Gene: Golga5 (golgin A5) Rattus norvegicus
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Symbol:
Golga5
Name:
golgin A5
Description:
Exhibits Rab GTPase binding activity and protein binding activity, bridging. Involved in Golgi organization and retrograde transport, vesicle recycling within Golgi. Localizes to the COPI-coated vesicle membrane and Golgi apparatus. Orthologous to human GOLGA5 (golgin A5); INTERACTS WITH bisphenol A; flutamide; methapyrilene.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
golgi autoantigen, golgin subfamily a, 5; golgin subfamily A member 5; golgin-84; Ret-II
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
GOLGA5 (golgin A5) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Golga5 (golgi autoantigen, golgin subfamily a, 5) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Golga5 (golgin A5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
GOLGA5 (golgin A5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
GOLGA5 (golgin A5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Golga5 (golgin A5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
GOLGA5 (golgin A5) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
GOLGA5 (golgin A5)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):
Golga5 (golgi autoantigen, golgin subfamily a, 5)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
golga5 (golgin A5)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Caenorhabditis elegans (roundworm):
T24B1.1
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):
Golgin84
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 6 126,350,572 - 126,378,735 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 6 126,353,223 - 126,378,610 (+) Ensembl Rnor_5.0 6 135,561,133 - 135,589,807 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 6 126,740,320 - 126,765,513 (+) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 6 126,744,066 - 126,769,260 (+) NCBI Celera 6 119,103,910 - 119,128,964 (+) NCBI Celera Cytogenetic Map 6 q32 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
RGD Manual Annotations
Thyroid Neoplasms ISO RGD:1317779 1599259 reciprocal translocation resulting in fusion of GOLGA5 with the RET oncogene found in radioactivity-induced thyroid carcinomas RGD
Gene-Chemical Interaction Annotations
17beta-estradiol increases expression ISO RGD:1317779 6480464 Estradiol results in increased expression of GOLGA5 mRNA CTD PMID:16514628 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1317780 6480464 Tetrachlorodibenzodioxin affects the expression of GOLGA5 mRNA CTD PMID:21570461 2-hydroxypropanoic acid decreases expression ISO RGD:1317779 6480464 Lactic Acid results in decreased expression of GOLGA5 mRNA CTD PMID:30851411 afimoxifene decreases expression ISO RGD:1317779 6480464 afimoxifene results in decreased expression of GOLGA5 mRNA CTD PMID:16514628 aflatoxin B1 decreases methylation ISO RGD:1317779 6480464 Aflatoxin B1 results in decreased methylation of GOLGA5 gene CTD PMID:27153756 Aroclor 1254 decreases expression ISO RGD:1317780 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of GOLGA5 mRNA CTD PMID:23650126 benzo[a]pyrene increases expression ISO RGD:1317780 6480464 Benzo(a)pyrene results in increased expression of GOLGA5 mRNA CTD PMID:22228805 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GOLGA5 mRNA CTD PMID:25181051 carbon nanotube increases expression ISO RGD:1317780 6480464 Nanotubes, Carbon analog results in increased expression of GOLGA5 mRNA, Nanotubes, Carbon results in increased expression of GOLGA5 mRNA CTD PMID:25620056 copper(II) sulfate decreases expression ISO RGD:1317779 6480464 Copper Sulfate results in decreased expression of GOLGA5 mRNA CTD PMID:19549813 cyclosporin A increases expression ISO RGD:1317779 6480464 Cyclosporine results in increased expression of GOLGA5 mRNA CTD PMID:20106945 more ... dicrotophos decreases expression ISO RGD:1317779 6480464 dicrotophos results in decreased expression of GOLGA5 mRNA CTD PMID:28302478 disodium selenite increases expression ISO RGD:1317779 6480464 Sodium Selenite results in increased expression of GOLGA5 mRNA CTD PMID:18175754 ethanol affects splicing ISO RGD:1317780 6480464 Ethanol affects the splicing of GOLGA5 mRNA CTD PMID:30319688 fluoranthene multiple interactions ISO RGD:1317780 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of GOLGA5 mRNA CTD PMID:28329830 flutamide increases expression EXP 6480464 