Rps6ka5 (ribosomal protein S6 kinase A5) - Rat Genome Database

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Gene: Rps6ka5 (ribosomal protein S6 kinase A5) Rattus norvegicus
Analyze
Symbol: Rps6ka5
Name: ribosomal protein S6 kinase A5
RGD ID: 1308336
Description: Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in several processes, including interleukin-1-mediated signaling pathway; protein modification process; and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human RPS6KA5 (ribosomal protein S6 kinase A5); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC314384; mitogen and stress-activated protein kinase 1; Msk1; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26119,828,823 - 120,006,190 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6119,828,846 - 120,006,224 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6119,991,862 - 120,163,014 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.06120,288,522 - 120,459,682 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.06119,623,372 - 119,794,534 (-)NCBIRnor_WKY
Rnor_6.06124,557,892 - 124,735,787 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6124,557,913 - 124,735,778 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06133,782,163 - 133,959,351 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46124,820,623 - 124,999,790 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16124,827,314 - 125,003,586 (-)NCBI
Celera6117,356,574 - 117,533,013 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
all-trans-retinoic acid  (ISO)
arsenite(3-)  (ISO)
avermectin  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
chloroprene  (EXP)
cocaine  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
diclofenac  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
fasudil  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
gallic acid  (ISO)
gentamycin  (EXP)
hexane  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
MeIQx  (ISO)
metformin  (ISO)
methyl methanesulfonate  (ISO)
mifepristone  (EXP)
ML-7  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP,ISO)
nickel sulfate  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
obeticholic acid  (ISO)
oxaliplatin  (EXP)
oxidopamine  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
phenylephrine  (EXP)
pioglitazone  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
Ro 31-8220  (EXP)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
SCH 23390  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
SL-327  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
Y-27632  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)
nucleoplasm  (IBA,ISO)
nucleus  (ISO)
ribosome  (IEA)

References

References - curated
# Reference Title Reference Citation
1. MAPKAP kinases - MKs - two's company, three's a crowd. Gaestel M Nat Rev Mol Cell Biol. 2006 Feb;7(2):120-30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9687510   PMID:9873047   PMID:11994045   PMID:12628924   PMID:12763138   PMID:12773393   PMID:15010469   PMID:15893597   PMID:16531007   PMID:18385332   PMID:18511904   PMID:19197368  
PMID:20018936   PMID:21493629   PMID:22004609   PMID:22082260   PMID:23065332   PMID:24142296   PMID:24349124   PMID:24352802   PMID:30744416   PMID:30919247  


