Imported Annotations - MGI | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| dilated cardiomyopathy | ISS | RGD:1621573 | 13592920 | MouseDO | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Imported Annotations - OMIM
Gene-Chemical Interaction AnnotationsGene Ontology Annotations |
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene-Chemical Interaction AnnotationsGene Ontology AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | OMIM Disease Annotation Pipeline |
| 2. | RGD automated data pipeline |
| 3. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 4. | RGD automated import pipeline for gene-chemical interactions |
| 5. | Wei Y, etal., Cell Res. 2014 Mar;24(3):278-92. doi: 10.1038/cr.2014.12. Epub 2014 Jan 31. |
References - uncurated| PubMed | 3267207 9285590 10072763 12654265 16518401 16767105 17765677 17920186 18472334 18662995 18957414 19755138 20534447 20720539 22977234 23019124 23040477 23040478 23169531 23508100 23836911 25522312 25737630 26206133 26523946 27601327 27723719 |
Genomics
Comparative Map Data| Esrrb (Rattus norvegicus - Norway rat) |
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| ESRRB (Homo sapiens - human) |
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| Esrrb (Mus musculus - house mouse) |
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| Esrrb (Chinchilla lanigera - long-tailed chinchilla) |
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| ESRRB (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ESRRB (Canis lupus familiaris - dog) |
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| Esrrb (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ESRRB (Sus scrofa - pig) |
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| ESRRB (Chlorocebus sabaeus - African green monkey) |
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| Esrrb (Heterocephalus glaber - naked mole-rat) |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 14 | 11 | 8 | ||||||||||
| Low | 29 | 4 | 1 | 2 | 1 | 5 | 5 | 47 | 19 | 28 | 10 | 5 | |
| Below cutoff | 1 | 16 | 10 | 10 | 10 | 3 | 6 | 16 | 8 | 10 | 3 |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001008516 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_008764759 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594101 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07065114 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01045647 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01045648 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01045649 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AY383731 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473982 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000013867 ⟹ ENSRNOP00000013867 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001008516 ⟹ NP_001008516 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
ATGTCGTCCGAAGACAGGCACCTGGGCTCTAGCTGCGGCTCCTTCATCAAGACGGAGCCATCTAhide sequence |
| RefSeq Acc Id: | XM_008764759 ⟹ XP_008762981 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
CATCCCTGCCCATCTCTTGATCGGATGCCTCAGGACCACCCCACACTTTGTTCCACTTCAGCAAhide sequence |
| RefSeq Acc Id: | XM_017594101 ⟹ XP_017449590 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
ATCCCTGCCCATCTCTTGATCGGATGCCTCAGGACCACCCCACACTTTGTTCCACTTCAGCAAAhide sequence |
Protein Sequences| Protein RefSeqs | NP_001008516 | (Get FASTA) | NCBI Sequence Viewer |
| XP_008762981 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017449590 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAR89824 | (Get FASTA) | NCBI Sequence Viewer |
| EDL81605 | (Get FASTA) | NCBI Sequence Viewer | |
| P11475 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001008516 ⟸ NM_001008516 |
| - UniProtKB: | P11475 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGMALGTHANGLDSPPMFAGhide sequence |
| RefSeq Acc Id: | XP_008762981 ⟸ XM_008764759 |
| - Peptide Label: | isoform X2 |
| - Sequence: |
MDVSELCIPDPLGYHNQLLNRMSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGhide sequence |
| RefSeq Acc Id: | XP_017449590 ⟸ XM_017594101 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
MDVSELCIPDPLGYHNQLLNRMSSEDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGhide sequence |
| RefSeq Acc Id: | ENSRNOP00000013867 ⟸ ENSRNOT00000013867 |
Protein Domains
NR LBD
TranscriptomeStrain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1359557 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000010259 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000013867 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000013867 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Gene3D-CATH | 1.10.565.10 | UniProtKB/Swiss-Prot |
| 3.30.50.10 | UniProtKB/Swiss-Prot | |
| InterPro | NHR-like_dom_sf | UniProtKB/Swiss-Prot |
| Nucl_hrmn_rcpt_lig-bd | UniProtKB/Swiss-Prot | |
| Nuclear_hrmn_rcpt | UniProtKB/Swiss-Prot | |
| Oest-rel_rcp | UniProtKB/Swiss-Prot | |
| Oest_rcpt/oest-rel_rcp | UniProtKB/Swiss-Prot | |
| Znf_hrmn_rcpt | UniProtKB/Swiss-Prot | |
| Znf_NHR/GATA | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:299210 | UniProtKB/Swiss-Prot |
| NCBI Gene | 299210 | ENTREZGENE |
| Pfam | Hormone_recep | UniProtKB/Swiss-Prot |
| zf-C4 | UniProtKB/Swiss-Prot | |
| PhenoGen | Esrrb | PhenoGen |
| PIRSF | ER-like_NR | UniProtKB/Swiss-Prot |
| ERR1-2-3 | UniProtKB/Swiss-Prot | |
| PRINTS | STRDHORMONER | UniProtKB/Swiss-Prot |
| STROIDFINGER | UniProtKB/Swiss-Prot | |
| PROSITE | NR_LBD | UniProtKB/Swiss-Prot |
| NUCLEAR_REC_DBD_1 | UniProtKB/Swiss-Prot | |
| NUCLEAR_REC_DBD_2 | UniProtKB/Swiss-Prot | |
| SMART | HOLI | UniProtKB/Swiss-Prot |
| ZnF_C4 | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | SSF48508 | UniProtKB/Swiss-Prot |
| UniGene | Rn.104984 | ENTREZGENE |
| UniProt | ERR2_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
| UniProt Secondary | Q5QJB1 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2005-07-29 | Esrrb | estrogen-related receptor beta | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
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| More on Esrrb | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1359557 |
| Created: | 2005-07-29 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-03-31 |
| Status: | ACTIVE |
