CDKL1 (cyclin dependent kinase like 1) - Rat Genome Database

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Gene: CDKL1 (cyclin dependent kinase like 1) Sus scrofa
Analyze
Symbol: CDKL1
Name: cyclin dependent kinase like 1
RGD ID: 13938125
Description: ENCODES a protein that exhibits ATP binding (inferred); protein kinase activity (inferred); protein serine/threonine kinase activity (inferred); INVOLVED IN heart development (ortholog); ASSOCIATED WITH Noonan syndrome 9 (ortholog); FOUND IN intracellular membrane-bounded organelle (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclin-dependent kinase-like 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1180,078,659 - 180,145,054 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11180,081,385 - 180,145,851 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21200,424,327 - 200,440,560 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CDKL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1180,078,659 - 180,145,054 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11180,081,385 - 180,145,851 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21200,424,327 - 200,440,560 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDKL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381450,326,265 - 50,397,298 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1450,326,265 - 50,416,461 (-)EnsemblGRCh38hg38GRCh38
GRCh371450,792,983 - 50,864,016 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361449,866,470 - 49,932,367 (-)NCBINCBI36Build 36hg18NCBI36
Build 341449,866,469 - 49,932,367NCBI
Celera1430,663,847 - 30,729,727 (-)NCBICelera
Cytogenetic Map14q21.3NCBI
HuRef1430,921,968 - 30,987,930 (-)NCBIHuRef
CHM1_11450,735,355 - 50,801,213 (-)NCBICHM1_1
T2T-CHM13v2.01444,532,486 - 44,603,508 (-)NCBIT2T-CHM13v2.0
Cdkl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391269,791,944 - 69,838,057 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1269,793,622 - 69,838,041 (-)EnsemblGRCm39 Ensembl
GRCm381269,745,167 - 69,791,196 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1269,746,848 - 69,791,267 (-)EnsemblGRCm38mm10GRCm38
MGSCv371270,847,835 - 70,891,694 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361270,665,453 - 70,709,312 (-)NCBIMGSCv36mm8
Celera1270,842,757 - 70,886,848 (-)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1228.94NCBI
Cdkl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8693,960,157 - 94,005,207 (-)NCBIGRCr8
mRatBN7.2688,224,154 - 88,273,434 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,224,143 - 88,270,276 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx688,623,989 - 88,667,896 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0688,923,441 - 88,967,352 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0688,363,180 - 88,407,097 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,076,247 - 92,123,108 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,077,416 - 92,121,351 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06101,525,767 - 101,572,007 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4691,800,976 - 91,869,815 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.163,426,823 - 3,447,743 (-)NCBI
Celera686,720,262 - 86,764,060 (-)NCBICelera
Cytogenetic Map6q24NCBI
Cdkl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540912,419,556 - 12,472,215 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540912,419,556 - 12,472,215 (+)NCBIChiLan1.0ChiLan1.0
CDKL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21551,467,099 - 51,535,020 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11450,683,602 - 50,752,380 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01430,917,602 - 30,987,992 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11449,213,925 - 49,291,192 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1449,223,146 - 49,291,192 (-)Ensemblpanpan1.1panPan2
CDKL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1826,771,498 - 26,828,287 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl826,773,636 - 26,828,270 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha826,525,498 - 26,581,908 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0826,949,620 - 27,006,081 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl826,949,620 - 27,006,517 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1826,604,557 - 26,661,001 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0826,676,990 - 26,733,441 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0826,995,836 - 27,052,284 (-)NCBIUU_Cfam_GSD_1.0
Cdkl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864058,966,730 - 59,018,050 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649515,173,643 - 15,228,490 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649515,173,672 - 15,225,044 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDKL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12427,401,003 - 27,468,961 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2427,396,911 - 27,469,284 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605315,723,170 - 15,789,575 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdkl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473118,490,755 - 18,543,211 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473118,490,780 - 18,543,364 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CDKL1
802 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 5 14 12 23 3 6 1