Genomics

Comparative Map Data
Rps6ka5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26119,828,823 - 120,006,190 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6119,828,846 - 120,006,224 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6119,991,862 - 120,163,014 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.06120,288,522 - 120,459,682 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.06119,623,372 - 119,794,534 (-)NCBIRnor_WKY
Rnor_6.06124,557,892 - 124,735,787 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6124,557,913 - 124,735,778 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06133,782,163 - 133,959,351 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46124,820,623 - 124,999,790 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16124,827,314 - 125,003,586 (-)NCBI
Celera6117,356,574 - 117,533,013 (-)NCBICelera
Cytogenetic Map6q32NCBI
RPS6KA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381490,847,861 - 91,060,641 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1490,847,861 - 91,060,641 (-)EnsemblGRCh38hg38GRCh38
GRCh371491,314,205 - 91,526,985 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361490,406,912 - 90,596,746 (-)NCBINCBI36Build 36hg18NCBI36
Build 341490,430,073 - 90,596,746NCBI
Celera1471,385,722 - 71,575,427 (-)NCBICelera
Cytogenetic Map14q32.11NCBI
HuRef1471,512,920 - 71,702,554 (-)NCBIHuRef
CHM1_11491,274,932 - 91,464,763 (-)NCBICHM1_1
T2T-CHM13v2.01485,073,446 - 85,286,084 (-)NCBIT2T-CHM13v2.0
Rps6ka5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912100,514,692 - 100,691,693 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12100,514,698 - 100,693,242 (-)EnsemblGRCm39 Ensembl
GRCm3812100,548,439 - 100,725,328 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12100,548,439 - 100,726,983 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712101,787,988 - 101,963,238 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612100,950,828 - 101,126,078 (-)NCBIMGSCv36mm8
Celera12101,770,330 - 101,946,292 (-)NCBICelera
Cytogenetic Map12ENCBI
Rps6ka5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543813,217,222 - 13,392,674 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543813,218,451 - 13,392,080 (-)NCBIChiLan1.0ChiLan1.0
RPS6KA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11490,840,651 - 91,028,786 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1490,840,655 - 91,028,780 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01471,489,654 - 71,679,250 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
RPS6KA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1861,801,185 - 61,962,846 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl861,802,812 - 61,973,259 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha861,381,750 - 61,551,905 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0862,076,158 - 62,246,525 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl862,052,775 - 62,246,681 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1861,756,580 - 61,926,684 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0861,805,735 - 61,976,310 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0862,135,192 - 62,305,546 (-)NCBIUU_Cfam_GSD_1.0
Rps6ka5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864013,936,110 - 14,130,251 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648817,940,327 - 18,132,970 (-)EnsemblSpeTri2.0
SpeTri2.0NW_00493648817,937,421 - 18,132,845 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS6KA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7112,561,988 - 112,753,564 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17112,561,985 - 112,753,666 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RPS6KA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12468,620,637 - 68,821,996 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2468,619,349 - 68,763,376 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605355,881,279 - 56,081,538 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps6ka5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473411,499,637 - 11,659,536 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473411,499,372 - 11,660,564 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rps6ka5
814 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:514
Count of miRNA genes:270
Interacting mature miRNAs:348
Transcripts:ENSRNOT00000064716
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat

Markers in Region
BE108505  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26119,849,738 - 119,849,896 (+)MAPPERmRatBN7.2
Rnor_6.06124,578,806 - 124,578,963NCBIRnor6.0
Rnor_5.06133,803,077 - 133,803,234UniSTSRnor5.0
RGSC_v3.46124,841,515 - 124,841,672UniSTSRGSC3.4
Celera6117,377,469 - 117,377,626UniSTS
RH 3.4 Map6858.8UniSTS
Cytogenetic Map6q32UniSTS
RH138282  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26119,966,370 - 119,966,506 (+)MAPPERmRatBN7.2
Rnor_6.06124,695,946 - 124,696,081NCBIRnor6.0
Rnor_5.06133,919,525 - 133,919,660UniSTSRnor5.0
RGSC_v3.46124,958,797 - 124,958,932UniSTSRGSC3.4
Celera6117,493,405 - 117,493,540UniSTS
RH 3.4 Map6858.2UniSTS
Cytogenetic Map6q32UniSTS
AU049990  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26119,917,369 - 119,917,536 (+)MAPPERmRatBN7.2
Rnor_6.06124,646,427 - 124,646,593NCBIRnor6.0
Rnor_5.06133,870,702 - 133,870,868UniSTSRnor5.0
RGSC_v3.46124,910,154 - 124,910,320UniSTSRGSC3.4
Celera6117,444,973 - 117,445,139UniSTS
Cytogenetic Map6q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 16 16 1 1 58 22 10 1
Low 3 43 41 41 3 41 7 10 16 35 19 1 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000064716   ⟹   ENSRNOP00000063163
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6119,828,846 - 120,006,144 (-)Ensembl
Rnor_6.0 Ensembl6124,557,913 - 124,735,741 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091693   ⟹   ENSRNOP00000072518
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6119,843,277 - 119,949,175 (-)Ensembl
Rnor_6.0 Ensembl6124,560,659 - 124,735,778 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105060   ⟹   ENSRNOP00000091483
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6119,828,846 - 120,006,224 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107141   ⟹   ENSRNOP00000089479
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6119,828,846 - 119,949,175 (-)Ensembl
RefSeq Acc Id: NM_001108048   ⟹   NP_001101518
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26119,828,846 - 120,006,144 (-)NCBI
Rnor_6.06124,557,913 - 124,735,741 (-)NCBI
Rnor_5.06133,782,163 - 133,959,351 (-)NCBI
RGSC_v3.46124,820,623 - 124,999,790 (-)RGD
Celera6117,356,574 - 117,533,013 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240437   ⟹   XP_006240499
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26119,828,823 - 120,006,185 (-)NCBI
Rnor_6.06124,557,892 - 124,735,787 (-)NCBI
Rnor_5.06133,782,163 - 133,959,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240438   ⟹   XP_006240500
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26119,828,823 - 120,006,186 (-)NCBI
Rnor_6.06124,557,892 - 124,735,787 (-)NCBI
Rnor_5.06133,782,163 - 133,959,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594169   ⟹   XP_017449658
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26119,828,823 - 119,951,182 (-)NCBI
Rnor_6.06124,557,892 - 124,680,278 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017594171   ⟹   XP_017449660
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26119,828,823 - 119,867,313 (-)NCBI
Rnor_6.06124,557,892 - 124,596,530 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112350   ⟹   XP_038968278
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26119,828,823 - 119,922,936 (-)NCBI
RefSeq Acc Id: XM_039112351   ⟹   XP_038968279
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26119,844,071 - 120,006,190 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001101518   ⟸   NM_001108048
- Sequence:
RefSeq Acc Id: XP_006240500   ⟸   XM_006240438
- Peptide Label: isoform X2
- UniProtKB: A0A8I6ABQ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240499   ⟸   XM_006240437
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K366 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449658   ⟸   XM_017594169
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017449660   ⟸   XM_017594171
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000072518   ⟸   ENSRNOT00000091693
RefSeq Acc Id: ENSRNOP00000063163   ⟸   ENSRNOT00000064716
RefSeq Acc Id: XP_038968278   ⟸   XM_039112350
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038968279   ⟸   XM_039112351
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000091483   ⟸   ENSRNOT00000105060
RefSeq Acc Id: ENSRNOP00000089479   ⟸   ENSRNOT00000107141
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K366-F1-model_v2 AlphaFold A0A0G2K366 1-798 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694783
Promoter ID:EPDNEW_R5300
Type:single initiation site
Name:Rps6ka5_1
Description:ribosomal protein S6 kinase A5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06124,735,781 - 124,735,841EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308336 AgrOrtholog
BioCyc Gene G2FUF-36495 BioCyc
Ensembl Genes ENSRNOG00000004362 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000063163.1 UniProtKB/TrEMBL
  ENSRNOP00000072518.2 UniProtKB/TrEMBL
  ENSRNOP00000089479 ENTREZGENE
  ENSRNOP00000089479.1 UniProtKB/TrEMBL
  ENSRNOP00000091483 ENTREZGENE
  ENSRNOP00000091483.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064716.3 UniProtKB/TrEMBL
  ENSRNOT00000091693.2 UniProtKB/TrEMBL
  ENSRNOT00000105060 ENTREZGENE
  ENSRNOT00000105060.1 UniProtKB/TrEMBL
  ENSRNOT00000107141 ENTREZGENE
  ENSRNOT00000107141.1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ribosomal_S6_kinase_II UniProtKB/TrEMBL
  Ser/Thr_prot_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:314384 UniProtKB/TrEMBL
NCBI Gene 314384 ENTREZGENE
Pfam Pkinase UniProtKB/TrEMBL
  Pkinase_C UniProtKB/TrEMBL
PhenoGen Rps6ka5 PhenoGen
PIRSF Ribsml_S6_kin_2 UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TK_X UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A0G2K366 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7D1_RAT UniProtKB/TrEMBL
  A0A8I6ABQ6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZY17_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-04 Rps6ka5  ribosomal protein S6 kinase A5  Rps6ka5  ribosomal protein S6 kinase, polypeptide 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Rps6ka5  ribosomal protein S6 kinase, polypeptide 5   Rps6ka5_predicted  ribosomal protein S6 kinase, polypeptide 5 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rps6ka5_predicted  ribosomal protein S6 kinase, polypeptide 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED