Gene: Actn1 (actinin, alpha 1) Rattus norvegicus
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Symbol: Actn1
Name: actinin, alpha 1
Description: ENCODES a protein that exhibits protein domain specific binding; actin filament binding (ortholog); alpha-actinin binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); actin filament network formation (ortholog); actin filament organization (ortholog); PARTICIPATES IN E-cadherin signaling pathway; syndecan signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); platelet-type bleeding disorder 15 (ortholog); FOUND IN cortical actin cytoskeleton; cytoplasm; dendritic spine; INTERACTS WITH (R)-adrenaline; 1-naphthyl isothiocyanate; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-actinin cytoskeletal isoform; alpha-actinin-1; F-actin cross-linking protein; non-muscle alpha-actinin 1; non-muscle alpha-actinin-1
Orthologs:
Homo sapiens (human) : ACTN1 (actinin alpha 1)  HGNC  Alliance
Mus musculus (house mouse) : Actn1 (actinin, alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Actn1 (actinin alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTN1 (actinin alpha 1)
Canis lupus familiaris (dog) : ACTN1 (actinin alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actn1 (actinin alpha 1)
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Allele / Splice: Actn1_v3   Actn1_v2   Actn1_v1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06103,376,557 - 103,470,497 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06116,056,248 - 116,149,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46103,188,593 - 103,282,873 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16103,192,048 - 103,286,329NCBI
Celera697,355,796 - 97,450,012 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Actn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70907
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2018-07-10
Status: ACTIVE