Hspa2 (heat shock protein family A (Hsp70) member 2) - Rat Genome Database

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Gene: Hspa2 (heat shock protein family A (Hsp70) member 2) Heterocephalus glaber
Analyze
Symbol: Hspa2
Name: heat shock protein family A (Hsp70) member 2
RGD ID: 18920422
Description: ENCODES a protein that exhibits protein-folding chaperone binding (ortholog); tau protein binding (ortholog); INVOLVED IN male meiosis I (ortholog); male meiotic nuclear division (ortholog); positive regulation of ATP-dependent activity (ortholog); ASSOCIATED WITH Colonic Neoplasms (ortholog); Myocardial Ischemia (ortholog); FOUND IN CatSper complex (inferred); cell surface (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: heat shock-related 70 kDa protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473436,476,372 - 36,478,548 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hspa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473436,476,372 - 36,478,548 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HSPA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381464,535,905 - 64,543,237 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1464,535,905 - 64,546,173 (+)EnsemblGRCh38hg38GRCh38
GRCh371465,002,623 - 65,009,955 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361464,076,939 - 64,079,708 (+)NCBINCBI36Build 36hg18NCBI36
Build 341464,072,375 - 64,079,705NCBI
Celera1445,064,915 - 45,067,684 (+)NCBICelera
Cytogenetic Map14q23.3NCBI
HuRef1445,179,854 - 45,182,623 (+)NCBIHuRef
CHM1_11464,946,881 - 64,949,650 (+)NCBICHM1_1
T2T-CHM13v2.01458,743,704 - 58,751,035 (+)NCBIT2T-CHM13v2.0
Hspa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391276,450,688 - 76,453,712 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1276,450,950 - 76,453,712 (+)EnsemblGRCm39 Ensembl
GRCm381276,403,812 - 76,406,938 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1276,404,176 - 76,406,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv371277,505,163 - 77,507,925 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361277,323,016 - 77,325,778 (+)NCBIMGSCv36mm8
Celera1277,495,202 - 77,497,964 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1233.73NCBI
Hspa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86100,864,172 - 100,866,946 (+)NCBIGRCr8
mRatBN7.2695,128,504 - 95,131,281 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl695,128,350 - 95,131,287 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx695,522,154 - 95,524,659 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0695,820,668 - 95,823,173 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0695,249,481 - 95,251,986 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0699,433,575 - 99,436,288 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl699,433,550 - 99,436,289 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06108,843,592 - 108,846,304 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4699,000,541 - 99,003,041 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1699,003,760 - 99,006,497 (+)NCBI
Celera693,553,144 - 93,555,644 (+)NCBICelera
Cytogenetic Map6q24NCBI
Hspa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554665,344,366 - 5,347,707 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554665,344,366 - 5,347,707 (-)NCBIChiLan1.0ChiLan1.0
HSPA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21565,654,654 - 65,657,531 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11464,871,169 - 64,874,046 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01445,124,326 - 45,127,105 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11463,373,462 - 63,376,240 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1463,373,840 - 63,375,762 (+)Ensemblpanpan1.1panPan2
HSPA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1838,967,104 - 38,969,806 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl838,967,400 - 38,969,313 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha838,658,560 - 38,661,200 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0839,188,332 - 39,191,053 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl839,188,237 - 39,191,347 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1838,810,203 - 38,812,923 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0838,881,460 - 38,884,183 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0839,241,859 - 39,244,579 (+)NCBIUU_Cfam_GSD_1.0
Hspa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864065,945,617 - 65,948,642 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364958,243,369 - 8,246,082 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1788,607,140 - 88,609,947 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2794,987,337 - 94,990,126 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSPA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12441,747,485 - 41,750,266 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2441,747,864 - 41,749,783 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605329,924,231 - 29,927,019 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004837410   ⟹   XP_004837467
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473436,476,372 - 36,478,548 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004837467 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000039418
  ENSHGLP00100012161
  ENSHGLP00100043139
GenBank Protein JAO01671 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004837467   ⟸   XM_004837410
- UniProtKB: A0A0P6JBK0 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011390 UniProtKB/TrEMBL
  ENSHGLG00100009010 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000016108 UniProtKB/TrEMBL
  ENSHGLT00100012303 UniProtKB/TrEMBL
  ENSHGLT00100046745 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.10 UniProtKB/TrEMBL
  3.30.30.30 UniProtKB/TrEMBL
  3.30.420.40 UniProtKB/TrEMBL
InterPro ATPase_NBD UniProtKB/TrEMBL
  Heat_shock_70_CS UniProtKB/TrEMBL
  HSP70_C_sf UniProtKB/TrEMBL
  HSP70_peptide-bd_sf UniProtKB/TrEMBL
  Hsp_70_fam UniProtKB/TrEMBL
NCBI Gene Hspa2 ENTREZGENE
PANTHER HEAT SHOCK-RELATED 70 KDA PROTEIN 2 UniProtKB/TrEMBL
  PTHR19375 UniProtKB/TrEMBL
Pfam HSP70 UniProtKB/TrEMBL
PRINTS HEATSHOCK70 UniProtKB/TrEMBL
PROSITE HSP70_1 UniProtKB/TrEMBL
  HSP70_2 UniProtKB/TrEMBL
  HSP70_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF100920 UniProtKB/TrEMBL
  SSF100934 UniProtKB/TrEMBL
  SSF53067 UniProtKB/TrEMBL
UniProt A0A0P6JBK0 ENTREZGENE, UniProtKB/TrEMBL