Gtf2a1 (general transcription factor 2A subunit 1) - Rat Genome Database

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Gene: Gtf2a1 (general transcription factor 2A subunit 1) Rattus norvegicus
Analyze
Symbol: Gtf2a1
Name: general transcription factor 2A subunit 1
RGD ID: 69246
Description: Predicted to enable several functions, including RNA polymerase II core promoter sequence-specific DNA binding activity; RNA polymerase II general transcription initiation factor activity; and general transcription initiation factor binding activity. Predicted to be involved in positive regulation of transcription initiation by RNA polymerase II and transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of transcription factor TFIIA complex; transcription factor TFIID complex; and transcription preinitiation complex. Orthologous to human GTF2A1 (general transcription factor IIA subunit 1); PARTICIPATES IN RNA polymerase II transcription initiation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: general transcription factor 2a, 1; general transcription factor II A, 1; general transcription factor IIa 1 (37kD and 19kD subunits); general transcription factor IIA subunit 1; general transcription factor IIA, 1; general transcription factor IIa, 1 (37kD and 19kD subunits); Tf2a; TfIIa; TFIIA large subunit; transcription initiation factor IIA subunit 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26110,488,891 - 110,521,059 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl6110,488,931 - 110,521,511 (-)Ensembl
Rnor_6.06115,321,110 - 115,352,659 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6115,320,467 - 115,352,681 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06124,576,129 - 124,607,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46115,180,871 - 115,210,825 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16115,184,401 - 115,214,356 (-)NCBI
Celera6108,243,380 - 108,271,421 (-)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Structural insights into transcription initiation by RNA polymerase II. Grunberg S and Hahn S, Trends Biochem Sci. 2013 Dec;38(12):603-11. doi: 10.1016/j.tibs.2013.09.002. Epub 2013 Oct 11.
4. Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription. Ma D, etal., Genes Dev 1993 Nov;7(11):2246-57.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:7724559   PMID:7958900   PMID:8626665   PMID:11159353   PMID:15927180   PMID:19235719   PMID:27193682  


Genomics

Comparative Map Data
Gtf2a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26110,488,891 - 110,521,059 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl6110,488,931 - 110,521,511 (-)Ensembl
Rnor_6.06115,321,110 - 115,352,659 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6115,320,467 - 115,352,681 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06124,576,129 - 124,607,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46115,180,871 - 115,210,825 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16115,184,401 - 115,214,356 (-)NCBI
Celera6108,243,380 - 108,271,421 (-)NCBICelera
Cytogenetic Map6q31NCBI
GTF2A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381481,175,452 - 81,221,390 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1481,175,452 - 81,221,377 (-)EnsemblGRCh38hg38GRCh38
GRCh371481,641,796 - 81,687,734 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361480,716,147 - 80,757,328 (-)NCBINCBI36hg18NCBI36
Build 341480,716,146 - 80,757,328NCBI
Celera1461,686,296 - 61,727,496 (-)NCBI
Cytogenetic Map14q31.1NCBI
HuRef1461,809,402 - 61,855,401 (-)NCBIHuRef
CHM1_11481,582,217 - 81,627,845 (-)NCBICHM1_1
T2T-CHM13v2.01475,387,683 - 75,433,560 (-)NCBI
Gtf2a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391291,522,036 - 91,559,102 (-)NCBIGRCm39mm39
GRCm39 Ensembl1291,522,036 - 91,557,261 (-)Ensembl
GRCm381291,555,262 - 91,590,487 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1291,555,262 - 91,590,487 (-)EnsemblGRCm38mm10GRCm38
MGSCv371292,793,702 - 92,828,927 (-)NCBIGRCm37mm9NCBIm37
MGSCv361291,964,272 - 91,996,044 (-)NCBImm8
Celera1292,856,544 - 92,892,065 (-)NCBICelera
Cytogenetic Map12D3NCBI
Gtf2a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554384,787,190 - 4,825,577 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554384,787,190 - 4,825,578 (-)NCBIChiLan1.0ChiLan1.0
GTF2A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11480,951,886 - 80,996,777 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1480,951,886 - 80,996,777 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01461,751,492 - 61,797,083 (-)NCBIMhudiblu_PPA_v0panPan3
GTF2A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1853,520,740 - 53,568,888 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl853,524,787 - 53,568,705 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha853,078,908 - 53,125,623 (-)NCBI
ROS_Cfam_1.0853,750,721 - 53,797,167 (-)NCBI
ROS_Cfam_1.0 Ensembl853,750,104 - 53,797,236 (-)Ensembl
UMICH_Zoey_3.1853,432,356 - 53,478,683 (-)NCBI
UNSW_CanFamBas_1.0853,436,154 - 53,482,553 (-)NCBI
UU_Cfam_GSD_1.0853,828,585 - 53,875,047 (-)NCBI
Gtf2a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864022,433,469 - 22,472,544 (+)NCBI
SpeTri2.0NW_0049364889,595,344 - 9,630,357 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF2A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7103,963,248 - 104,009,226 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17103,963,863 - 104,009,318 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27109,961,234 - 109,992,442 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GTF2A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12458,506,888 - 58,552,587 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2458,506,537 - 58,551,069 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605346,230,975 - 46,277,956 (-)NCBIVero_WHO_p1.0
Gtf2a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473420,795,474 - 20,831,234 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473420,795,550 - 20,830,602 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH138870  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26110,516,235 - 110,516,387 (+)MAPPERmRatBN7.2
Rnor_6.06115,347,706 - 115,347,857NCBIRnor6.0
Rnor_5.06124,602,685 - 124,602,836UniSTSRnor5.0
RGSC_v3.46115,205,430 - 115,205,581UniSTSRGSC3.4
Celera6108,266,754 - 108,266,905UniSTS
RH 3.4 Map6757.1UniSTS
Cytogenetic Map6q31UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:11
Count of miRNA genes:10
Interacting mature miRNAs:11
Transcripts:ENSRNOT00000005873
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 27 54 38 19 38 6 6 74 34 40 11 6
Low 16 3 3 3 2 5 1 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000005873   ⟹   ENSRNOP00000005873
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6110,488,931 - 110,521,128 (-)Ensembl
Rnor_6.0 Ensembl6115,320,467 - 115,352,681 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104002   ⟹   ENSRNOP00000086237
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6110,488,931 - 110,519,199 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119546   ⟹   ENSRNOP00000091168
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6110,488,931 - 110,521,511 (-)Ensembl
RefSeq Acc Id: NM_022208   ⟹   NP_071544
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26110,493,307 - 110,521,059 (-)NCBI
Rnor_6.06115,324,880 - 115,352,659 (-)NCBI
Rnor_5.06124,576,129 - 124,607,638 (-)NCBI
RGSC_v3.46115,180,871 - 115,210,825 (-)RGD
Celera6108,243,380 - 108,271,421 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240410   ⟹   XP_006240472
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26110,488,891 - 110,520,984 (-)NCBI
Rnor_6.06115,321,110 - 115,352,221 (-)NCBI
Rnor_5.06124,576,129 - 124,607,638 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112999   ⟹   XP_038968927
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26110,488,891 - 110,520,984 (-)NCBI
RefSeq Acc Id: XM_039113000   ⟹   XP_038968928
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26110,488,891 - 110,519,794 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_071544   ⟸   NM_022208
- UniProtKB: O08949 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240472   ⟸   XM_006240410
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000005873   ⟸   ENSRNOT00000005873
RefSeq Acc Id: XP_038968927   ⟸   XM_039112999
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038968928   ⟸   XM_039113000
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000086237   ⟸   ENSRNOT00000104002
RefSeq Acc Id: ENSRNOP00000091168   ⟸   ENSRNOT00000119546

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08949-F1-model_v2 AlphaFold O08949 1-377 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694765
Promoter ID:EPDNEW_R5289
Type:single initiation site
Name:Gtf2a1_1
Description:general transcription factor 2A subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06115,352,695 - 115,352,755EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69246 AgrOrtholog
BioCyc Gene G2FUF-36653 BioCyc
Ensembl Genes ENSRNOG00000004300 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000005873 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000086237 ENTREZGENE
  ENSRNOP00000086237.1 UniProtKB/TrEMBL
  ENSRNOP00000091168.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005873 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000104002 ENTREZGENE
  ENSRNOT00000104002.1 UniProtKB/TrEMBL
  ENSRNOT00000119546.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.18.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TFIIA_asu/bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TFIIA_b-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83830 UniProtKB/Swiss-Prot
NCBI Gene 83830 ENTREZGENE
PANTHER PTHR12694 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TFIIA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gtf2a1 PhenoGen
SMART TFIIA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50784 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A0U6_RAT UniProtKB/TrEMBL
  A0A8I6APY1_RAT UniProtKB/TrEMBL
  O08949 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-04 Gtf2a1  general transcription factor 2A subunit 1  Gtf2a1  general transcription factor IIA, 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Gtf2a1  general transcription factor IIA, 1  Gtf2a1  general transcription factor II A, 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-27 Gtf2a1  general transcription factor II A, 1  Gtf2a1  general transcription factor 2a, 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Gtf2a1  general transcription factor 2a, 1    general transcription factor 2a, 1   Symbol and Name updated 629477 APPROVED
2003-03-14 Gtf2a1  general transcription factor 2a, 1   Tf2a  TFIIA large subunit  Data Merged 628472 PROVISIONAL
2002-08-07 Tf2a  TFIIA large subunit      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Gtf2a1  general transcription factor 2a, 1       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference