Degs2 (delta(4)-desaturase, sphingolipid 2) - Rat Genome Database

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Gene: Degs2 (delta(4)-desaturase, sphingolipid 2) Rattus norvegicus
Analyze
Symbol: Degs2
Name: delta(4)-desaturase, sphingolipid 2
RGD ID: 1305023
Description: Predicted to enable sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process and sphinganine metabolic process. Predicted to act upstream of or within sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human DEGS2 (delta 4-desaturase, sphingolipid 2); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase; degenerative spermatocyte homolog 2, lipid desaturase (Drosophila); LOC314438; MGC112667; RGD1305023; similar to RIKEN cDNA 2210008A03 gene; sphingolipid 4-desaturase; sphingolipid C4-hydroxylase/delta 4-desaturase; sphingolipid C4-monooxygenase; sphingolipid delta(4)-desaturase/C4-hydroxylase DES2; sphingolipid delta(4)-desaturase/C4-monooxygenase DES2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86133,360,449 - 133,377,677 (-)NCBIGRCr8
mRatBN7.26127,596,063 - 127,613,293 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,596,071 - 127,613,293 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6127,720,188 - 127,736,719 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06128,015,247 - 128,031,780 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06127,373,386 - 127,390,379 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,591,968 - 132,608,600 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,591,969 - 132,608,600 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,762,044 - 141,778,676 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46133,021,596 - 133,037,633 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16133,028,029 - 133,043,753 (-)NCBI
Celera6125,151,076 - 125,165,766 (-)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11937514   PMID:12477932   PMID:15474011   PMID:16571104   PMID:17716801   PMID:21914808  


Genomics

Comparative Map Data
Degs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86133,360,449 - 133,377,677 (-)NCBIGRCr8
mRatBN7.26127,596,063 - 127,613,293 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,596,071 - 127,613,293 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6127,720,188 - 127,736,719 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06128,015,247 - 128,031,780 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06127,373,386 - 127,390,379 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,591,968 - 132,608,600 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,591,969 - 132,608,600 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,762,044 - 141,778,676 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46133,021,596 - 133,037,633 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16133,028,029 - 133,043,753 (-)NCBI
Celera6125,151,076 - 125,165,766 (-)NCBICelera
Cytogenetic Map6q32NCBI
DEGS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814100,143,957 - 100,166,886 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14100,143,957 - 100,159,645 (-)EnsemblGRCh38hg38GRCh38
GRCh3714100,610,294 - 100,625,982 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361499,682,509 - 99,695,712 (-)NCBINCBI36Build 36hg18NCBI36
Build 341499,682,509 - 99,695,712NCBI
Celera1480,667,585 - 80,680,837 (-)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1480,794,810 - 80,808,042 (-)NCBIHuRef
CHM1_114100,550,475 - 100,563,702 (-)NCBICHM1_1
T2T-CHM13v2.01494,377,005 - 94,399,934 (-)NCBIT2T-CHM13v2.0
Degs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912108,653,051 - 108,668,561 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12108,644,970 - 108,668,570 (-)EnsemblGRCm39 Ensembl
GRCm3812108,686,792 - 108,702,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12108,678,711 - 108,702,315 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712109,925,002 - 109,940,516 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612109,138,034 - 109,150,097 (-)NCBIMGSCv36mm8
Celera12109,922,978 - 109,938,475 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.46NCBI
Degs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543821,300,118 - 21,313,330 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543821,300,118 - 21,313,330 (-)NCBIChiLan1.0ChiLan1.0
DEGS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215101,300,362 - 101,314,035 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114100,516,856 - 100,530,535 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01480,767,334 - 80,813,506 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114100,086,782 - 100,100,741 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14100,086,782 - 100,100,741 (-)Ensemblpanpan1.1panPan2
DEGS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1868,461,461 - 68,483,685 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl868,462,555 - 68,533,062 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha867,982,593 - 68,003,272 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0868,746,674 - 68,768,529 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl868,745,809 - 68,810,392 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1868,408,727 - 68,430,548 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0868,474,055 - 68,496,021 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0868,871,727 - 68,893,581 (-)NCBIUU_Cfam_GSD_1.0
Degs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086406,211,662 - 6,260,794 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366043,817,886 - 3,839,986 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366043,821,672 - 3,839,975 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEGS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7121,058,105 - 121,076,328 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17121,058,102 - 121,131,612 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27128,592,520 - 128,599,969 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DEGS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12478,114,950 - 78,128,766 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2478,115,292 - 78,127,831 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605365,248,542 - 65,263,548 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Degs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247343,913,169 - 3,926,156 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247343,913,159 - 3,925,309 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Degs2
92 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:141
Count of miRNA genes:113
Interacting mature miRNAs:120
Transcripts:ENSRNOT00000015855
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6122549046140994061Rat
2312560Pur20Proteinuria QTL 202.10.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6125628133137801795Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6122549046137801795Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6112636280140994061Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6116506292130245370Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6122549046140286318Rat

Markers in Region
D6Got181  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,601,113 - 127,601,226 (+)MAPPERmRatBN7.2
Rnor_6.06132,597,014 - 132,597,126NCBIRnor6.0
Rnor_5.06141,767,090 - 141,767,202UniSTSRnor5.0
RGSC_v3.46133,026,644 - 133,026,751RGDRGSC3.4
RGSC_v3.46133,026,644 - 133,026,756UniSTSRGSC3.4
RGSC_v3.16133,032,831 - 133,032,943RGD
Celera6125,156,123 - 125,156,235UniSTS
RH 3.4 Map6790.1UniSTS
RH 3.4 Map6790.1RGD
RH 2.0 Map61112.2RGD
Cytogenetic Map6q32UniSTS
RH132042  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,596,171 - 127,596,361 (+)MAPPERmRatBN7.2
Rnor_6.06132,592,072 - 132,592,261NCBIRnor6.0
Rnor_5.06141,762,148 - 141,762,337UniSTSRnor5.0
RGSC_v3.46133,021,700 - 133,021,889UniSTSRGSC3.4
Celera6125,151,180 - 125,151,369UniSTS
RH 3.4 Map6791.1UniSTS
Cytogenetic Map6q32UniSTS
AI852933  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,596,283 - 127,596,403 (+)MAPPERmRatBN7.2
Rnor_6.06132,592,184 - 132,592,303NCBIRnor6.0
Rnor_5.06141,762,260 - 141,762,379UniSTSRnor5.0
RGSC_v3.46133,021,812 - 133,021,931UniSTSRGSC3.4
Celera6125,151,292 - 125,151,411UniSTS
Cytogenetic Map6q32UniSTS
D6Got181  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26127,601,114 - 127,601,221 (+)MAPPERmRatBN7.2
Rnor_6.06132,597,015 - 132,597,121NCBIRnor6.0
Rnor_5.06141,767,091 - 141,767,197UniSTSRnor5.0
RGSC_v3.46133,026,645 - 133,026,751UniSTSRGSC3.4
Celera6125,156,124 - 125,156,230UniSTS
Cytogenetic Map6q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 21 19 18 101 12
Low 94 81 51 81 127 14 83 47
Below cutoff 84 101 59 59 21 32 81 50 21

Sequence


Ensembl Acc Id: ENSRNOT00000015855   ⟹   ENSRNOP00000015855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6127,596,071 - 127,613,293 (-)Ensembl
Rnor_6.0 Ensembl6132,591,969 - 132,608,600 (-)Ensembl
RefSeq Acc Id: NM_001017457   ⟹   NP_001017457
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,360,454 - 133,377,677 (-)NCBI
mRatBN7.26127,596,068 - 127,613,293 (-)NCBI
Rnor_6.06132,591,968 - 132,608,600 (-)NCBI
Rnor_5.06141,762,044 - 141,778,676 (-)NCBI
RGSC_v3.46133,021,596 - 133,037,633 (-)RGD
Celera6125,151,076 - 125,165,766 (-)RGD
Sequence:
RefSeq Acc Id: XM_039112401   ⟹   XP_038968329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86133,360,449 - 133,373,610 (-)NCBI
mRatBN7.26127,596,063 - 127,609,222 (-)NCBI
RefSeq Acc Id: NP_001017457   ⟸   NM_001017457
- UniProtKB: Q564G3 (UniProtKB/Swiss-Prot),   A6KBH0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015855   ⟸   ENSRNOT00000015855
RefSeq Acc Id: XP_038968329   ⟸   XM_039112401
- Peptide Label: isoform X1
- UniProtKB: A6KBH0 (UniProtKB/TrEMBL)
Protein Domains
Sphingolipid delta4-desaturase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q564G3-F1-model_v2 AlphaFold Q564G3 1-323 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694820
Promoter ID:EPDNEW_R5344
Type:initiation region
Name:Degs2_1
Description:delta-desaturase, sphingolipid 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06132,608,565 - 132,608,625EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305023 AgrOrtholog
BioCyc Gene G2FUF-36287 BioCyc
Ensembl Genes ENSRNOG00000011716 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055031270 UniProtKB/Swiss-Prot
  ENSRNOG00060025186 UniProtKB/Swiss-Prot
  ENSRNOG00065024979 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000015855.7 UniProtKB/Swiss-Prot
  ENSRNOT00055054157 UniProtKB/Swiss-Prot
  ENSRNOT00060043600 UniProtKB/Swiss-Prot
  ENSRNOT00065042905 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7387212 IMAGE-MGC_LOAD
InterPro DES1/DES2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FA_desaturase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sphingolipid_d4-desaturase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:314438 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112667 IMAGE-MGC_LOAD
NCBI Gene 314438 ENTREZGENE
PANTHER SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPHINGOLIPID DELTA(4)-DESATURASE/C4-MONOOXYGENASE DES2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FA_desaturase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lipid_DES UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Degs2 PhenoGen
PIRSF Sphnglp_dlt4_des UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011716 RatGTEx
  ENSRNOG00055031270 RatGTEx
  ENSRNOG00060025186 RatGTEx
  ENSRNOG00065024979 RatGTEx
SMART Lipid_DES UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6KBH0 ENTREZGENE, UniProtKB/TrEMBL
  DEGS2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-16 Degs2  delta(4)-desaturase, sphingolipid 2  Degs2  degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Degs2  degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)  Degs2  degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Degs2  degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase  RGD1305023  similar to RIKEN cDNA 2210008A03 gene  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1305023  similar to RIKEN cDNA 2210008A03 gene  RGD1305023_predicted  similar to RIKEN cDNA 2210008A03 gene (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1305023_predicted  similar to RIKEN cDNA 2210008A03 gene (predicted)  LOC314438_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC314438_predicted  similar to RIKEN cDNA 2210008A03 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL