Ppp2r5c (protein phosphatase 2, regulatory subunit B', gamma) - Rat Genome Database

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Gene: Ppp2r5c (protein phosphatase 2, regulatory subunit B', gamma) Rattus norvegicus
Analyze
Symbol: Ppp2r5c
Name: protein phosphatase 2, regulatory subunit B', gamma
RGD ID: 1585097
Description: Predicted to enable peptidase activity and protein phosphatase activator activity. Predicted to be involved in negative regulation of cell population proliferation; protein dephosphorylation; and signal transduction by p53 class mediator. Predicted to act upstream of or within proteasome-mediated ubiquitin-dependent protein catabolic process and protein processing. Predicted to be located in several cellular components, including Golgi apparatus; chromosome, centromeric region; and nucleoplasm. Predicted to be part of protein phosphatase type 2A complex. Predicted to be active in cytosol and nucleus. Orthologous to human PPP2R5C (protein phosphatase 2 regulatory subunit B'gamma); PARTICIPATES IN mRNA decay pathway; Wnt signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; amitrole; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC500722; LOC691318; protein phosphatase 2, regulatory subunit B (B56), gamma isoform; protein phosphatase 2, regulatory subunit B' gamma isoform; protein phosphatase 2, regulatory subunit B', gamma isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform; similar to protein phosphatase 2A B56 regulatory subunit gamma 3 isoform; similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B su...
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86135,282,947 - 135,419,591 (+)NCBIGRCr8
mRatBN7.26129,461,689 - 129,598,344 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6129,461,648 - 129,598,346 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6129,681,007 - 129,772,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06129,977,002 - 130,068,841 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06129,340,729 - 129,432,704 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06134,804,128 - 134,941,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6134,804,141 - 134,939,358 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06143,942,657 - 144,077,935 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,204,405 - 135,299,068 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6127,073,782 - 127,165,461 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-vinylcyclohexene dioxide  (ISO)
6-propyl-2-thiouracil  (EXP)
alpha-phellandrene  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
camptothecin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
coenzyme Q10  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
decabromodiphenyl ether  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
dicrotophos  (ISO)
dimercaprol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenthion  (ISO)
finasteride  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
inulin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
mitomycin C  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
propiconazole  (EXP)
rac-lactic acid  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP)
sodium fluoride  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
tetrachloromethane  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8703017   PMID:12297508   PMID:16580887   PMID:16603688   PMID:16717086   PMID:17174897   PMID:17245430   PMID:17416611   PMID:19131648  


Genomics

Comparative Map Data
Ppp2r5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86135,282,947 - 135,419,591 (+)NCBIGRCr8
mRatBN7.26129,461,689 - 129,598,344 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6129,461,648 - 129,598,346 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6129,681,007 - 129,772,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06129,977,002 - 130,068,841 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06129,340,729 - 129,432,704 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06134,804,128 - 134,941,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6134,804,141 - 134,939,358 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06143,942,657 - 144,077,935 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,204,405 - 135,299,068 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6127,073,782 - 127,165,461 (+)NCBICelera
Cytogenetic Map6q32NCBI
PPP2R5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814101,760,573 - 101,927,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14101,761,709 - 101,927,989 (+)EnsemblGRCh38hg38GRCh38
GRCh3714102,226,910 - 102,394,329 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614101,345,925 - 101,463,831 (+)NCBINCBI36Build 36hg18NCBI36
Build 3414101,345,924 - 101,442,736NCBI
Celera1482,282,956 - 82,448,834 (+)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1482,408,998 - 82,573,806 (+)NCBIHuRef
CHM1_114102,166,309 - 102,332,185 (+)NCBICHM1_1
T2T-CHM13v2.01495,996,275 - 96,163,606 (+)NCBIT2T-CHM13v2.0
Ppp2r5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912110,413,532 - 110,549,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12110,413,554 - 110,549,496 (+)EnsemblGRCm39 Ensembl
GRCm3812110,447,144 - 110,583,075 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12110,447,120 - 110,583,062 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712111,685,389 - 111,821,271 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612110,933,696 - 111,028,359 (+)NCBIMGSCv36mm8
Celera12111,641,643 - 111,773,413 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.56NCBI
Ppp2r5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555381,276,083 - 1,361,639 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555381,233,511 - 1,363,956 (+)NCBIChiLan1.0ChiLan1.0
PPP2R5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215102,915,190 - 103,081,747 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114102,131,645 - 102,298,187 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01482,383,086 - 82,549,822 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114102,206,546 - 102,372,978 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14102,206,396 - 102,372,978 (+)Ensemblpanpan1.1panPan2
PPP2R5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1869,846,311 - 69,969,409 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl869,846,446 - 69,967,578 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha869,361,349 - 69,484,545 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0870,124,041 - 70,247,431 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl870,123,944 - 70,247,431 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1869,788,763 - 69,911,878 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0869,854,037 - 69,977,442 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0870,253,916 - 70,377,552 (+)NCBIUU_Cfam_GSD_1.0
Ppp2r5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086404,003,425 - 4,141,415 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493683596,930 - 192,756 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493683554,478 - 192,486 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP2R5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27129,864,473 - 129,957,091 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP2R5C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12479,703,316 - 79,875,379 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2479,703,312 - 79,875,389 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605366,888,098 - 67,054,272 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp2r5c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247342,335,243 - 2,470,811 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247342,337,649 - 2,471,319 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ppp2r5c
679 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:33
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000007595
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat

Markers in Region
BE105886  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26129,526,511 - 129,526,667 (+)MAPPERmRatBN7.2
Rnor_6.06134,868,302 - 134,868,457NCBIRnor6.0
Rnor_5.06144,006,164 - 144,006,319UniSTSRnor5.0
RGSC_v3.46135,229,276 - 135,229,431UniSTSRGSC3.4
Celera6127,097,454 - 127,097,609UniSTS
RH 3.4 Map6785.99UniSTS
Cytogenetic Map6q32UniSTS
BI294771  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26129,496,897 - 129,497,061 (+)MAPPERmRatBN7.2
Rnor_6.06134,838,688 - 134,838,851NCBIRnor6.0
Rnor_5.06143,976,550 - 143,976,713UniSTSRnor5.0
RGSC_v3.46135,198,420 - 135,198,583UniSTSRGSC3.4
Celera6127,067,693 - 127,067,856UniSTS
RH 3.4 Map6786.7UniSTS
Cytogenetic Map6q32UniSTS
BE107627  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26129,460,245 - 129,460,454 (+)MAPPERmRatBN7.2
Rnor_6.06134,802,507 - 134,802,715NCBIRnor6.0
Rnor_5.06143,940,470 - 143,940,678UniSTSRnor5.0
RGSC_v3.46135,161,860 - 135,162,068UniSTSRGSC3.4
Celera6127,031,033 - 127,031,241UniSTS
RH 3.4 Map6787.1UniSTS
Cytogenetic Map6q32UniSTS
RH141468  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26129,547,050 - 129,547,261 (+)MAPPERmRatBN7.2
Rnor_6.06134,888,826 - 134,889,036NCBIRnor6.0
Rnor_5.06144,026,474 - 144,026,684UniSTSRnor5.0
RGSC_v3.46135,249,835 - 135,250,045UniSTSRGSC3.4
Celera6127,117,860 - 127,118,070UniSTS
RH 3.4 Map6786.5UniSTS
Cytogenetic Map6q32UniSTS
AA849549  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26129,597,965 - 129,598,185 (+)MAPPERmRatBN7.2
Rnor_6.06134,941,534 - 134,941,753NCBIRnor6.0
Rnor_5.06144,077,557 - 144,077,776UniSTSRnor5.0
RGSC_v3.46135,300,852 - 135,301,071UniSTSRGSC3.4
Celera6127,167,637 - 127,167,856UniSTS
RH 3.4 Map6786.59UniSTS
Cytogenetic Map6q32UniSTS
AA801126  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26129,493,130 - 129,493,299 (+)MAPPERmRatBN7.2
Rnor_6.06134,834,923 - 134,835,091NCBIRnor6.0
Rnor_5.06143,972,785 - 143,972,953UniSTSRnor5.0
RGSC_v3.46135,194,655 - 135,194,823UniSTSRGSC3.4
Celera6127,063,928 - 127,064,096UniSTS
RH 3.4 Map6783.51UniSTS
Cytogenetic Map6q32UniSTS
Ppp2r5c  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26129,560,682 - 129,562,176 (+)MAPPERmRatBN7.2
Rnor_6.06134,903,948 - 134,905,441NCBIRnor6.0
Rnor_5.06144,039,660 - 144,041,153UniSTSRnor5.0
RGSC_v3.46135,263,291 - 135,264,784UniSTSRGSC3.4
Cytogenetic Map6q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001415128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide FQ224308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000007595   ⟹   ENSRNOP00000007595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,502,879 - 129,598,094 (+)Ensembl
Rnor_6.0 Ensembl6134,844,676 - 134,939,358 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086143   ⟹   ENSRNOP00000071002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,461,648 - 129,590,305 (+)Ensembl
Rnor_6.0 Ensembl6134,804,141 - 134,937,032 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095073   ⟹   ENSRNOP00000089250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,461,648 - 129,598,346 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103295   ⟹   ENSRNOP00000079611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,461,861 - 129,597,687 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104738   ⟹   ENSRNOP00000080856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,461,861 - 129,597,687 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105165   ⟹   ENSRNOP00000097048
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,461,648 - 129,464,263 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106937   ⟹   ENSRNOP00000090474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,502,879 - 129,598,335 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113176   ⟹   ENSRNOP00000085964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6129,502,815 - 129,598,346 (+)Ensembl
RefSeq Acc Id: NM_001191112   ⟹   NP_001178041
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,324,096 - 135,419,591 (+)NCBI
mRatBN7.26129,502,837 - 129,598,344 (+)NCBI
Rnor_6.06134,844,659 - 134,939,358 (+)NCBI
Rnor_5.06143,942,657 - 144,077,935 (+)NCBI
Celera6127,073,782 - 127,165,461 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001415125   ⟹   NP_001402054
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,283,034 - 135,419,591 (+)NCBI
mRatBN7.26129,461,769 - 129,598,344 (+)NCBI
RefSeq Acc Id: NM_001415126   ⟹   NP_001402055
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,283,034 - 135,419,591 (+)NCBI
mRatBN7.26129,461,769 - 129,598,344 (+)NCBI
RefSeq Acc Id: NM_001415127   ⟹   NP_001402056
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,283,034 - 135,419,591 (+)NCBI
mRatBN7.26129,461,769 - 129,598,344 (+)NCBI
RefSeq Acc Id: NM_001415128   ⟹   NP_001402057
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,324,096 - 135,419,591 (+)NCBI
mRatBN7.26129,502,837 - 129,598,344 (+)NCBI
RefSeq Acc Id: XM_008764962   ⟹   XP_008763184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,282,949 - 135,407,787 (+)NCBI
mRatBN7.26129,461,692 - 129,586,546 (+)NCBI
Rnor_6.06134,804,128 - 134,930,110 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039112971   ⟹   XP_038968899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,282,949 - 135,417,041 (+)NCBI
mRatBN7.26129,461,689 - 129,595,795 (+)NCBI
RefSeq Acc Id: XM_039112973   ⟹   XP_038968901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,324,072 - 135,419,591 (+)NCBI
mRatBN7.26129,502,811 - 129,598,344 (+)NCBI
RefSeq Acc Id: XM_039112974   ⟹   XP_038968902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,324,072 - 135,417,012 (+)NCBI
mRatBN7.26129,502,812 - 129,595,765 (+)NCBI
RefSeq Acc Id: XM_063262522   ⟹   XP_063118592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,282,947 - 135,419,591 (+)NCBI
RefSeq Acc Id: XM_063262523   ⟹   XP_063118593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,350,042 - 135,419,591 (+)NCBI
RefSeq Acc Id: XM_063262524   ⟹   XP_063118594
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,324,072 - 135,417,041 (+)NCBI
RefSeq Acc Id: XM_063262525   ⟹   XP_063118595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,324,072 - 135,407,787 (+)NCBI
RefSeq Acc Id: XM_063262527   ⟹   XP_063118597
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86135,283,167 - 135,419,591 (+)NCBI
RefSeq Acc Id: NP_001178041   ⟸   NM_001191112
- Peptide Label: isoform 4
- UniProtKB: D4A1A5 (UniProtKB/TrEMBL),   A0A8I6AAX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763184   ⟸   XM_008764962
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JZD1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000007595   ⟸   ENSRNOT00000007595
Ensembl Acc Id: ENSRNOP00000071002   ⟸   ENSRNOT00000086143
RefSeq Acc Id: XP_038968899   ⟸   XM_039112971
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZRC2 (UniProtKB/TrEMBL),   A0A0G2JZD1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968901   ⟸   XM_039112973
- Peptide Label: isoform X7
- UniProtKB: A0A8I6AAX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968902   ⟸   XM_039112974
- Peptide Label: isoform X8
- UniProtKB: A0A0G2JZD1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000079611   ⟸   ENSRNOT00000103295
Ensembl Acc Id: ENSRNOP00000080856   ⟸   ENSRNOT00000104738
Ensembl Acc Id: ENSRNOP00000097048   ⟸   ENSRNOT00000105165
Ensembl Acc Id: ENSRNOP00000089250   ⟸   ENSRNOT00000095073
Ensembl Acc Id: ENSRNOP00000090474   ⟸   ENSRNOT00000106937
Ensembl Acc Id: ENSRNOP00000085964   ⟸   ENSRNOT00000113176
RefSeq Acc Id: NP_001402055   ⟸   NM_001415126
- Peptide Label: isoform 2
- UniProtKB: A0A8I5ZRT0 (UniProtKB/TrEMBL),   A0A0G2JZD1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402054   ⟸   NM_001415125
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JZD1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402056   ⟸   NM_001415127
- Peptide Label: isoform 3
- UniProtKB: A0A8I6AKJ3 (UniProtKB/TrEMBL),   A0A0G2JZD1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001402057   ⟸   NM_001415128
- Peptide Label: isoform 5
- UniProtKB: A0A8I6A0C3 (UniProtKB/TrEMBL),   A0A8I6AAX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118592   ⟸   XM_063262522
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JZD1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118597   ⟸   XM_063262527
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AAX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118594   ⟸   XM_063262524
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JZD1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118595   ⟸   XM_063262525
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AAX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118593   ⟸   XM_063262523
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AAX1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JZD1-F1-model_v2 AlphaFold A0A0G2JZD1 1-550 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694831
Promoter ID:EPDNEW_R5350
Type:initiation region
Name:Ppp2r5c_2
Description:protein phosphatase 2, regulatory subunit B', gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R5351  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06134,804,134 - 134,804,194EPDNEW
RGD ID:13694826
Promoter ID:EPDNEW_R5351
Type:initiation region
Name:Ppp2r5c_1
Description:protein phosphatase 2, regulatory subunit B', gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R5350  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06134,844,627 - 134,844,687EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1585097 AgrOrtholog
BioCyc Gene G2FUF-35889 BioCyc
Ensembl Genes ENSRNOG00000004973 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007595.8 UniProtKB/TrEMBL
  ENSRNOT00000086143.2 UniProtKB/TrEMBL
  ENSRNOT00000095073.1 UniProtKB/TrEMBL
  ENSRNOT00000103295.1 UniProtKB/TrEMBL
  ENSRNOT00000104738.1 UniProtKB/TrEMBL
  ENSRNOT00000105165.1 UniProtKB/TrEMBL
  ENSRNOT00000106937.1 UniProtKB/TrEMBL
  ENSRNOT00000113176.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  PP2A_B56 UniProtKB/TrEMBL
KEGG Report rno:691318 UniProtKB/TrEMBL
NCBI Gene 691318 ENTREZGENE
PANTHER B56 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM UniProtKB/TrEMBL
Pfam B56 UniProtKB/TrEMBL
PhenoGen Ppp2r5c PhenoGen
PIRSF PP2A_B56 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004973 RatGTEx
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A0G2JZD1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZRC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZRT0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0C3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAX1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AKJ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AR89_RAT UniProtKB/TrEMBL
  D4A1A5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Ppp2r5c  protein phosphatase 2, regulatory subunit B', gamma  LOC684586  similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B su...  Data merged from RGD:1589099 1643240 APPROVED
2011-08-02 Ppp2r5c  protein phosphatase 2, regulatory subunit B', gamma  Ppp2r5c  protein phosphatase 2, regulatory subunit B', gamma isoform  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-10-22 Ppp2r5c  protein phosphatase 2, regulatory subunit B', gamma isoform  Ppp2r5c  protein phosphatase 2, regulatory subunit B' gamma isoform  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Ppp2r5c  protein phosphatase 2, regulatory subunit B' gamma isoform  LOC691318  similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B su...  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC691318  similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B su...  RGD1564600_predicted  similar to protein phosphatase 2A B56 regulatory subunit gamma 3 isoform (predicted)  Data merged from RGD:1564600 1643240 APPROVED
2006-11-19 LOC691318  similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B su...      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684586  similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PP2A, B subunit, B gamma isoform) (PP2A, B subunit, B56 gamma isoform) (PP2A, B subunit, PR61 gamma isoform) (PP2A, B subunit, R5 gamma isoform) (PP2A, B su...      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1564600_predicted  similar to protein phosphatase 2A B56 regulatory subunit gamma 3 isoform (predicted)  LOC500722  similar to protein phosphatase 2A B56 regulatory subunit gamma 3 isoform  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500722  similar to protein phosphatase 2A B56 regulatory subunit gamma 3 isoform      Symbol and Name status set to provisional 70820 PROVISIONAL