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Gene: Gpx2 (glutathione peroxidase 2) Rattus norvegicus
Symbol: Gpx2
Name: glutathione peroxidase 2
Description: Exhibits glutathione peroxidase activity. Predicted to be involved in several processes, including negative regulation of inflammatory response to antigenic stimulus; response to symbiotic bacterium; and temperature homeostasis. Predicted to localize to cytoplasm. Orthologous to human GPX2 (glutathione peroxidase 2); PARTICIPATES IN arachidonic acid metabolic pathway; glutathione metabolic pathway; INTERACTS WITH (+)-schisandrin B; (R)-lipoic acid; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glutathione peroxidase-gastrointestinal; GPx-2; GPX-GI; GSHPx-2; GSHPx-GI
Homo sapiens (human) : GPX2 (glutathione peroxidase 2)  HGNC  Alliance
Mus musculus (house mouse) : Gpx2 (glutathione peroxidase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpx2 (glutathione peroxidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GPX2 (glutathione peroxidase 2)
Canis lupus familiaris (dog) : GPX2 (glutathione peroxidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpx2 (glutathione peroxidase 2)
Sus scrofa (pig) : GPX2 (glutathione peroxidase 2)
Chlorocebus sabaeus (African green monkey) : GPX2 (glutathione peroxidase 2)
Heterocephalus glaber (naked mole-rat) : Gpx2 (glutathione peroxidase 2)
more info ...
Related Pseudogenes: Gpx2-ps1   Gpx2-ps2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0699,839,960 - 99,843,245 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl699,839,960 - 99,843,245 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06109,236,420 - 109,239,718 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4699,372,418 - 99,376,230 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1699,375,879 - 99,379,686 (-)NCBI
Celera693,912,759 - 93,916,226 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Gpx2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 727780
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.