Hsp90aa1 (heat shock protein 90 alpha family class A member 1) - Rat Genome Database

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Gene: Hsp90aa1 (heat shock protein 90 alpha family class A member 1) Rattus norvegicus
Analyze
Symbol: Hsp90aa1
Name: heat shock protein 90 alpha family class A member 1
RGD ID: 631409
Description: Enables several functions, including Rho GDP-dissociation inhibitor binding activity; nucleotide binding activity; and sulfonylurea receptor binding activity. Involved in several processes, including cardiac muscle cell apoptotic process; positive regulation of lamellipodium assembly; and positive regulation of protein import into nucleus. Located in several cellular components, including basolateral plasma membrane; brush border membrane; and sperm mitochondrial sheath. Part of protein-containing complex. Biomarker of portal hypertension. Orthologous to human HSP90AA1 (heat shock protein 90 alpha family class A member 1); PARTICIPATES IN aldosterone signaling pathway; androgen signaling pathway; chaperone mediated autophagy pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: heat shock 86 kDa; heat shock protein 1, alpha; heat shock protein 86; heat shock protein 90, alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein HSP 90-alpha; HSP 86; Hsp86; Hsp90; Hspca; MGC105293
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26129,702,376 - 129,707,907 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl6129,702,383 - 129,707,268 (-)Ensembl
Rnor_6.06135,107,262 - 135,112,793 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,107,271 - 135,112,775 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,045,363 - 135,049,728 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,182,009 - 144,187,540 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,413,616 - 135,419,147 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16135,419,806 - 135,425,334 (-)NCBI
Celera6127,272,361 - 127,277,892 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-amphetamine  (ISO)
(S)-nicotine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-4,6-dinitrotoluene  (EXP)
2-deoxy-D-glucose  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (EXP)
3-phenylprop-2-enal  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxynon-2-enal  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
6-anilino-5,8-quinolinedione  (EXP)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
ADP  (ISO)
alachlor  (EXP)
albendazole  (ISO)
aldehydo-D-glucose  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
aristolochic acid  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
ATP  (ISO)
azoxystrobin  (ISO)
BAPTA  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
bortezomib  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
captan  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
cefaloridine  (EXP)
celastrol  (EXP,ISO)
chloromethylisothiazolinone  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP,ISO)
clonidine  (EXP)
clonidine (amino form)  (EXP)
clonidine (imino form)  (EXP)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (EXP)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
curcumin  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
cyfluthrin  (ISO)
D-glucose  (ISO)
Deguelin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (EXP,ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
disulfiram  (ISO)
diuron  (EXP)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
endrin  (EXP)
enzyme inhibitor  (ISO)
ethanol  (EXP,ISO)
etoposide  (EXP)
felbamate  (EXP)
fenofibrate  (ISO)
fenthion  (EXP)
fenvalerate  (EXP)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (ISO)
gabapentin  (EXP)
gallic acid  (ISO)
gedunin  (ISO)
gefitinib  (ISO)
geldanamycin  (EXP,ISO)
genistein  (EXP)
glucose  (ISO)
glyphosate  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP)
hypochlorous acid  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indoles  (EXP)
indometacin  (ISO)
iodide salt  (EXP)
iron(2+) sulfate (anhydrous)  (ISO)
iron(III) nitrilotriacetate  (EXP)
isoprenaline  (ISO)
ivermectin  (ISO)
kojic acid  (EXP)
lead diacetate  (ISO)
leflunomide  (EXP)
linalool  (ISO)
maneb  (ISO)
melatonin  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methamphetamine  (EXP)
methoxychlor  (EXP)
methylisothiazolinone  (ISO)
methylparaben  (ISO)
Mitotane  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nickel subsulfide  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
nitrogen dioxide  (ISO)
Nonidet P-40  (ISO)
ochratoxin A  (ISO)
organoselenium compound  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraoxon  (ISO)
paraquat  (ISO)
PCB138  (EXP)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phenethyl isothiocyanate  (EXP)
phenformin  (EXP)
phenobarbital  (EXP,ISO)
PhIP  (EXP)
phlorizin  (ISO)
picoxystrobin  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
poly(I:C)  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propiconazole  (ISO)
prostaglandin A1  (ISO)
protoporphyrin  (ISO)
pyrogallol  (ISO)
quercetin  (ISO)
quercitrin  (ISO)
rimonabant  (ISO)
ritonavir  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
sulpiride  (EXP)
T-2 toxin  (EXP)
tamoxifen  (EXP,ISO)
tanespimycin  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
thiopental  (ISO)
titanium dioxide  (EXP,ISO)
tributylstannane  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP,ISO)
trimellitic anhydride  (ISO)
triphenylstannane  (ISO)
Triptolide  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
zebularine  (ISO)
zinc atom  (EXP,ISO)
zinc pyrithione  (ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of innate immune response  (ISO,ISS)
axon extension  (ISO)
cardiac muscle cell apoptotic process  (IEP)
cellular response to heat  (IBA,ISO)
cellular response to virus  (ISO,ISS)
central nervous system neuron axonogenesis  (ISO)
chaperone-mediated autophagy  (NAS)
chaperone-mediated protein complex assembly  (ISO)
establishment of cell polarity  (ISO)
neuron migration  (IMP)
positive regulation of cardiac muscle contraction  (IEP)
positive regulation of cell size  (IMP)
positive regulation of cellular protein catabolic process  (ISO)
positive regulation of defense response to virus by host  (ISO,ISS)
positive regulation of interferon-beta production  (ISO,ISS)
positive regulation of lamellipodium assembly  (IMP)
positive regulation of nitric oxide biosynthetic process  (ISO,ISS)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of protein import into nucleus  (IMP)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein polymerization  (ISO)
positive regulation of tau-protein kinase activity  (ISO)
positive regulation of telomerase activity  (ISO)
protein folding  (IBA,ISO,TAS)
protein insertion into mitochondrial outer membrane  (ISO)
protein stabilization  (IBA,ISO)
regulation of apoptotic process  (ISO,ISS)
regulation of protein complex stability  (NAS)
regulation of protein localization  (ISO)
regulation of protein ubiquitination  (ISO)
response to antibiotic  (ISS)
response to cocaine  (IEP)
response to cold  (ISS)
response to estrogen  (IEP)
response to heat  (IEP,ISS)
response to salt stress  (IEP)
response to xenobiotic stimulus  (IEP)
skeletal muscle contraction  (IEP)
telomerase holoenzyme complex assembly  (ISO)
telomere maintenance via telomerase  (ISO)

References

References - curated
1. Bandyopadhyay U, etal., Mol Cell Biol. 2008 Sep;28(18):5747-63. doi: 10.1128/MCB.02070-07. Epub 2008 Jul 21.
2. Cannino G, etal., Mitochondrion. 2009 Nov;9(6):471-80. Epub 2009 Aug 22.
3. Chen MS, etal., J Biol Chem. 1996 Dec 13;271(50):32315-20.
4. Dugyala RR, etal., Toxicol Sci. 2002 Sep;69(1):183-90.
5. Forner F, etal., Biochim Biophys Acta. 2010 Jun;1804(6):1334-41. Epub 2010 Feb 25.
6. Garcia-Fuster MJ, etal., PLoS One. 2012;7(7):e42092. doi: 10.1371/journal.pone.0042092. Epub 2012 Jul 30.
7. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Gezen-Ak D, etal., J Alzheimers Dis. 2013;37(1):185-95. doi: 10.3233/JAD-130497.
