Vrk1 (VRK serine/threonine kinase 1)

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Gene: Vrk1 (VRK serine/threonine kinase 1) Rattus norvegicus

Analyze

Symbol:

Vrk1

Name:

VRK serine/threonine kinase 1

RGD ID:

1306069

Description:

Predicted to enable histone H3 kinase activity; histone binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including DNA damage response; Golgi disassembly; and positive regulation of protein localization to chromatin. Predicted to be located in Golgi stack; cytosol; and nuclear lumen. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 1A. Orthologous to human VRK1 (VRK serine/threonine kinase 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC362779; serine/threonine-protein kinase VRK1; vaccinia related kinase 1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	VRK1 (VRK serine/threonine kinase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Vrk1 (vaccinia related kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Vrk1 (VRK serine/threonine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	VRK1 (VRK serine/threonine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	VRK1 (VRK serine/threonine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Vrk1 (VRK serine/threonine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	VRK1 (VRK serine/threonine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	VRK1 (VRK serine/threonine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Vrk1 (VRK serine/threonine kinase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	VRK1 (VRK serine/threonine kinase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Vrk1 (vaccinia related kinase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	vrk1 (VRK serine/threonine kinase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	vrk-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	ball	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	vrk1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	124,914,770 - 124,981,508 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	124,914,855 - 124,981,436 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	125,035,687 - 125,102,303 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	125,330,983 - 125,397,599 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	124,692,652 - 124,759,212 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	129,835,788 - 129,902,839 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	129,835,919 - 129,902,793 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	139,031,607 - 139,098,569 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	130,181,610 - 130,249,361 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	130,185,356 - 130,253,107 (+)	NCBI
Celera	6	122,475,358 - 122,561,934 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

hereditary breast ovarian cancer syndrome (ISO)

intellectual disability (ISO)

isolated microphthalmia 2 (ISO)

Juvenile Amyotrophic Lateral Sclerosis (ISO)

Multiple Abnormalities (ISO)

pontocerebellar hypoplasia (ISO)

pontocerebellar hypoplasia type 1 (ISO)

pontocerebellar hypoplasia type 1A (ISO)

pontocerebellar hypoplasia type 1B (ISO)

spinal muscular atrophy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2-hydroxypropanoic acid (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

calcitriol (ISO)

cannabidiol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chromium(6+) (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

dicrotophos (ISO)

Enterolactone (ISO)

enzyme inhibitor (ISO)

fipronil (EXP)

L-ascorbic acid (ISO)

N-methyl-N-nitrosourea (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (ISO)

picoxystrobin (ISO)

piroxicam (ISO)

potassium chromate (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

topotecan (EXP)

triphenyl phosphate (EXP)

troglitazone (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin remodeling (IEA)

DNA damage response (ISO)

Golgi disassembly (ISO)

positive regulation of protein localization to chromatin (ISO)

signal transduction (IBA)

Cellular Component

cytosol (IEA,ISO)

Golgi stack (ISO)

nucleolus (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,ISO)

Molecular Function

ATP binding (IEA)

histone binding (ISO)

histone H3S10 kinase activity (ISO)

histone H3T3 kinase activity (ISO)

kinase activity (ISO)

protein binding (ISO)

protein kinase activity (ISO)

protein kinase binding (ISO)

protein serine/threonine kinase activity (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:14645249	PMID:17938195	PMID:19103756	PMID:21543316	PMID:22194607	PMID:22572157

Genomics

Comparative Map Data

Vrk1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	124,914,770 - 124,981,508 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	124,914,855 - 124,981,436 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	125,035,687 - 125,102,303 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	125,330,983 - 125,397,599 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	124,692,652 - 124,759,212 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	129,835,788 - 129,902,839 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	129,835,919 - 129,902,793 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	139,031,607 - 139,098,569 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	130,181,610 - 130,249,361 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	130,185,356 - 130,253,107 (+)	NCBI
Celera	6	122,475,358 - 122,561,934 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

VRK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	96,797,382 - 96,881,609 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	96,797,304 - 96,954,846 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	97,263,719 - 97,347,946 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	96,333,437 - 96,417,704 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	96,333,467 - 96,417,693	NCBI
Celera	14	77,319,099 - 77,403,366 (+)	NCBI		Celera
Cytogenetic Map	14	q32.2	NCBI
HuRef	14	77,447,214 - 77,531,474 (+)	NCBI		HuRef
CHM1_1	14	97,202,026 - 97,286,310 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	91,029,172 - 91,113,426 (+)	NCBI		T2T-CHM13v2.0

Vrk1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	105,976,398 - 106,044,577 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	105,976,487 - 106,043,685 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	106,010,139 - 106,078,318 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	106,010,228 - 106,077,426 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	107,248,473 - 107,315,620 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	106,411,313 - 106,478,460 (+)	NCBI		MGSCv36	mm8
Celera	12	107,246,468 - 107,313,845 (+)	NCBI		Celera
Cytogenetic Map	12	E- F1	NCBI
cM Map	12	56.37	NCBI

Vrk1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	18,508,769 - 18,595,704 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	18,508,915 - 18,595,104 (+)	NCBI	ChiLan1.0	ChiLan1.0

VRK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	14	97,176,724 - 97,261,065 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	77,429,970 - 77,514,217 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	96,783,489 - 96,831,954 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	96,756,397 - 96,831,954 (+)	Ensembl	panpan1.1		panPan2

VRK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	65,444,404 - 65,551,348 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	65,443,949 - 65,551,151 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	64,961,338 - 65,068,324 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	65,718,203 - 65,825,229 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	65,717,954 - 65,825,232 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	65,390,164 - 65,497,054 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	65,451,536 - 65,558,390 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	65,775,210 - 65,882,284 (+)	NCBI		UU_Cfam_GSD_1.0

Vrk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	8,985,074 - 9,071,452 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936604	1,011,052 - 1,097,403 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936604	1,011,048 - 1,097,388 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VRK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	117,942,973 - 118,028,923 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	117,942,929 - 118,025,991 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	125,203,973 - 125,310,693 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

VRK1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	74,686,102 - 74,770,496 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	74,686,111 - 74,770,874 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	61,835,736 - 61,920,212 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vrk1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	6,595,814 - 6,678,081 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	6,595,827 - 6,678,139 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Vrk1
88 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	177
Count of miRNA genes:	112
Interacting mature miRNAs:	119
Transcripts:	ENSRNOT00000036035
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
738034	Anxrr5	Anxiety related response QTL 5	5.9		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	6	84130881	129130881	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	85140138	130140138	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	85140138	130140138	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
1300076	Glom8	Glomerulus QTL 8	7	0.000000009	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	86894788	131894788	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	93701310	128713626	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	94968928	137848904	Rat
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	94968928	139968928	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	96833997	140994061	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	100364669	140994061	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	100671796	132340886	Rat
1331797	Bp213	Blood pressure QTL 213	3.291		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	104085867	128713626	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	105156861	140994061	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	106752656	132339866	Rat
737976	Pia24	Pristane induced arthritis QTL 24			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	6	112636280	140994061	Rat
1298087	Iddm18	Insulin dependent diabetes mellitus QTL 18		0.0001	urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	6	116506292	130245370	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	122549046	137801795	Rat
2293085	Iddm29	Insulin dependent diabetes mellitus QTL 29	7.66		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	122549046	140286318	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	122549046	140994061	Rat

Markers in Region

BF416556

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	124,921,695 - 124,921,788 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	129,842,260 - 129,842,352	NCBI	Rnor6.0
Rnor_5.0	6	139,037,990 - 139,038,082	UniSTS	Rnor5.0
RGSC_v3.4	6	130,188,403 - 130,188,495	UniSTS	RGSC3.4
Celera	6	122,482,134 - 122,482,226	UniSTS
Cytogenetic Map	6	q32	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	26	36	22	19	22	1	1	74	23	41	11	1
Low		17	21	19		19	7	10		12			7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240530	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112540	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112543	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112544	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000036035 ⟹ ENSRNOP00000029546

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	124,914,855 - 124,981,436 (+)	Ensembl
Rnor_6.0 Ensembl	6	129,835,919 - 129,902,793 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000098742 ⟹ ENSRNOP00000090784

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	124,914,911 - 124,977,374 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000100741 ⟹ ENSRNOP00000093032

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	124,914,890 - 124,981,246 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000102103 ⟹ ENSRNOP00000084211

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	124,914,911 - 124,981,125 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104154 ⟹ ENSRNOP00000077410

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	124,914,911 - 124,981,125 (+)	Ensembl

RefSeq Acc Id:

NM_001012194 ⟹ NP_001012194

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,901 - 124,981,463 (+)	NCBI
Rnor_6.0	6	129,835,919 - 129,902,794 (+)	NCBI
Rnor_5.0	6	139,031,607 - 139,098,569 (+)	NCBI
RGSC_v3.4	6	130,181,610 - 130,249,361 (+)	RGD
Celera	6	122,475,358 - 122,561,934 (+)	RGD

Sequence:

show sequence

TTCGTACTACGCTGTGGGACGGCGAGTTGGCCGCTCTGGGTAGGGAGCCCTGAGGTGGCGGCGG
GACGGTGGGTACAGCGACGCATCAGAGAGGCGCCTGCTCATCCGGGTGTCAGGCGGCGCGGCTG
CTGGGTCGGGTCAGCCCGGGAACCCTCGCCTCTCTGCCCGCTCGCGGAGCTGCCGGAAGCCCGG
TTCTAGAAGGCCGCCCGAAGCCTGGACAGGGCCAGGTGGCGGACACCGGGACAGGAATCTGGAC
CGGCCGAGCTTGCCTCTTCCTTAGCAGCGGTGAGTGAAAATGCCTCGTGTAAAAGCAGCTCAGG
CTGGAAGACAGGGACCTGCAAAGAGGCGCCTCGCAGAGCAGTTTGCCGCTGGAGAGATCATAAC
CGACATGTCTAAAAAGGAATGGAAACTAGGCTTGCCTATTGGCCAAGGAGGCTTTGGCTGCATC
TATCTGGCGGACACAAATTCTTCCAAACCGGTCGGCAGTGATGCGCCCTGTGTTGTGAAAGTGG
AACCCAGTGACAATGGACCTCTTTTCACTGAATTAAAGTTCTACCAGAGGGCTGCTAAACCAGA
GCAAATTCAGAAATGGATTCATACACATAAATTGAAGTATCTTGGTGTTCCTAAGTATTGGGGA
TCTGGTCTACATGATAAAAATGGAAAAAGTTACAGGTTTATGATAATGGACCGCTTTGGGAGTG
ACCTTCAGAAAATATATGAAGCAAATGCCAAAAGGTTTTCTCGGAAAACTGTCTTGCAGCTAAG
CTTAAGAATTCTGGATATCCTGGAGTACATCCACGAGCACGAGTATGTGCATGGGGACATCAAG
GCCTCCAACCTCCTTCTGAGTTACAAGAACCCTGACCAGGTGTATTTGGTTGACTATGGACTTG
CTTATCGGTACTGCCCAGATGGAGTTCATAAAGAGTACAAGGAAGATCCCAAAAGGTGCCACGA
CGGCACACTGGAGTTCACCAGCATCGATGCTCACAATGGCGTGGCCCCATCTCGACGTGGTGAT
TTGGAAATACTTGGTTACTGCATGATCCAGTGGCTCAGCGGCTGTCTTCCTTGGGAGGATAACT
TGAAAGACCCCAACTACGTCAGACAGTCCAAAATTAGATACAGAGACAATGTCGCAGCTTTGAT
GGAGAAATGCTTTCCTGAGAGGAATAAGCCAGGTGAGATCGCTAAGTACATGGAGACTGTGAAA
CTACTGGACTACACTGAAAAGCCGCTTTACCAAAACCTACGTGACATCCTTCTGCAAGGACTAA
AAGCTATAGGAAGTAAGGATGACGGCAAACTGGATTTTAGTGCTGTGGAGAACGGAAGTGTGAA
CACAAAACCAGCTTCAAAGAAGCGGAAGAAAGGCGCTGTGGAAGAAGAAAGCTCAGTGTGCGCT
GTGGAAGAAAGCCCAGTGTGCGCTGTGGAAGAAAGCCCAGTGTGCGCCGTGGAAGACATGGAGT
GCGCAGACACACAGGCGCAAGAGGCCATACAGACTCGTTCACGAACCAGAAAGAAAGCCCAGCA
ATAACTGAGATGCCAGAAACCGTCTTCTCTGCCTGTTCATTTGACTGTTTCCTCCTTTTCTATT
TTATGTTTTATTTTCATGTGAGTCTTGTGGGGTGTGAGTAATAATTGAATGACTACTTTTTTGA
AAAGCAAACTTTATTAAAATGAGTATTTTGTGTACTTTATTGAAGGATTATTTATAAAGTCTCA
AATCTTTAGTCGTCACAACCCACGTGCTTTGGGACTTGGGAGCGTGTGCTGGCTCTGGCCGCTC
TGCACTTCCCAGGTTGGGCAGAGCTCTCTACAGGCTCCTTGCTTTTACGGAATGAAGAACTTAA
AATAAAGGTCTCTTTTGCTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006240530 ⟹ XP_006240592

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,796 - 124,981,508 (+)	NCBI
Rnor_6.0	6	129,835,881 - 129,902,839 (+)	NCBI
Rnor_5.0	6	139,031,607 - 139,098,569 (+)	NCBI

Sequence:

show sequence

GCCGTGGGCAAGTCGCAAGTCTAGAAAGCGGCGGGAAGTTCGTACTACGCTGTGGGACGGCGAG
TTGGCCGCTCTGGTGAAAATGCCTCGTGTAAAAGCAGCTCAGGCTGGAAGACAGGGACCTGCAA
AGAGGCGCCTCGCAGAGCAGTTTGCCGCTGGAGAGATCATAACCGACATGTCTAAAAAGGAATG
GAAACTAGGCTTGCCTATTGGCCAAGGAGGCTTTGGCTGCATCTATCTGGCGGACACAAATTCT
TCCAAACCGGTCGGCAGTGATGCGCCCTGTGTTGTGAAAGTGGAACCCAGTGACAATGGACCTC
TTTTCACTGAATTAAAGTTCTACCAGAGGGCTGCTAAACCAGAGCAAATTCAGAAATGGATTCA
TACACATAAATTGAAGTATCTTGGTGTTCCTAAGTATTGGGGATCTGGTCTACATGATAAAAAT
GGAAAAAGTTACAGGTTTATGATAATGGACCGCTTTGGGAGTGACCTTCAGAAAATATATGAAG
CAAATGCCAAAAGGTTTTCTCGGAAAACTGTCTTGCAGCTAAGCTTAAGAATTCTGGATATCCT
GGAGTACATCCACGAGCACGAGTATGTGCATGGGGACATCAAGGCCTCCAACCTCCTTCTGAGT
TACAAGAACCCTGACCAGGTGTATTTGGTTGACTATGGACTTGCTTATCGGTACTGCCCAGATG
GAGTTCATAAAGAGTACAAGGAAGATCCCAAAAGGTGCCACGACGGCACACTGGAGTTCACCAG
CATCGATGCTCACAATGGCGTGGCCCCATCTCGACGTGGTGATTTGGAAATACTTGGTTACTGC
ATGATCCAGTGGCTCAGCGGCTGTCTTCCTTGGGAGGATAACTTGAAAGACCCCAACTACGTCA
GACAGTCCAAAATTAGATACAGAGACAATGTCGCAGCTTTGATGGAGAAATGCTTTCCTGAGAG
GAATAAGCCAGGTGAGATCGCTAAGTACATGGAGACTGTGAAACTACTGGACTACACTGAAAAG
CCGCTTTACCAAAACCTACGTGACATCCTTCTGCAAGGACTAAAAGCTATAGGAAGTAAGGATG
ACGGCAAACTGGATTTTAGTGCTGTGGAGAACGGAAGTGTGAACACAAAACCAGCTTCAAAGAA
GCGGAAGAAAGGCGCTGTGGAAGAAGAAAGCTCAGTGTGCGCTGTGGAAGAAAGCCCAGTGTGC
GCTGTGGAAGAAAGCCCAGTGTGCGCCGTGGAAGACATGGAGTGCGCAGACACACAGGCGCAAG
AGGCCATACAGACTCGTTCACGAACCAGAAAGAAAGCCCAGCAATAACTGAGATGCCAGAAACC
GTCTTCTCTGCCTGTTCATTTGACTGTTTCCTCCTTTTCTATTTTATGTTTTATTTTCATGTGA
GTCTTGTGGGGTGTGAGTAATAATTGAATGACTACTTTTTTGAAAAGCAAACTTTATTAAAATG
AGTATTTTGTGTACTTTATTGAAGGATTATTTATAAAGTCTCAAATCTTTAGTCGTCACAACCC
ACGTGCTTTGGGACTTGGGAGCGTGTGCTGGCTCTGGCCGCTCTGCACTTCCCAGGTTGGGCAG
AGCTCTCTACAGGCTCCTTGCTTTTACGGAATGAAGAACTTAAAATAAAGGTCTCTTTTGCTTT
ACGTAGTATACAATTTGTTGCGACAATAAAGTTTGGTCTACCTGGA

hide sequence

RefSeq Acc Id:

XM_006240531 ⟹ XP_006240593

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,822 - 124,981,508 (+)	NCBI
Rnor_6.0	6	129,835,895 - 129,902,839 (+)	NCBI
Rnor_5.0	6	139,031,607 - 139,098,569 (+)	NCBI

Sequence:

show sequence

GCAAGTCTAGAAAGCGGCGGGAAGTTCGTACTACGCTGTGGGACGGCGAGTTGGCCGCTCTGGG
TAGGGAGCCCTGAGGTGGCGGCGGGACGTGAAAATGCCTCGTGTAAAAGCAGCTCAGGCTGGAA
GACAGGGACCTGCAAAGAGGCGCCTCGCAGAGCAGTTTGCCGCTGGAGAGATCATAACCGACAT
GTCTAAAAAGGAATGGAAACTAGGCTTGCCTATTGGCCAAGGAGGCTTTGGCTGCATCTATCTG
GCGGACACAAATTCTTCCAAACCGGTCGGCAGTGATGCGCCCTGTGTTGTGAAAGTGGAACCCA
GTGACAATGGACCTCTTTTCACTGAATTAAAGTTCTACCAGAGGGCTGCTAAACCAGAGCAAAT
TCAGAAATGGATTCATACACATAAATTGAAGTATCTTGGTGTTCCTAAGTATTGGGGATCTGGT
CTACATGATAAAAATGGAAAAAGTTACAGGTTTATGATAATGGACCGCTTTGGGAGTGACCTTC
AGAAAATATATGAAGCAAATGCCAAAAGGTTTTCTCGGAAAACTGTCTTGCAGCTAAGCTTAAG
AATTCTGGATATCCTGGAGTACATCCACGAGCACGAGTATGTGCATGGGGACATCAAGGCCTCC
AACCTCCTTCTGAGTTACAAGAACCCTGACCAGGTGTATTTGGTTGACTATGGACTTGCTTATC
GGTACTGCCCAGATGGAGTTCATAAAGAGTACAAGGAAGATCCCAAAAGGTGCCACGACGGCAC
ACTGGAGTTCACCAGCATCGATGCTCACAATGGCGTGGCCCCATCTCGACGTGGTGATTTGGAA
ATACTTGGTTACTGCATGATCCAGTGGCTCAGCGGCTGTCTTCCTTGGGAGGATAACTTGAAAG
ACCCCAACTACGTCAGACAGTCCAAAATTAGATACAGAGACAATGTCGCAGCTTTGATGGAGAA
ATGCTTTCCTGAGAGGAATAAGCCAGGTGAGATCGCTAAGTACATGGAGACTGTGAAACTACTG
GACTACACTGAAAAGCCGCTTTACCAAAACCTACGTGACATCCTTCTGCAAGGACTAAAAGCTA
TAGGAAGTAAGGATGACGGCAAACTGGATTTTAGTGCTGTGGAGAACGGAAGTGTGAACACAAA
ACCAGCTTCAAAGAAGCGGAAGAAAGGCGCTGTGGAAGAAGAAAGCTCAGTGTGCGCTGTGGAA
GAAAGCCCAGTGTGCGCTGTGGAAGAAAGCCCAGTGTGCGCCGTGGAAGACATGGAGTGCGCAG
ACACACAGGCGCAAGAGGCCATACAGACTCGTTCACGAACCAGAAAGAAAGCCCAGCAATAACT
GAGATGCCAGAAACCGTCTTCTCTGCCTGTTCATTTGACTGTTTCCTCCTTTTCTATTTTATGT
TTTATTTTCATGTGAGTCTTGTGGGGTGTGAGTAATAATTGAATGACTACTTTTTTGAAAAGCA
AACTTTATTAAAATGAGTATTTTGTGTACTTTATTGAAGGATTATTTATAAAGTCTCAAATCTT
TAGTCGTCACAACCCACGTGCTTTGGGACTTGGGAGCGTGTGCTGGCTCTGGCCGCTCTGCACT
TCCCAGGTTGGGCAGAGCTCTCTACAGGCTCCTTGCTTTTACGGAATGAAGAACTTAAAATAAA
GGTCTCTTTTGCTTTACGTAGTATACAATTTGTTGCGACAATAAAGTTTGGTCTACCTGGA

hide sequence

RefSeq Acc Id:

XM_006240532 ⟹ XP_006240594

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,770 - 124,981,508 (+)	NCBI
Rnor_6.0	6	129,836,250 - 129,902,839 (+)	NCBI
Rnor_5.0	6	139,031,607 - 139,098,569 (+)	NCBI

Sequence:

show sequence

TCCTCCCTGGCCTTGCTCCACAGGTCTCCACCGCCGGTGACCTGTCTCCTGTTGCAGTGTCTTC
AGAGGCAAGCAGTGAAAATGCCTCGTGTAAAAGCAGCTCAGGCTGGAAGACAGGGACCTGCAAA
GAGGCGCCTCGCAGAGCAGTTTGCCGCTGGAGAGATCATAACCGACATGTCTAAAAAGGAATGG
AAACTAGGCTTGCCTATTGGCCAAGGAGGCTTTGGCTGCATCTATCTGGCGGACACAAATTCTT
CCAAACCGGTCGGCAGTGATGCGCCCTGTGTTGTGAAAGTGGAACCCAGTGACAATGGACCTCT
TTTCACTGAATTAAAGTTCTACCAGAGGGCTGCTAAACCAGAGCAAATTCAGAAATGGATTCAT
ACACATAAATTGAAGTATCTTGGTGTTCCTAAGTATTGGGGATCTGGTCTACATGATAAAAATG
GAAAAAGTTACAGGTTTATGATAATGGACCGCTTTGGGAGTGACCTTCAGAAAATATATGAAGC
AAATGCCAAAAGGTTTTCTCGGAAAACTGTCTTGCAGCTAAGCTTAAGAATTCTGGATATCCTG
GAGTACATCCACGAGCACGAGTATGTGCATGGGGACATCAAGGCCTCCAACCTCCTTCTGAGTT
ACAAGAACCCTGACCAGGTGTATTTGGTTGACTATGGACTTGCTTATCGGTACTGCCCAGATGG
AGTTCATAAAGAGTACAAGGAAGATCCCAAAAGGTGCCACGACGGCACACTGGAGTTCACCAGC
ATCGATGCTCACAATGGCGTGGCCCCATCTCGACGTGGTGATTTGGAAATACTTGGTTACTGCA
TGATCCAGTGGCTCAGCGGCTGTCTTCCTTGGGAGGATAACTTGAAAGACCCCAACTACGTCAG
ACAGTCCAAAATTAGATACAGAGACAATGTCGCAGCTTTGATGGAGAAATGCTTTCCTGAGAGG
AATAAGCCAGGTGAGATCGCTAAGTACATGGAGACTGTGAAACTACTGGACTACACTGAAAAGC
CGCTTTACCAAAACCTACGTGACATCCTTCTGCAAGGACTAAAAGCTATAGGAAGTAAGGATGA
CGGCAAACTGGATTTTAGTGCTGTGGAGAACGGAAGTGTGAACACAAAACCAGCTTCAAAGAAG
CGGAAGAAAGGCGCTGTGGAAGAAGAAAGCTCAGTGTGCGCTGTGGAAGAAAGCCCAGTGTGCG
CTGTGGAAGAAAGCCCAGTGTGCGCCGTGGAAGACATGGAGTGCGCAGACACACAGGCGCAAGA
GGCCATACAGACTCGTTCACGAACCAGAAAGAAAGCCCAGCAATAACTGAGATGCCAGAAACCG
TCTTCTCTGCCTGTTCATTTGACTGTTTCCTCCTTTTCTATTTTATGTTTTATTTTCATGTGAG
TCTTGTGGGGTGTGAGTAATAATTGAATGACTACTTTTTTGAAAAGCAAACTTTATTAAAATGA
GTATTTTGTGTACTTTATTGAAGGATTATTTATAAAGTCTCAAATCTTTAGTCGTCACAACCCA
CGTGCTTTGGGACTTGGGAGCGTGTGCTGGCTCTGGCCGCTCTGCACTTCCCAGGTTGGGCAGA
GCTCTCTACAGGCTCCTTGCTTTTACGGAATGAAGAACTTAAAATAAAGGTCTCTTTTGCTTTA
CGTAGTATACAATTTGTTGCGACAATAAAGTTTGGTCTACCTGGA

hide sequence

RefSeq Acc Id:

XM_039112534 ⟹ XP_038968462

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,770 - 124,981,508 (+)	NCBI

RefSeq Acc Id:

XM_039112535 ⟹ XP_038968463

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,832 - 124,981,508 (+)	NCBI

RefSeq Acc Id:

XM_039112536 ⟹ XP_038968464

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,832 - 124,981,508 (+)	NCBI

RefSeq Acc Id:

XM_039112537 ⟹ XP_038968465

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,831 - 124,981,508 (+)	NCBI

RefSeq Acc Id:

XM_039112538 ⟹ XP_038968466

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,832 - 124,981,508 (+)	NCBI

RefSeq Acc Id:

XM_039112540 ⟹ XP_038968468

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,806 - 124,981,508 (+)	NCBI

RefSeq Acc Id:

XM_039112541 ⟹ XP_038968469

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,926,067 - 124,981,508 (+)	NCBI

RefSeq Acc Id:

XM_039112542 ⟹ XP_038968470

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,770 - 124,981,508 (+)	NCBI

RefSeq Acc Id:

XM_039112543 ⟹ XP_038968471

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,914,795 - 124,981,257 (+)	NCBI

RefSeq Acc Id:

XM_039112544 ⟹ XP_038968472

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	124,943,681 - 124,981,508 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012194	(Get FASTA)	NCBI Sequence Viewer
	XP_006240592	(Get FASTA)	NCBI Sequence Viewer
	XP_006240593	(Get FASTA)	NCBI Sequence Viewer
	XP_006240594	(Get FASTA)	NCBI Sequence Viewer
	XP_038968462	(Get FASTA)	NCBI Sequence Viewer
	XP_038968463	(Get FASTA)	NCBI Sequence Viewer
	XP_038968464	(Get FASTA)	NCBI Sequence Viewer
	XP_038968465	(Get FASTA)	NCBI Sequence Viewer
	XP_038968466	(Get FASTA)	NCBI Sequence Viewer
	XP_038968468	(Get FASTA)	NCBI Sequence Viewer
	XP_038968469	(Get FASTA)	NCBI Sequence Viewer
	XP_038968470	(Get FASTA)	NCBI Sequence Viewer
	XP_038968471	(Get FASTA)	NCBI Sequence Viewer
	XP_038968472	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79130	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001012194 ⟸ NM_001012194

- UniProtKB:

Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPRVKAAQAGRQGPAKRRLAEQFAAGEIITDMSKKEWKLGLPIGQGGFGCIYLADTNSSKPVGS
DAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIHTHKLKYLGVPKYWGSGLHDKNGKSYRF
MIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSYKNPDQ
VYLVDYGLAYRYCPDGVHKEYKEDPKRCHDGTLEFTSIDAHNGVAPSRRGDLEILGYCMIQWLS
GCLPWEDNLKDPNYVRQSKIRYRDNVAALMEKCFPERNKPGEIAKYMETVKLLDYTEKPLYQNL
RDILLQGLKAIGSKDDGKLDFSAVENGSVNTKPASKKRKKGAVEEESSVCAVEESPVCAVEESP
VCAVEDMECADTQAQEAIQTRSRTRKKAQQ

hide sequence

RefSeq Acc Id:	XP_006240592 ⟸ XM_006240530
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPRVKAAQAGRQGPAKRRLAEQFAAGEIITDMSKKEWKLGLPIGQGGFGCIYLADTNSSKPVGS DAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIHTHKLKYLGVPKYWGSGLHDKNGKSYRF MIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSYKNPDQ VYLVDYGLAYRYCPDGVHKEYKEDPKRCHDGTLEFTSIDAHNGVAPSRRGDLEILGYCMIQWLS GCLPWEDNLKDPNYVRQSKIRYRDNVAALMEKCFPERNKPGEIAKYMETVKLLDYTEKPLYQNL RDILLQGLKAIGSKDDGKLDFSAVENGSVNTKPASKKRKKGAVEEESSVCAVEESPVCAVEESP VCAVEDMECADTQAQEAIQTRSRTRKKAQQ hide sequence

RefSeq Acc Id:	XP_006240593 ⟸ XM_006240531
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPRVKAAQAGRQGPAKRRLAEQFAAGEIITDMSKKEWKLGLPIGQGGFGCIYLADTNSSKPVGS DAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIHTHKLKYLGVPKYWGSGLHDKNGKSYRF MIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSYKNPDQ VYLVDYGLAYRYCPDGVHKEYKEDPKRCHDGTLEFTSIDAHNGVAPSRRGDLEILGYCMIQWLS GCLPWEDNLKDPNYVRQSKIRYRDNVAALMEKCFPERNKPGEIAKYMETVKLLDYTEKPLYQNL RDILLQGLKAIGSKDDGKLDFSAVENGSVNTKPASKKRKKGAVEEESSVCAVEESPVCAVEESP VCAVEDMECADTQAQEAIQTRSRTRKKAQQ hide sequence

RefSeq Acc Id:	XP_006240594 ⟸ XM_006240532
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPRVKAAQAGRQGPAKRRLAEQFAAGEIITDMSKKEWKLGLPIGQGGFGCIYLADTNSSKPVGS DAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIHTHKLKYLGVPKYWGSGLHDKNGKSYRF MIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKASNLLLSYKNPDQ VYLVDYGLAYRYCPDGVHKEYKEDPKRCHDGTLEFTSIDAHNGVAPSRRGDLEILGYCMIQWLS GCLPWEDNLKDPNYVRQSKIRYRDNVAALMEKCFPERNKPGEIAKYMETVKLLDYTEKPLYQNL RDILLQGLKAIGSKDDGKLDFSAVENGSVNTKPASKKRKKGAVEEESSVCAVEESPVCAVEESP VCAVEDMECADTQAQEAIQTRSRTRKKAQQ hide sequence

RefSeq Acc Id:

ENSRNOP00000029546 ⟸ ENSRNOT00000036035

RefSeq Acc Id:	XP_038968462 ⟸ XM_039112534
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968470 ⟸ XM_039112542
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AIR3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968471 ⟸ XM_039112543
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AIR3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968468 ⟸ XM_039112540
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968465 ⟸ XM_039112537
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968463 ⟸ XM_039112535
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968464 ⟸ XM_039112536
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968466 ⟸ XM_039112538
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968469 ⟸ XM_039112541
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYA2 (UniProtKB/TrEMBL), A0A8I6AIR3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968472 ⟸ XM_039112544
- Peptide Label:	isoform X3

RefSeq Acc Id:

ENSRNOP00000077410 ⟸ ENSRNOT00000104154

RefSeq Acc Id:

ENSRNOP00000093032 ⟸ ENSRNOT00000100741

RefSeq Acc Id:

ENSRNOP00000084211 ⟸ ENSRNOT00000102103

RefSeq Acc Id:

ENSRNOP00000090784 ⟸ ENSRNOT00000098742

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AYA2-F1-model_v2	AlphaFold	Q6AYA2	1-414	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306069	AgrOrtholog
BioCyc Gene	G2FUF-36324	BioCyc
Ensembl Genes	ENSRNOG00000005274	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000029546	ENTREZGENE
	ENSRNOP00000029546.5	UniProtKB/TrEMBL
	ENSRNOP00000077410.1	UniProtKB/TrEMBL
	ENSRNOP00000084211	ENTREZGENE
	ENSRNOP00000084211.1	UniProtKB/TrEMBL
	ENSRNOP00000090784.1	UniProtKB/TrEMBL
	ENSRNOP00000093032	ENTREZGENE
	ENSRNOP00000093032.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000036035	ENTREZGENE
	ENSRNOT00000036035.5	UniProtKB/TrEMBL
	ENSRNOT00000098742.1	UniProtKB/TrEMBL
	ENSRNOT00000100741	ENTREZGENE
	ENSRNOT00000100741.1	UniProtKB/TrEMBL
	ENSRNOT00000102103	ENTREZGENE
	ENSRNOT00000102103.1	UniProtKB/TrEMBL
	ENSRNOT00000104154.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7127355	IMAGE-MGC_LOAD
InterPro	Kinase-like_dom	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_prot_kinase_AS	UniProtKB/TrEMBL
KEGG Report	rno:362779	UniProtKB/TrEMBL
MGC_CLONE	MGC:94140	IMAGE-MGC_LOAD
NCBI Gene	362779	ENTREZGENE
PANTHER	CASEIN KINASE-RELATED	UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN KINASE VRK1	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PhenoGen	Vrk1	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	Kinase_like	UniProtKB/TrEMBL
UniProt	A0A8I5XW39_RAT	UniProtKB/TrEMBL
	A0A8I6AD98_RAT	UniProtKB/TrEMBL
	A0A8I6AIR3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GA19_RAT	UniProtKB/TrEMBL
	F7ENT3_RAT	UniProtKB/TrEMBL
	Q6AYA2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-08-24	Vrk1	VRK serine/threonine kinase 1	Vrk1	vaccinia related kinase 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Vrk1	vaccinia related kinase 1	Vrk1_predicted	vaccinia related kinase 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Vrk1_predicted	vaccinia related kinase 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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