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Gene: ARG2 (arginase 2) Homo sapiens
Symbol: ARG2
Name: arginase 2
Description: Exhibits arginase activity. Involved in negative regulation of tumor necrosis factor production and positive regulation of cellular senescence. Predicted to localize to mitochondrion. Implicated in asthma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: arginase II; arginase, type II; arginase-2, mitochondrial; kidney arginase; kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; non-hepatic arginase; nonhepatic arginase; type II arginase
Mus musculus (house mouse) : Arg2 (arginase type II)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arg2 (arginase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arg2 (arginase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ARG2 (arginase 2)
Canis lupus familiaris (dog) : ARG2 (arginase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arg2 (arginase 2)
Sus scrofa (pig) : ARG2 (arginase 2)
Chlorocebus sabaeus (African green monkey) : ARG2 (arginase 2)
Heterocephalus glaber (naked mole-rat) : Arg2 (arginase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1467,619,920 - 67,651,708 (+)EnsemblGRCh38hg38GRCh38
GRCh381467,619,920 - 67,651,708 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371468,086,579 - 68,118,437 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361467,156,332 - 67,188,190 (+)NCBINCBI36hg18NCBI36
Build 341467,156,331 - 67,188,190NCBI
Celera1448,145,655 - 48,177,498 (+)NCBI
Cytogenetic Map14q24.1NCBI
HuRef1448,256,285 - 48,288,134 (+)NCBIHuRef
CHM1_11468,025,216 - 68,057,216 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ARG2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732329
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.