9. Herskowitz JH, etal., J Proteome Res. 2010 Dec 3;9(12):6368-79. doi: 10.1021/pr100666c. Epub 2010 Oct 22.
10. Huey KA, etal., Exp Physiol. 2010 Dec;95(12):1145-55. Epub 2010 Sep 17.
11. Krzemień-Ojak Ł, etal., J Cell Biochem. 2017 Feb;118(2):420-429. doi: 10.1002/jcb.25669. Epub 2016 Oct 17.
12. Lappalainen J, etal., Cell Biochem Funct. 2010 Dec 2;28(8):644-50. doi: 10.1002/cbf.1702. Epub 2010 Oct 29.
13. Lee KH, etal., Exp Mol Med. 2010 Oct 31;42(10):703-11.
14. Lee KJ, etal., Cell Stress Chaperones. 2004 Mar;9(1):58-68.
15. Lei H, etal., Circ Res. 2004 Apr 16;94(7):902-9. Epub 2004 Mar 4.
16. Liou ST and Wang C, Arch Biochem Biophys. 2005 Mar 15;435(2):253-63.
17. Marshall KW, etal., Osteoarthritis Cartilage. 2005 Oct;13(10):861-71.
18. Maselli J, etal., Andrology. 2014 Mar;2(2):259-66. doi: 10.1111/j.2047-2927.2014.00185.x. Epub 2014 Jan 29.
19. MGD data from the GO Consortium
20. Newton AC Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E395-402. Epub 2009 Nov 24.
21. Park K, etal., Exp Mol Med. 2009 Jun 30;41(6):371-81.
22. Peng X, etal., J Biol Chem. 2005 Apr 1;280(13):13148-52. Epub 2005 Jan 25.
23. Pipeline to import KEGG annotations from KEGG into RGD
24. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
25. Pipeline to import SMPDB annotations from SMPDB into RGD
26. Pratt WB, etal., Handb Exp Pharmacol. 2006;(172):111-38.
27. Prescott J and Coetzee GA, Cancer Lett. 2006 Jan 8;231(1):12-9.
28. Quinta HR, etal., J Neurochem. 2010 Nov;115(3):716-34. doi: 10.1111/j.1471-4159.2010.06970.x. Epub 2010 Sep 28.
29. Raffaniello R, etal., Cell Physiol Biochem. 2009;24(5-6):369-78. doi: 10.1159/000257429. Epub 2009 Nov 4.
30. Ramirez V, etal., Cell Stress Chaperones. 2004 Summer;9(2):198-206.
31. Ramsey AJ, etal., Biochem J. 2009 Oct 12;423(3):411-9.
32. RGD automated data pipeline
33. RGD automated import pipeline for gene-chemical interactions
34. Sakisaka T, etal., EMBO J 2002 Nov 15;21(22):6125-35.
35. Sedlackova L, etal., Scand J Rheumatol. 2011;40(5):354-7. doi: 10.3109/03009742.2011.552522. Epub 2011 Mar 21.
36. Sidera K, etal., J Biol Chem. 2004 Oct 29;279(44):45379-88. Epub 2004 Aug 9.
37. Smith DF and Toft DO, Mol Endocrinol. 2008 Oct;22(10):2229-40. Epub 2008 May 1.
38. Soti C, etal., Eur J Biochem 2003 Jun;270(11):2421-8.
39. Takahashi K, etal., Osteoarthritis Cartilage. 1997 Sep;5(5):321-9.
40. Tominaga M, etal., J Gastroenterol Hepatol. 2009 Jun;24(6):1136-41. Epub 2009 Mar 11.
41. Tortosa E, etal., J Alzheimers Dis. 2009;17(2):319-25. doi: 10.3233/JAD-2009-1049.
42. Wang Y, etal., Biol Reprod. 2004 Nov;71(5):1652-64. Epub 2004 Jun 30.
43. Xilouri M and Stefanis L, Mol Cell Neurosci. 2015 May;66(Pt A):29-36. doi: 10.1016/j.mcn.2015.01.003. Epub 2015 Feb 25.
44. Yamaguchi Y, etal., J Neurosci Res. 2008 Mar;86(4):766-75.
45. Yan FF, etal., Mol Biol Cell. 2010 Jun 15;21(12):1945-54. Epub 2010 Apr 28.
46. Yang F, etal., J Heart Lung Transplant. 2011 Aug;30(8):928-34. Epub 2011 May 28.
47. Yang J and Fuller PJ, Mol Cell Endocrinol. 2012 Mar 24;350(2):196-205. doi: 10.1016/j.mce.2011.07.001. Epub 2011 Jul 18.
Additional References at PubMed
PMID:8289821   PMID:9122205   PMID:9488468   PMID:9660753   PMID:10197982   PMID:10409742   PMID:10791971   PMID:11487543   PMID:11732320   PMID:12145311   PMID:12477932   PMID:12489981  
PMID:12519789   PMID:12676772   PMID:12855682   PMID:12885400   PMID:14990148   PMID:15100099   PMID:15152036   PMID:15489334   PMID:15644312   PMID:15713458   PMID:15791211   PMID:15937123  
PMID:15951401   PMID:16169070   PMID:16207813   PMID:16489110   PMID:16809764   PMID:16854843   PMID:16910874   PMID:16968702   PMID:17202141   PMID:17349580   PMID:17517623   PMID:17634366  
PMID:17908927   PMID:17923681   PMID:18006464   PMID:18056992   PMID:18078967   PMID:18087244   PMID:18292230   PMID:18320580   PMID:18726712   PMID:19199708   PMID:19268660   PMID:19308988  
PMID:19356729   PMID:19401463   PMID:19751963   PMID:19920082   PMID:19946888   PMID:20353823   PMID:20397260   PMID:20458337   PMID:20492351   PMID:20619278   PMID:20669351   PMID:21063103  
PMID:21083699   PMID:21360678   PMID:21439793   PMID:21460846   PMID:21519787   PMID:21630459   PMID:22082260   PMID:22120110   PMID:22176470   PMID:22215678   PMID:22350213   PMID:22431752  
PMID:22658674   PMID:22681889   PMID:22964853   PMID:23064900   PMID:23106098   PMID:23349634   PMID:23376485   PMID:23484111   PMID:23533145   PMID:23666904   PMID:23904609   PMID:23965991  
PMID:24096135   PMID:24286867   PMID:24301679   PMID:24337748   PMID:24338402   PMID:24625528   PMID:24742623   PMID:25036637   PMID:25287672   PMID:25649190   PMID:26085096   PMID:26316108  
PMID:27076094   PMID:27353360   PMID:27686098   PMID:27919679   PMID:27956030   PMID:28031326   PMID:28414930   PMID:29127155   PMID:29179175   PMID:29476059   PMID:30582930   PMID:31606837  
PMID:32360748   PMID:32676275   PMID:33373917  


Genomics

Comparative Map Data
Hsp90aa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26129,702,376 - 129,707,907 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl6129,702,383 - 129,707,268 (-)Ensembl
Rnor_6.06135,107,262 - 135,112,793 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,107,271 - 135,112,775 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,045,363 - 135,049,728 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,182,009 - 144,187,540 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,413,616 - 135,419,147 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16135,419,806 - 135,425,334 (-)NCBI
Celera6127,272,361 - 127,277,892 (-)NCBICelera
Cytogenetic Map6q32NCBI
HSP90AA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl14102,080,742 - 102,139,699 (-)EnsemblGRCh38hg38GRCh38
GRCh3814102,080,742 - 102,139,749 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714102,547,079 - 102,606,086 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614101,616,828 - 101,675,839 (-)NCBINCBI36hg18NCBI36
Build 3414101,617,144 - 101,623,135NCBI
Celera1482,601,564 - 82,660,582 (-)NCBI
Cytogenetic Map14q32.31NCBI
HuRef1482,725,979 - 82,785,051 (-)NCBIHuRef
CHM1_114102,484,935 - 102,543,941 (-)NCBICHM1_1
Hsp90aa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912110,657,470 - 110,662,829 (-)NCBIGRCm39mm39
GRCm39 Ensembl12110,657,039 - 110,669,162 (-)Ensembl
GRCm3812110,691,036 - 110,696,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12110,690,605 - 110,702,728 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712111,929,246 - 111,934,605 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612111,138,843 - 111,144,202 (-)NCBImm8
Celera12111,881,002 - 111,886,365 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.75NCBI
Hsp90aa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555381,469,544 - 1,475,010 (-)NCBIChiLan1.0ChiLan1.0
HSP90AA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.114102,519,033 - 102,524,639 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14102,519,699 - 102,576,723 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01482,700,881 - 82,707,020 (-)NCBIMhudiblu_PPA_v0panPan3
HSP90AA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1870,091,203 - 70,096,107 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl870,092,217 - 70,095,243 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha869,605,578 - 69,611,507 (-)NCBI
ROS_Cfam_1.0870,369,324 - 70,375,263 (-)NCBI
UMICH_Zoey_3.1870,033,441 - 70,039,369 (-)NCBI
UNSW_CanFamBas_1.0870,098,797 - 70,104,717 (-)NCBI
UU_Cfam_GSD_1.0870,498,429 - 70,504,357 (-)NCBI
Hsp90aa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086403,873,950 - 3,879,144 (+)NCBI
SpeTri2.0NW_004936835316,767 - 321,999 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSP90AA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27129,758,754 - 129,760,542 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSP90AA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12480,016,352 - 80,019,130 (-)NCBI
Vero_WHO_p1.0NW_02366605367,207,536 - 67,213,629 (-)NCBI
Hsp90aa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247342,233,932 - 2,239,687 (+)NCBI


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
2312560Pur20Proteinuria QTL 202.10.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:301
Count of miRNA genes:195
Interacting mature miRNAs:217
Transcripts:ENSRNOT00000009556
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 41 57 41 19 41 1 1 74 35 41 11 1
Low 2 7 10 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_175761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ297736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ428213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY027778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY683455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC072489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000009556   ⟹   ENSRNOP00000009556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6135,045,363 - 135,049,728 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086310   ⟹   ENSRNOP00000075715
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,702,383 - 129,707,268 (-)Ensembl
Rnor_6.0 Ensembl6135,107,271 - 135,112,775 (-)Ensembl
RefSeq Acc Id: NM_175761   ⟹   NP_786937
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26129,702,376 - 129,707,907 (-)NCBI
Rnor_6.06135,107,262 - 135,112,793 (-)NCBI
Rnor_5.06144,182,009 - 144,187,540 (-)NCBI
RGSC_v3.46135,413,616 - 135,419,147 (-)RGD
Celera6127,272,361 - 127,277,892 (-)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_786937   ⟸   NM_175761
- UniProtKB: P82995 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075715   ⟸   ENSRNOT00000086310
RefSeq Acc Id: ENSRNOP00000009556   ⟸   ENSRNOT00000009556

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694828
Promoter ID:EPDNEW_R5353
Type:multiple initiation site
Name:LOC103692716_1
Description:heat shock protein HSP 90-alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06135,112,793 - 135,112,853EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631409 AgrOrtholog
Ensembl Genes ENSRNOG00000007219 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000059714 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000009556 UniProtKB/Swiss-Prot
  ENSRNOP00000075715 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009556 UniProtKB/Swiss-Prot
  ENSRNOT00000086310 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.120.790 UniProtKB/Swiss-Prot
  3.30.565.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7105514 IMAGE-MGC_LOAD
  IMAGE:7114546 IMAGE-MGC_LOAD
InterPro HATPase_C UniProtKB/Swiss-Prot
  HATPase_C_sf UniProtKB/Swiss-Prot
  Heat_shock_protein_90_CS UniProtKB/Swiss-Prot
  HSP90_C UniProtKB/Swiss-Prot
  Hsp90_fam UniProtKB/Swiss-Prot
  Hsp90_N UniProtKB/Swiss-Prot
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot
KEGG Report rno:299331 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105293 IMAGE-MGC_LOAD
  MGC:91423 IMAGE-MGC_LOAD
NCBI Gene 299331 ENTREZGENE
PANTHER PTHR11528 UniProtKB/Swiss-Prot
Pfam HATPase_c UniProtKB/Swiss-Prot
  HSP90 UniProtKB/Swiss-Prot
PharmGKB HSP90AA1 RGD
PhenoGen Hsp90aa1 PhenoGen
PIRSF Hsp90 UniProtKB/Swiss-Prot
PRINTS HEATSHOCK90 UniProtKB/Swiss-Prot
PROSITE HSP90 UniProtKB/Swiss-Prot
SMART HATPase_c UniProtKB/Swiss-Prot
Superfamily-SCOP SSF110942 UniProtKB/Swiss-Prot
  SSF54211 UniProtKB/Swiss-Prot
  SSF55874 UniProtKB/Swiss-Prot
UniProt HS90A_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q91XW0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-29 Hsp90aa1  heat shock protein 90 alpha family class A member 1  Hsp90aa1  heat shock protein 90kDa alpha family class A member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-25 Hsp90aa1  heat shock protein 90kDa alpha family class A member 1  Hsp90aa1  heat shock protein 90, alpha (cytosolic), class A member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Hsp90aa1  heat shock protein 90, alpha (cytosolic), class A member 1  Hspca  heat shock protein 1, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-11 Hspca  heat shock protein 1, alpha  Hsp86  heat shock protein 86  Symbol and Name updated to reflect Human and Mouse nomenclature 625702 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains a C-terminal nucleotide binding site and a N-terminal geldanamycin-sensitive ATP-binding site 724444