Tshr Rat (S)-nicotine increases expression ISO TSHR (Homo sapiens) 6480464 Nicotine results in increased expression of TSHR mRNA CTD PMID:18247414 Tshr Rat 17beta-estradiol multiple interactions ISO TSHR (Homo sapiens) 6480464 Estradiol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP] CTD PMID:19766106 Tshr Rat 17beta-estradiol decreases expression ISO Tshr (Mus musculus) 6480464 Estradiol results in decreased expression of TSHR mRNA CTD PMID:19484750 Tshr Rat 2,2',4,4',5,5'-hexachlorobiphenyl decreases expression EXP 6480464 2 more ... CTD PMID:22889935 Tshr Rat 2,2',4,4',5,5'-hexachlorobiphenyl decreases expression ISO TSHR (Homo sapiens) 6480464 2 more ... CTD PMID:22889935 Tshr Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of TSHR mRNA CTD PMID:18178546 Tshr Rat 2-naphthylamine increases expression ISO TSHR (Homo sapiens) 6480464 2-Naphthylamine results in increased expression of TSHR mRNA CTD PMID:18247414 Tshr Rat 3',5'-cyclic AMP multiple interactions ISO TSHR (Homo sapiens) 6480464 [TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP more ... CTD PMID:19766106 and PMID:21123444 Tshr Rat 3',5'-cyclic AMP increases abundance ISO TSHR (Homo sapiens) 6480464 TSHR protein results in increased abundance of Cyclic AMP CTD PMID:21123444 Tshr Rat 3,3',5,5'-tetrabromobisphenol A decreases expression ISO Tshr (Mus musculus) 6480464 tetrabromobisphenol A results in decreased expression of TSHR protein CTD PMID:37487893 Tshr Rat 3,3',5-triiodo-L-thyronine decreases expression ISO Tshr (Mus musculus) 6480464 Triiodothyronine results in decreased expression of TSHR protein CTD PMID:37487893 Tshr Rat 4,4'-sulfonyldiphenol increases expression ISO TSHR (Homo sapiens) 6480464 bisphenol S results in increased expression of TSHR mRNA CTD PMID:27685785 Tshr Rat 4,4'-sulfonyldiphenol decreases expression ISO Tshr (Mus musculus) 6480464 bisphenol S results in decreased expression of TSHR protein CTD PMID:37487893 Tshr Rat 4-hydroxyphenyl retinamide decreases expression ISO Tshr (Mus musculus) 6480464 Fenretinide results in decreased expression of TSHR mRNA CTD PMID:28973697 Tshr Rat 5-azacytidine increases expression ISO TSHR (Homo sapiens) 6480464 Azacitidine results in increased expression of TSHR mRNA CTD PMID:17679169 Tshr Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of TSHR mRNA CTD PMID:22342233 Tshr Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of TSHR mRNA CTD PMID:36843608 Tshr Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of TSHR mRNA CTD PMID:31881176 Tshr Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of TSHR mRNA CTD PMID:28959563 Tshr Rat aflatoxin B1 decreases methylation ISO TSHR (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of TSHR gene CTD PMID:27153756 Tshr Rat aflatoxin B1 increases methylation ISO TSHR (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of TSHR intron CTD PMID:30157460 Tshr Rat Aflatoxin B2 alpha increases methylation ISO TSHR (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of TSHR intron CTD PMID:30157460 Tshr Rat aldehydo-D-glucose multiple interactions ISO Tshr (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of TSHR mRNA CTD PMID:37567420 Tshr Rat all-trans-retinoic acid decreases expression ISO TSHR (Homo sapiens) 6480464 Tretinoin results in decreased expression of TSHR mRNA CTD PMID:17679169 Tshr Rat all-trans-retinoic acid affects expression ISO TSHR (Homo sapiens) 6480464 Tretinoin affects the expression of TSHR mRNA CTD PMID:31600526 Tshr Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of TSHR mRNA CTD PMID:35163327 Tshr Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TSHR mRNA CTD PMID:16483693 Tshr Rat amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of TSHR mRNA CTD PMID:30779732 Tshr Rat Aroclor 1254 multiple interactions ISO TSHR (Homo sapiens) 6480464 Chlorodiphenyl (54% Chlorine) binds to and results in decreased activity of TSHR protein CTD PMID:17062616 Tshr Rat Aroclor 1254 decreases activity ISO TSHR (Homo sapiens) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased activity of TSHR protein CTD PMID:14759065 Tshr Rat Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of TSHR mRNA CTD PMID:18178546 Tshr Rat atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of TSHR mRNA CTD PMID:36841081 Tshr Rat benzo[a]pyrene increases expression ISO TSHR (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of TSHR mRNA CTD PMID:18247414 Tshr Rat benzo[a]pyrene decreases methylation ISO TSHR (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of TSHR 3' UTR CTD PMID:27901495 Tshr Rat benzo[a]pyrene affects methylation ISO TSHR (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of TSHR 5' UTR more ... CTD PMID:27901495 and PMID:30157460 Tshr Rat benzo[a]pyrene increases methylation ISO TSHR (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of TSHR promoter CTD PMID:27901495 Tshr Rat bis(2-ethylhexyl) phthalate affects expression EXP 6480464 Diethylhexyl Phthalate affects the expression of TSHR mRNA and Diethylhexyl Phthalate affects the expression of TSHR protein CTD PMID:35228410 Tshr Rat bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of TSHR mRNA and Diethylhexyl Phthalate results in decreased expression of TSHR protein CTD PMID:36714560 Tshr Rat bis(2-ethylhexyl) phthalate multiple interactions ISO TSHR (Homo sapiens) 6480464 TSHR protein affects the reaction [Diethylhexyl Phthalate results in increased expression of CCNE1 protein] more ... CTD PMID:30543897 Tshr Rat bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of TSHR protein CTD PMID:30543897 Tshr Rat bis(2-ethylhexyl) phthalate decreases expression ISO TSHR (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of TSHR mRNA CTD PMID:31163220 Tshr Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of TSHR mRNA CTD PMID:25181051 Tshr Rat bisphenol A decreases expression ISO Tshr (Mus musculus) 6480464 bisphenol A results in decreased expression of TSHR protein CTD PMID:37487893 Tshr Rat bisphenol A increases expression ISO Tshr (Mus musculus) 6480464 bisphenol A results in increased expression of TSHR mRNA CTD PMID:32156529 Tshr Rat bisphenol A affects expression ISO Tshr (Mus musculus) 6480464 bisphenol A affects the expression of TSHR mRNA CTD PMID:35341816 Tshr Rat bisphenol A increases methylation ISO TSHR (Homo sapiens) 6480464 bisphenol A results in increased methylation of TSHR gene CTD PMID:31601247 Tshr Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of TSHR mRNA CTD PMID:23238275 and PMID:30816183 Tshr Rat bisphenol A multiple interactions ISO TSHR (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of TSHR gene and bisphenol A inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP] CTD PMID:19766106 and PMID:31601247 Tshr Rat bleomycin A2 decreases expression EXP 6480464 Bleomycin results in decreased expression of TSHR mRNA CTD PMID:15808516 Tshr Rat bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of TSHR mRNA CTD PMID:12628495 Tshr Rat bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of TSHR mRNA CTD PMID:15976192 Tshr Rat cobalt atom multiple interactions ISO TSHR (Homo sapiens) 6480464 [Cobalt binds to dipyrido(3 more ... CTD PMID:21072367 Tshr Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of TSHR mRNA CTD PMID:26577399 Tshr Rat D-glucose multiple interactions ISO Tshr (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of TSHR mRNA CTD PMID:37567420 Tshr Rat DDT decreases localization ISO TSHR (Homo sapiens) 6480464 DDT results in decreased localization of TSHR protein CTD PMID:19214582 Tshr Rat DDT decreases activity ISO TSHR (Homo sapiens) 6480464 DDT results in decreased activity of TSHR protein CTD PMID:14759065 Tshr Rat DDT multiple interactions ISO TSHR (Homo sapiens) 6480464 DDT binds to and results in decreased activity of TSHR protein CTD PMID:17062616 Tshr Rat decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of TSHR mRNA CTD PMID:30844666 Tshr Rat diallyl trisulfide increases expression ISO TSHR (Homo sapiens) 6480464 diallyl trisulfide results in increased expression of TSHR protein CTD PMID:33751676 Tshr Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of TSHR mRNA CTD PMID:21266533 