Flutamide results in increased expression of GOLGA5 mRNA CTD PMID:24136188 fulvestrant decreases expression ISO RGD:1317779 6480464 fulvestrant results in decreased expression of GOLGA5 mRNA CTD PMID:16514628 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of GOLGA5 mRNA CTD PMID:30467583 nickel atom decreases expression ISO RGD:1317779 6480464 Nickel results in decreased expression of GOLGA5 mRNA CTD PMID:23195993 paracetamol affects expression ISO RGD:1317780 6480464 Acetaminophen affects the expression of GOLGA5 mRNA CTD PMID:17562736 propiconazole increases expression ISO RGD:1317780 6480464 propiconazole results in increased expression of GOLGA5 mRNA CTD PMID:21278054 rac-lactic acid decreases expression ISO RGD:1317779 6480464 Lactic Acid results in decreased expression of GOLGA5 mRNA CTD PMID:30851411 raloxifene decreases expression ISO RGD:1317779 6480464 Raloxifene Hydrochloride results in decreased expression of GOLGA5 mRNA CTD PMID:16514628 Soman decreases expression EXP 6480464 Soman results in decreased expression of GOLGA5 mRNA CTD PMID:19281266 thapsigargin increases expression ISO RGD:1317779 6480464 Thapsigargin results in increased expression of GOLGA5 mRNA CTD PMID:22378314 tungsten decreases expression ISO RGD:1317780 6480464 Tungsten results in decreased expression of GOLGA5 mRNA CTD PMID:30912803 tunicamycin increases expression ISO RGD:1317779 6480464 Tunicamycin results in increased expression of GOLGA5 mRNA CTD PMID:22378314 valproic acid decreases methylation ISO RGD:1317779 6480464 Valproic Acid results in decreased methylation of GOLGA5 gene CTD PMID:29154799 valproic acid increases expression ISO RGD:1317780 6480464 Valproic Acid results in increased expression of GOLGA5 mRNA CTD PMID:21427059 valproic acid decreases expression ISO RGD:1317779 6480464 Valproic Acid results in decreased expression of GOLGA5 mRNA CTD PMID:23179753 valproic acid affects expression ISO RGD:1317779 6480464 Valproic Acid affects the expression of GOLGA5 mRNA CTD PMID:25979313 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of GOLGA5 mRNA CTD PMID:23034163
Gene Ontology Annotations
Biological Process Golgi organization IDA 1599261 RGD Golgi organization IBA PANTHER:PTN000352326 more ... 13792537 PMID:21873635 GO_Central Golgi organization ISS UniProtKB:Q8TBA6 1600115 GO_REF:0000024 UniProt GO_REF:0000024 Golgi organization IEA UniProtKB:Q8TBA6 , ensembl:ENSP000001634161600115 GO_REF:0000107 Ensembl GO_REF:0000107 Golgi organization ISO RGD:1317779 1624291 (PMID:12538640) RGD PMID:12538640 Golgi vesicle transport ISO RGD:1317779 1624291 (PMID:12538640) RGD PMID:12538640 Golgi vesicle transport ISS UniProtKB:Q8TBA6 1600115 GO_REF:0000024 UniProt GO_REF:0000024 Golgi vesicle transport IEA UniProtKB:Q8TBA6 , ensembl:ENSP000001634161600115 GO_REF:0000107 Ensembl GO_REF:0000107 retrograde transport, vesicle recycling within Golgi IMP 1599272 RGD retrograde transport, vesicle recycling within Golgi IBA PANTHER:PTN000352326 , RGD:1308163 13792537 PMID:21873635 GO_Central Cellular Component cis-Golgi network ISO RGD:1317779 1624291 (PMID:12538640) RGD PMID:12538640 cis-Golgi network IEA UniProtKB:Q8TBA6 , ensembl:ENSP000001634161600115 GO_REF:0000107 Ensembl GO_REF:0000107 COPI-coated vesicle membrane IDA 1599272 RGD Golgi apparatus ISO RGD:1317779 1624291 (PMID:9915833) RGD GO_REF:0000052, PMID:9915833 Golgi apparatus ISS UniProtKB:Q8TBA6 1600115 GO_REF:0000024 UniProt GO_REF:0000024 Golgi cis cisterna IDA 1599261 RGD Golgi cisterna ISO RGD:1317779 1624291 (PMID:12538640) RGD PMID:12538640 Golgi cisterna IBA PANTHER:PTN000352326 , UniProtKB:Q8TBA6 13792537 PMID:21873635 GO_Central Golgi cisterna IBA PANTHER:PTN000352326 more ... 13792537 PMID:21873635 GO_Central Golgi cisterna IEA UniProtKB:Q8TBA6 , ensembl:ENSP000001634161600115 GO_REF:0000107 Ensembl GO_REF:0000107 Golgi medial cisterna IDA 1599261 RGD Golgi membrane IDA 1599261 RGD Golgi membrane IBA MGI:MGI:1351475 more ... 