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Gene: Dync1h1 (dynein cytoplasmic 1 heavy chain 1) Rattus norvegicus
Symbol: Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
RGD ID: 2511
Description: Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Involved in cellular response to 3,3',5-triiodo-L-thyronine; cellular response to nerve growth factor stimulus; and spermatid development. Localizes to several cellular components, including manchette; neuronal cell body; and nuclear envelope. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2O; autosomal dominant non-syndromic intellectual disability 13; and spinal muscular atrophy with lower extremity predominance 1. Orthologous to human DYNC1H1 (dynein cytoplasmic 1 heavy chain 1); PARTICIPATES IN mitochondria transport pathway; phagocytosis pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: cytoplasmic dynein 1 heavy chain 1; cytoplasmic dynein heavy chain 1; DHC1a; Dnch1; Dnchc1; dynein heavy chain, cytosolic; dynein, cytoplasmic, heavy chain 1; MAP 1C; microtubule-associated protein 1 C
Homo sapiens (human) : DYNC1H1 (dynein cytoplasmic 1 heavy chain 1)  HGNC  Alliance
Mus musculus (house mouse) : Dync1h1 (dynein cytoplasmic 1 heavy chain 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dync1h1 (dynein cytoplasmic 1 heavy chain 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DYNC1H1 (dynein cytoplasmic 1 heavy chain 1)
Canis lupus familiaris (dog) : DYNC1H1 (dynein cytoplasmic 1 heavy chain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dync1h1 (dynein cytoplasmic 1 heavy chain 1)
Sus scrofa (pig) : DYNC1H1 (dynein cytoplasmic 1 heavy chain 1)
Chlorocebus sabaeus (African green monkey) : DYNC1H1 (dynein cytoplasmic 1 heavy chain 1)
Heterocephalus glaber (naked mole-rat) : Dync1h1 (dynein cytoplasmic 1 heavy chain 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06134,958,854 - 135,085,769 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6134,958,854 - 135,085,769 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,094,877 - 144,159,980 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,318,083 - 135,391,459 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16135,324,200 - 135,397,646 (+)NCBI
Celera6127,184,881 - 127,250,555 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dync1h1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2511
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.