 Gene Ontology Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Component
Molecular Function
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Analyze GeneStrainQTL List |
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Gene Annotator (Annotation Comparison) |
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Cellular Component
Molecular Function
Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | GOA data from the GO Consortium |
| 3. | Kim SO, etal., J Cell Biochem. 1998 Jun 15;69(4):506-21. |
| 4. | MGD data from the GO Consortium |
| 5. | RGD automated data pipeline |
| 6. | RGD automated import pipeline for gene-chemical interactions |
| 7. | RGD comprehensive gene curation |
References - uncuratedGenomics
Comparative Map Data| Cdkl1 (Rattus norvegicus - Norway rat) |
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| CDKL1 (Homo sapiens - human) |
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| Cdkl1 (Mus musculus - house mouse) |
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| Cdkl1 (Chinchilla lanigera - long-tailed chinchilla) |
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| CDKL1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| CDKL1 (Canis lupus familiaris - dog) |
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| Cdkl1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| CDKL1 (Sus scrofa - pig) |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 1 | 11 | 8 | 4 | 2 | 16 | 21 | 8 | 29 | |||||||
| Low | 21 | 37 | 12 | 7 | 2 | 1 | 8 | 10 | 4 | 11 | 3 | 37 | 6 | 8 | 8 | |
| Below cutoff | 6 | 1 | 4 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001025121 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006240171 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006240172 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006240173 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07064731 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01044909 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01044910 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01044911 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01044912 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01044913 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC081896 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473947 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | NM_001025121 ⟹ NP_001020292 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
GCATTTAGTTGATGAGGCTCGAGAGCGATCGGTTCTCGTATTTCATAAGCGACCTTTAAAAACThide sequence |
| RefSeq Acc Id: | XM_006240171 ⟹ XP_006240233 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
AACTTCTAAAACTCTTAGAATCCTGAAGCAAGAACACATCTATAGGGCAGGTACGAGTCAAATThide sequence |
| RefSeq Acc Id: | XM_006240172 ⟹ XP_006240234 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
GCTGGAGCACTCTGCCAGGACAGCCTGGGTGCAGGCGCTATCCCGCAGACGCTCCACGCTGTGAhide sequence |
| RefSeq Acc Id: | XM_006240173 ⟹ XP_006240235 | ||||||||||||||
| RefSeq Status: | |||||||||||||||
| Type: | CODING | ||||||||||||||
| Position: |
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| Sequence: |
AGCTCGGATAGAATTCCCAAAGGGGTCGGGGGCAGCACATTCTTGTTTCTGAGTCCATCTGCCChide sequence |
Protein Sequences| Protein RefSeqs | NP_001020292 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006240233 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006240234 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006240235 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAH81896 | (Get FASTA) | NCBI Sequence Viewer |
| EDM03530 | (Get FASTA) | NCBI Sequence Viewer | |
| Q66HE7 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001020292 ⟸ NM_001025121 |
| - UniProtKB: | Q66HE7 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVhide sequence |
| RefSeq Acc Id: | XP_006240233 ⟸ XM_006240171 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HE7 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVhide sequence |
| RefSeq Acc Id: | XP_006240234 ⟸ XM_006240172 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HE7 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVhide sequence |
| RefSeq Acc Id: | XP_006240235 ⟸ XM_006240173 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MSELEDLLASAQASRPLFPSLSQQAQGLSCLPSRPPSSEPSFCSNLLFLPQAAASKPLIPSPSRhide sequence |
TranscriptomePromoters| RGD ID: | 13694640 | |||||||||
| Promoter ID: | EPDNEW_R5163 | |||||||||
| Type: | single initiation site | |||||||||
| Name: | Cdkl1_1 | |||||||||
| Description: | cyclin dependent kinase like 1 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1305080 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000038720 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000006374 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000006374 | ENTREZGENE, UniProtKB/Swiss-Prot |
| IMAGE_CLONE | IMAGE:7110321 | IMAGE-MGC_LOAD |
| InterPro | Kinase-like_dom_sf | UniProtKB/Swiss-Prot |
| Prot_kinase_dom | UniProtKB/Swiss-Prot | |
| Protein_kinase_ATP_BS | UniProtKB/Swiss-Prot | |
| Ser/Thr_kinase_AS | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:314198 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:93810 | IMAGE-MGC_LOAD |
| NCBI Gene | 314198 | ENTREZGENE |
| Pfam | Pkinase | UniProtKB/Swiss-Prot |
| PharmGKB | CDKL1 | RGD |
| PhenoGen | Cdkl1 | PhenoGen |
| PROSITE | PROTEIN_KINASE_ATP | UniProtKB/Swiss-Prot |
| PROTEIN_KINASE_DOM | UniProtKB/Swiss-Prot | |
| PROTEIN_KINASE_ST | UniProtKB/Swiss-Prot | |
| SMART | S_TKc | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | SSF56112 | UniProtKB/Swiss-Prot |
| UniGene | Rn.182073 | ENTREZGENE |
| UniProt | CDKL1_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2016-01-13 | Cdkl1 | cyclin dependent kinase like 1 | Cdkl1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-04-30 | Cdkl1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) | Cdkl1_predicted | cyclin-dependent kinase-like 1 (CDC2-related kinase) (predicted) | 'predicted' is removed | 2292626 | APPROVED |
| 2005-01-12 | Cdkl1_predicted | cyclin-dependent kinase-like 1 (CDC2-related kinase) (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |
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| More on Cdkl1 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1305080 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-11-27 |
| Status: | ACTIVE |
