Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: RPS6KA5 (ribosomal protein S6 kinase A5) Homo sapiens
Symbol: RPS6KA5
Name: ribosomal protein S6 kinase A5
Description: Exhibits ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including histone-serine phosphorylation; positive regulation of histone modification; and regulation of transcription, DNA-templated. Localizes to the cytoplasm and nucleoplasm; PARTICIPATES IN mitogen activated protein kinase signaling pathway; neurotrophic factor signaling pathway; p38 MAPK signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 5-(1,4-diazepane-1-sulfonyl)isoquinoline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 90 kDa ribosomal protein S6 kinase 5; MGC1911; MSK1; MSPK1; nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; RLPK; RSK-like protein kinase; RSKL; S6K-alpha-5
Mus musculus (house mouse) : Rps6ka5 (ribosomal protein S6 kinase, polypeptide 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rps6ka5 (ribosomal protein S6 kinase A5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rps6ka5 (ribosomal protein S6 kinase A5)
Pan paniscus (bonobo/pygmy chimpanzee) : RPS6KA5 (ribosomal protein S6 kinase A5)
Canis lupus familiaris (dog) : RPS6KA5 (ribosomal protein S6 kinase A5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rps6ka5 (ribosomal protein S6 kinase A5)
Sus scrofa (pig) : RPS6KA5 (ribosomal protein S6 kinase A5)
Chlorocebus sabaeus (African green monkey) : RPS6KA5 (ribosomal protein S6 kinase A5)
Heterocephalus glaber (naked mole-rat) : Rps6ka5 (ribosomal protein S6 kinase A5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1490,847,861 - 91,060,641 (-)EnsemblGRCh38hg38GRCh38
GRCh381490,847,861 - 91,060,649 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371491,335,086 - 91,526,993 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361490,406,912 - 90,596,746 (-)NCBINCBI36hg18NCBI36
Build 341490,430,073 - 90,596,746NCBI
Celera1471,385,722 - 71,575,427 (-)NCBI
Cytogenetic Map14q32.11NCBI
HuRef1471,512,920 - 71,702,554 (-)NCBIHuRef
CHM1_11491,272,239 - 91,464,763 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RPS6KA5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318046
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.