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QTL Registration

General

QTL: Bw128 (Body weight QTL 128) Rattus norvegicus

Symbol:

Bw128

Name:

Body weight QTL 128

RGD ID:

7411545

Trait:

body mass (VT:0001259)

Measurement Type:

body weight gain (CMO:0000420)

LOD Score:

5.2

P Value:

0.001

Variance:

22.0

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	1 - 42,110,980	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	12	150,810 - 45,150,810	RGD_MAPPER_PIPELINE	Rnor_6.0
Rnor_5.0	12	2,163,091 - 47,163,091	RGD_MAPPER_PIPELINE	Rnor_5.0
RGSC_v3.4	12	1 - 43,432,667	RGD_MAPPER_PIPELINE	RGSC_v3.4

Cross Type:

intercross

Strains Crossed:

F344/IcoCrlf LOU/NimrOlaHsd

Annotation Click to see Annotation Detail View

Candidate Gene Status

	Acacb is a candidate Gene for Bw128
	Acads is a candidate Gene for Bw128

Disease Annotations Click to see Annotation Detail View

Body Weight (IAGP)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

increased body weight (IDA)

Experimental Data Annotations Click to see Annotation Detail View

Clinical Measurement

body weight gain (IDA)

Experimental Condition

control condition (IDA)

Measurement Method

body weighing method (IDA)

Vertebrate Trait

body mass (IDA)

Rat Strain

F344/IcoCrlf (IEA)

LOU/NimrOlaHsd (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	QTLs influencing carbohydrate and fat choice in a LOU/CxFischer 344 F2 rat population.	Marissal-Arvy N, etal., Obesity (Silver Spring). 2013 Apr 17. doi: 10.1002/oby.20485.

Related QTLs

Related QTL	Description	Reference
Niddm27	maps to same region	RGD:7401255

Region

Markers in Region

The following Markers overlap with this region.

RGD ID

Symbol

Expected Size

Chr

Start

Stop

Species

Match

Position Markers

Peak: (D12Mit2)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	12	19,610,870 - 19,611,091 (+)	MAPPER
Rnor_6.0	12	22,650,702 - 22,650,918	NCBI
Rnor_5.0	12	24,662,983 - 24,663,199	UniSTS
RGSC_v3.4	12	20,932,560 - 20,932,776	UniSTS
RGSC_v3.4	12	20,932,559 - 20,932,776	RGD
Celera	12	21,386,630 - 21,386,846	UniSTS
RGSC_v3.1	12	20,922,171 - 20,922,388	RGD
RH 3.4 Map	12	280.3	RGD
RH 3.4 Map	12	280.3	UniSTS
RH 2.0 Map	12	205.1	RGD
SHRSP x BN Map	12	22.7	RGD
FHH x ACI Map	12	9.01	RGD
Cytogenetic Map	12	q11-q12	UniSTS

Additional Information

RGD Curation Notes

Note Type	Note	Reference
qtl_cross_type	intercross	7401255
qtl_general	software package used: multiple interval mapping (MIM); MultiQTL software (version 2.6); ANOVA	7401255
qtl_general	measurement method: At 16 weeks of age animals were individually housed and given self-selection diet (protein, carbohydrate and fat diet in three separate cups); rats were weighed 3 times per week for 3 weeks	7401255
qtl_general	weight gain is correlated to the total calorie intake	7401255
qtl_general	number of animals used: 93 F₂ males	7401255
qtl_map	spans from 20.9-44.9 Mb; peak at 32.9 Mb	7401255

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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QTL: Bw128 (Body weight QTL 128) Rattus norvegicus

Mammalian Phenotype