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Gene: Eif2b2 (eukaryotic translation initiation factor 2B subunit beta) Rattus norvegicus
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Symbol: Eif2b2
Name: eukaryotic translation initiation factor 2B subunit beta
Description: Contributes to guanyl-nucleotide exchange factor activity. Involved in several processes, including nervous system development; response to glucose; and response to heat. Localizes to the axon and eukaryotic translation initiation factor 2B complex. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Orthologous to human EIF2B2 (eukaryotic translation initiation factor 2B subunit beta); PARTICIPATES IN translation initiation pathway; RNA transport pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: eIF-2B GDP-GTP exchange factor subunit beta; eukaryotic translation initiation factor 2B subunit 2; eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD); eukaryotic translation initiation factor 2B, subunit 2 beta; translation initiation factor eIF-2B subunit beta
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06109,044,830 - 109,051,254 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6109,043,880 - 109,051,253 (+)Ensembl
Rnor_5.06116,505,786 - 116,512,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46109,266,354 - 109,272,778 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16109,269,805 - 109,276,234 (+)NCBI
Celera6102,689,874 - 102,696,298 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Eif2b2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620820
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.