Lin52 (lin-52 DREAM MuvB core complex component) - Rat Genome Database
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Gene: Lin52 (lin-52 DREAM MuvB core complex component) Rattus norvegicus
Analyze
Symbol: Lin52
Name: lin-52 DREAM MuvB core complex component
RGD ID: 1306798
Description: Predicted to be involved in transcription, DNA-templated. Predicted to localize to DRM complex. Orthologous to human LIN52 (lin-52 DREAM MuvB core complex component); INTERACTS WITH bisphenol A; endosulfan; 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: lin-52 homolog; lin-52 homolog (C. elegans); LOC362763; RGD1306798; similar to CG15929-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26104,098,818 - 104,199,323 (+)NCBI
Rnor_6.0 Ensembl6108,167,716 - 108,178,508 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06108,167,412 - 108,264,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06117,281,797 - 117,379,146 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,516,945 - 108,601,602 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16108,520,400 - 108,606,606 (+)NCBI
Celera6101,926,888 - 102,023,827 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
DRM complex  (IEA)

Molecular Function

References


Genomics

Comparative Map Data
Lin52
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26104,098,818 - 104,199,323 (+)NCBI
Rnor_6.0 Ensembl6108,167,716 - 108,178,508 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06108,167,412 - 108,264,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06117,281,797 - 117,379,146 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,516,945 - 108,601,602 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16108,520,400 - 108,606,606 (+)NCBI
Celera6101,926,888 - 102,023,827 (+)NCBICelera
Cytogenetic Map6q31NCBI
LIN52
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1474,084,796 - 74,201,235 (+)EnsemblGRCh38hg38GRCh38
GRCh381474,084,867 - 74,201,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371474,551,659 - 74,668,196 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,621,252 - 73,735,491 (+)NCBINCBI36hg18NCBI36
Build 341473,621,420 - 73,736,870NCBI
Celera1454,588,612 - 54,704,404 (+)NCBI
Cytogenetic Map14q24.3NCBI
HuRef1454,718,374 - 54,834,132 (+)NCBIHuRef
CHM1_11474,491,130 - 74,606,659 (+)NCBICHM1_1
Lin52
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,497,974 - 84,593,289 (+)NCBIGRCm39mm39
GRCm39 Ensembl1284,498,196 - 84,592,919 (+)Ensembl
GRCm381284,451,508 - 84,531,533 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,451,422 - 84,546,145 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,792,458 - 85,872,483 (+)NCBIGRCm37mm9NCBIm37
MGSCv361285,341,256 - 85,421,281 (+)NCBImm8
Celera1285,907,021 - 85,987,004 (+)NCBICelera
Cytogenetic Map12D1NCBI
Lin52
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555231,250,551 - 1,344,213 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555231,250,551 - 1,344,434 (-)NCBIChiLan1.0ChiLan1.0
LIN52
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11473,496,037 - 73,612,421 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1473,496,037 - 73,612,416 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01454,643,652 - 54,760,308 (+)NCBIMhudiblu_PPA_v0panPan3
LIN52
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl847,304,759 - 47,413,575 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1847,304,607 - 47,415,543 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Lin52
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364883,340,888 - 3,448,338 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIN52
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl797,382,354 - 97,403,859 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1797,382,020 - 97,491,672 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27103,136,529 - 103,337,798 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LIN52
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12451,296,748 - 51,406,176 (+)NCBI
Lin52
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473427,404,948 - 27,499,041 (-)NCBI