13792537 PMID:21873635 GO_Central Golgi membrane IEA UniProtKB:Q9QYE6 , ensembl:ENSMUSP000000216091600115 GO_REF:0000107 Ensembl GO_REF:0000107 Golgi membrane ISO RGD:1317780 1624291 (MGI:MGI:1329272, PMID:9915833) RGD MGI:MGI:1329272 , PMID:9915833 Golgi trans cisterna IDA 1599261 RGD integral component of membrane ISO RGD:1317779 1624291 (PMID:9915833) RGD PMID:9915833 integral component of membrane IEA UniProtKB-KW:KW-0812 1600115 GO_REF:0000037 UniProt GO_REF:0000037 integral component of membrane IEA UniProtKB:Q8TBA6 , ensembl:ENSP000001634161600115 GO_REF:0000107 Ensembl GO_REF:0000107 Molecular Function protein binding ISO RGD:1317780 1624291 UniProtKB:Q99N72 (MGI:MGI:3688344 , PMID:15102471) RGD MGI:MGI:3688344 , PMID:15102471 protein binding, bridging IPI RGD:620618 1599272 RGD protein homodimerization activity ISO RGD:1317779 1624291 UniProtKB:Q8TBA6 (PMID:9915833) RGD PMID:9915833 protein homodimerization activity ISS UniProtKB:Q8TBA6 1600115 GO_REF:0000024 UniProt GO_REF:0000024 protein homodimerization activity IEA UniProtKB:Q8TBA6 , ensembl:ENSP000001634161600115 GO_REF:0000107 Ensembl GO_REF:0000107 Rab GTPase binding IDA 1599261 RGD Rab GTPase binding IEA UniProtKB:Q8TBA6 , ensembl:ENSP000001634161600115 GO_REF:0000107 Ensembl GO_REF:0000107 Rab GTPase binding ISO RGD:1317779 1624291 (PMID:12538640) RGD PMID:12538640
731173 Uae22 Urinary albumin excretion QTL 22 10.1 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 6 68781170 147991367 Rat 2290393 Uae37 Urinary albumin excretion QTL 37 0.0001 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 6 68781170 147991367 Rat 724536 Uae7 Urinary albumin excretion QTL 7 3.5 urine albumin amount (VT:0002871) urine albumin level (CMO:0000130) 6 75623277 136143011 Rat 1331799 Bp211 Blood pressure QTL 211 3.66407 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 6 75623277 136426962 Rat 1581550 Pur8 Proteinuria QTL 8 total urine protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 6 75623393 136142742 Rat 1581563 Uae33 Urinary albumin excretion QTL 33 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 6 75623393 136142742 Rat 738034 Anxrr5 Anxiety related response QTL 5 5.9 exploratory behavior trait (VT:0010471) percentage of entries into a discrete space in an experimental apparatus (CMO:0000961) 6 88507712 133507712 Rat 724513 Uae14 Urinary albumin excretion QTL 14 6.5 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 6 88996335 139410483 Rat 10054138 Gmadr3 Adrenal mass QTL 3 3.68 0.00045 adrenal gland mass (VT:0010420) both adrenal glands wet weight (CMO:0000164) 6 89631358 134631358 Rat 10054123 Srcrt6 Stress Responsive Cort QTL 6 2.5 0.0043 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 6 89631358 134631358 Rat 1300076 Glom8 Glomerulus QTL 8 7 0.000000009 kidney glomerulus morphology trait (VT:0005325) count of superficial glomeruli directly contacting the kidney surface (CMO:0001001) 6 91703409 136703409 Rat 2303624 Vencon5 Ventilatory control QTL 5 4.45 respiration trait (VT:0001943) minute ventilation (VE) (CMO:0000132) 6 92879510 137879510 Rat 1331725 Bp212 Blood pressure QTL 212 3.52475 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 6 97949772 133849286 Rat 12801411 Schws8 Schwannoma susceptibility QTL 8 nervous system integrity trait (VT:0010566) percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017) 6 99273921 144273921 Rat 61414 Pia3 Pristane induced arthritis QTL 3 4.5 joint integrity trait (VT:0010548) post-insult time to onset of experimental arthritis (CMO:0001450) 6 99273921 144792678 Rat 8552796 Vie3 Viral induced encephalitis QTL 3 2.6 brain integrity trait (VT:0010579) encephalitis incidence/prevalence measurement (CMO:0002361) 6 101207574 147991367 Rat 1358355 Srcrt4 Stress Responsive Cort QTL 4 6.39 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 6 104363890 147991367 Rat 2313399 Anxrr28 Anxiety related response QTL 28 aggression-related behavior trait (VT:0015014) tameness/aggressiveness composite score (CMO:0002136) 6 104381930 138066274 Rat 1331797 Bp213 Blood pressure QTL 213 3.291 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 6 108154445 133849286 Rat 4145118 Mcs26 Mammary carcinoma susceptibility QTL 26 0.0001 mammary gland integrity trait (VT:0010552) post-insult time to mammary tumor formation (CMO:0000345) 6 111134524 138065254 Rat 737976 Pia24 Pristane induced arthritis QTL 24 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 6 117355600 147991367 Rat 1298087 Iddm18 Insulin dependent diabetes mellitus QTL 18 0.0001 urine glucose amount (VT:0001758) percentage of study population developing diabetes mellitus during a period of time (CMO:0001114) 6 121224054 135658578 Rat
Predicted Target Of
Count of predictions: 94 Count of miRNA genes: 86 Interacting mature miRNAs: 89 Transcripts: ENSRNOT00000010385 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
Gene-Chemical Interaction Annotations
