Fos (Fos proto-oncogene, AP-1 transcription factor subunit) - Rat Genome Database
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Gene: Fos (Fos proto-oncogene, AP-1 transcription factor subunit) Rattus norvegicus
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Symbol: Fos
Name: Fos proto-oncogene, AP-1 transcription factor subunit
RGD ID: 2626
Description: Exhibits DNA binding activity; DNA-binding transcription factor activity; and transcription factor binding activity. Involved in several processes, including conditioned taste aversion; positive regulation of pri-miRNA transcription by RNA polymerase II; and response to steroid hormone. Localizes to membrane; neuron projection; and nucleus. Biomarker of congestive heart failure; glomerulonephritis; and hypertension. Orthologous to human FOS (Fos proto-oncogene, AP-1 transcription factor subunit); PARTICIPATES IN endothelin signaling pathway; fibroblast growth factor signaling pathway; forkhead class A signaling pathway; INTERACTS WITH (+)-pilocarpine; (+)-Tetrandrine; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: c-fos; c-fos oncogene; cellular oncogene fos; FBJ murine osteosarcoma viral (v-fos) oncogene homolog; FBJ murine osteosarcoma viral oncogene homolog; FBJ osteosarcoma oncogene; proto-oncogene c-FOS; proto-oncogene cFOS; v-fos FBJ murine osteosarcoma viral oncogene homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26105,121,170 - 105,124,036 (+)NCBI
Rnor_6.0 Ensembl6109,300,433 - 109,303,299 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06109,300,433 - 109,303,299 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06116,249,742 - 116,252,608 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46109,559,135 - 109,562,001 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16109,562,609 - 109,566,002 (+)NCBI
Celera6102,942,464 - 102,945,330 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-pilocarpine  (EXP)
(+)-Pimaric acid  (ISO)
(+)-Tetrandrine  (EXP)
(-)-anisomycin  (ISO)
(-)-citrinin  (ISO)
(-)-demecolcine  (ISO)
(-)-ephedrine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(-)-selegiline  (ISO)
(20R)-protopanaxadiol  (ISO)
(20S)-ginsenoside Rh1  (ISO)
(E)-roxithromycin  (ISO)
(R)-lipoic acid  (EXP)
(R)-noradrenaline  (EXP,ISO)
(S)-amphetamine  (EXP,ISO)
(S)-colchicine  (EXP)
(S)-nicotine  (EXP,ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2,4,5-tetrachlorobenzene  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,2-naphthoquinone  (ISO)
1,4-dichlorobenzene  (EXP)
1-(3-chlorophenyl)piperazine  (EXP,ISO)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-nitropyrene  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1D-myo-inositol 1,4,5-trisphosphate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4,6-trinitrotoluene  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (EXP,ISO)
2-acetamidofluorene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-aminopurine  (ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methyl-6-(phenylethynyl)pyridine  (EXP)
2-nitrotoluene  (EXP)
2-tert-butylhydroquinone  (EXP,ISO)
2-trans,6-trans-farnesyl diphosphate  (ISO)
22-Hydroxycholesterol  (ISO)
3',5'-cyclic AMP  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide  (EXP)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP,ISO)
3-iodobenzyl-5'-N-methylcarboxamidoadenosine  (EXP)
3-phenylprop-2-enal  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4,5,6,7-TETRABROMOBENZOTRIAZOLE  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol  (EXP,ISO)
4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide  (ISO)
4-DAMP(1+)  (ISO)
4-hydroxynon-2-enal  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
4-tert-Octylphenol  (EXP)
5,6,7-trimethoxyflavone  (ISO)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (EXP,ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-fluorouracil  (ISO)
6-Cyano-7-nitroquinoxaline-2,3-dione  (EXP)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
8-(3-chlorostyryl)caffeine  (EXP)
8-OH-DPAT  (EXP,ISO)
acebutolol  (ISO)
acephate  (EXP)
acetaldehyde  (EXP,ISO)
acetylsalicylic acid  (EXP,ISO)
acrivastine  (ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
acrylonitrile  (ISO)
actinomycin D  (EXP,ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
AH23848  (ISO)
alcohol  (EXP,ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
alfuzosin  (EXP)
all-trans-retinoic acid  (EXP,ISO)
allopurinol  (ISO)
alpha-hexachlorocyclohexane  (EXP)
alpha-naphthoflavone  (ISO)
alpha-pinene  (ISO)
aluminium atom  (ISO)
aluminium oxide  (ISO)
aluminium(0)  (ISO)
amiloride  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
ammonium hydroxide  (EXP)
amphetamine  (EXP,ISO)
anandamide  (EXP)
andrographolide  (ISO)
aniline  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antirheumatic drug  (ISO)
apigenin  (ISO)
apomorphine  (EXP)
arachidonic acid  (ISO)
arecoline  (ISO)
Aroclor 1254  (EXP,ISO)
arsane  (ISO)
arsenic acid  (EXP)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP,ISO)
asbestos  (ISO)
ATP  (EXP,ISO)
atrazine  (EXP,ISO)
atropine  (EXP,ISO)
avobenzone  (ISO)
Azaspiracid  (ISO)
azathioprine  (ISO)
azithromycin  (ISO)
baclofen  (EXP,ISO)
BAPTA  (EXP)
bathocuproine disulfonic acid  (ISO)
Bay-K-8644  (EXP,ISO)
bazedoxifene  (ISO)
beclomethasone  (ISO)
benazepril  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (ISO)
benzofurans  (ISO)
benzophenone  (ISO)
Benzoyl peroxide  (ISO)
beryllium difluoride  (ISO)
beryllium sulfate  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (EXP,ISO)
bezafibrate  (ISO)
bicalutamide  (ISO)
bilobalide  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (ISO)
bromochloroacetic acid  (EXP)
bucladesine  (ISO)
bufalin  (ISO)
bupropion  (ISO)
buta-1,3-diene  (ISO)
butan-1-ol  (EXP,ISO)
butanal  (ISO)
butylated hydroxyanisole  (ISO)
butyric acid  (EXP)
C60 fullerene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
caffeine  (ISO)
Calcimycin  (EXP,ISO)
calcitriol  (ISO)
calyculin a  (ISO)
camostat  (ISO)
candesartan  (EXP)
cannabidiol  (ISO)
cannabidiolic acid  (ISO)
capsaicin  (EXP,ISO)
capsazepine  (EXP)
captan  (ISO)
carbachol  (EXP,ISO)
carbamazepine  (EXP,ISO)
carbaryl  (ISO)
carbon nanotube  (ISO)
carnosine  (EXP)
carrageenan  (EXP)
cefaloridine  (EXP)
celecoxib  (EXP,ISO)
cerium trichloride  (ISO)
CGS-21680  (EXP)
chenodeoxycholic acid  (ISO)
chloral hydrate  (EXP)
Chloralose  (EXP)
chloroform  (ISO)
chloropicrin  (ISO)
chloroprene  (ISO)
chlorpromazine  (ISO)
chlorpropamide  (ISO)
chlorpyrifos  (EXP,ISO)
choline &