Rnf113a2 (ring finger protein 113A2) - Rat Genome Database

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Gene: Rnf113a2 (ring finger protein 113A2) Rattus norvegicus
Analyze
Symbol: Rnf113a2
Name: ring finger protein 113A2
RGD ID: 1303128
Description: Predicted to enable metal ion binding activity; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: zinc finger protein 183 (RING finger, C3HC4 type); Znf183
RGD Orthologs
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,794,794 - 109,796,075 (+)NCBIGRCr8
mRatBN7.26104,063,677 - 104,064,958 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6104,063,588 - 104,067,843 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,225,429 - 104,226,710 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,524,513 - 104,525,794 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,894,097 - 103,895,378 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06108,132,254 - 108,133,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06117,412,862 - 117,414,143 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,481,430 - 108,482,711 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,484,804 - 108,486,166 (+)NCBI
Celera6101,891,687 - 101,892,968 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Information Derived from GenBank Report RGD, Sept. 2003
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Rnf113a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86109,794,794 - 109,796,075 (+)NCBIGRCr8
mRatBN7.26104,063,677 - 104,064,958 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6104,063,588 - 104,067,843 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6104,225,429 - 104,226,710 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06104,524,513 - 104,525,794 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06103,894,097 - 103,895,378 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06108,132,254 - 108,133,535 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06117,412,862 - 117,414,143 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46108,481,430 - 108,482,711 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16108,484,804 - 108,486,166 (+)NCBI
Celera6101,891,687 - 101,892,968 (+)NCBICelera
Cytogenetic Map6q31NCBI
Rnf113a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391284,463,974 - 84,465,352 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1284,463,970 - 84,465,352 (+)EnsemblGRCm39 Ensembl
GRCm381284,417,200 - 84,418,578 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1284,417,196 - 84,418,578 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,758,150 - 85,759,528 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361285,306,948 - 85,308,326 (+)NCBIMGSCv36mm8
Celera1285,872,713 - 85,874,091 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1239.2NCBI


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
1331722Thshl1Thyroid stimulating hormone level QTL 111.70.0001blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)689762877106752806Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1300076Glom8Glomerulus QTL 879e-09kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000097822   ⟹   ENSRNOP00000079294
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6104,063,588 - 104,067,843 (+)Ensembl
RefSeq Acc Id: NM_001004445   ⟹   NP_001004445
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86109,794,794 - 109,796,075 (+)NCBI
mRatBN7.26104,063,677 - 104,064,958 (+)NCBI
Rnor_6.06108,132,254 - 108,133,535 (+)NCBI
Rnor_5.06117,412,862 - 117,414,143 (-)NCBI
RGSC_v3.46108,481,430 - 108,482,711 (+)RGD
Celera6101,891,687 - 101,892,968 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001004445 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI00135 (Get FASTA)   NCBI Sequence Viewer  
  AAR97522 (Get FASTA)   NCBI Sequence Viewer  
  EDL81510 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000079294.1
RefSeq Acc Id: NP_001004445   ⟸   NM_001004445
- UniProtKB: Q67ER1 (UniProtKB/TrEMBL),   A0A8I5ZN54 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000079294   ⟸   ENSRNOT00000097822
Protein Domains
C3H1-type   RING-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303128 AgrOrtholog
BioCyc Gene G2FUF-36819 BioCyc
Ensembl Genes ENSRNOG00000067995 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000097822.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Zinc finger, CCCH-type UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7133304 IMAGE-MGC_LOAD
InterPro CWC24-like UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report rno:314313 UniProtKB/TrEMBL
MGC_CLONE MGC:114206 IMAGE-MGC_LOAD
NCBI Gene 314313 ENTREZGENE
PANTHER PTHR12930 UniProtKB/TrEMBL
  RING FINGER PROTEIN 113A2 UniProtKB/TrEMBL
Pfam zf-C3HC4_3 UniProtKB/TrEMBL
  zf-CCCH UniProtKB/TrEMBL
PhenoGen Rnf113a2 PhenoGen
PROSITE ZF_C3H1 UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000067995 RatGTEx
SMART RING UniProtKB/TrEMBL
  ZnF_C3H1 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF90229 UniProtKB/TrEMBL
UniProt A0A8I5ZN54 ENTREZGENE, UniProtKB/TrEMBL
  Q67ER1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-03 Rnf113a2  ring finger protein 113A2  Znf183  zinc finger protein 183 (RING finger, C3HC4 type)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-02-14 Znf183  zinc finger protein 183 (RING finger, C3HC4 type)      Symbol and Name status set to provisional 70820 PROVISIONAL