Acot4 (acyl-CoA thioesterase 4) - Rat Genome Database

Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Acot4 (acyl-CoA thioesterase 4) Rattus norvegicus
Analyze
Symbol: Acot4
Name: acyl-CoA thioesterase 4
RGD ID: 1596753
Description: Predicted to enable acyl-CoA hydrolase activity and succinyl-CoA hydrolase activity. Predicted to be involved in carboxylic acid metabolic process and succinyl-CoA metabolic process. Predicted to be active in peroxisome. Orthologous to human ACOT4 (acyl-CoA thioesterase 4); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acyl-coenzyme A thioesterase 4; LOC681337; similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26103,668,699 - 103,674,037 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,668,753 - 103,673,917 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6103,830,503 - 103,835,783 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,129,719 - 104,134,999 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,499,170 - 103,504,450 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,517,668 - 107,522,952 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,517,668 - 107,522,952 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06118,021,264 - 118,026,536 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,075,508 - 108,080,792 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6101,498,707 - 101,503,970 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
amiodarone  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
azoxystrobin  (EXP)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bromobenzene  (EXP)
butanal  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
ciprofibrate  (EXP,ISO)
clofibrate  (EXP,ISO)
coumarin  (EXP)
coumestrol  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
dichloroacetic acid  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenofibrate  (EXP)
fenthion  (ISO)
furan  (EXP)
gemfibrozil  (EXP)
genistein  (ISO)
glafenine  (EXP)
glutaryl-CoA  (ISO)
glyphosate  (EXP)
GW 4064  (ISO)
GW 7647  (ISO)
imidacloprid  (EXP)
indole-3-methanol  (EXP)
indometacin  (EXP)
L-ethionine  (EXP)
leflunomide  (EXP)
methotrexate  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
oleic acid  (ISO)
omeprazole  (EXP)
paracetamol  (EXP,ISO)
parathion  (ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
senecionine  (ISO)
succinyl-CoA  (ISO)
sulforaphane  (ISO)
tetrachloroethene  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (EXP)
trovafloxacin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
zaragozic acid A  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
peroxisome  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14561759   PMID:16141203   PMID:16940157   PMID:20178365  


Genomics

Comparative Map Data
Acot4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26103,668,699 - 103,674,037 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6103,668,753 - 103,673,917 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6103,830,503 - 103,835,783 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,129,719 - 104,134,999 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,499,170 - 103,504,450 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06107,517,668 - 107,522,952 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6107,517,668 - 107,522,952 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06118,021,264 - 118,026,536 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,075,508 - 108,080,792 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6101,498,707 - 101,503,970 (+)NCBICelera
Cytogenetic Map6q31NCBI
ACOT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381473,591,873 - 73,595,766 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1473,591,873 - 73,595,766 (+)EnsemblGRCh38hg38GRCh38
GRCh371474,058,577 - 74,062,470 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,128,163 - 73,132,223 (+)NCBINCBI36Build 36hg18NCBI36
Celera1454,094,503 - 54,098,556 (+)NCBICelera
Cytogenetic Map14q24.3NCBI
HuRef1454,226,329 - 54,230,382 (+)NCBIHuRef
CHM1_11473,998,002 - 74,002,055 (+)NCBICHM1_1
T2T-CHM13v2.01467,799,383 - 67,803,276 (+)NCBIT2T-CHM13v2.0
Acot4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,084,028 - 84,091,497 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,085,153 - 84,095,375 (+)EnsemblGRCm39 Ensembl
GRCm381284,037,254 - 84,044,723 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,038,379 - 84,048,601 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,379,329 - 85,385,673 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361284,928,127 - 84,934,471 (+)NCBIMGSCv36mm8
Celera1285,484,852 - 85,491,186 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.01NCBI
ACOT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11473,895,275 - 73,907,168 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01454,150,843 - 54,155,119 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11473,008,597 - 73,012,673 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1473,008,909 - 73,012,561 (+)Ensemblpanpan1.1panPan2
ACOT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1846,889,326 - 46,894,379 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl846,852,880 - 46,911,640 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha846,573,784 - 46,580,670 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0847,118,497 - 47,125,383 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1846,786,164 - 46,791,040 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0846,804,351 - 46,811,227 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0847,194,704 - 47,201,587 (+)NCBIUU_Cfam_GSD_1.0
Acot4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864029,152,711 - 29,157,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364882,912,016 - 2,914,995 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049364882,912,016 - 2,914,995 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100158115
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl796,868,157 - 96,949,358 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1796,941,065 - 96,945,834 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,787,631 - 102,791,737 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACOT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12450,806,736 - 50,811,294 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2450,807,212 - 50,811,181 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605338,972,271 - 38,996,921 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Acot4
43 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:101
Count of miRNA genes:81
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000013753
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat

Markers in Region
RH141676  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26103,672,839 - 103,673,022 (+)MAPPERmRatBN7.2
Rnor_6.06107,521,755 - 107,521,937NCBIRnor6.0
Rnor_5.06118,022,267 - 118,022,449UniSTSRnor5.0
RGSC_v3.46108,079,595 - 108,079,777UniSTSRGSC3.4
Celera6101,502,794 - 101,502,976UniSTS
RH 3.4 Map6732.89UniSTS
Cytogenetic Map6q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 12 12 12 15
Low 2 8 45 29 18 29 5 6 48 16 21 10 5
Below cutoff 1 27 3 4 24 4 20 1 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013753   ⟹   ENSRNOP00000013754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6103,668,753 - 103,673,917 (+)Ensembl
Rnor_6.0 Ensembl6107,517,668 - 107,522,952 (+)Ensembl
RefSeq Acc Id: NM_001109440   ⟹   NP_001102910
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26103,668,753 - 103,674,037 (+)NCBI
Rnor_6.06107,517,668 - 107,522,952 (+)NCBI
Rnor_5.06118,021,264 - 118,026,536 (-)NCBI
RGSC_v3.46108,075,508 - 108,080,792 (+)RGD
Celera6101,498,707 - 101,503,970 (+)RGD
Sequence:
RefSeq Acc Id: XM_039112919   ⟹   XP_038968847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26103,668,699 - 103,672,444 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102910 (Get FASTA)   NCBI Sequence Viewer  
  XP_038968847 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL81471 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001102910   ⟸   NM_001109440
- UniProtKB: D3ZIQ1 (UniProtKB/TrEMBL),   A6JDS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013754   ⟸   ENSRNOT00000013753
RefSeq Acc Id: XP_038968847   ⟸   XM_039112919
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIQ1-F1-model_v2 AlphaFold D3ZIQ1 1-421 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596753 AgrOrtholog
BioCyc Gene G2FUF-36844 BioCyc
BioCyc Pathway PWY-5148 [acyl-CoA hydrolysis] BioCyc
  PWY-5972 [stearate biosynthesis I (animals)] BioCyc
  PWY-5996 [oleate biosynthesis II (animals and fungi)] BioCyc
  PWY-8042 [acylceramide biosynthesis] BioCyc
  PWY3O-1801 [palmitoleate biosynthesis IV (fungi and animals)] BioCyc
Ensembl Genes ENSRNOG00000046864 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000013754 ENTREZGENE
  ENSRNOP00000013754.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013753 ENTREZGENE
  ENSRNOT00000013753.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2240 UniProtKB/TrEMBL
  3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  Acyl-CoA_thioEstase_long-chain UniProtKB/TrEMBL
  BAAT_C UniProtKB/TrEMBL
  Thio_Ohase/aa_AcTrfase UniProtKB/TrEMBL
  Thio_Ohase/BAAT_N UniProtKB/TrEMBL
KEGG Report rno:681337 UniProtKB/TrEMBL
NCBI Gene 681337 ENTREZGENE
PANTHER ACYL-COENZYME A THIOESTERASE-RELATED UniProtKB/TrEMBL
  PEROXISOMAL SUCCINYL-COENZYME A THIOESTERASE UniProtKB/TrEMBL
Pfam BAAT_C UniProtKB/TrEMBL
  Bile_Hydr_Trans UniProtKB/TrEMBL
PhenoGen Acot4 PhenoGen
PIRSF Acyl-CoA_hydro UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A6JDS7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIQ1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Acot4  acyl-CoA thioesterase 4  LOC681337  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC681337  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)  LOC679253  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)  Data Merged 1643240 APPROVED
2006-11-20 LOC681337  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC679253  similar to Acyl-CoA thioesterase 4 (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-coA thioesterase Ib) (PTE-Ib) (PTE-2b)      Symbol and Name status set to provisional 70820 PROVISIONAL