Sequence


Ensembl Acc Id: ENSSSCT00000061065   ⟹   ENSSSCP00000036467
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1180,078,659 - 180,145,032 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000075014   ⟹   ENSSSCP00000071907
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1180,084,102 - 180,145,054 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000078310   ⟹   ENSSSCP00000069969
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1180,086,618 - 180,145,054 (-)Ensembl
RefSeq Acc Id: XM_021101457   ⟹   XP_020957116
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11180,081,385 - 180,144,986 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021101459   ⟹   XP_020957118
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11180,081,385 - 180,145,742 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021101467   ⟹   XP_020957126
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11180,081,385 - 180,145,196 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021101470   ⟹   XP_020957129
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11180,081,385 - 180,145,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021101475   ⟹   XP_020957134
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11180,081,385 - 180,145,851 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021101479   ⟹   XP_020957138
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11180,081,385 - 180,145,742 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021101482   ⟹   XP_020957141
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11180,081,385 - 180,144,599 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020957134   ⟸   XM_021101475
- Peptide Label: isoform X1
- UniProtKB: A0A286ZXQ3 (UniProtKB/TrEMBL),   A0A8D0J2K9 (UniProtKB/TrEMBL),   A0A4X1SGI2 (UniProtKB/TrEMBL),   A0A8D1QAA2 (UniProtKB/TrEMBL),   A0A8D0J518 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020957138   ⟸   XM_021101479
- Peptide Label: isoform X1
- UniProtKB: A0A286ZXQ3 (UniProtKB/TrEMBL),   A0A8D0J2K9 (UniProtKB/TrEMBL),   A0A4X1SGI2 (UniProtKB/TrEMBL),   A0A8D1QAA2 (UniProtKB/TrEMBL),   A0A8D0J518 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020957118   ⟸   XM_021101459
- Peptide Label: isoform X1
- UniProtKB: A0A286ZXQ3 (UniProtKB/TrEMBL),   A0A8D0J2K9 (UniProtKB/TrEMBL),   A0A4X1SGI2 (UniProtKB/TrEMBL),   A0A8D1QAA2 (UniProtKB/TrEMBL),   A0A8D0J518 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020957126   ⟸   XM_021101467
- Peptide Label: isoform X1
- UniProtKB: A0A286ZXQ3 (UniProtKB/TrEMBL),   A0A8D0J2K9 (UniProtKB/TrEMBL),   A0A4X1SGI2 (UniProtKB/TrEMBL),   A0A8D1QAA2 (UniProtKB/TrEMBL),   A0A8D0J518 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020957129   ⟸   XM_021101470
- Peptide Label: isoform X1
- UniProtKB: A0A286ZXQ3 (UniProtKB/TrEMBL),   A0A8D0J2K9 (UniProtKB/TrEMBL),   A0A4X1SGI2 (UniProtKB/TrEMBL),   A0A8D1QAA2 (UniProtKB/TrEMBL),   A0A8D0J518 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020957116   ⟸   XM_021101457
- Peptide Label: isoform X1
- UniProtKB: A0A286ZXQ3 (UniProtKB/TrEMBL),   A0A8D0J2K9 (UniProtKB/TrEMBL),   A0A4X1SGI2 (UniProtKB/TrEMBL),   A0A8D1QAA2 (UniProtKB/TrEMBL),   A0A8D0J518 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020957141   ⟸   XM_021101482
- Peptide Label: isoform X2
- UniProtKB: A0A4X1SGI2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000069969   ⟸   ENSSSCT00000078310
Ensembl Acc Id: ENSSSCP00000071907   ⟸   ENSSSCT00000075014
Ensembl Acc Id: ENSSSCP00000036467   ⟸   ENSSSCT00000061065
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000034516 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015029341 UniProtKB/TrEMBL
  ENSSSCG00025076099 UniProtKB/TrEMBL
  ENSSSCG00030068329 UniProtKB/TrEMBL
  ENSSSCG00035016489 UniProtKB/TrEMBL
  ENSSSCG00040059549 UniProtKB/TrEMBL
  ENSSSCG00045009624 UniProtKB/TrEMBL
  ENSSSCG00050075066 UniProtKB/TrEMBL
  ENSSSCG00055010579 UniProtKB/TrEMBL
  ENSSSCG00060005600 UniProtKB/TrEMBL
  ENSSSCG00065047836 UniProtKB/TrEMBL
  ENSSSCG00070000681 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000061065 ENTREZGENE
  ENSSSCT00000061065.2 UniProtKB/TrEMBL
  ENSSSCT00000075014.2 UniProtKB/TrEMBL
  ENSSSCT00000078310.2 UniProtKB/TrEMBL
  ENSSSCT00015038941.1 UniProtKB/TrEMBL
  ENSSSCT00025105259.1 UniProtKB/TrEMBL
  ENSSSCT00030095573.1 UniProtKB/TrEMBL
  ENSSSCT00035021084.1 UniProtKB/TrEMBL
  ENSSSCT00040080940.1 UniProtKB/TrEMBL
  ENSSSCT00045016320.1 UniProtKB/TrEMBL
  ENSSSCT00050102843.1 UniProtKB/TrEMBL
  ENSSSCT00055020715.1 UniProtKB/TrEMBL
  ENSSSCT00060007089.1 UniProtKB/TrEMBL
  ENSSSCT00065065427.1 UniProtKB/TrEMBL
  ENSSSCT00070001282.1 UniProtKB/TrEMBL
  ENSSSCT00070001287.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CDK UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene CDKL1 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASE-LIKE 1 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A286ZXQ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SGI2 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2RCE0_PIG UniProtKB/TrEMBL
  A0A5G2RFV1_PIG UniProtKB/TrEMBL
  A0A8D0J2K9 ENTREZGENE
  A0A8D0J518 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1QAA2 ENTREZGENE
UniProt Secondary A0A8D0J2K9 UniProtKB/TrEMBL
  A0A8D1QAA2 UniProtKB/TrEMBL
VGNC ID VGNC:86510 ENTREZGENE