Exd2 (exonuclease 3'-5' domain containing 2) - Rat Genome Database

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Gene: Exd2 (exonuclease 3'-5' domain containing 2) Rattus norvegicus
Analyze
Symbol: Exd2
Name: exonuclease 3'-5' domain containing 2
RGD ID: 1311087
Description: Predicted to enable 3'-5' exonuclease activity; metal ion binding activity; and protein homodimerization activity. Predicted to be involved in DNA double-strand break processing; double-strand break repair via homologous recombination; and replication fork processing. Predicted to be located in intermediate filament cytoskeleton; mitochondrial outer membrane; and site of DNA damage. Predicted to be active in cytoplasm and nucleus. Orthologous to human EXD2 (exonuclease 3'-5' domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Exdl2; exonuclease 3''-5'' domain-like 2; exonuclease 3'-5' domain-containing protein 2; LOC362759; RGD1311087; similar to expressed sequence C85658
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86105,847,931 - 105,881,780 (+)NCBIGRCr8
mRatBN7.26100,116,867 - 100,150,452 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6100,116,867 - 100,150,442 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6100,282,295 - 100,316,178 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06100,581,990 - 100,615,873 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0699,957,060 - 99,990,674 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06104,017,620 - 104,051,442 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6104,017,607 - 104,051,446 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06112,192,441 - 112,226,159 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46104,231,115 - 104,265,354 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16104,234,693 - 104,268,073 (+)NCBI
Celera697,974,785 - 98,008,358 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 48 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exd2Rat(1->4)-beta-D-glucan multiple interactionsISORGD:15522726480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EXD2 mRNACTDPMID:36331819
Exd2Rat1,2-dimethylhydrazine decreases expressionISORGD:155227264804641,2-Dimethylhydrazine results in decreased expression of EXD2 mRNACTDPMID:22206623
Exd2Rat17beta-estradiol decreases expressionISORGD:15522726480464Estradiol results in decreased expression of EXD2 mRNACTDPMID:39298647
Exd2Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISORGD:155227264804642,3',4,4',5-pentachlorobiphenyl results in increased expression of EXD2 mRNACTDPMID:31388691
Exd2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of EXD2 mRNACTDPMID:21215274
Exd2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:15522726480464Tetrachlorodibenzodioxin affects the expression of EXD2 mRNACTDPMID:21570461
Exd2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of EXD2 mRNACTDPMID:32109520
Exd2Rat2-methylcholine affects expressionISORGD:13223576480464beta-methylcholine affects the expression of EXD2 mRNACTDPMID:21179406
Exd2Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of EXD2 proteinCTDPMID:34915118
Exd2Rat4,4'-sulfonyldiphenol decreases expressionISORGD:15522726480464bisphenol S results in decreased expression of EXD2 mRNACTDPMID:39298647
Exd2Ratacrolein multiple interactionsISORGD:13223576480464[Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased oxidation of EXD2 mRNACTDPMID:32845096
Exd2Ratbenzo[a]pyrene increases expressionISORGD:15522726480464Benzo(a)pyrene results in increased expression of EXD2 mRNACTDPMID:22228805
Exd2Ratbeta-lapachone increases expressionISORGD:13223576480464beta-lapachone results in increased expression of EXD2 mRNACTDPMID:38218311
Exd2Ratbis(2-ethylhexyl) phthalate increases expressionISORGD:15522726480464Diethylhexyl Phthalate results in increased expression of EXD2 mRNACTDPMID:34319233
Exd2Ratbisphenol A affects expressionISORGD:13223576480464bisphenol A affects the expression of EXD2 mRNACTDPMID:22574217
Exd2Ratbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of EXD2 geneCTDPMID:28505145
Exd2Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of EXD2 mRNACTDPMID:25181051
Exd2Ratbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with Testosterone] results in decreased expression of EXD2 mRNA; [bisphenol A co-treated more ...CTDPMID:26496021|PMID:31129395
Exd2Ratbisphenol A decreases expressionISORGD:15522726480464bisphenol A results in decreased expression of EXD2 mRNACTDPMID:26063408
Exd2Ratcadmium dichloride decreases expressionISORGD:13223576480464Cadmium Chloride results in decreased expression of EXD2 mRNACTDPMID:38568856

1 to 20 of 48 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exd2RatDNA double-strand break processing involved_inISORGD:13223571624291 PMID:26807646RGDPMID:26807646
Exd2Ratdouble-strand break repair involved_inISORGD:13223571624291 PMID:26807646RGDPMID:26807646
Exd2Ratdouble-strand break repair via homologous recombination involved_inISORGD:13223571624291 PMID:26807646RGDPMID:26807646
Exd2Ratnucleobase-containing compound metabolic process involved_inIEAInterPro:IPR0025621600115GO_REF:0000002InterProGO_REF:0000002
Exd2Ratreplication fork processing involved_inISORGD:13223571624291 PMID:31255466RGDPMID:31255466

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exd2Ratcytoplasm is_active_inIBAFB:FBgn0032924|FB:FBgn0037901|PANTHER:PTN000341338|TAIR:locus:2011826|TAIR:locus:2081526|TAIR:locus:2164255|UniProtKB:Q9NVH0|WB:WBGene000035041600115GO_REF:0000033GO_CentralGO_REF:0000033
Exd2Ratintermediate filament cytoskeleton located_inISORGD:1322357|UniProtKB:Q9NVH0-1|UniProtKB:Q9NVH0-21624291 RGDGO_REF:0000052
Exd2Ratmitochondrial outer membrane located_inISORGD:13223571624291 PMID:29599527, PMID:31127291RGDPMID:29599527|PMID:31127291
Exd2Ratmitochondrion located_inISORGD:1322357|UniProtKB:Q9NVH0-1|UniProtKB:Q9NVH0-21624291 RGDGO_REF:0000052
Exd2Ratnucleus is_active_inIBAPANTHER:PTN000341338|WB:WBGene000035041600115GO_REF:0000033GO_CentralGO_REF:0000033
Exd2Ratsite of DNA damage located_inISORGD:13223571624291 PMID:31255466RGDPMID:31255466

Molecular Function
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Exd2Rat3'-5' exonuclease activity enablesISORGD:13223571624291 PMID:26807646, PMID:31255466RGDPMID:26807646|PMID:31255466
Exd2Rat3'-5' exonuclease activity enablesIEAInterPro:IPR0025621600115GO_REF:0000002InterProGO_REF:0000002
Exd2Rat3'-5' exonuclease activity enablesIBAFB:FBgn0032924|FB:FBgn0037901|FB:FBgn0038608|PANTHER:PTN008550069|TAIR:locus:2081526|TAIR:locus:2119525|TAIR:locus:2164255|UniProtKB:Q9NVH01600115GO_REF:0000033GO_CentralGO_REF:0000033
Exd2Rat3'-5' exonuclease activity enablesIEAARBA:ARBA000287701600115GO_REF:0000117UniProtGO_REF:0000117
Exd2Rat3'-5'-DNA exonuclease activity enablesISORGD:13223571624291 PMID:31127291RGDPMID:31127291
Exd2Rat3'-5'-RNA exonuclease activity enablesISORGD:13223571624291 PMID:31127291RGDPMID:31127291
Exd2Ratexonuclease activity enablesIEAUniProtKB-KW:KW-02691600115GO_REF:0000043UniProtGO_REF:0000043
Exd2Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Exd2Ratmagnesium ion binding enablesISORGD:13223571624291 PMID:31127291RGDPMID:31127291
Exd2Ratmanganese ion binding enablesISORGD:13223571624291 PMID:31127291RGDPMID:31127291
Exd2Ratnuclease activity enablesIEAUniProtKB-KW:KW-05401600115GO_REF:0000043UniProtGO_REF:0000043
Exd2Ratnucleic acid binding enablesIEAInterPro:IPR002562|InterPro:IPR0363971600115GO_REF:0000002InterProGO_REF:0000002
Exd2Ratprotein binding enablesISORGD:13223571624291UniProtKB:P38398|UniProtKB:P49959|UniProtKB:Q99708 PMID:26807646RGDPMID:26807646
Exd2Ratprotein homodimerization activity enablesISORGD:13223571624291 PMID:31127291RGDPMID:31127291
Exd2Ratsingle-stranded DNA 3'-5' DNA exonuclease activity enablesISORGD:13223571624291 PMID:26807646RGDPMID:26807646
1 to 15 of 15 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:22871113   PMID:26807646   PMID:29599527   PMID:31127291   PMID:31255466  



