Rab15 (RAB15, member RAS oncogene family)

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Gene: Rab15 (RAB15, member RAS oncogene family) Rattus norvegicus

Analyze

Symbol:

Rab15

Name:

RAB15, member RAS oncogene family

RGD ID:

735172

Description:

Predicted to have GTP binding activity. Predicted to be involved in several processes, including cellular response to insulin stimulus; protein localization to plasma membrane; and secretion by cell. Predicted to localize to several cellular components, including Golgi apparatus; cytoplasmic vesicle; and perinuclear region of cytoplasm. Orthologous to human RAB15 (RAB15, member RAS oncogene family); INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; 6-propyl-2-thiouracil; ammonium chloride.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

RAB15, member RAS onocogene family; Ras-related protein Rab-15

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RAB15 (RAB15, member RAS oncogene family)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Rab15 (RAB15, member RAS oncogene family)	HGNC	Treefam, EggNOG, NCBI, OMA, Inparanoid, Panther, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Rab15 (RAB15, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RAB15 (RAB15, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RAB15 (RAB15, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rab15 (RAB15, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RAB15 (RAB15, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	RAB15 (RAB15, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rab15 (RAB15, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Rab15 (RAB15, member RAS oncogene family)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	RAB15 (RAB15, member RAS oncogene family)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	rab15 (RAB15, member RAS oncogene family)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	SEC4	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	RabX4	Alliance	DIOPT (Ensembl Compara\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	95,499,584 - 95,524,073 (-)	NCBI
Rnor_6.0 Ensembl	6	99,845,954 - 99,870,024 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	6	99,845,952 - 99,870,320 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	6	109,242,425 - 109,266,332 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	99,378,937 - 99,403,340 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	6	99,382,393 - 99,406,796 (-)	NCBI
Celera	6	93,918,933 - 93,942,804 (-)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-trinitrobenzenesulfonic acid (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ISO)

6-propyl-2-thiouracil (EXP)

ammonium chloride (EXP)

arsenous acid (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP)

C60 fullerene (EXP)

choline (ISO)

cocaine (EXP)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dichlorine (EXP)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

ferric oxide (ISO)

folic acid (ISO)

furan (EXP)

genistein (EXP,ISO)

L-methionine (ISO)

lead(0) (ISO)

lead(2+) (ISO)

methoxychlor (EXP)

ozone (EXP)

phenethyl isothiocyanate (ISO)

progesterone (ISO)

SB 431542 (ISO)

silver atom (ISO)

silver(0) (ISO)

sunitinib (ISO)

tetrachloromethane (ISO)

trichloroethene (EXP)

triptonide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to insulin stimulus (IBA)

neurotransmitter secretion (TAS)

positive regulation of regulated secretory pathway (ISO)

protein localization to plasma membrane (IBA)

protein secretion (IBA)

Rab protein signal transduction (IEA)

regulation of exocytosis (IBA)

vesicle docking involved in exocytosis (IBA)

Cellular Component

cilium (ISO)

cytoplasm (ISO)

endosome (IBA)

endosome membrane (ISO)

Golgi apparatus (IBA)

insulin-responsive compartment (IBA)

membrane (TAS)

perinuclear region of cytoplasm (ISO)

plasma membrane (IBA)

recycling endosome (IBA)

synaptic vesicle (IBA)

Molecular Function

GTP binding (TAS)

GTPase activity (IEA)

protein binding (ISO)

References

References - curated


1.	Elferink LA, etal., J Biol Chem 1992 Mar 25;267(9):5768-75.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	MGD data from the GO Consortium
4.	RGD automated data pipeline
5.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:1429617	PMID:12105226	PMID:12477932	PMID:16195351	PMID:17646400	PMID:19056867	PMID:22899725	PMID:23376485

Genomics

Comparative Map Data

Rab15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	95,499,584 - 95,524,073 (-)	NCBI
Rnor_6.0 Ensembl	6	99,845,954 - 99,870,024 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	6	99,845,952 - 99,870,320 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	6	109,242,425 - 109,266,332 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	99,378,937 - 99,403,340 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	6	99,382,393 - 99,406,796 (-)	NCBI
Celera	6	93,918,933 - 93,942,804 (-)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

