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Gene: Alkbh1 (alkB homolog 1, histone H2A dioxygenase) Rattus norvegicus
Symbol: Alkbh1
Name: alkB homolog 1, histone H2A dioxygenase
Description: Predicted to have several functions, including class I DNA-(apurinic or apyrimidinic site) endonuclease activity; demethylase activity; and ferrous iron binding activity. Predicted to be involved in several processes, including generation of neurons; nucleic acid metabolic process; and regulation of translation. Predicted to localize to the endoplasmic reticulum; mitochondrion; and nuclear lumen. Orthologous to human ALKBH1 (alkB homolog 1, histone H2A dioxygenase); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: alkB, alkylation repair homolog; alkB, alkylation repair homolog (E. coli); alkB, alkylation repair homolog 1; alkB, alkylation repair homolog 1 (E. coli); Alkbh; alkylated DNA repair protein alkB homolog 1; DNA demethylase ALKBH1; LOC362766
Homo sapiens (human) : ALKBH1 (alkB homolog 1, histone H2A dioxygenase)  HGNC  Alliance
Mus musculus (house mouse) : Alkbh1 (alkB homolog 1, histone H2A dioxygenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alkbh1 (alkB homolog 1, histone H2A dioxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALKBH1 (alkB homolog 1, histone H2A dioxygenase)
Canis lupus familiaris (dog) : ALKBH1 (alkB homolog 1, histone H2A dioxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alkbh1 (alkB homolog 1, histone H2A dioxygenase)
Sus scrofa (pig) : ALKBH1 (alkB homolog 1, histone H2A dioxygenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06111,456,096 - 111,476,829 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,456,187 - 111,477,090 (-)Ensembl
Rnor_5.06120,737,001 - 120,757,497 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46111,662,506 - 111,682,061 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16111,667,836 - 111,685,567 (-)NCBI
Celera6104,888,877 - 104,908,497 (-)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Alkbh1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308327
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.