Ngb (neuroglobin) - Rat Genome Database

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Gene: Ngb (neuroglobin) Rattus norvegicus
Analyze
Symbol: Ngb
Name: neuroglobin
RGD ID: 621461
Description: Predicted to enable oxygen carrier activity. Involved in several processes, including aging; negative regulation of hydrogen peroxide-induced cell death; and visual perception. Located in mitochondrion; neuron projection; and perikaryon. Used to study transient cerebral ischemia. Biomarker of Alzheimer's disease; encephalitis; retinal ischemia; and transient cerebral ischemia. Orthologous to human NGB (neuroglobin); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; barium sulfate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Glnh; globin h
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26106,744,378 - 106,749,830 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl6106,744,378 - 106,749,830 (-)Ensembl
Rnor_6.06111,126,259 - 111,131,699 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,126,261 - 111,132,320 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06120,412,241 - 120,417,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46111,231,188 - 111,236,255 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16111,234,718 - 111,239,786 (-)NCBI
Celera6104,565,839 - 104,571,131 (-)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Hundahl C, etal., Brain Res. 2006 Apr 26;1085(1):19-27. Epub 2006 May 2.
3. Hundahl CA, etal., Neuroendocrinology. 2008;88(3):183-98. doi: 10.1159/000135617. Epub 2008 May 29.
4. Lechauve C, etal., Biochim Biophys Acta. 2012 Dec;1823(12):2261-73. doi: 10.1016/j.bbamcr.2012.09.009. Epub 2012 Oct 2.
5. Li L, etal., Mol Neurobiol. 2014 Feb;49(1):149-62. doi: 10.1007/s12035-013-8506-7. Epub 2013 Aug 1.
6. Li RC, etal., Brain Res. 2006 Jun 22;1096(1):173-9. Epub 2006 Jun 5.
7. Li RC, etal., Brain Res. 2008 Jan 23;1190:159-66. Epub 2007 Nov 22.
8. Li WD, etal., Cell Mol Neurobiol. 2014 Mar;34(2):247-55. doi: 10.1007/s10571-013-0008-7. Epub 2013 Nov 27.
9. Liu C, etal., Zhonghua Shao Shang Za Zhi. 2009 Jun;25(3):222-6.
10. Melgarejo-Gutierrez M, etal., Neuroreport. 2013 Feb 13;24(3):120-5. doi: 10.1097/WNR.0b013e32835d4b74.
11. MGD data from the GO Consortium
12. NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Ramser K, etal., Appl Spectrosc. 2012 Dec;66(12):1454-60. doi: 10.1366/12-06670.
14. RGD automated data pipeline
15. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. RGD automated import pipeline for gene-chemical interactions
17. RGD comprehensive gene curation
18. Shang A, etal., Neurol Sci. 2012 Jun;33(3):551-8. doi: 10.1007/s10072-011-0772-4. Epub 2011 Sep 14.
19. Shi SY, etal., Int J Ophthalmol. 2011;4(4):393-5. doi: 10.3980/j.issn.2222-3959.2011.04.14. Epub 2011 Aug 18.
20. Sun Y, etal., Neurobiol Aging. 2005 Feb;26(2):275-8.
21. Sun Y, etal., Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3497-500. Epub 2003 Mar 5.
22. Xie YN, etal., Zhen Ci Yan Jiu. 2012 Oct;37(5):380-4.
23. Zara S, etal., Gerontology. 2013;59(3):250-60. doi: 10.1159/000346445. Epub 2013 Feb 20.
24. Zhang C, etal., Biochem Biophys Res Commun 2002 Feb 8;290(5):1411-9.
25. Zhang CG, etal., Yi Chuan Xue Bao 2001 Nov;28(11):997-1001.
Additional References at PubMed
PMID:8889548   PMID:11029004   PMID:15193759   PMID:16683692   PMID:16796995   PMID:17560688   PMID:17576199   PMID:18451642   PMID:19327369   PMID:19536481   PMID:20187147   PMID:20211612  
PMID:20230802   PMID:20476562   PMID:21054965   PMID:21767627   PMID:22009023   PMID:22472608   PMID:22664218   PMID:22887765   PMID:23180278   PMID:23639750   PMID:23673310   PMID:24145836  
PMID:24491879   PMID:24747803   PMID:25557405   PMID:25636685   PMID:26400308   PMID:26646387   PMID:26983282   PMID:28359933   PMID:28829495   PMID:29802248   PMID:32205448  


Genomics

Comparative Map Data
Ngb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26106,744,378 - 106,749,830 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl6106,744,378 - 106,749,830 (-)Ensembl
Rnor_6.06111,126,259 - 111,131,699 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,126,261 - 111,132,320 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06120,412,241 - 120,417,508 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46111,231,188 - 111,236,255 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16111,234,718 - 111,239,786 (-)NCBI
Celera6104,565,839 - 104,571,131 (-)NCBICelera
Cytogenetic Map6q31NCBI
NGB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381477,265,483 - 77,271,206 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1477,265,483 - 77,271,206 (-)EnsemblGRCh38hg38GRCh38
GRCh371477,731,826 - 77,737,549 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361476,801,587 - 76,807,408 (-)NCBINCBI36hg18NCBI36
Build 341476,801,580 - 76,807,408NCBI
Celera1457,770,473 - 57,776,215 (-)NCBI
Cytogenetic Map14q24.3NCBI
HuRef1457,898,325 - 57,904,062 (-)NCBIHuRef
CHM1_11477,671,361 - 77,677,104 (-)NCBICHM1_1
T2T-CHM13v2.01471,474,790 - 71,480,551 (-)NCBI
Ngb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391287,144,305 - 87,149,313 (-)NCBIGRCm39mm39
GRCm39 Ensembl1287,144,305 - 87,149,313 (-)Ensembl
GRCm381287,097,531 - 87,102,539 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1287,097,531 - 87,102,539 (-)EnsemblGRCm38mm10GRCm38
MGSCv371288,438,481 - 88,443,489 (-)NCBIGRCm37mm9NCBIm37
MGSCv361287,986,634 - 87,991,642 (-)NCBImm8
Celera1288,562,002 - 88,567,162 (-)NCBICelera
Cytogenetic Map12D2NCBI
Ngb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554381,170,888 - 1,175,978 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554381,170,888 - 1,175,978 (-)NCBIChiLan1.0ChiLan1.0
NGB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11477,020,274 - 77,025,983 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1477,020,274 - 77,025,983 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01457,818,491 - 57,824,196 (-)NCBIMhudiblu_PPA_v0panPan3
NGB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1850,081,960 - 50,086,071 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl850,081,960 - 50,085,435 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha849,769,803 - 49,773,792 (-)NCBI
ROS_Cfam_1.0850,314,590 - 50,325,270 (-)NCBI
ROS_Cfam_1.0 Ensembl850,315,118 - 50,319,630 (-)Ensembl
UMICH_Zoey_3.1849,978,294 - 49,982,287 (-)NCBI
UNSW_CanFamBas_1.0850,001,322 - 50,005,311 (-)NCBI
UU_Cfam_GSD_1.0850,399,520 - 50,403,524 (-)NCBI
Ngb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864025,969,328 - 25,974,879 (+)NCBI
SpeTri2.0NW_0049364886,094,089 - 6,098,876 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NGB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7100,340,939 - 100,346,438 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17100,341,974 - 100,346,263 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27106,610,972 - 106,615,261 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NGB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12454,510,877 - 54,518,535 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605342,711,096 - 42,716,772 (-)NCBIVero_WHO_p1.0
Ngb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473424,640,181 - 24,647,243 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473424,640,389 - 24,645,041 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH143985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26106,744,474 - 106,744,593 (+)MAPPERmRatBN7.2
Rnor_6.06111,126,356 - 111,126,474NCBIRnor6.0
Rnor_5.06120,412,338 - 120,412,456UniSTSRnor5.0
RGSC_v3.46111,231,284 - 111,231,402UniSTSRGSC3.4
Celera6104,565,936 - 104,566,054UniSTS
RH 3.4 Map6743.6UniSTS
Cytogenetic Map6q31UniSTS
NGB  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26106,746,842 - 106,747,639 (+)MAPPERmRatBN7.2
Rnor_6.06111,128,724 - 111,129,520NCBIRnor6.0
Rnor_5.06120,414,706 - 120,415,502UniSTSRnor5.0
RGSC_v3.46111,233,652 - 111,234,448UniSTSRGSC3.4
Celera6104,568,304 - 104,569,100UniSTS
Cytogenetic Map6q31UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:480
Count of miRNA genes:229
Interacting mature miRNAs:276
Transcripts:ENSRNOT00000016057
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1
Low 3 13 5 61 22 36 11
Below cutoff 39 24 21 13 21 7 10 12 13 5 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000016057   ⟹   ENSRNOP00000016057
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6106,744,378 - 106,749,830 (-)Ensembl
Rnor_6.0 Ensembl6111,126,261 - 111,132,320 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000081727   ⟹   ENSRNOP00000073109
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6111,127,246 - 111,131,271 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085112   ⟹   ENSRNOP00000072994
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6111,127,701 - 111,128,735 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108396   ⟹   ENSRNOP00000078847
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6106,746,925 - 106,749,830 (-)Ensembl
RefSeq Acc Id: NM_033359   ⟹   NP_203523
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26106,744,378 - 106,749,830 (-)NCBI
Rnor_6.06111,126,259 - 111,131,699 (-)NCBI
Rnor_5.06120,412,241 - 120,417,508 (-)NCBI
RGSC_v3.46111,231,188 - 111,236,255 (-)RGD
Celera6104,565,839 - 104,571,131 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_203523   ⟸   NM_033359
- UniProtKB: Q99JA8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016057   ⟸   ENSRNOT00000016057
RefSeq Acc Id: ENSRNOP00000072994   ⟸   ENSRNOT00000085112
RefSeq Acc Id: ENSRNOP00000073109   ⟸   ENSRNOT00000081727
RefSeq Acc Id: ENSRNOP00000078847   ⟸   ENSRNOT00000108396
Protein Domains
GLOBIN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99JA8-F1-model_v2 AlphaFold Q99JA8 1-151 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621461 AgrOrtholog
BioCyc Gene G2FUF-36728 BioCyc
Ensembl Genes ENSRNOG00000011719 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000016057 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000072994 UniProtKB/TrEMBL
  ENSRNOP00000073109 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016057 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000081727 UniProtKB/TrEMBL
  ENSRNOT00000085112 UniProtKB/TrEMBL
Gene3D-CATH 1.10.490.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Globin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Globin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Globin/Proto UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:85382 UniProtKB/Swiss-Prot
NCBI Gene 85382 ENTREZGENE
Pfam Globin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ngb PhenoGen
PROSITE GLOBIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46458 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JSL1_RAT UniProtKB/TrEMBL
  A0A0G2K4D1_RAT UniProtKB/TrEMBL
  A0A0G2K4N3_RAT UniProtKB/TrEMBL
  NGB_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8VH38 UniProtKB/Swiss-Prot
  Q99N62 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Ngb  neuroglobin      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Ngb  neuroglobin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in cerebral cortex, hippocampus, thalamus, hypothalamus, olfactory bulb, and cerebellum 625434
gene_protein 151 amino acid protein 729218