Exd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86105,847,931 - 105,881,780 (+)NCBIGRCr8
mRatBN7.26100,116,867 - 100,150,452 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6100,116,867 - 100,150,442 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6100,282,295 - 100,316,178 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06100,581,990 - 100,615,873 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0699,957,060 - 99,990,674 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06104,017,620 - 104,051,442 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6104,017,607 - 104,051,446 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06112,192,441 - 112,226,159 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46104,231,115 - 104,265,354 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16104,234,693 - 104,268,073 (+)NCBI
Celera697,974,785 - 98,008,358 (+)NCBICelera
Cytogenetic Map6q24NCBI
EXD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381469,191,498 - 69,244,018 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1469,191,498 - 69,244,020 (+)EnsemblGRCh38hg38GRCh38
GRCh371469,658,215 - 69,710,735 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361468,746,231 - 68,778,825 (+)NCBINCBI36Build 36hg18NCBI36
Build 341468,746,230 - 68,778,825NCBI
Celera1449,722,349 - 49,774,877 (+)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1449,828,887 - 49,881,419 (+)NCBIHuRef
CHM1_11469,596,430 - 69,648,894 (+)NCBICHM1_1
T2T-CHM13v2.01463,404,602 - 63,457,085 (+)NCBIT2T-CHM13v2.0
Exd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391280,509,869 - 80,544,909 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1280,509,869 - 80,547,001 (+)EnsemblGRCm39 Ensembl
GRCm381280,463,095 - 80,498,135 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1280,463,095 - 80,500,227 (+)EnsemblGRCm38mm10GRCm38
MGSCv371281,564,082 - 81,599,122 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361281,394,842 - 81,416,970 (+)NCBIMGSCv36mm8
Celera1281,928,182 - 81,963,154 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1236.73NCBI
Exd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554661,110,395 - 1,169,242 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554661,114,299 - 1,169,124 (-)NCBIChiLan1.0ChiLan1.0
EXD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21570,313,041 - 70,366,036 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11469,527,465 - 69,582,549 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01449,783,072 - 49,835,645 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11468,656,455 - 68,708,773 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1468,656,669 - 68,707,834 (+)Ensemblpanpan1.1panPan2
EXD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1843,028,537 - 43,082,038 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl843,042,563 - 43,187,969 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha842,717,745 - 42,773,001 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0843,257,837 - 43,313,332 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl843,257,911 - 43,316,242 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1842,872,325 - 42,927,784 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0842,946,902 - 43,002,520 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0843,306,406 - 43,361,842 (+)NCBIUU_Cfam_GSD_1.0
Exd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864061,711,892 - 61,758,994 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649512,432,731 - 12,479,876 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649512,432,752 - 12,479,807 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl792,848,032 - 92,913,771 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1792,847,958 - 92,909,044 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2799,038,091 - 99,131,917 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EXD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12446,431,309 - 46,480,500 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2446,444,282 - 46,482,845 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605334,655,161 - 34,706,362 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473431,819,440 - 31,866,937 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473431,822,927 - 31,866,678 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Exd2
324 total Variants

Predicted Target Of
Summary Value
Count of predictions:495
Count of miRNA genes:243
Interacting mature miRNAs:290
Transcripts:ENSRNOT00000033378
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 33 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat

1 to 10 of 33 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000033378   ⟹   ENSRNOP00000030862
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6100,116,978 - 100,150,442 (+)Ensembl
Rnor_6.0 Ensembl6104,017,607 - 104,051,446 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094099   ⟹   ENSRNOP00000079247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6100,116,867 - 100,146,009 (+)Ensembl
RefSeq Acc Id: NM_001108715   ⟹   NP_001102185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86105,848,202 - 105,881,777 (+)NCBI
mRatBN7.26100,116,867 - 100,150,444 (+)NCBI
Rnor_6.06104,017,889 - 104,051,434 (+)NCBI
Rnor_5.06112,192,441 - 112,226,159 (+)NCBI
RGSC_v3.46104,231,115 - 104,265,354 (+)RGD
Celera697,974,785 - 98,008,358 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240286   ⟹   XP_006240348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86105,847,931 - 105,881,780 (+)NCBI
mRatBN7.26100,116,901 - 100,150,452 (+)NCBI
Rnor_6.06104,017,620 - 104,051,442 (+)NCBI
Rnor_5.06112,192,441 - 112,226,159 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039112511   ⟹   XP_038968439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86105,847,931 - 105,881,780 (+)NCBI
mRatBN7.26100,116,901 - 100,150,452 (+)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001102185 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420937 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420938 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240348 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968439 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66432 (Get FASTA)   NCBI Sequence Viewer  
  EDL81378 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030862
  ENSRNOP00000030862.5
  ENSRNOP00000079247.1
1 to 10 of 10 rows
RefSeq Acc Id: NP_001102185   ⟸   NM_001108715
- Sequence:
RefSeq Acc Id: XP_006240348   ⟸   XM_006240286
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000030862   ⟸   ENSRNOT00000033378
RefSeq Acc Id: XP_038968439   ⟸   XM_039112511
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000079247   ⟸   ENSRNOT00000094099
3'-5' exonuclease

Name Modeler Protein Id AA Range Protein Structure
AF-B2GUW4-F1-model_v2 AlphaFold B2GUW4 1-648 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 24 of 24 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-36912 BioCyc
Ensembl Genes ENSRNOG00000027707 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033378 ENTREZGENE
  ENSRNOT00000033378.6 UniProtKB/TrEMBL
  ENSRNOT00000094099.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7135396 IMAGE-MGC_LOAD
InterPro 3-5_Exonuclease_domain UniProtKB/TrEMBL
  3_5_exonuclease UniProtKB/TrEMBL
  PolynucTfrase_RNaseH_fold UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
KEGG Report rno:362759 UniProtKB/TrEMBL
MGC_CLONE MGC:187466 IMAGE-MGC_LOAD
NCBI Gene 362759 ENTREZGENE
PANTHER 3-5 EXONUCLEASE UniProtKB/TrEMBL
  EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam 3_5_exonuc UniProtKB/TrEMBL
PhenoGen Exd2 PhenoGen
RatGTEx ENSRNOG00000027707 RatGTEx
SMART 35EXOc UniProtKB/TrEMBL
Superfamily-SCOP RNaseH_fold UniProtKB/TrEMBL
UniProt A0A8I5ZQG7_RAT UniProtKB/TrEMBL
  B2GUW4 ENTREZGENE, UniProtKB/TrEMBL
  F7FEI8 ENTREZGENE, UniProtKB/TrEMBL
1 to 24 of 24 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-03-24 Exd2  exonuclease 3'-5' domain containing 2  Exdl2  exonuclease 3''-5'' domain-like 2   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Exdl2  exonuclease 3''-5'' domain-like 2   Exdl2_predicted  exonuclease 3''-5'' domain-like 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Exdl2_predicted  exonuclease 3''-5'' domain-like 2 (predicted)  RGD1311087_predicted  similar to expressed sequence C85658 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1311087_predicted  similar to expressed sequence C85658 (predicted)  LOC362759_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362759_predicted  similar to expressed sequence C85658 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL