Psmc1 (proteasome 26S subunit, ATPase 1) - Rat Genome Database

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Gene: Psmc1 (proteasome 26S subunit, ATPase 1) Rattus norvegicus
Analyze
Symbol: Psmc1
Name: proteasome 26S subunit, ATPase 1
RGD ID: 621097
Description: Enables TBP-class protein binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of proteasome regulatory particle, base subcomplex. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with poor growth, spastic tetraplegia, and hearing loss. Orthologous to human PSMC1 (proteasome 26S subunit, ATPase 1); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-nitrofluorene; 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 26S protease regulatory subunit 4; 26S proteasome AAA-ATPase subunit RPT2; 26S proteasome regulatory subunit 4; P26s4; peptidase (prosome, macropain) 26S subunit, ATPase 1; protease (prosome, macropain) 26S subunit, ATPase 1; proteasome (prosome, macropain) 26S subunit, ATPase, 1; proteasome 26S subunit ATPase 1; s4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86125,122,497 - 125,134,859 (+)NCBIGRCr8
mRatBN7.26119,392,833 - 119,405,233 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6119,392,855 - 119,410,123 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6119,555,520 - 119,567,890 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06119,852,325 - 119,864,695 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06119,187,189 - 119,199,560 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06124,123,283 - 124,135,644 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6124,123,228 - 124,135,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06133,350,578 - 133,362,939 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46124,380,976 - 124,393,338 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16124,384,722 - 124,397,084 (+)NCBI
Celera6116,922,860 - 116,935,222 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-nitrofluorene  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP)
amiodarone  (EXP)
ammonium chloride  (EXP)
benzatropine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butane-2,3-dione  (ISO)
chlorpyrifos  (ISO)
clofibrate  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichlorine  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
elesclomol  (ISO)
ethanol  (ISO)
finasteride  (EXP)
flavone  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
hypochlorous acid  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
leflunomide  (EXP)
methapyrilene  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
omeprazole  (EXP)
ozone  (EXP)
patulin  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP)
phlorizin  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
Propiverine  (EXP)
pyrogallol  (ISO)
quinoline  (ISO)
selenium atom  (ISO)
sunitinib  (ISO)
thapsigargin  (EXP)
thioacetamide  (EXP)
trimellitic anhydride  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vitamin E  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Structures of the rat proteasomal ATPases: determination of highly conserved structural motifs and rules for their spacing. Makino Y, etal., Biochem Biophys Res Commun 1996 Mar 27;220(3):1049-54.
3. Multiple mammalian proteasomal ATPases, but not proteasome itself, are associated with TATA-binding protein and a novel transcriptional activator, TIP120. Makino Y, etal., Genes Cells. 1999 Sep;4(9):529-39.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9688553   PMID:15489334   PMID:16857966   PMID:17323924   PMID:19946888   PMID:20498273   PMID:21630459   PMID:22658674   PMID:22871113   PMID:23382946   PMID:24625528   PMID:30053369  
PMID:31904090   PMID:35352799  


Genomics

Comparative Map Data
Psmc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86125,122,497 - 125,134,859 (+)NCBIGRCr8
mRatBN7.26119,392,833 - 119,405,233 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6119,392,855 - 119,410,123 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6119,555,520 - 119,567,890 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06119,852,325 - 119,864,695 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06119,187,189 - 119,199,560 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06124,123,283 - 124,135,644 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6124,123,228 - 124,135,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06133,350,578 - 133,362,939 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46124,380,976 - 124,393,338 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16124,384,722 - 124,397,084 (+)NCBI
Celera6116,922,860 - 116,935,222 (+)NCBICelera
Cytogenetic Map6q32NCBI
PSMC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381490,256,553 - 90,275,429 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1490,256,527 - 90,275,429 (+)EnsemblGRCh38hg38GRCh38
GRCh371490,722,897 - 90,741,773 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361489,792,647 - 89,808,719 (+)NCBINCBI36Build 36hg18NCBI36
Build 341489,792,646 - 89,808,719NCBI
Celera1470,770,035 - 70,786,113 (+)NCBICelera
Cytogenetic Map14q32.11NCBI
HuRef1470,897,288 - 70,913,368 (+)NCBIHuRef
CHM1_11490,661,102 - 90,677,177 (+)NCBICHM1_1
T2T-CHM13v2.01484,478,491 - 84,499,697 (+)NCBIT2T-CHM13v2.0
Psmc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912100,076,461 - 100,089,623 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12100,076,413 - 100,089,664 (+)EnsemblGRCm39 Ensembl
GRCm3812100,110,202 - 100,123,364 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12100,110,154 - 100,123,405 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712101,348,412 - 101,361,574 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612100,511,252 - 100,524,414 (+)NCBIMGSCv36mm8
Celera12101,336,798 - 101,349,996 (+)NCBICelera
Cytogenetic Map12ENCBI
cM Map1250.43NCBI
Psmc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543812,704,691 - 12,721,050 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543812,705,328 - 12,721,050 (+)NCBIChiLan1.0ChiLan1.0
PSMC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21591,400,672 - 91,416,861 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11490,617,193 - 90,633,367 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01470,873,846 - 70,889,988 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11490,225,405 - 90,241,638 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1490,225,405 - 90,241,641 (+)Ensemblpanpan1.1panPan2
PSMC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1861,272,363 - 61,285,886 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl861,272,363 - 61,285,886 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha860,851,941 - 60,865,464 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0861,544,550 - 61,558,080 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl861,544,577 - 61,558,051 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1861,225,967 - 61,239,658 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0861,274,899 - 61,288,618 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0861,603,196 - 61,616,721 (+)NCBIUU_Cfam_GSD_1.0
Psmc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864014,600,035 - 14,613,399 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648817,455,461 - 17,469,527 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648817,455,612 - 17,468,933 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7112,027,921 - 112,041,489 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17112,027,904 - 112,041,360 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27118,594,314 - 118,607,772 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PSMC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12467,979,449 - 67,995,103 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605355,265,330 - 55,281,008 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psmc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473412,153,919 - 12,174,650 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Psmc1
67 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:214
Count of miRNA genes:143
Interacting mature miRNAs:162
Transcripts:ENSRNOT00000005329
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat

Markers in Region
BE107583  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26119,403,531 - 119,403,747 (+)MAPPERmRatBN7.2
Rnor_6.06124,133,944 - 124,134,159NCBIRnor6.0
Rnor_5.06133,361,239 - 133,361,454UniSTSRnor5.0
RGSC_v3.46124,391,637 - 124,391,852UniSTSRGSC3.4
Celera6116,933,521 - 116,933,736UniSTS
RH 3.4 Map6856.9UniSTS
Cytogenetic Map6q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000005329   ⟹   ENSRNOP00000005329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6119,392,855 - 119,405,233 (+)Ensembl
Rnor_6.0 Ensembl6124,123,228 - 124,135,658 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113995   ⟹   ENSRNOP00000095712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6119,393,070 - 119,410,123 (+)Ensembl
RefSeq Acc Id: NM_057123   ⟹   NP_476464
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86125,122,497 - 125,134,859 (+)NCBI
mRatBN7.26119,392,869 - 119,405,233 (+)NCBI
Rnor_6.06124,123,283 - 124,135,644 (+)NCBI
Rnor_5.06133,350,578 - 133,362,939 (+)NCBI
RGSC_v3.46124,380,976 - 124,393,338 (+)RGD
Celera6116,922,860 - 116,935,222 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_476464 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH63157 (Get FASTA)   NCBI Sequence Viewer  
  BAA09341 (Get FASTA)   NCBI Sequence Viewer  
  EDL81712 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005329
  ENSRNOP00000005329.5
  ENSRNOP00000095712.1
  ENSRNOP00055020933
  ENSRNOP00060005148
  ENSRNOP00065018534
GenBank Protein P62193 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_476464   ⟸   NM_057123
- UniProtKB: P62193 (UniProtKB/Swiss-Prot),   A6JEG8 (UniProtKB/TrEMBL),   A0A8I6APJ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005329   ⟸   ENSRNOT00000005329
RefSeq Acc Id: ENSRNOP00000095712   ⟸   ENSRNOT00000113995
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62193-F1-model_v2 AlphaFold P62193 1-440 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694774
Promoter ID:EPDNEW_R5298
Type:initiation region
Name:Psmc1_1
Description:proteasome 26S subunit, ATPase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06124,123,276 - 124,123,336EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621097 AgrOrtholog
BioCyc Gene G2FUF-36501 BioCyc
Ensembl Genes ENSRNOG00000003951 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055014985 UniProtKB/Swiss-Prot
  ENSRNOG00060004068 UniProtKB/Swiss-Prot
  ENSRNOG00065014401 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005329 ENTREZGENE
  ENSRNOT00000005329.7 UniProtKB/TrEMBL
  ENSRNOT00000113995.1 UniProtKB/TrEMBL
  ENSRNOT00055025665 UniProtKB/Swiss-Prot
  ENSRNOT00060006845 UniProtKB/Swiss-Prot
  ENSRNOT00065023815 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.8.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6919865 IMAGE-MGC_LOAD
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_ATP_ID_OB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117263 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72724 IMAGE-MGC_LOAD
NCBI Gene 117263 ENTREZGENE
PANTHER 26S PROTEASOME REGULATORY SUBUNIT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  26S PROTEASOME REGULATORY SUBUNIT 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_ATP_ID_OB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PSMC1 RGD
PhenoGen Psmc1 PhenoGen
PROSITE AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003951 RatGTEx
  ENSRNOG00055014985 RatGTEx
  ENSRNOG00060004068 RatGTEx
  ENSRNOG00065014401 RatGTEx
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6APJ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UHV1_RAT UniProtKB/TrEMBL
  A6JEG8 ENTREZGENE, UniProtKB/TrEMBL
  P62193 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P49014 UniProtKB/Swiss-Prot
  Q03527 UniProtKB/Swiss-Prot
  Q96AZ3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-19 Psmc1  proteasome 26S subunit, ATPase 1  Psmc1  proteasome (prosome, macropain) 26S subunit, ATPase, 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Psmc1  proteasome (prosome, macropain) 26S subunit, ATPase, 1  Psmc1  protease (prosome, macropain) 26S subunit, ATPase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Psmc1  protease (prosome, macropain) 26S subunit, ATPase 1  Psmc1  peptidase (prosome, macropain) 26S subunit, ATPase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Psmc1  peptidase (prosome, macropain) 26S subunit, ATPase 1    protease (prosome, macropain) 26S subunit, ATPase 1  Name updated 1299863 APPROVED
2002-08-07 Psmc1  protease (prosome, macropain) 26S subunit, ATPase 1      Symbol and Name status set to provisional 70820 PROVISIONAL