Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dmac2l | Rat | (+)-dexrazoxane | multiple interactions | ISO | Dmac2l (Mus musculus) | 6480464 | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of DMAC2L mRNA | CTD | PMID:26873546 | Dmac2l | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Dmac2l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ATP5S mRNA | CTD | PMID:36331819 | Dmac2l | Rat | 1,2-dichloroethane | increases expression | ISO | Dmac2l (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of ATP5S mRNA | CTD | PMID:28960355 | Dmac2l | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Dmac2l (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ATP5S mRNA | CTD | PMID:22206623 | Dmac2l | Rat | 1,3-dinitrobenzene | decreases expression | EXP | | 6480464 | 3-dinitrobenzene results in decreased expression of DMAC2L mRNA | CTD | PMID:21983209 | Dmac2l | Rat | 17beta-estradiol | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of DMAC2L mRNA | CTD | PMID:17404688 | Dmac2l | Rat | 17beta-estradiol | increases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Estradiol results in increased expression of DMAC2L mRNA | CTD | PMID:21795739 | Dmac2l | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31826744 | Dmac2l | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Dmac2l (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Dmac2l | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dmac2l (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DMAC2L mRNA | CTD | PMID:21570461 | Dmac2l | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DMAC2L mRNA | CTD | PMID:33387578 | Dmac2l | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of DMAC2L mRNA | CTD | PMID:21346803 | Dmac2l | Rat | 2-methylcholine | affects expression | ISO | DMAC2L (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of DMAC2L mRNA | CTD | PMID:21179406 | Dmac2l | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Dmac2l (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of DMAC2L mRNA | CTD | PMID:26251327 | Dmac2l | Rat | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of DMAC2L mRNA | CTD | PMID:19483382 | Dmac2l | Rat | 6-propyl-2-thiouracil | affects expression | EXP | | 6480464 | Propylthiouracil affects the expression of DMAC2L mRNA | CTD | PMID:19483382 | Dmac2l | Rat | aconitine | decreases expression | EXP | | 6480464 | Aconitine results in decreased expression of DMAC2L protein | CTD | PMID:33236894 | Dmac2l | Rat | all-trans-retinoic acid | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ATP5S mRNA | CTD | PMID:33167477 | Dmac2l | Rat | amiodarone | affects expression | EXP | | 6480464 | Amiodarone affects the expression of DMAC2L mRNA | CTD | PMID:19483382 | Dmac2l | Rat | aristolochic acid A | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ATP5S mRNA | CTD | PMID:33212167 | Dmac2l | Rat | benzbromarone | affects expression | EXP | | 6480464 | Benzbromarone affects the expression of DMAC2L mRNA | CTD | PMID:19483382 | Dmac2l | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DMAC2L mRNA | CTD | PMID:30816183 more ... | Dmac2l | Rat | bisphenol A | affects splicing | ISO | Dmac2l (Mus musculus) | 6480464 | bisphenol A affects the splicing of DMAC2L mRNA | CTD | PMID:37894381 | Dmac2l | Rat | bisphenol F | decreases expression | ISO | Dmac2l (Mus musculus) | 6480464 | bisphenol F results in decreased expression of DMAC2L mRNA | CTD | PMID:38685157 | Dmac2l | Rat | carbon nanotube | increases expression | ISO | Dmac2l (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | Dmac2l | Rat | clofibrate | affects expression | EXP | | 6480464 | Clofibrate affects the expression of DMAC2L mRNA | CTD | PMID:19483382 | Dmac2l | Rat | cobalt dichloride | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of DMAC2L mRNA | CTD | PMID:19376846 | Dmac2l | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of DMAC2L mRNA | CTD | PMID:24386269 | Dmac2l | Rat | copper atom | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of DMAC2L mRNA | CTD | PMID:20971185 | Dmac2l | Rat | copper(0) | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of DMAC2L mRNA | CTD | PMID:20971185 | Dmac2l | Rat | coumestrol | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of DMAC2L mRNA | CTD | PMID:19167446 | Dmac2l | Rat | Dibutyl phosphate | affects expression | ISO | DMAC2L (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ATP5S mRNA | CTD | PMID:37042841 | Dmac2l | Rat | dicrotophos | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of DMAC2L mRNA | CTD | PMID:28302478 | Dmac2l | Rat | dorsomorphin | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Dmac2l | Rat | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of DMAC2L mRNA | CTD | PMID:19915844 | Dmac2l | Rat | doxorubicin | multiple interactions | ISO | Dmac2l (Mus musculus) | 6480464 | [Doxorubicin co-treated with Dexrazoxane] results in increased expression of DMAC2L mRNA | CTD | PMID:26873546 | Dmac2l | Rat | doxorubicin | decreases expression | ISO | Dmac2l (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of DMAC2L mRNA | CTD | PMID:26873546 | Dmac2l | Rat | doxorubicin | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of DMAC2L mRNA | CTD | PMID:29803840 | Dmac2l | Rat | entinostat | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DMAC2L mRNA | CTD | PMID:27188386 | Dmac2l | Rat | entinostat | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | entinostat results in decreased expression of DMAC2L mRNA | CTD | PMID:26272509 | Dmac2l | Rat | ethanol | affects expression | ISO | Dmac2l (Mus musculus) | 6480464 | Ethanol affects the expression of ATP5S mRNA | CTD | PMID:30319688 | Dmac2l | Rat | fenvalerate | decreases expression | EXP | | 6480464 | fenvalerate results in decreased expression of DMAC2L protein | CTD | PMID:33656234 | Dmac2l | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of DMAC2L mRNA | CTD | PMID:24136188 | Dmac2l | Rat | fluoranthene | multiple interactions | ISO | Dmac2l (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of DMAC2L mRNA | CTD | PMID:28329830 | Dmac2l | Rat | flutamide | increases expression | ISO | Dmac2l (Mus musculus) | 6480464 | Flutamide analog results in increased expression of DMAC2L mRNA and Flutamide results in increased expression of DMAC2L mRNA | CTD | PMID:17702527 | Dmac2l | Rat | formaldehyde | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of DMAC2L mRNA | CTD | PMID:23649840 | Dmac2l | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of DMAC2L mRNA | CTD | PMID:22061828 | Dmac2l | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of DMAC2L mRNA | CTD | PMID:33387578 | Dmac2l | Rat | glycidyl methacrylate | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | glycidyl methacrylate results in decreased expression of DMAC2L protein | CTD | PMID:36641056 | Dmac2l | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of DMAC2L mRNA | CTD | PMID:21396975 | Dmac2l | Rat | irinotecan | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Irinotecan analog results in decreased expression of DMAC2L mRNA | CTD | PMID:18927307 | Dmac2l | Rat | isoprenaline | multiple interactions | EXP | | 6480464 | [Isoproterenol co-treated with POSTN protein] results in decreased expression of DMAC2L mRNA | CTD | PMID:30303030 | Dmac2l | Rat | L-ethionine | affects expression | EXP | | 6480464 | Ethionine affects the expression of DMAC2L mRNA | CTD | PMID:19483382 | Dmac2l | Rat | lipopolysaccharide | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [Acetaminophen co-treated with Lipopolysaccharides] results in decreased expression of ATP5S mRNA | CTD | PMID:31059760 | Dmac2l | Rat | methylmercury chloride | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of DMAC2L mRNA | CTD | PMID:28001369 | Dmac2l | Rat | niclosamide | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Niclosamide results in decreased expression of DMAC2L mRNA | CTD | PMID:22576131 | Dmac2l | Rat | omeprazole | affects expression | EXP | | 6480464 | Omeprazole affects the expression of DMAC2L mRNA | CTD | PMID:19483382 | Dmac2l | Rat | paracetamol | increases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of DMAC2L mRNA | CTD | PMID:22230336 and PMID:25704631 | Dmac2l | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of DMAC2L mRNA | CTD | PMID:33387578 | Dmac2l | Rat | paracetamol | affects expression | ISO | Dmac2l (Mus musculus) | 6480464 | Acetaminophen affects the expression of DMAC2L mRNA | CTD | PMID:17562736 | Dmac2l | Rat | paracetamol | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [Acetaminophen co-treated with Lipopolysaccharides] results in decreased expression of ATP5S mRNA | CTD | PMID:31059760 | Dmac2l | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Dmac2l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ATP5S mRNA | CTD | PMID:36331819 | Dmac2l | Rat | perfluorooctane-1-sulfonic acid | increases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in increased expression of ATP5S mRNA | CTD | PMID:25812627 | Dmac2l | Rat | perfluorooctanoic acid | increases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of ATP5S mRNA | CTD | PMID:25812627 | Dmac2l | Rat | phenobarbital | affects expression | ISO | Dmac2l (Mus musculus) | 6480464 | Phenobarbital affects the expression of DMAC2L mRNA | CTD | PMID:19136022 | Dmac2l | Rat | pirinixic acid | affects expression | EXP | | 6480464 | pirinixic acid affects the expression of DMAC2L mRNA | CTD | PMID:19483382 | Dmac2l | Rat | pirinixic acid | increases expression | ISO | Dmac2l (Mus musculus) | 6480464 | pirinixic acid results in increased expression of DMAC2L mRNA | CTD | PMID:20813756 and PMID:23811191 | Dmac2l | Rat | pirinixic acid | affects expression | ISO | Dmac2l (Mus musculus) | 6480464 | pirinixic acid affects the expression of DMAC2L mRNA | CTD | PMID:19136022 | Dmac2l | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of DMAC2L mRNA | CTD | PMID:19162173 | Dmac2l | Rat | progesterone | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of DMAC2L mRNA | CTD | PMID:17404688 | Dmac2l | Rat | rotenone | increases expression | ISO | Dmac2l (Mus musculus) | 6480464 | Rotenone results in increased expression of DMAC2L mRNA | CTD | PMID:17702527 | Dmac2l | Rat | SB 431542 | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Dmac2l | Rat | sulforaphane | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of DMAC2L mRNA | CTD | PMID:31838189 | Dmac2l | Rat | sunitinib | increases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Sunitinib results in increased expression of DMAC2L mRNA | CTD | PMID:31533062 | Dmac2l | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of DMAC2L mRNA | CTD | PMID:31150632 | Dmac2l | Rat | thapsigargin | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of DMAC2L mRNA | CTD | PMID:22378314 | Dmac2l | Rat | theophylline | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Theophylline results in decreased expression of DMAC2L mRNA | CTD | PMID:18951874 | Dmac2l | Rat | thioacetamide | affects expression | EXP | | 6480464 | Thioacetamide affects the expression of DMAC2L mRNA | CTD | PMID:19483382 | Dmac2l | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of DMAC2L mRNA | CTD | PMID:23411599 | Dmac2l | Rat | titanium dioxide | decreases expression | ISO | Dmac2l (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of ATP5S mRNA | CTD | PMID:29264374 | Dmac2l | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of DMAC2L mRNA | CTD | PMID:33387578 | Dmac2l | Rat | trichostatin A | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of DMAC2L mRNA | CTD | PMID:24935251 | Dmac2l | Rat | triphenyl phosphate | affects expression | ISO | DMAC2L (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ATP5S mRNA | CTD | PMID:37042841 | Dmac2l | Rat | tunicamycin | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of DMAC2L mRNA | CTD | PMID:22378314 | Dmac2l | Rat | valproic acid | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DMAC2L mRNA and Valproic Acid results in decreased expression of DMAC2L protein | CTD | PMID:24383497 more ... | Dmac2l | Rat | valproic acid | multiple interactions | ISO | DMAC2L (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DMAC2L mRNA | CTD | PMID:27188386 | Dmac2l | Rat | vorinostat | decreases expression | ISO | DMAC2L (Homo sapiens) | 6480464 | vorinostat results in decreased expression of DMAC2L mRNA | CTD | PMID:27188386 | |