Position Markers
RH143171  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.06108,221,434 - 108,221,714NCBIRnor6.0
Rnor_5.06117,324,395 - 117,324,675UniSTSRnor5.0
RGSC_v3.46108,574,100 - 108,574,380UniSTSRGSC3.4
Celera6101,980,832 - 101,981,112UniSTS
RH 3.4 Map6742.4UniSTS
Cytogenetic Map6q31UniSTS
D14S1176  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.06108,219,208 - 108,219,369NCBIRnor6.0
Rnor_5.06117,326,419 - 117,326,580UniSTSRnor5.0
RGSC_v3.46108,570,091 - 108,570,252UniSTSRGSC3.4
Celera6101,978,701 - 101,978,862UniSTS
Cytogenetic Map6q31UniSTS
fb82h10.x1  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.46108,537,191 - 108,538,648UniSTSRGSC3.4
RGSC_v3.46108,537,171 - 108,538,648UniSTSRGSC3.4
Celera6101,947,275 - 101,948,752UniSTS
Celera6101,947,295 - 101,948,752UniSTS
Cytogenetic Map6q31UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6104381930138066274Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)686422697115379601Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)67009971115379601Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)688507712133507712Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)648432758108268790Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)6101207574147991367Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6104363890147991367Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)675449871120449871Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)691703409136703409Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)697949772133849286Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)689631358134631358Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)689631358134631358Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)675623277120276465Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6108154445133849286Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)675623277136426962Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)687418448111129520Rat
1581550Pur8Proteinuria QTL 8total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)675623393136142742Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)671206251116206251Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)675623393136142742Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)62537030111715717Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)699273921144792678Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)675623277120623277Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)688996335139410483Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)676902247114203334Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)675623277136143011Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)684763275108464097Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)684763275108464097Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (VE) (CMO:0000132)692879510137879510Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)693706176111134673Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)699273921144273921Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)666129520111129520Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:35
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000064426
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 24 30 14 19 14 4 6 74 35 40 11 4
Low 1 19 27 27 27 4 5 1 4
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000064426   ⟹   ENSRNOP00000061629
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6108,167,716 - 108,178,508 (+)Ensembl
RefSeq Acc Id: XM_001056671   ⟹   XP_001056671
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,920 - 102,009,469 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006225847   ⟹   XP_006225909
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,888 - 102,022,161 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006225849   ⟹   XP_006225911
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,916 - 102,009,469 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006225851   ⟹   XP_006225913
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,917 - 101,942,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006225852   ⟹   XP_006225914
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,920 - 101,942,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240356   ⟹   XP_006240418
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,194,229 (+)NCBI
Rnor_6.06108,167,412 - 108,262,793 (+)NCBI
Rnor_5.06117,281,797 - 117,379,146 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240358   ⟹   XP_006240420
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,181,539 (+)NCBI
Rnor_6.06108,167,440 - 108,250,099 (+)NCBI
Rnor_5.06117,281,797 - 117,379,146 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764889   ⟹   XP_008763111
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,114,692 (+)NCBI
Rnor_6.06108,167,441 - 108,183,039 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764890   ⟹   XP_008763112
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,114,685 (+)NCBI
Rnor_6.06108,167,444 - 108,183,044 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594487   ⟹   XP_017449976
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,149,372 (+)NCBI
Rnor_6.06108,167,421 - 108,215,487 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594488   ⟹   XP_017449977
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,149,372 (+)NCBI
Rnor_6.06108,167,423 - 108,215,487 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594489   ⟹   XP_017449978
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,145,675 (+)NCBI
Rnor_6.06108,167,423 - 108,207,702 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017603268   ⟹   XP_017458757
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,897 - 101,974,980 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017603269   ⟹   XP_017458758
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,899 - 101,974,980 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017603270   ⟹   XP_017458759
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,899 - 101,967,195 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039113308   ⟹   XP_038969236
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,194,229 (+)NCBI
RefSeq Acc Id: XM_343089   ⟹   XP_343090
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,181,539 (+)NCBI
Rnor_6.06108,167,444 - 108,250,099 (+)NCBI
Rnor_5.06117,281,797 - 117,379,146 (-)NCBI
RGSC_v3.46108,516,945 - 108,601,602 (+)RGD
Sequence:
RefSeq Acc Id: XR_001838493
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,199,323 (+)NCBI
Rnor_6.06108,167,412 - 108,264,457 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001844108
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,888 - 102,023,825 (+)NCBI
Sequence:
RefSeq Acc Id: XR_347392
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,888 - 102,023,827 (+)NCBI
Sequence:
RefSeq Acc Id: XR_347394
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera6101,926,892 - 102,023,826 (+)NCBI
Sequence:
RefSeq Acc Id: XR_354978
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,199,323 (+)NCBI
Rnor_6.06108,167,412 - 108,264,459 (+)NCBI
Rnor_5.06117,281,797 - 117,379,146 (-)NCBI
Sequence:
RefSeq Acc Id: XR_354980
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26104,098,818 - 104,199,322 (+)NCBI
Rnor_6.06108,167,416 - 108,264,458 (+)NCBI
Rnor_5.06117,281,797 - 117,379,146 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_001056671   ⟸   XM_001056671
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_343090   ⟸   XM_343089
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006225909   ⟸   XM_006225847
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006225911   ⟸   XM_006225849
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006225913   ⟸   XM_006225851
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006225914   ⟸   XM_006225852
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006240418   ⟸   XM_006240356
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006240420   ⟸   XM_006240358
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008763111   ⟸   XM_008764889
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008763112   ⟸   XM_008764890
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_017458757   ⟸   XM_017603268
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017458758   ⟸   XM_017603269
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017458759   ⟸   XM_017603270
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017449976   ⟸   XM_017594487
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017449977   ⟸   XM_017594488
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017449978   ⟸   XM_017594489
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000061629   ⟸   ENSRNOT00000064426
RefSeq Acc Id: XP_038969236   ⟸   XM_039113308
- Peptide Label: isoform X2

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694732
Promoter ID:EPDNEW_R5252
Type:single initiation site
Name:Lin52_1
Description:lin-52 DREAM MuvB core complex component
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06108,167,713 - 108,167,773EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306798 AgrOrtholog
Ensembl Genes ENSRNOG00000043441 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000061629 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064426 UniProtKB/TrEMBL
InterPro DREAM_Lin52 UniProtKB/TrEMBL
NCBI Gene 362763 ENTREZGENE
PANTHER PTHR31489 UniProtKB/TrEMBL
Pfam Ret_tiss UniProtKB/TrEMBL
PhenoGen Lin52 PhenoGen
UniProt D4A6T8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-23 Lin52  lin-52 DREAM MuvB core complex component  Lin52  lin-52 homolog (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Lin52  lin-52 homolog (C. elegans)  RGD1306798_predicted  similar to CG15929-PA (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1306798_predicted  similar to CG15929-PA (predicted)  LOC362763_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362763_predicted  similar to CG15929-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL