Micos10l1 (mitochondrial contact site and cristae organizing system subunit 10 like 1) - Rat Genome Database

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Gene: Micos10l1 (mitochondrial contact site and cristae organizing system subunit 10 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Micos10l1 (Ensembl: LOC100361944)
Name: mitochondrial contact site and cristae organizing system subunit 10 like 1 (Ensembl:hypothetical protein LOC100361944)
RGD ID: 2319136
Description: Predicted to be part of MICOS complex.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hypothetical protein LOC100361944; LOC100361944; MICOS complex subunit Mic10-like
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8697,101,080 - 97,101,484 (+)NCBIGRCr8
mRatBN7.2691,365,250 - 91,365,507 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl691,365,250 - 91,365,480 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0695,558,741 - 95,559,037 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl695,558,782 - 95,559,009 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06104,996,568 - 104,996,963 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4695,082,684 - 95,082,914 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera689,826,075 - 89,826,371 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Micos10l1
1 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:32
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000042226
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hepatobiliary system musculoskeletal system nervous system renal system reproductive system
High
Medium
Low 2 1 1 1 2 1 1
Below cutoff 2 2 2 2 3 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000042226
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl691,365,250 - 91,365,480 (+)Ensembl
Rnor_6.0 Ensembl695,558,782 - 95,559,009 (+)Ensembl
RefSeq Acc Id: XM_006240216   ⟹   XP_006240278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8697,101,080 - 97,101,484 (+)NCBI
mRatBN7.2691,365,250 - 91,365,507 (+)NCBI
Rnor_6.0695,558,741 - 95,559,037 (+)NCBI
Rnor_5.06104,996,568 - 104,996,963 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_006240278 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000093184
  ENSRNOP00000093184.1
Reference Protein Sequences
RefSeq Acc Id: XP_006240278   ⟸   XM_006240216
- UniProtKB: A0A8I6AGY6 (UniProtKB/TrEMBL)
- Sequence:

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-37138 BioCyc
Ensembl Genes ENSRNOG00000029172 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042226.5 UniProtKB/TrEMBL
InterPro Mic10 UniProtKB/TrEMBL
KEGG Report rno:100361944 UniProtKB/TrEMBL
NCBI Gene 100361944 ENTREZGENE
PANTHER MICOS COMPLEX SUBUNIT MIC10 UniProtKB/TrEMBL
  PTHR21304 UniProtKB/TrEMBL
Pfam DUF543 UniProtKB/TrEMBL
PhenoGen Micos10l1 PhenoGen
RatGTEx ENSRNOG00000029172 RatGTEx
UniProt A0A8I6AGY6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Micos10l1  mitochondrial contact site and cristae organizing system subunit 10 like 1  LOC100361944  hypothetical protein LOC100361944  Symbol and Name Changed 1299863 APPROVED
2010-05-05 LOC100361944  hypothetical protein LOC100361944      Symbol and Name status set to provisional 70820 PROVISIONAL