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Gene: Ezr (ezrin) Rattus norvegicus
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Symbol: Ezr
Name: ezrin
Description: Exhibits protein domain specific binding activity. Involved in epithelial cell differentiation and filopodium assembly. Localizes to several cellular components, including the T-tubule; actin-based cell projection; and microspike. Predicted to colocalize with the focal adhesion and immunological synapse. Orthologous to human EZR (ezrin); PARTICIPATES IN FasL mediated signaling pathway; parathyroid hormone signaling pathway; protein kinase A (PKA) signaling pathway; INTERACTS WITH (+)-pilocarpine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cytovillin; MGC94076; p81; Vil2; villin 2; villin-2
Orthologs:
Homo sapiens (human) : EZR (ezrin)  HGNC  Alliance
Mus musculus (house mouse) : Ezr (ezrin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ezr (ezrin)
Pan paniscus (bonobo/pygmy chimpanzee) : EZR (ezrin)
Canis lupus familiaris (dog) : EZR (ezrin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ezr (ezrin)
Sus scrofa (pig) : EZR (ezrin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0147,287,872 - 47,331,412 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0148,590,971 - 48,634,511 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,178,195 - 41,221,735 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1141,181,139 - 41,224,680 (-)NCBI
Celera142,655,531 - 42,699,079 (-)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ezr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621161
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-06-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.