Tshr Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of TSHR mRNA CTD PMID:15620428 Tshr Rat diethylstilbestrol multiple interactions ISO TSHR (Homo sapiens) 6480464 Diethylstilbestrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP] CTD PMID:19766106 Tshr Rat diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of TSHR mRNA CTD PMID:37077353 Tshr Rat dimethylarsinic acid decreases expression EXP 6480464 Cacodylic Acid results in decreased expression of TSHR mRNA CTD PMID:16122865 Tshr Rat diuron increases expression EXP 6480464 Diuron results in increased expression of TSHR mRNA CTD PMID:21551480 and PMID:25152437 Tshr Rat dorsomorphin multiple interactions ISO TSHR (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TSHR mRNA CTD PMID:27188386 Tshr Rat efavirenz increases expression ISO TSHR (Homo sapiens) 6480464 efavirenz results in increased expression of TSHR mRNA CTD PMID:16030158 Tshr Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of TSHR mRNA CTD PMID:29391264 Tshr Rat folic acid affects expression ISO TSHR (Homo sapiens) 6480464 Folic Acid affects the expression of TSHR mRNA CTD PMID:34742744 Tshr Rat fructose multiple interactions ISO Tshr (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of TSHR mRNA CTD PMID:37567420 Tshr Rat fulvestrant multiple interactions ISO TSHR (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of TSHR gene CTD PMID:31601247 Tshr Rat furan increases expression EXP 6480464 furan results in increased expression of TSHR mRNA CTD PMID:25539665 Tshr Rat genistein decreases expression ISO Tshr (Mus musculus) 6480464 Genistein results in decreased expression of TSHR mRNA CTD PMID:32186404 Tshr Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of TSHR mRNA CTD PMID:33387578 Tshr Rat glucose multiple interactions ISO Tshr (Mus musculus) 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of TSHR mRNA CTD PMID:37567420 Tshr Rat glycidol decreases expression EXP 6480464 glycidol results in decreased expression of TSHR mRNA CTD PMID:24395379 Tshr Rat glyphosate multiple interactions ISO Tshr (Mus musculus) 6480464 Melatonin inhibits the reaction [Glyphosate results in decreased expression of TSHR mRNA] CTD PMID:33159990 Tshr Rat glyphosate increases expression EXP 6480464 Glyphosate results in increased expression of TSHR mRNA CTD PMID:36462676 Tshr Rat glyphosate decreases expression ISO Tshr (Mus musculus) 6480464 Glyphosate results in decreased expression of TSHR mRNA CTD PMID:33159990 Tshr Rat graphite affects expression EXP 6480464 Graphite affects the expression of TSHR mRNA CTD PMID:29933104 Tshr Rat ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of TSHR mRNA CTD PMID:37077353 Tshr Rat lead(0) decreases expression EXP 6480464 Lead results in decreased expression of TSHR protein CTD PMID:33223335 Tshr Rat malathion decreases expression EXP 6480464 Malathion results in decreased expression of TSHR protein CTD PMID:29143548 Tshr Rat melatonin multiple interactions ISO Tshr (Mus musculus) 6480464 Melatonin inhibits the reaction [Glyphosate results in decreased expression of TSHR mRNA] CTD PMID:33159990 Tshr Rat methimazole increases expression EXP 6480464 Methimazole results in increased expression of TSHR mRNA CTD PMID:22342233 Tshr Rat methimazole decreases expression ISO TSHR (Homo sapiens) 6480464 Methimazole results in decreased expression of TSHR mRNA CTD PMID:22342233 Tshr Rat methimazole increases expression ISO TSHR (Homo sapiens) 6480464 Methimazole results in increased expression of TSHR mRNA CTD PMID:22342233 Tshr Rat N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TSHR mRNA CTD PMID:28801915 Tshr Rat N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of TSHR mRNA CTD PMID:15976192 Tshr Rat nevirapine increases expression ISO TSHR (Homo sapiens) 6480464 Nevirapine results in increased expression of TSHR mRNA CTD PMID:16030158 Tshr Rat nickel atom decreases expression ISO TSHR (Homo sapiens) 6480464 Nickel results in decreased expression of TSHR mRNA CTD PMID:24768652 and PMID:25583101 Tshr Rat nicotine increases expression ISO TSHR (Homo sapiens) 6480464 Nicotine results in increased expression of TSHR mRNA CTD PMID:18247414 Tshr Rat Nonylphenol decreases expression EXP 6480464 nonylphenol results in decreased expression of TSHR mRNA CTD PMID:15620428 Tshr Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of TSHR mRNA CTD PMID:15976192 Tshr Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of TSHR mRNA CTD PMID:33387578 Tshr Rat paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of TSHR mRNA CTD PMID:32680482 Tshr Rat perchlorate decreases expression EXP 6480464 perchlorate results in decreased expression of TSHR mRNA CTD PMID:35385113 Tshr Rat perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of TSHR mRNA CTD PMID:35163327 Tshr Rat perfluorooctanoic acid decreases expression ISO TSHR (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of TSHR mRNA CTD PMID:36326898 Tshr Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of TSHR mRNA CTD PMID:35163327 Tshr Rat picrotoxin increases expression EXP 6480464 Picrotoxin results in increased expression of TSHR mRNA CTD PMID:15170462 Tshr Rat quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of TSHR mRNA and Quercetin results in decreased expression of TSHR protein CTD PMID:24447974 Tshr Rat resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of TSHR mRNA and resveratrol results in decreased expression of TSHR protein CTD PMID:28668442 Tshr Rat resveratrol multiple interactions ISO TSHR (Homo sapiens) 6480464 resveratrol inhibits the reaction [[TSHB protein results in increased activity of TSHR protein] which results in increased abundance of Cyclic AMP] CTD PMID:19766106 Tshr Rat SB 431542 multiple interactions ISO TSHR (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TSHR mRNA CTD PMID:27188386 Tshr Rat sodium perchlorate increases expression EXP 6480464 sodium perchlorate results in increased expression of TSHR mRNA and sodium perchlorate results in increased expression of TSHR protein CTD PMID:29139221 Tshr Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of TSHR mRNA CTD PMID:15976192 Tshr Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of TSHR mRNA CTD PMID:15976192 Tshr Rat thyroxine decreases activity ISO Tshr (Mus musculus) 6480464 Thyroxine results in decreased activity of TSHR protein CTD PMID:17332529 Tshr Rat trans-piceid multiple interactions ISO Tshr (Mus musculus) 6480464 polydatin inhibits the reaction [TSHR protein results in decreased expression of NFE2L2 protein] more ... CTD PMID:31705858 Tshr Rat triadimefon increases expression EXP 6480464 triadimefon results in increased expression of TSHR mRNA CTD PMID:16643972 Tshr Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of TSHR mRNA CTD PMID:33387578 Tshr Rat trichostatin A increases expression ISO TSHR (Homo sapiens) 6480464 trichostatin A results in increased expression of TSHR mRNA CTD PMID:17679169 Tshr Rat triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of TSHR mRNA CTD PMID:25646720 Tshr Rat triptonide increases expression ISO Tshr (Mus musculus) 6480464 triptonide results in increased expression of TSHR mRNA CTD PMID:33045310 Tshr Rat valproic acid decreases methylation ISO TSHR (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of TSHR gene CTD PMID:29154799 Tshr Rat valproic acid affects expression ISO Tshr (Mus musculus) 6480464 Valproic Acid affects the expression of TSHR mRNA CTD PMID:17292431 Tshr Rat vemurafenib multiple interactions ISO TSHR (Homo sapiens) 6480464 [BRAF protein mutant form affects the susceptibility to vemurafenib] which affects the expression of TSHR mRNA more ... CTD PMID:26751190 Tshr Rat venlafaxine hydrochloride increases expression EXP 6480464 Venlafaxine Hydrochloride results in increased expression of TSHR mRNA CTD PMID:25423262 Tshr Rat vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of TSHR gene CTD PMID:31079544 Tshr Rat vorinostat multiple interactions ISO TSHR (Homo sapiens) 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:25705225 more ... Tshr Rat vorinostat increases expression ISO TSHR (Homo sapiens) 6480464 Vorinostat results in increased expression of TSHR mRNA CTD PMID:25705225 more ...