RAB15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	14	64,945,814 - 64,973,226 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	14	64,945,816 - 64,972,336 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	14	65,412,534 - 65,439,054 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	64,482,287 - 64,508,551 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	14	64,482,287 - 64,508,551	NCBI
Celera	14	45,467,116 - 45,493,459 (-)	NCBI
Cytogenetic Map	14	q23.3	NCBI
HuRef	14	45,582,156 - 45,608,228 (-)	NCBI		HuRef
CHM1_1	14	65,350,701 - 65,377,061 (-)	NCBI		CHM1_1

Rab15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	76,844,734 - 76,869,532 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	12	76,844,734 - 76,869,682 (-)	Ensembl
GRCm38	12	76,797,960 - 76,822,759 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	76,797,960 - 76,822,908 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	77,898,950 - 77,923,511 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	12	77,716,802 - 77,741,361 (-)	NCBI			mm8
Celera	12	77,880,317 - 77,904,917 (-)	NCBI		Celera
Cytogenetic Map	12	C3	NCBI

Rab15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955466	4,958,414 - 4,981,464 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955466	4,958,414 - 4,981,464 (+)	NCBI	ChiLan1.0	ChiLan1.0

RAB15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	14	64,408,591 - 64,435,016 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	14	45,529,223 - 45,555,895 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

RAB15
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	39,329,754 - 39,364,000 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	39,330,557 - 39,335,590 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	39,021,097 - 39,056,403 (-)	NCBI
ROS_Cfam_1.0	8	39,551,806 - 39,587,131 (-)	NCBI
UMICH_Zoey_3.1	8	39,172,610 - 39,208,151 (-)	NCBI
UNSW_CanFamBas_1.0	8	39,245,370 - 39,280,887 (-)	NCBI
UU_Cfam_GSD_1.0	8	39,604,428 - 39,640,008 (-)	NCBI

Rab15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	65,569,044 - 65,598,245 (+)	NCBI
SpeTri2.0	NW_004936495	8,590,844 - 8,622,655 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAB15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	89,015,042 - 89,039,484 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	89,015,041 - 89,039,482 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	95,395,973 - 95,402,824 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAB15
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	42,160,949 - 42,185,098 (-)	NCBI
Vero_WHO_p1.0	NW_023666053	30,328,691 - 30,374,327 (-)	NCBI

Rab15
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624734	36,062,726 - 36,083,841 (+)	NCBI

Position Markers

RH133654

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	95,499,670 - 95,499,857 (+)	MAPPER
Rnor_6.0	6	99,846,039 - 99,846,225	NCBI	Rnor6.0
Rnor_5.0	6	109,242,512 - 109,242,698	UniSTS	Rnor5.0
RGSC_v3.4	6	99,379,024 - 99,379,210	UniSTS	RGSC3.4
Celera	6	93,919,020 - 93,919,206	UniSTS
Cytogenetic Map	6	q24	UniSTS

BI284471

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	95,499,984 - 95,500,203 (+)	MAPPER
Rnor_6.0	6	99,846,353 - 99,846,571	NCBI	Rnor6.0
Rnor_5.0	6	109,242,826 - 109,243,044	UniSTS	Rnor5.0
RGSC_v3.4	6	99,379,338 - 99,379,556	UniSTS	RGSC3.4
Celera	6	93,919,334 - 93,919,552	UniSTS
RH 3.4 Map	6	669.8	UniSTS
Cytogenetic Map	6	q24	UniSTS

BI296877

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	95,504,070 - 95,504,288 (+)	MAPPER
Rnor_6.0	6	99,850,439 - 99,850,656	NCBI	Rnor6.0
Rnor_5.0	6	109,246,912 - 109,247,129	UniSTS	Rnor5.0
RGSC_v3.4	6	99,383,424 - 99,383,641	UniSTS	RGSC3.4
Celera	6	93,923,420 - 93,923,637	UniSTS
RH 3.4 Map	6	670.2	UniSTS
Cytogenetic Map	6	q24	UniSTS

RH138006

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	95,501,687 - 95,501,814 (+)	MAPPER
Rnor_6.0	6	99,848,056 - 99,848,182	NCBI	Rnor6.0
Rnor_5.0	6	109,244,529 - 109,244,655	UniSTS	Rnor5.0
RGSC_v3.4	6	99,381,041 - 99,381,167	UniSTS	RGSC3.4
Celera	6	93,921,037 - 93,921,163	UniSTS
RH 3.4 Map	6	677.0	UniSTS
Cytogenetic Map	6	q24	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	2537030	111715717	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	7009971	115379601	Rat
634330	Pia16	Pristane induced arthritis QTL 16	3.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	6	48432758	108268790	Rat
1558641	Cm47	Cardiac mass QTL 47	2.9	0.001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	6	60606431	108154445	Rat
6893332	Cm74	Cardiac mass QTL 74	0.4	0.64	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	60606431	108154445	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	62263348	107263348	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	66129520	111129520	Rat
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	68781170	147991367	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	68781170	147991367	Rat
1641904	Alcrsp4	Alcohol response QTL 4			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	6	71206251	116206251	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	75449871	120449871	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	75623277	120276465	Rat
70196	BpQTLcluster7	Blood pressure QTL cluster 7	6.82		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	75623277	120623277	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	75623277	136143011	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	75623277	136426962	Rat
1581550	Pur8	Proteinuria QTL 8			total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	75623393	136142742	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	75623393	136142742	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	76902247	114203334	Rat
2293837	Kiddil1	Kidney dilation QTL 1	3.7		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	84763275	108464097	Rat
2293842	Kiddil3	Kidney dilation QTL 3	4.3		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	84763275	108464097	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	86422697	115379601	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	87418448	111129520	Rat
738034	Anxrr5	Anxiety related response QTL 5	5.9		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	6	88507712	133507712	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	88996335	139410483	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	89631358	134631358	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	89631358	134631358	Rat
1300076	Glom8	Glomerulus QTL 8	7	0.000000009	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	91703409	136703409	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (VE) (CMO:0000132)	6	92879510	137879510	Rat
1331722	Thshl1	Thyroid stimulating hormone level QTL 1	11.7	0.0001	blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	6	93706176	111134673	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	97949772	133849286	Rat
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	99273921	144273921	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	99273921	144792678	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	591
Count of miRNA genes:	260
Interacting mature miRNAs:	317
Transcripts:	ENSRNOT00000010043
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	12							62	20	18	11
Low		28	37	21	19	21	7	10	12	15	18		7
Below cutoff		2	13	13		13	1	1			5		1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_198749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005505481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC094954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M83679	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000010043 ⟹ ENSRNOP00000010043

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	99,845,954 - 99,870,024 (-)	Ensembl

RefSeq Acc Id:

NM_198749 ⟹ NP_942044

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	95,499,584 - 95,523,942 (-)	NCBI
Rnor_6.0	6	99,845,952 - 99,870,320 (-)	NCBI
Rnor_5.0	6	109,242,425 - 109,266,332 (-)	NCBI
RGSC_v3.4	6	99,378,937 - 99,403,340 (-)	RGD
Celera	6	93,918,933 - 93,942,804 (-)	RGD

Sequence:

show sequence

CGGGACACCCCAGGGCTTGAAAGCAGAGCTGGGACACCGCCCCGGACAGCCACAGGGTCCCCGC
CGCTCCCCTCCCCCGCTCCCGCTGCAGCGGCGGCGCAGGGGACGAGGGGAGGGCCGGCCAGGGG
CGGCAGCCGCAGCTGTCCCCTCCCACCTCCCCGCCAGCGCGAGCTTCCCCGCGCCGCGCTCCCG
CCGCAGCCGCGCTTCCCCGCGCCAGCGAGCCAGCGAGCGAGCGGGCGAGGCCAGCGCGGGGGCC
GGGCCGCTTCCTTCTCGCCACCGCGGCGTCCTGGGGCGGGCTCCGGCCGCGATGGCAGAGGCTG
AGCGGGGCTGAGCCCGCAGCCGCCTGCAGCCTTCGGGCCCCCTTGAGTCCCTGCCATGGCGAAA
CAGTACGATGTGCTATTTCGGCTACTGCTGATCGGGGACTCCGGGGTGGGCAAGACCTGCCTGC
TATGCCGCTTCACCGACAACGAGTTCCACTCCTCGCATATCTCCACCATCGGTGTTGACTTTAA
GATGAAAACCATCGAAGTAGACGGCATCAAAGTGAGGATACAGATTTGGGACACAGCAGGGCAG
GAGAGGTACCAGACTATCACAAAACAGTACTACCGGCGAGCCCAGGGAATATTTTTAGTCTACG
ACATTAGCAGCGAGCGCTCTTATCAGCACATCATGAAGTGGGTCAGTGACGTGGATGAGTACGC
CCCAGAAGGCGTCCAGAAGATCCTCATCGGGAATAAGGCTGACGAAGAACAGAAACGGCAGGTG
GGGAGAGAGCAAGGGCAGCAGCTGGCTAAGGAGTATGGCATGGACTTTTACGAAACAAGTGCCT
GCACCAACCTTAACATTAAAGAGTCCTTCACTCGTCTGACCGAGCTGGTGCTGCAGGCTCACAG
GAAAGAGCTGGATGGTCTCCGAACATGTGCCAGCAATGAGCTCGCACTGGCCGAGCTGGAGGAA
GACGAAGGCAAAACTGAAGGCCCAGCAAACTCTTCAAAGACCTGCTGGTGCTGAGGGTCCTGTG
TGGAATCCTCCCTCCCCCAGTCCCCTTCCCTCAGGAGGCCCGTGGAGGCAGGGAGTCTGGGCTT
TGTCCATCACTGTCCTTTCATTTGAAGATCCTGTTGAAAACCAGTAGCTGCTACTCCCCTGCCT
GGCCCTGTGAGCAGCTTTGCTGTGGTCTCCGAGCAACCTCTGTCCCCAGCCCTGCTATCCTGGA
GTGGTAACCTTTCAACCTGTTTCCCAGCCGCAGGCCTGCTGTGACCCCAGAATGTGCTTCGACC
ATCTCACCACCCCAGGCTCCTGGGACAACGGTCAAGGCTGGAGTCAAAGCCACTTAAAGACTCC
TTTAGTGCATCTCGTGGGCTCTCTGCTTTTTCTCTTCTTTCTTCTCTTTCTCCAGTCCCTTCCT
TCCCATGTATTTTGCGTCCACGTCATCCACGTCTCTCCTCCCTAGCCTGTGTGTCCTGCTAATG
CAGTTCCTTTCTTCTTTCCTTCCTGATTCTGCCTAAGGGAATGGACCCAGGCTCTGCCCCAGGG
AGGATGGCTCACCCTGCTCTGGGCTGGGCTGAAGGCTAAGGGTGCTTCTTCCTCCTCCCCTCCC
TGCTGCCCCTTTTTGTGCCATGGGCTGCCTCCCCAATGGCCTGGGAGGTAGAACATTGAGGTAG
GAAGGAAACACTATGAGGTGGTCCTCAAGCCTGGACTGGCCTCTTCTGCCTTTGCCTTCTGCTG
GAGTTTTGGCCTTGCCTGGCTGCCTACGTGCCTCTGTGAGGACCTGAGTCCAGAGGCAGGCACA
GCAGAGAAGAAGATGACAAGATGGGGTGGCGGGGATTAAGTCACTCTGTTCTCTACCTCCCATG
CAGCGAGTGCACAGCCTTTTCACCCGGGTTCGTGGATTTAAAGATGGGATCAAGGCCTGAGGAC
GCCAGAGGGCAAGGGGATCCCCAGGGTCAGACACTGTGTAGTCAGCTGTGAGCTTGAGTTAGAG
GCCAGAGCGGATGCGAAGAGCTGGCTCCTAGATGGCAGGGTTAGGACAAGAGTAGAGGGGGCTT
CACAGAACAGTGAGTGCTGTGGTGACAGCAGGGCGGTCCCCTGTGAGGACATTTACCCAGACTC
CCTGGCAGAGGTCACAAGTGATATAGTCAATCACTCCTCGTTCACTGAACCCAGCCTTCGGAAG
TTAAGGTTTTCCCCCAGAGTCCGTGGACAACAGGCCTTAAACATGGCAAGAGAAGGGCGGGTAT
GGGTAGAATACTTGGTGCTGTTCTGCCTTCCAGGACTCCCTCCCCCTTGTTCCCTTATTTCTAA
GTCTAAGGCTGAAGCTTTGCCAACTGCTGAGTGGCTACTCAGGGAGGGAAGGACACCTCCTCCA
GAGTTCTATGCTCAGGAAGTTTCTTTAACCCTGTGGCCCAAGAGTAGCTTGAAGGAGGCCCCTC
AGAAAAAAAAAAGAAAACGAAAGCAAAAAACCAACCCTGGTAGGGTTTGTCCTTACATTCCCAA
GGTGGGAGGAGCTCAGGTAAGAGAATAGTCCCAAGATGCACTTCAAGGCTGGGTCTGGAGCCAA
ACCAAAGGAGGAGCTGGGCTCTGATGAGCATTCACTGACTGACCAGGGATTTTTTCAAATCCAG
GGCACAGCGGTGATGACAGAGAGCCTCACACCTTTTTAGTCCTCTAAAAAGGAGATGGGGATGA
AAGCAATGGGAATTCCTTCCTGACTTAGCAAGCCAGGAAGCATTCAGCGGGAGAGAACAGCTCT
GGATGTCTGGTGGAGGGAAAAGGAGACCGGGAATAGTAGGCCATTGTTCACTAAAGAGAGACAG
GGTGTTGGCTGGAAGCCTGGACCATGACTGGCTGAGGTGGCTTCCCTGGGGACTGACTCTTAGG
TAGTAGCAGGTCCTAGGTAGACTCACACAACAGTGAGCAGAGCTGCCTTCAGCCAGGGACCCGA
GGAGAGCTTCTACAGGGCACTGGCCCTAACCTGTGGCAAGTGTCACTCTCTTCTTGTCCCAGCC
CCTCAAGCAGGGACTTGATTTTTACTACCCTGGGGATTCTGGGAGGGACTCTGTACCATGGTCA
CGGCTCTGAGGTACAGCGACAGGGGACTGGGATATGAAGAACATCTGTGCTCTCTCTCTTCTGG
AGCTCGCCTCACCCTAACTGCCAGTCTGGGAAGTGGCGTGGGCTGTGTCACTGGCCTTGACTGT
TCAGCAGGCTTTCCCGCCTGTCTGCCTGTCACCCGAGATCAGCTCCCCCTGGTACATCACCCGA
GTCCCACAATCTCCCCGTGATGGGTGAACTTTGTGTACCGTGTCTTGAGTTCATTATATGAATT
GTGAGCAGGGTTCATCTATTTTAAACACAAATGTTTACAAAATAAAGAATCTTTCAAACCATAA
AAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039112017 ⟹ XP_038967945

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	95,499,584 - 95,520,747 (-)	NCBI

RefSeq Acc Id:

XM_039112018 ⟹ XP_038967946

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	95,499,584 - 95,522,783 (-)	NCBI

RefSeq Acc Id:

XR_005505481

RefSeq Status:

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	95,520,659 - 95,524,073 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_942044	(Get FASTA)	NCBI Sequence Viewer
	XP_038967945	(Get FASTA)	NCBI Sequence Viewer
	XP_038967946	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41995	(Get FASTA)	NCBI Sequence Viewer
	AAH94954	(Get FASTA)	NCBI Sequence Viewer
	EDM03678	(Get FASTA)	NCBI Sequence Viewer
	P35289	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_942044 ⟸ NM_198749

- UniProtKB:

P35289 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDT
AGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQK
RQVGREQGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELDGLRTCASNELALAE
LEEDEGKTEGPANSSKTCWC

hide sequence

RefSeq Acc Id:

ENSRNOP00000010043 ⟸ ENSRNOT00000010043

RefSeq Acc Id:	XP_038967946 ⟸ XM_039112018
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038967945 ⟸ XM_039112017
- Peptide Label:	isoform X1

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694681

Promoter ID:

EPDNEW_R5206

Type:

initiation region

Name:

Rab15_1

Description:

RAB15, member RAS oncogene family

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	99,870,118 - 99,870,178	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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CSV

TAB

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Damaging Variants

Assembly: Rnor_5.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
6	109246361	109246362	A	C	snv	FHH/EurMcwi (MCW)

Assembly: Rnor_6.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
6	99849888	99849889	A	C	snv	F344/NCrl (RGD), FHH/EurMcwi (MCW)

Assembly: RGSC_v3.4

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
6	99382873	99382874	A	C	snv	FHH/EurMcwi (MCW)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:735172	AgrOrtholog
Ensembl Genes	ENSRNOG00000007364	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000010043	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000010043	ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7316003	IMAGE-MGC_LOAD
InterPro	P-loop_NTPase	UniProtKB/Swiss-Prot
	Rab15	UniProtKB/Swiss-Prot
	Small_GTP-bd_dom	UniProtKB/Swiss-Prot
	Small_GTPase	UniProtKB/Swiss-Prot
KEGG Report	rno:299156	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:109360	IMAGE-MGC_LOAD
NCBI Gene	299156	ENTREZGENE
Pfam	Ras	UniProtKB/Swiss-Prot
PhenoGen	Rab15	PhenoGen
PROSITE	RAB	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
TIGRFAMs	small_GTP	UniProtKB/Swiss-Prot
UniProt	P35289	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q504L6	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-04	Rab15	RAB15, member RAS oncogene family	Rab15	RAB15, member RAS onocogene family	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Rab15	RAB15, member RAS onocogene family		Ras-related protein Rab-15	Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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