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Strain: SS/JrMco

Symbol: SS/JrMco
Strain: SS/Jr
Substrain: Mco
Full Name: Dahl salt-sensitive (SS/Jr) rats
RGD ID: 724573
RRID: RGD_724573
Ontology ID: RS:0000924
Type: inbred
Source: Medical College of Ohio, Toledo, Ohio, USA
Origin: In the 1960s, Dahl selectively bred rats for sensitivity (SS rats) to the hypertensive effect of high-salt diet.
Last Known Status: Unknown





References


Region

Strain QTL Data
Symbol Name Trait
Cm16 Cardiac mass QTL 16 heart mass   (VT:0007028)    
Cm17 Cardiac mass QTL 17 heart mass   (VT:0007028)    
Cm18 Cardiac mass QTL 18 heart mass   (VT:0007028)    
Cm19 Cardiac mass QTL 19 heart mass   (VT:0007028)    
Cm20 Cardiac mass QTL 20 heart mass   (VT:0007028)    
Cm21 Cardiac mass QTL 21 heart mass   (VT:0007028)    
Kidm1 Kidney mass QTL 1 kidney mass   (VT:0002707)    
Kidm2 Kidney mass QTL 2 kidney mass   (VT:0002707)    
Kidm3 Kidney mass QTL 3 kidney mass   (VT:0002707)    
Pur2 Proteinuria QTL 2 urine protein amount   (VT:0005160)    
Uae10 Urinary albumin excretion QTL 10 urine albumin amount   (VT:0002871)    
Uae11 Urinary albumin excretion QTL 11 urine albumin amount   (VT:0002871)    
Uae12 Urinary albumin excretion QTL 12 urine albumin amount   (VT:0002871)    
Uae5 Urinary albumin excretion QTL 5 urine albumin amount   (VT:0002871)    
Uae6 Urinary albumin excretion QTL 6 urine albumin amount   (VT:0002871)    
Uae7 Urinary albumin excretion QTL 7 urine albumin amount   (VT:0002871)    
Uae8 Urinary albumin excretion QTL 8 urine albumin amount   (VT:0002871)    
Uae9 Urinary albumin excretion QTL 9 urine albumin amount   (VT:0002871)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Besides fulminant hypertension, these rats on high-salt diet develop progressive proteinuria and severe renal vascular and glomerular lesions and associated renal tubular lesions. 634617