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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3184
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nos1
Name: nitric oxide synthase 1
Acc ID: CHEBI:90712
Term: S-methyl-L-thiocitrulline
Definition: An L-arginine derivative in which the guanidino NH2 group of L-arginine is replaced by a methylsufanyl group.
Chemical ID: MESH:C086717
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos1decreases activityEXP 6480464CTDS-methylthiocitrulline results in decreased activity of NOS1 proteinPMID:12511180
Nos1multiple interactionsEXP 6480464CTD[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the abundance of SodiumPMID:12511180
Nos1multiple interactionsISONos1 (Mus musculus)6480464CTD[S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the susceptibility to MethamphetaminePMID:11006970
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