TrEMBL),   V9HW42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011534412   ⟸   XM_011536110
- Peptide Label: isoform X1
- UniProtKB: B7Z437 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000338934   ⟸   ENST00000337147
Ensembl Acc Id: ENSP00000356042   ⟸   ENST00000367075
FERM

Name Modeler Protein Id AA Range Protein Structure
AF-P15311-F1-model_v2 AlphaFold P15311 1-586 view protein structure

RGD ID:7209561
Promoter ID:EPDNEW_H10526
Type:initiation region
Name:EZR_2
Description:ezrin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H10527  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,818,235 - 158,818,295EPDNEW
RGD ID:7209563
Promoter ID:EPDNEW_H10527
Type:initiation region
Name:EZR_1
Description:ezrin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H10526  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,819,364 - 158,819,424EPDNEW
RGD ID:6804005
Promoter ID:HG_KWN:55624
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour,   Lymphoblastoid
Transcripts:ENST00000367074,   ENST00000392177
Position:
Human AssemblyChrPosition (strand)Source
Build 366159,130,149 - 159,130,649 (-)MPROMDB
RGD ID:6804214
Promoter ID:HG_KWN:55627
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_003379
Position:
Human AssemblyChrPosition (strand)Source
Build 366159,159,151 - 159,160,287 (-)MPROMDB
RGD ID:6804215
Promoter ID:HG_KWN:55628
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001111077,   OTTHUMT00000042880
Position:
Human AssemblyChrPosition (strand)Source
Build 366159,160,199 - 159,160,699 (-)MPROMDB


1 to 40 of 67 rows
Database
Acc Id
Source(s)
COSMIC EZR COSMIC
Ensembl Genes ENSG00000092820 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000337147 ENTREZGENE
  ENST00000337147.11 UniProtKB/Swiss-Prot
  ENST00000367075 ENTREZGENE
  ENST00000367075.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.450 UniProtKB/Swiss-Prot
  1.20.80.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  6.10.360.10 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
GTEx ENSG00000092820 GTEx
HGNC ID HGNC:12691 ENTREZGENE
Human Proteome Map EZR Human Proteome Map
InterPro Band_41_domain UniProtKB/Swiss-Prot
  ERM UniProtKB/Swiss-Prot
  ERM_C_dom UniProtKB/Swiss-Prot
  ERM_FERM_C UniProtKB/Swiss-Prot
  ERM_helical UniProtKB/Swiss-Prot
  Ez/rad/moesin-like UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_central UniProtKB/Swiss-Prot
  FERM_CS UniProtKB/Swiss-Prot
  FERM_domain UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  FERM_PH-like_C UniProtKB/Swiss-Prot
  Moesin_tail_sf UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
KEGG Report hsa:7430 UniProtKB/Swiss-Prot
NCBI Gene 7430 ENTREZGENE
OMIM 123900 OMIM
PANTHER PTHR23281 UniProtKB/Swiss-Prot
Pfam ERM_C UniProtKB/Swiss-Prot
  ERM_helical UniProtKB/Swiss-Prot
  FERM_C UniProtKB/Swiss-Prot
  FERM_M UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
PharmGKB PA162385512 PharmGKB
1 to 40 of 67 rows