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Gene: Rps6ka5 (ribosomal protein S6 kinase A5) Rattus norvegicus
Symbol: Rps6ka5
Name: ribosomal protein S6 kinase A5
Description: Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including histone-serine phosphorylation; positive regulation of histone modification; and regulation of transcription, DNA-templated. Predicted to localize to the cytoplasm and nucleoplasm. Orthologous to human RPS6KA5 (ribosomal protein S6 kinase A5); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; benzo[a]pyrene; bisphenol A.
Type: protein-coding
Also known as: LOC314384; mitogen and stress-activated protein kinase 1; Msk1; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5
Homo sapiens (human) : RPS6KA5 (ribosomal protein S6 kinase A5)  HGNC  Alliance
Mus musculus (house mouse) : Rps6ka5 (ribosomal protein S6 kinase, polypeptide 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rps6ka5 (ribosomal protein S6 kinase A5)
Pan paniscus (bonobo/pygmy chimpanzee) : RPS6KA5 (ribosomal protein S6 kinase A5)
Canis lupus familiaris (dog) : RPS6KA5 (ribosomal protein S6 kinase A5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rps6ka5 (ribosomal protein S6 kinase A5)
Sus scrofa (pig) : RPS6KA5 (ribosomal protein S6 kinase A5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06124,557,892 - 124,735,787 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06133,782,163 - 133,959,351 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46124,820,623 - 124,999,790 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16124,827,314 - 125,003,586 (-)NCBI
Celera6117,356,574 - 117,533,013 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Rps6ka5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308336
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.